nimodipine has been researched along with Morphine Abuse in 8 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of chronic administration of dihydropyridine calcium channel antagonist nimodipine (1 mg/kg/day) given concurrently with morphine on the signs of morphine withdrawal and on the [3H]nitrendipine binding in the rat brain has been investigated." | 1.29 | Concurrent nimodipine attenuates the withdrawal signs and the increase of cerebral dihydropyridine binding after chronic morphine treatment in rats. ( Ahtee, L; Moisio, J; Tötterman, AM; Zharkovsky, A, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, CY | 1 |
| Mo, ZX | 1 |
| Tu, HH | 1 |
| Martínez, MD | 1 |
| Milanés, MV | 1 |
| Laorden, ML | 1 |
| Colado, MI | 2 |
| Alfaro, MJ | 2 |
| Lopez, F | 2 |
| Del Val, V | 1 |
| Martin, MI | 2 |
| Zharkovsky, A | 1 |
| Tötterman, AM | 1 |
| Moisio, J | 1 |
| Ahtee, L | 1 |
| Liu, ZH | 1 |
| Li, JL | 1 |
| Li, N | 1 |
| Tian, CL | 1 |
| Zhang, KG | 1 |
| Ramkumar, V | 1 |
| el-Fakahany, EE | 1 |
| Bongianni, F | 1 |
| Carla, V | 1 |
| Moroni, F | 1 |
| Pellegrini-Giampietro, DE | 1 |
8 other studies available for nimodipine and Morphine Abuse
| Article | Year |
|---|---|
Effect of sinomenine on morphine dependence in isolated guinea pig ileum.
Topics: Animals; Guinea Pigs; Ileum; Morphinans; Morphine; Morphine Dependence; Muscle Contraction; Naloxone | 2003 |
Implication of the signal transduction pathways in the enhancement of noradrenaline turnover induced by morphine withdrawal in the heart.
Topics: Animals; Calcium Channels, L-Type; Calcium Signaling; Cyclic AMP-Dependent Protein Kinases; Drug Com | 2003 |
Effect of nimodipine, diltiazem and BAY K 8644 on the behavioural and neurochemical changes associated with naloxone-precipitated withdrawal in the rat. A comparison with clonidine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1993 |
Concurrent nimodipine attenuates the withdrawal signs and the increase of cerebral dihydropyridine binding after chronic morphine treatment in rats.
Topics: Animals; Brain; Dihydropyridines; Male; Morphine; Morphine Dependence; Motor Activity; Nimodipine; R | 1993 |
Effect of tetrandrine on morphine dependence in isolated guinea pig ileum.
Topics: Alkaloids; Animals; Benzylisoquinolines; Calcium Channel Blockers; Guinea Pigs; Ileum; In Vitro Tech | 1999 |
Effect of clonidine, nimodipine and diltiazem on the in vitro opioid withdrawal response in the guinea-pig ileum.
Topics: Animals; Clonidine; Diltiazem; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Morphi | 1990 |
Prolonged morphine treatment increases rat brain dihydropyridine binding sites: possible involvement in development of morphine dependence.
Topics: Analgesics; Animals; Behavior, Animal; Brain; Calcium Channels; Dihydropyridines; Male; Mice; Morphi | 1988 |
Calcium channel inhibitors suppress the morphine-withdrawal syndrome in rats.
Topics: Animals; Behavior, Animal; Brain Chemistry; Calcium Channel Blockers; Methoxyhydroxyphenylglycol; Mo | 1986 |