nimodipine has been researched along with Memory Disorders in 18 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
Memory Disorders: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nimodipine given 7-14 days after cerebral infarction for 3 months results in memory improvement." | 9.08 | Effect of nimodipine on memory after cerebral infarction. ( Cheng, S; Sim, TC; Sze, KH; Wong, E; Woo, J, 1998) |
| "Nimodipine given 7-14 days after cerebral infarction for 3 months results in memory improvement." | 5.08 | Effect of nimodipine on memory after cerebral infarction. ( Cheng, S; Sim, TC; Sze, KH; Wong, E; Woo, J, 1998) |
| "LPS-infused rats had significant memory deficits in the Morris water maze, and this deficit was ameliorated by treatment with nimodipine." | 1.42 | Calcium dysregulation via L-type voltage-dependent calcium channels and ryanodine receptors underlies memory deficits and synaptic dysfunction during chronic neuroinflammation. ( Adzovic, L; Crockett, AM; D'Angelo, HM; Hopp, SC; Kaercher, RM; Royer, SE; Wenk, GL, 2015) |
| "Nimodipine in both treatment forms prevented the memory impairment following spontaneous morphine withdrawal." | 1.38 | The effect of nimodipine on memory impairment during spontaneous morphine withdrawal in mice: Corticosterone interaction. ( Hajhashemi, V; Rabbani, M; Vaseghi, G, 2012) |
| "Both nimodipine treatments prevented the memory deficits when these were measured between 1 and 2 months after alcohol withdrawal." | 1.35 | Nimodipine prior to alcohol withdrawal prevents memory deficits during the abstinence phase. ( Brooks, SP; Croft, AP; Little, HJ; Norman, G; Shaw, SG, 2008) |
| "NMD reversed the long-term memory loss induced by PHT and VPA in the PAT." | 1.30 | Effect of nimodipine on the cognitive dysfunction induced by phenytoin and valproate in rats. ( Balakrishnan, S; Pandhi, P, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (38.89) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 7 (38.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y | 2 |
| Guo, Z | 1 |
| Peng, X | 1 |
| Xie, W | 1 |
| Chen, L | 1 |
| Tan, Z | 1 |
| Yan, B | 1 |
| Sun, Y | 1 |
| Zeng, J | 1 |
| Li, C | 1 |
| Song, P | 1 |
| Zhang, L | 1 |
| Yang, X | 1 |
| Wu, Y | 1 |
| Ma, P | 1 |
| Hopp, SC | 2 |
| D'Angelo, HM | 2 |
| Royer, SE | 2 |
| Kaercher, RM | 2 |
| Adzovic, L | 2 |
| Wenk, GL | 2 |
| Crockett, AM | 1 |
| Brooks, SP | 1 |
| Croft, AP | 1 |
| Norman, G | 1 |
| Shaw, SG | 1 |
| Little, HJ | 1 |
| Bekker, A | 1 |
| Haile, M | 1 |
| Li, YS | 1 |
| Galoyan, S | 1 |
| Garcia, E | 1 |
| Quartermain, D | 1 |
| Kamer, A | 1 |
| Blanck, T | 1 |
| Vaseghi, G | 1 |
| Rabbani, M | 1 |
| Hajhashemi, V | 1 |
| Gholamipour-Badie, H | 1 |
| Naderi, N | 1 |
| Khodagholi, F | 1 |
| Shaerzadeh, F | 1 |
| Motamedi, F | 1 |
| Corradini, I | 1 |
| Donzelli, A | 1 |
| Antonucci, F | 1 |
| Welzl, H | 1 |
| Loos, M | 1 |
| Martucci, R | 1 |
| De Astis, S | 1 |
| Pattini, L | 1 |
| Inverardi, F | 1 |
| Wolfer, D | 1 |
| Caleo, M | 1 |
| Bozzi, Y | 1 |
| Verderio, C | 1 |
| Frassoni, C | 1 |
| Braida, D | 1 |
| Clerici, M | 1 |
| Lipp, HP | 1 |
| Sala, M | 1 |
| Matteoli, M | 1 |
| Veng, LM | 1 |
| Mesches, MH | 1 |
| Browning, MD | 1 |
| Zhang, G | 1 |
| Liu, A | 1 |
| Zhou, Y | 1 |
| San, X | 1 |
| Jin, T | 1 |
| Jin, Y | 1 |
| Hütter, BO | 1 |
| Gilsbach, JM | 1 |
| Balakrishnan, S | 1 |
| Pandhi, P | 1 |
| Paróczai, M | 1 |
| Kiss, B | 1 |
| Kárpáti, E | 1 |
| Sze, KH | 1 |
| Sim, TC | 1 |
| Wong, E | 1 |
| Cheng, S | 1 |
| Woo, J | 1 |
| Sui, J | 1 |
| Xiong, Y | 1 |
| Zhang, C | 1 |
| Xu, WX | 1 |
| Guo, YP | 1 |
| Zhao, F | 1 |
2 trials available for nimodipine and Memory Disorders
| Article | Year |
|---|---|
Effect of nimodipine on memory after cerebral infarction.
Topics: Aged; Aged, 80 and over; Atrial Fibrillation; Calcium Channel Blockers; Cerebral Infarction; Depress | 1998 |
[A clinical study of recovery of memories in 46 cases of cerebrovascular diseases].
Topics: Aged; Cerebral Infarction; Double-Blind Method; Female; Humans; Male; Memory; Memory Disorders; Midd | 1991 |
16 other studies available for nimodipine and Memory Disorders
| Article | Year |
|---|---|
Nimodipine represses AMPK phosphorylation and excessive autophagy after chronic cerebral hypoperfusion in rats.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Brain; Calcium Channel Blockers; Calcium Channels | 2018 |
Combined use of vitamin E and nimodipine ameliorates dibutyl phthalate-induced memory deficit and apoptosis in mice by inhibiting the ERK 1/2 pathway.
Topics: Animals; Antioxidants; Apoptosis; Behavior, Animal; Calcium Channel Blockers; Calcium Signaling; Dib | 2019 |
Differential rescue of spatial memory deficits in aged rats by L-type voltage-dependent calcium channel and ryanodine receptor antagonism.
Topics: Aging; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Dantrolene; Gene Expression; Hip | 2014 |
Calcium dysregulation via L-type voltage-dependent calcium channels and ryanodine receptors underlies memory deficits and synaptic dysfunction during chronic neuroinflammation.
Topics: AIDS-Related Complex; Analysis of Variance; Animals; Calcium; Calcium Channel Blockers; Calcium Chan | 2015 |
Nimodipine prior to alcohol withdrawal prevents memory deficits during the abstinence phase.
Topics: Alcohol-Induced Disorders; Alcohols; Analysis of Variance; Animals; Body Weight; Brain; Calcium Chan | 2008 |
Nimodipine prevents memory impairment caused by nitroglycerin-induced hypotension in adult mice.
Topics: Animals; Avoidance Learning; Behavior, Animal; Blood Pressure; Calcium Channel Blockers; Cerebrovasc | 2009 |
The effect of nimodipine on memory impairment during spontaneous morphine withdrawal in mice: Corticosterone interaction.
Topics: Animals; Brain; Calcium Channel Blockers; Corticosterone; Male; Memory Disorders; Mice; Morphine; Ni | 2012 |
L-type calcium channel blockade alleviates molecular and reversal spatial learning and memory alterations induced by entorhinal amyloid pathology in rats.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Area Under Curve; Calcium Channel Blockers; Ca | 2013 |
Epileptiform activity and cognitive deficits in SNAP-25(+/-) mice are normalized by antiepileptic drugs.
Topics: Animals; Anticonvulsants; Association Learning; Brain; Carbamazepine; Cognition Disorders; Epilepsy; | 2014 |
Age-related working memory impairment is correlated with increases in the L-type calcium channel protein alpha1D (Cav1.3) in area CA1 of the hippocampus and both are ameliorated by chronic nimodipine treatment.
Topics: Aging; Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium-Calmod | 2003 |
Panax ginseng ginsenoside-Rg2 protects memory impairment via anti-apoptosis in a rat model with vascular dementia.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Dementia, Vascular; Disease Models, Animal; Dose-Res | 2008 |
Which neuropsychological deficits are hidden behind a good outcome (Glasgow = I) after aneurysmal subarachnoid hemorrhage?
Topics: Adult; Age Factors; Aphasia; Cognition Disorders; Female; Follow-Up Studies; Glasgow Coma Scale; Hum | 1993 |
Effect of nimodipine on the cognitive dysfunction induced by phenytoin and valproate in rats.
Topics: Animals; Avoidance Learning; Female; Male; Memory Disorders; Nimodipine; Phenytoin; Rats; Retention, | 1997 |
Effect of RGH-2716 on learning and memory deficits of young and aged rats in water-labyrinth.
Topics: Aging; Amnesia, Retrograde; Animals; Diazepam; Learning Disabilities; Male; Maze Learning; Memory; M | 1998 |
[Therapeutic effects of nimodipine on learning and memory of rats with traumatic brain injury].
Topics: Animals; Avoidance Learning; Brain Injuries; Calcium Channel Blockers; Female; Male; Memory Disorder | 1997 |
[Clinical studies on the improvement of failing memory by nimodipine].
Topics: Epinephrine; Female; Humans; Hypertension; Male; Memory Disorders; Middle Aged; Neuropsychological T | 1990 |