nimodipine has been researched along with Neoplasms in 6 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We assessed nimodipine's ability to increase the analgesic effect of morphine in 32 patients suffering from cancer pain in a double-blind, placebo controlled cross-over study." | 9.08 | Nimodipine fails to enhance the analgesic effect of slow release morphine in the early phases of cancer pain treatment. ( Aguilar, JL; Costa, J; Gomar, C; Mazo, V; Roca, G; Vidal, F, 1996) |
| "We assessed nimodipine's ability to increase the analgesic effect of morphine in 32 patients suffering from cancer pain in a double-blind, placebo controlled cross-over study." | 5.08 | Nimodipine fails to enhance the analgesic effect of slow release morphine in the early phases of cancer pain treatment. ( Aguilar, JL; Costa, J; Gomar, C; Mazo, V; Roca, G; Vidal, F, 1996) |
| "Nimodipine was withdrawn in 5 patients during the first week of treatment due to intolerance (n = 3) or aggravation of the disease (n = 2)." | 2.67 | Enhancement of opiate analgesia by nimodipine in cancer patients chronically treated with morphine: a preliminary report. ( Flórez, J; Hurlé, MA; Maestre, JM; Santillán, R, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Piwnica-Worms, D | 1 |
| Kesarwala, AH | 1 |
| Pichler, A | 1 |
| Prior, JL | 1 |
| Sharma, V | 1 |
| Santillán, R | 2 |
| Maestre, JM | 1 |
| Hurlé, MA | 2 |
| Flórez, J | 2 |
| Roca, G | 1 |
| Aguilar, JL | 1 |
| Gomar, C | 1 |
| Mazo, V | 1 |
| Costa, J | 1 |
| Vidal, F | 1 |
| Armijo, JA | 1 |
| de los Mozos, R | 1 |
2 reviews available for nimodipine and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
Single photon emission computed tomography and positron emission tomography imaging of multi-drug resistant P-glycoprotein--monitoring a transport activity important in cancer, blood-brain barrier function and Alzheimer's disease.
Topics: Alzheimer Disease; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Tran | 2006 |
3 trials available for nimodipine and Neoplasms
| Article | Year |
|---|---|
Enhancement of opiate analgesia by nimodipine in cancer patients chronically treated with morphine: a preliminary report.
Topics: Administration, Oral; Adult; Aged; Analgesia; Drug Synergism; Drug Tolerance; Female; Humans; Inject | 1994 |
Nimodipine fails to enhance the analgesic effect of slow release morphine in the early phases of cancer pain treatment.
Topics: Administration, Oral; Adult; Aged; Analgesics, Opioid; Analysis of Variance; Calcium Channel Blocker | 1996 |
Nimodipine-enhanced opiate analgesia in cancer patients requiring morphine dose escalation: a double-blind, placebo-controlled study.
Topics: Aged; Analgesics, Opioid; Biotransformation; Calcium Channel Blockers; Double-Blind Method; Drug Syn | 1998 |
1 other study available for nimodipine and Neoplasms
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |