nimodipine has been researched along with Metabolic Acidosis in 7 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We have previously constructed chitosan nanoparticles as drug carriers, which release nimodipine in response to decreasing pH typical of cerebral ischemia." | 7.96 | Chitosan nanoparticles release nimodipine in response to tissue acidosis to attenuate spreading depolarization evoked during forebrain ischemia. ( Bari, F; Dékány, I; Farkas, E; Hantosi, D; Ivánkovits-Kiss, O; Janovák, L; Menyhárt, Á; Szabó, Í; Tóth, OM; Varga, DP; Varga, VÉ, 2020) |
| "Nimodipine-treated rats received the drug as an intravenous infusion of 0." | 5.28 | Nimodipine prevents hyperglycemia-induced cerebral acidosis in middle cerebral artery occluded rats. ( Berger, L; Hakim, AM, 1989) |
| " We have previously constructed chitosan nanoparticles as drug carriers, which release nimodipine in response to decreasing pH typical of cerebral ischemia." | 3.96 | Chitosan nanoparticles release nimodipine in response to tissue acidosis to attenuate spreading depolarization evoked during forebrain ischemia. ( Bari, F; Dékány, I; Farkas, E; Hantosi, D; Ivánkovits-Kiss, O; Janovák, L; Menyhárt, Á; Szabó, Í; Tóth, OM; Varga, DP; Varga, VÉ, 2020) |
| "Nimodipine-treated rats received the drug as an intravenous infusion of 0." | 1.28 | Nimodipine prevents hyperglycemia-induced cerebral acidosis in middle cerebral artery occluded rats. ( Berger, L; Hakim, AM, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Tóth, OM | 1 |
| Menyhárt, Á | 1 |
| Varga, VÉ | 1 |
| Hantosi, D | 1 |
| Ivánkovits-Kiss, O | 1 |
| Varga, DP | 1 |
| Szabó, Í | 1 |
| Janovák, L | 2 |
| Dékány, I | 2 |
| Farkas, E | 2 |
| Bari, F | 2 |
| Turcsányi, Á | 1 |
| Bozó, É | 1 |
| Deák, Á | 1 |
| Mérai, L | 1 |
| Sebők, D | 1 |
| Juhász, Á | 1 |
| Csapó, E | 1 |
| Abdelghafour, MM | 1 |
| Lemons, V | 1 |
| Chehrazi, BB | 1 |
| Kauten, R | 1 |
| Hein, L | 1 |
| Wagner, FC | 1 |
| Hakin, AM | 1 |
| Berger, L | 2 |
| Hakim, AM | 3 |
1 review available for nimodipine and Metabolic Acidosis
| Article | Year |
|---|---|
Hemodynamic and metabolic studies in stroke.
Topics: Acidosis; Brain; Brain Ischemia; Cerebral Infarction; Cerebral Revascularization; Cerebrovascular Di | 1989 |
1 trial available for nimodipine and Metabolic Acidosis
| Article | Year |
|---|---|
Hemodynamic and metabolic studies in stroke.
Topics: Acidosis; Brain; Brain Ischemia; Cerebral Infarction; Cerebral Revascularization; Cerebrovascular Di | 1989 |
6 other studies available for nimodipine and Metabolic Acidosis
| Article | Year |
|---|---|
Chitosan nanoparticles release nimodipine in response to tissue acidosis to attenuate spreading depolarization evoked during forebrain ischemia.
Topics: Acidosis; Animals; Biocompatible Materials; Brain Ischemia; Calcium Channel Blockers; Carotid Artery | 2020 |
Preparation of novel tissue acidosis-responsive chitosan drug nanoparticles: Characterization and in vitro release properties of Ca
Topics: Acidosis; Calcium Channel Blockers; Chitosan; Drug Carriers; Drug Liberation; Humans; Nanoparticles; | 2018 |
The effect of nimodipine on high-energy phosphates and intracellular pH during cerebral ischemia.
Topics: Acidosis; Adenosine Triphosphate; Animals; Brain Ischemia; Carotid Artery, Common; Energy Metabolism | 1993 |
Nimodipine prevents hyperglycemia-induced cerebral acidosis in middle cerebral artery occluded rats.
Topics: Acidosis; Animals; Brain Diseases; Brain Ischemia; Cerebrovascular Circulation; Hydrogen-Ion Concent | 1989 |
Calcium channel blockers correct acidosis in ischemic rat brain without altering cerebral blood flow.
Topics: Acidosis; Animals; Brain; Brain Ischemia; Calcium Channel Blockers; Cerebrovascular Circulation; Epo | 1988 |
Cerebral acidosis in focal ischemia: II. Nimodipine and verapamil normalize cerebral pH following middle cerebral artery occlusion in the rat.
Topics: Acidosis; Animals; Arterial Occlusive Diseases; Brain; Brain Diseases; Brain Ischemia; Calcium Chann | 1986 |