Page last updated: 2024-11-01

nimodipine and Muscle Spasticity

nimodipine has been researched along with Muscle Spasticity in 2 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Marcantoni, M1
Fuchs, A1
Löw, P1
Bartsch, D1
Kiehn, O1
Bellardita, C1
Li, Y1
Gorassini, MA1
Bennett, DJ1

Other Studies

2 other studies available for nimodipine and Muscle Spasticity

ArticleYear
Early delivery and prolonged treatment with nimodipine prevents the development of spasticity after spinal cord injury in mice.
    Science translational medicine, 2020, 04-15, Volume: 12, Issue:539

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Mice; Muscle Spasticity; Nimodipine; Qu

2020
Role of persistent sodium and calcium currents in motoneuron firing and spasticity in chronic spinal rats.
    Journal of neurophysiology, 2004, Volume: 91, Issue:2

    Topics: Action Potentials; Animals; Calcium Channels; Female; Motor Neurons; Muscle Spasticity; Nimodipine;

2004