Page last updated: 2024-11-01

nimodipine and Muscle Contraction

nimodipine has been researched along with Muscle Contraction in 59 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"Three kinds of contractions of rat thoracic aortic rings were used to compare suppression by CPU-86017, bepridil (Bep), verapamil (Ver), and nimodipine (Nim) in euthyroid- and Lev-induced hyperthyroidism rats."7.70p-Chlorobenzyltetrahydroberberine inhibits vascular smooth muscle contractions caused by Ca2+. ( Dai, DZ; Jiang, JM, 1998)
"Isolated pial arteries from a previously well-characterized model of experimental subarachnoid hemorrhage (SAH) in baboon were tested for their contractile response to 5-hydroxytryptamine (5-HT), norepinephrine (NE), and prostaglandin F2 alpha (PGF2 alpha) and the effect of the calcium antagonist, nimodipine."7.68Changes in contractile response and effect of a calcium antagonist, nimodipine, in isolated intracranial arteries of baboon following experimental subarachnoid hemorrhage. ( Chang, JY; Delgado, T; Owman, C; Sahlin, C; Salford, LG; Svendgaard, NA, 1990)
"Three kinds of contractions of rat thoracic aortic rings were used to compare suppression by CPU-86017, bepridil (Bep), verapamil (Ver), and nimodipine (Nim) in euthyroid- and Lev-induced hyperthyroidism rats."3.70p-Chlorobenzyltetrahydroberberine inhibits vascular smooth muscle contractions caused by Ca2+. ( Dai, DZ; Jiang, JM, 1998)
" The 5-HT2 receptor-antagonistic properties of AHR-16303B were demonstrated by inhibition of (a) [3H]ketanserin binding to rat cerebral cortical membranes (IC50 = 165 nM); (b) 5-hydroxytryptamine (5-HT)-induced foot edema in rats (minimum effective dose, (MED) = 0."3.68AHR-16303B, a novel antagonist of 5-HT2 receptors and voltage-sensitive calcium channels. ( Appell, KC; Barrett, RJ; Kilpatrick, BF; Nolan, JC; Proakis, AG; Walsh, DA, 1991)
"Isolated pial arteries from a previously well-characterized model of experimental subarachnoid hemorrhage (SAH) in baboon were tested for their contractile response to 5-hydroxytryptamine (5-HT), norepinephrine (NE), and prostaglandin F2 alpha (PGF2 alpha) and the effect of the calcium antagonist, nimodipine."3.68Changes in contractile response and effect of a calcium antagonist, nimodipine, in isolated intracranial arteries of baboon following experimental subarachnoid hemorrhage. ( Chang, JY; Delgado, T; Owman, C; Sahlin, C; Salford, LG; Svendgaard, NA, 1990)
" Dose-response curves for the 5-HT-induced contraction (from 0."1.62The combination of dantrolene and nimodipine effectively reduces 5-HT-induced vasospasms in diabetic rats. ( Crespo, MJ; García, L; Morales, M; Román, M, 2021)
"Pretreatment with iloprost did not significantly affect the concentration-response curve to any agent."1.28Relaxant effects on iloprost in canine cerebral artery. ( Cook, D; Doi, M; Kasuya, H; Weir, B; Zhang, H, 1992)
"[3H]Nitrendipine binding was sensitive to other Ca++ channel antagonists including verapamil, D-600, diltiazem, flunarizine, lidoflazine and bepridil."1.27Characterization of binding of the Ca++ channel antagonist, [3H]nitrendipine, to guinea-pig ileal smooth muscle. ( Bolger, GT; Gengo, P; Janis, RA; Klockowski, R; Luchowski, E; Siegel, H; Triggle, AM; Triggle, DJ, 1983)
"Nimodipine is a new calcium antagonist that has been advocated as a specific treatment for the cerebral vasospasm accompanying subarachnoid hemorrhage in humans because of reports that it selectively inhibits the constriction of cerebral arteries in vitro."1.26Effect of the calcium antagonist nimodipine on contractile responses of isolated canine basilar arteries induced by serotonin, prostaglandin F2 alpha, thrombin, and whole blood. ( Cunningham, MP; Robertson, JT; White, RP, 1982)

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-199018 (30.51)18.7374
1990's27 (45.76)18.2507
2000's9 (15.25)29.6817
2010's4 (6.78)24.3611
2020's1 (1.69)2.80

Authors

AuthorsStudies
Román, M1
García, L1
Morales, M1
Crespo, MJ1
Christensen, ST1
Johansson, SE1
Radziwon-Balicka, A1
Warfvinge, K1
Haanes, KA1
Edvinsson, L2
Chen, J1
Sanderson, MJ1
Wankerl, K1
Weise, D1
Gentner, R1
Rumpf, JJ1
Classen, J1
Pereira, JD1
Caricati-Neto, A1
Miranda-Ferreira, R1
Smaili, SS1
Godinho, RO1
de los Rios, C1
Léon, R1
Villaroya, M1
Samadi, A1
Marco-Contelles, J1
Jurkiewicz, NH1
Garcia, AG1
Jurkiewicz, A1
Kriz, J1
Gowing, G1
Julien, JP1
Wang, CY1
Mo, ZX1
Tu, HH1
Ghisdal, P1
Vandenberg, G1
Morel, N1
Arun, KH1
Kaul, CL1
Ramarao, P1
Badawi, JK1
Li, H1
Langbein, S1
Kwon, ST1
Kamp, S1
Bross, S1
Shen, J1
Yip, S1
Wang, Z1
Wang, W1
Xing, D1
Du, L1
Müller-Schweinitzer, E1
Neumann, P1
Makita, Y1
Kanmura, Y1
Itoh, T1
Suzuki, H1
Kuriyama, H1
Rooke, TW1
Rimele, TJ1
Vanhoutte, PM1
Spedding, M1
Bolger, GT2
Gengo, P1
Klockowski, R1
Luchowski, E1
Siegel, H1
Janis, RA1
Triggle, AM1
Triggle, DJ2
Takagi, T1
Satake, N1
Shibata, S1
Brandt, L2
Andersson, KE3
Ljunggren, B1
White, RP1
Cunningham, MP1
Robertson, JT1
Towart, R2
Wehinger, E1
Meyer, H1
Kazda, S1
Aharony, D1
Smith, JB1
Smith, EF1
Lefer, AM1
Guard, S1
Boyle, SJ1
Tang, KW1
Watling, KJ1
McKnight, AT1
Woodruff, GN1
Yao, MH1
Dai, ZX1
Xu, DZ1
Yang, ZC3
Zygmunt, PM2
Larsson, B2
Sterner, O1
Vinge, E1
Högestätt, ED5
Sunman, W1
Martin, G1
Hair, WM1
Sever, PS1
Hughes, AD1
Kase, N1
Yamura, T1
Ohnishi, H1
Nakazawa, K1
Higo, K1
Abe, K1
Tanaka, Y2
Saito, H1
Matsuki, N1
Usune, S1
Katsuragi, T1
Furukawa, T1
Okopién, B1
Trzeciak, HI1
Elliott, RA1
Norman, RI1
Parker, SG1
Whitaker, RP1
Castleden, CM1
Petersson, J1
Noguera, MA1
Ivorra, MD1
Chuliá, S1
D'Ocon, P1
Dai, DZ1
Jiang, JM1
Supinski, G1
Nethery, D1
Stofan, D1
DiMarco, A1
Kostrzewska, A1
Modzelewska, B1
Batra, S1
Liu, ZH1
Li, JL1
Li, N1
Tian, CL1
Zhang, KG1
Shigenobu, K1
Nakayama, K1
Naglie, G1
Radomski, SB1
Brymer, C1
Mathiasen, K1
O'Rourke, K1
Tomlinson, G1
Li, BY1
Zhang, YC1
Li, WH1
Gómez-Iglesias, E1
García, E1
Suarez, E1
Martínez, R1
Rodríguez-Sasiaín, JM1
Calvo, R1
Zhang, H1
Weir, B1
Doi, M1
Kasuya, H1
Cook, D1
Holmquist, F1
Kirkeby, HJ1
Forman, A1
Alm, P1
Boonen, HC1
De Mey, JG1
Barrett, RJ1
Appell, KC1
Kilpatrick, BF1
Proakis, AG1
Nolan, JC1
Walsh, DA1
Claeson, P1
Zygmunt, P1
Dong, H2
Lu, YQ1
Yang, QQ1
Wang, Q1
Alfaro, MJ1
Colado, MI1
López, F1
Martín, MI1
Wei, X1
Salom, JB1
Torregrosa, G1
Miranda, FJ1
Alabadí, JA1
Alvarez, C1
Alborch, E1
Sahlin, C1
Owman, C1
Chang, JY1
Delgado, T1
Salford, LG1
Svendgaard, NA1
Vinall, PE1
Michele, JJ1
Gordon, DA1
Simeone, FA1
Yousif, FB1
Ruzycky, A1
Arner, M1
Tsuchida, K1
Yamazaki, R1
Kaneko, K1
Aihara, H1
Owen, MP1
Joyce, EH1
Bevan, JA1
Allen, GS1
Katz, AM1
Hager, WD1
Messineo, FC1
Pappano, AJ1

Reviews

1 review available for nimodipine and Muscle Contraction

ArticleYear
Cerebral arterial spasm.
    Clinical neurosurgery, 1985, Volume: 32

    Topics: Blood Platelets; Calcium; Cerebral Arterial Diseases; Humans; Muscle Contraction; Nervous System Dis

1985

Trials

1 trial available for nimodipine and Muscle Contraction

ArticleYear
A randomized, double-blind, placebo controlled crossover trial of nimodipine in older persons with detrusor instability and urge incontinence.
    The Journal of urology, 2002, Volume: 167, Issue:2 Pt 1

    Topics: Aged; Calcium Channel Blockers; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Muscl

2002

Other Studies

57 other studies available for nimodipine and Muscle Contraction

ArticleYear
The combination of dantrolene and nimodipine effectively reduces 5-HT-induced vasospasms in diabetic rats.
    Scientific reports, 2021, 05-10, Volume: 11, Issue:1

    Topics: Animals; Calcium Channel Blockers; Dantrolene; Diabetes Mellitus, Experimental; Drug Therapy, Combin

2021
MEK1/2 inhibitor U0126, but not nimodipine, reduces upregulation of cerebrovascular contractile receptors after subarachnoid haemorrhage in rats.
    PloS one, 2019, Volume: 14, Issue:4

    Topics: Animals; Butadienes; Calcium Channel Blockers; Cerebral Arteries; Disease Models, Animal; Male; Mito

2019
Store-operated calcium entry is required for sustained contraction and Ca
    The Journal of physiology, 2017, 05-15, Volume: 595, Issue:10

    Topics: Animals; Benzamides; Calcium; Calcium Channel Blockers; Calcium Channels; Female; Lung; Methacholine

2017
L-type voltage-gated Ca2+ channels: a single molecular switch for long-term potentiation/long-term depression-like plasticity and activity-dependent metaplasticity in humans.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, May-05, Volume: 30, Issue:18

    Topics: Adult; Calcium Channel Blockers; Calcium Channels, L-Type; Dextromethorphan; Dose-Response Relations

2010
Effects of novel tacripyrines ITH12117 and ITH12118 on rat vas deferens contractions, calcium transients and cholinesterase activity.
    European journal of pharmacology, 2011, Jun-25, Volume: 660, Issue:2-3

    Topics: Acetylcholine; Acetylcholinesterase; Adenosine Triphosphate; Animals; Butyrylcholinesterase; Calcium

2011
Efficient three-drug cocktail for disease induced by mutant superoxide dismutase.
    Annals of neurology, 2003, Volume: 53, Issue:4

    Topics: Age of Onset; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Axons; Calcium Channel

2003
Effect of sinomenine on morphine dependence in isolated guinea pig ileum.
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2003, Volume: 23, Issue:4

    Topics: Animals; Guinea Pigs; Ileum; Morphinans; Morphine; Morphine Dependence; Muscle Contraction; Naloxone

2003
Rho-dependent kinase is involved in agonist-activated calcium entry in rat arteries.
    The Journal of physiology, 2003, Sep-15, Volume: 551, Issue:Pt 3

    Topics: Aluminum Compounds; Amides; Animals; Aorta; Barium; Calcium; Calcium Channel Blockers; Calcium Signa

2003
AT1 receptors and L-type calcium channels: functional coupling in supersensitivity to angiotensin II in diabetic rats.
    Cardiovascular research, 2005, Feb-01, Volume: 65, Issue:2

    Topics: Angiotensin II; Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Calcium Channels, L-Typ

2005
Inhibitory effects of L- and T-type calcium antagonists on contractions of human detrusor muscle.
    European journal of clinical pharmacology, 2006, Volume: 62, Issue:5

    Topics: Adult; Aged; Analysis of Variance; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Chann

2006
Brazilein-induced contraction of rat arterial smooth muscle involves activation of Ca2+ entry and ROK, ERK pathways.
    European journal of pharmacology, 2008, Feb-12, Volume: 580, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2008
In vitro effects of calcium antagonists PN 200-110, nifedipine, and nimodipine on human and canine cerebral arteries.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1983, Volume: 3, Issue:3

    Topics: Animals; Basilar Artery; Blood Physiological Phenomena; Calcium Channel Blockers; Cerebral Arteries;

1983
Effects of nifedipine derivatives on smooth muscle cells and neuromuscular transmission in the rabbit mesenteric artery.
    Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 324, Issue:4

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Female; In Vitro Techniques; Male; Membrane Po

1983
Contractions of the canine coronary artery in calcium-free solution.
    The American journal of physiology, 1984, Volume: 247, Issue:2 Pt 2

    Topics: Animals; Calcium; Coronary Vessels; Dinoprost; Dogs; Female; Femoral Artery; Isoproterenol; Male; Mu

1984
Functional interactions of calcium-antagonists in K+-depolarized smooth muscle.
    British journal of pharmacology, 1983, Volume: 80, Issue:3

    Topics: Animals; Calcium Channel Blockers; Diltiazem; Guinea Pigs; In Vitro Techniques; Male; Muscle Contrac

1983
Characterization of binding of the Ca++ channel antagonist, [3H]nitrendipine, to guinea-pig ileal smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:2

    Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Cinnarizine; Cobalt; Dose-Re

1983
The inhibitory action of FR 34235 (a new Ca2+ entry blocker) as compared to nimodipine and nifedipine on the contractile response to norepinephrine, potassium and 5-hydroxytryptamine in rabbit basilar artery.
    European journal of pharmacology, 1983, Jun-03, Volume: 90, Issue:2-3

    Topics: Animals; Basilar Artery; Calcium Channel Blockers; In Vitro Techniques; Male; Muscle Contraction; Mu

1983
Effects of extracellular calcium and of calcium antagonists on the contractile responses of isolated human pial and mesenteric arteries.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1981, Volume: 1, Issue:3

    Topics: Calcium; Calcium Channel Blockers; Dinoprost; Humans; Mesenteric Arteries; Muscle Contraction; Muscl

1981
Effect of the calcium antagonist nimodipine on contractile responses of isolated canine basilar arteries induced by serotonin, prostaglandin F2 alpha, thrombin, and whole blood.
    Neurosurgery, 1982, Volume: 10, Issue:3

    Topics: Animals; Basilar Artery; Blood; Calcium Channel Blockers; Dinoprost; Dogs; Female; Male; Muscle Cont

1982
The effects of nimodipine, its optical isomers and metabolites on isolated vascular smooth muscle.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:4

    Topics: Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Female; Ileum; In Vitro Techniques; Mal

1982
The selective inhibition of serotonin-induced contractions of rabbit cerebral vascular smooth muscle by calcium-antagonistic dihydropyridines. An investigation of the mechanism of action of nimodipine.
    Circulation research, 1981, Volume: 48, Issue:5

    Topics: Animals; Brain; Calcium; Female; Humans; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicotin

1981
Effects of arachidonic acid hydroperoxides on vascular and non-vascular smooth muscle.
    Prostaglandins and medicine, 1981, Volume: 7, Issue:6

    Topics: Animals; Aorta, Thoracic; Arachidonic Acids; Guinea Pigs; Ileum; In Vitro Techniques; Leukotrienes;

1981
The interaction of the NK1 receptor antagonist CP-96,345 with L-type calcium channels and its functional consequences.
    British journal of pharmacology, 1993, Volume: 110, Issue:1

    Topics: Animals; Biphenyl Compounds; Calcium Channels; Cerebral Cortex; Diltiazem; Guinea Pigs; In Vitro Tec

1993
Effects of nimodipine, felodipine, and verapamil on isolated human arteries.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1995, Volume: 16, Issue:1

    Topics: Adult; Calcium Chloride; Felodipine; Female; Humans; In Vitro Techniques; Male; Mesenteric Arteries;

1995
Calcium antagonistic properties of the sesquiterpene T-cadinol and related substances: structure-activity studies.
    Pharmacology & toxicology, 1993, Volume: 73, Issue:1

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cerebral Cortex; Dihydropyridines; Fema

1993
Effect of calcium antagonists on endothelin-induced contraction of isolated human resistance arteries: differences related to site of origin.
    Journal of human hypertension, 1993, Volume: 7, Issue:2

    Topics: Adipose Tissue; Adult; Aged; Arteries; Calcium Channel Blockers; Calcium Channels; Diltiazem; Endoth

1993
Calcium channels at the adrenergic neuroeffector junction in the rabbit ear artery.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 347, Issue:6

    Topics: Animals; Arteries; Calcium Channel Blockers; Calcium Channels; Ear; Electric Stimulation; Female; In

1993
[Pharmacological profile of F-0401, a novel dihydropyridine derivative. (2). The vasodilator action of F-0401 in isolated canine arteries].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1993, Volume: 102, Issue:2

    Topics: Animals; Arteries; Calcium Channels; Dihydropyridines; Dogs; Female; In Vitro Techniques; Male; Musc

1993
Blockade by calmodulin inhibitors of Ca2+ channels in smooth muscle from rat vas deferens.
    British journal of pharmacology, 1993, Volume: 109, Issue:1

    Topics: Animals; Barium; Calcium; Calcium Channel Blockers; Calmodulin; Imidazoles; In Vitro Techniques; Mal

1993
Discrimination by nimodipine, but not by nifedipine, between phasic and tonic contractions of guinea-pig taenia coli induced by K+ depolarization.
    Canadian journal of physiology and pharmacology, 1995, Volume: 73, Issue:11

    Topics: Animals; Calcium Channel Blockers; Colon; Dose-Response Relationship, Drug; Guinea Pigs; Hypertonic

1995
Modification of adrenergic reactivity in rat tail artery by dietary lipids and calcium channel antagonists.
    General pharmacology, 1996, Volume: 27, Issue:5

    Topics: Animals; Arteries; Body Weight; Calcium Channel Blockers; Diet, Atherogenic; Dietary Fats; In Vitro

1996
Effect of treatment with calcium antagonists in vitro and in vivo on the contractile response of isolated rat and human detrusor muscle.
    Clinical science (London, England : 1979), 1996, Volume: 91, Issue:4

    Topics: Animals; Calcium Channel Blockers; Carbachol; Electric Stimulation; Female; Humans; In Vitro Techniq

1996
Modulation by the endothelium of the inhibitory effects of pinacidil and nimodipine on endothelin-induced contraction in cerebral arteries.
    Pharmacology & toxicology, 1997, Volume: 80, Issue:1

    Topics: Animals; Basilar Artery; Calcium; Calcium Channel Blockers; Cerebral Arteries; Endothelin-1; Endothe

1997
Capacitative Ca2+ entry associated with alpha1-adrenoceptors in rat aorta.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:1

    Topics: Animals; Aorta; Benzopyrans; Calcium; Calcium Channel Blockers; Calcium Channels; Cromakalim; Glybur

1997
p-Chlorobenzyltetrahydroberberine inhibits vascular smooth muscle contractions caused by Ca2+.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1998, Volume: 19, Issue:6

    Topics: Animals; Aorta, Thoracic; Bepridil; Berberine; Biological Transport, Active; Calcium; Calcium Channe

1998
Extracellular calcium modulates generation of reactive oxygen species by the contracting diaphragm.
    Journal of applied physiology (Bethesda, Md. : 1985), 1999, Volume: 87, Issue:6

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Calcium; Calcium Channel Blockers;

1999
Source of calcium for contractile responses of large and small human intramyometrial arteries.
    Human reproduction (Oxford, England), 2000, Volume: 15, Issue:9

    Topics: Adult; Arginine Vasopressin; Arteries; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPas

2000
Effect of tetrandrine on morphine dependence in isolated guinea pig ileum.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:11

    Topics: Alkaloids; Animals; Benzylisoquinolines; Calcium Channel Blockers; Guinea Pigs; Ileum; In Vitro Tech

1999
Effects of endothelin-1 on the myogenic contraction of canine cerebral artery in response to quick stretch.
    Research communications in molecular pathology and pharmacology, 2001, Volume: 109, Issue:1-2

    Topics: Animals; Basilar Artery; Calcium; Cerebral Arteries; Dogs; Endothelin-1; Female; In Vitro Techniques

2001
Effects of berbamine on contraction and Ca2+ influx of pig basilar artery.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:5

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Basilar Artery; Benzylisoquinolines; Calcium; Muscle Con

1992
In vivo potentiation of atracurium neuromuscular blockade by nimodipine in rabbits.
    Acta anaesthesiologica Scandinavica, 1992, Volume: 36, Issue:1

    Topics: Animals; Atracurium; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Muscle Con

1992
Relaxant effects on iloprost in canine cerebral artery.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:5

    Topics: Animals; Basilar Artery; Cerebral Arteries; Dogs; Female; Iloprost; In Vitro Techniques; Male; Muscl

1992
Functional effects, binding sites and immunolocalization of endothelin-1 in isolated penile tissues from man and rabbit.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:2

    Topics: Adolescent; Adult; Aged; Animals; Autoradiography; Binding Sites; Culture Techniques; Endothelins; H

1992
Increased calcium sensitivity in isolated resistance arteries from spontaneously hypertensive rats: effects of dihydropyridines.
    European journal of pharmacology, 1990, Apr-25, Volume: 179, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
AHR-16303B, a novel antagonist of 5-HT2 receptors and voltage-sensitive calcium channels.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:1

    Topics: Animals; Atrial Function; Blood Pressure; Calcium; Calcium Channel Blockers; Calcium Channels; Calci

1991
Calcium antagonistic properties of the sesquiterpene T-cadinol: a comparison with nimodipine in the isolated rat aorta.
    Pharmacology & toxicology, 1991, Volume: 69, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Antagonistic effects of dihydropyridines and verapamil on CaCl2 and 5-HT-evoked contraction in porcine coronary artery.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991, Volume: 12, Issue:5

    Topics: Animals; Calcium Chloride; Coronary Vessels; Dihydropyridines; Felodipine; In Vitro Techniques; Musc

1991
Effect of clonidine, nimodipine and diltiazem on the in vitro opioid withdrawal response in the guinea-pig ileum.
    British journal of pharmacology, 1990, Volume: 101, Issue:4

    Topics: Animals; Clonidine; Diltiazem; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Morphi

1990
[Effect of nimodipine on the contraction and the Ca influx of rat aorta].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:4

    Topics: Animals; Aorta; Biological Transport, Active; Calcium; Male; Muscle Contraction; Muscle, Smooth, Vas

1990
Effects of Ca2+ entry blockers on CaCl2-, KCl- and noradrenaline-induced contractions of goat cerebral arteries.
    European journal of pharmacology, 1990, Feb-20, Volume: 177, Issue:1-2

    Topics: Animals; Calcium Channel Blockers; Calcium Chloride; Cerebral Arteries; Egtazic Acid; Female; Goats;

1990
Changes in contractile response and effect of a calcium antagonist, nimodipine, in isolated intracranial arteries of baboon following experimental subarachnoid hemorrhage.
    Brain research bulletin, 1990, Volume: 24, Issue:3

    Topics: Animals; Calcium Channel Blockers; Cerebral Arteries; Female; In Vitro Techniques; Male; Muscle Cont

1990
Comparison of intraluminally versus extraluminally administered nimodipine on serotonin-induced cerebral vascular responses in vitro and in situ.
    Stroke, 1989, Volume: 20, Issue:8

    Topics: Animals; Cats; Cattle; Cerebral Arteries; Cerebrovascular Circulation; Endothelium, Vascular; In Vit

1989
Ca2+ channel antagonist actions in bladder smooth muscle: comparative pharmacologic and [3H]nitrendipine binding studies.
    Canadian journal of physiology and pharmacology, 1985, Volume: 63, Issue:5

    Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Diltiazem; Gallopamil; Guinea Pigs; In

1985
Actions of some vasodilators on isolated human hand veins.
    Acta physiologica Scandinavica, 1987, Volume: 130, Issue:4

    Topics: Adolescent; Adult; Aged; Dinoprost; Female; Hand; Humans; Lidocaine; Male; Middle Aged; Muscle Contr

1987
Effects of the new calcium antagonist 2-nitratopropyl-3-nitratopropyl-2,6-dimethyl-4-(3-nitrophe nyl)- 1,4-dihydropyridine-3,5-dicarboxylate on cerebral circulation in dogs.
    Arzneimittel-Forschung, 1987, Volume: 37, Issue:11

    Topics: Animals; Basilar Artery; Calcium Channel Blockers; Cerebrovascular Circulation; Dihydropyridines; Di

1987
Sources of activator calcium for extrinsic vascular tone and nimodipine inhibition of that tone in proximal vs. distal rabbit ear arteries.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:1

    Topics: Animals; Arteries; Calcium; Ear; Female; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Mu

1987
Cellular actions and pharmacology of calcium-channel blockers.
    The American journal of emergency medicine, 1985, Volume: 3, Issue:6 Suppl

    Topics: Actins; Action Potentials; Calcium; Calcium Channel Blockers; Cell Membrane; Drug Interactions; Extr

1985