nimodipine has been researched along with Motor Neuron Disease in 1 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
Motor Neuron Disease: Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Disease progression was assessed by repeated computerized measurements of isometric force from 20 muscle groups, and calculation of global force score." | 6.67 | Can nimodipine affect progression of motor neuron disease? A double-blind pilot study. ( Abraham, M; Achiron, A; Djaldetti, R; Melamed, E; Ziv, I, 1994) |
| "Disease progression was assessed by repeated computerized measurements of isometric force from 20 muscle groups, and calculation of global force score." | 2.67 | Can nimodipine affect progression of motor neuron disease? A double-blind pilot study. ( Abraham, M; Achiron, A; Djaldetti, R; Melamed, E; Ziv, I, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ziv, I | 1 |
| Achiron, A | 1 |
| Djaldetti, R | 1 |
| Abraham, M | 1 |
| Melamed, E | 1 |
1 trial available for nimodipine and Motor Neuron Disease
| Article | Year |
|---|---|
Can nimodipine affect progression of motor neuron disease? A double-blind pilot study.
Topics: Administration, Oral; Calcium Channel Blockers; Cross-Over Studies; Disease Progression; Double-Blin | 1994 |