nimodipine has been researched along with Pain, Intractable in 2 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
Pain, Intractable: Persistent pain that is refractory to some or all forms of treatment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nimodipine was withdrawn in 5 patients during the first week of treatment due to intolerance (n = 3) or aggravation of the disease (n = 2)." | 2.67 | Enhancement of opiate analgesia by nimodipine in cancer patients chronically treated with morphine: a preliminary report. ( Flórez, J; Hurlé, MA; Maestre, JM; Santillán, R, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Santillán, R | 2 |
| Maestre, JM | 1 |
| Hurlé, MA | 2 |
| Flórez, J | 2 |
| Armijo, JA | 1 |
| de los Mozos, R | 1 |
2 trials available for nimodipine and Pain, Intractable
| Article | Year |
|---|---|
Enhancement of opiate analgesia by nimodipine in cancer patients chronically treated with morphine: a preliminary report.
Topics: Administration, Oral; Adult; Aged; Analgesia; Drug Synergism; Drug Tolerance; Female; Humans; Inject | 1994 |
Nimodipine-enhanced opiate analgesia in cancer patients requiring morphine dose escalation: a double-blind, placebo-controlled study.
Topics: Aged; Analgesics, Opioid; Biotransformation; Calcium Channel Blockers; Double-Blind Method; Drug Syn | 1998 |