Page last updated: 2024-11-01

nimodipine and Ischemic Stroke

nimodipine has been researched along with Ischemic Stroke in 2 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Ischemic Stroke: Stroke due to BRAIN ISCHEMIA resulting in interruption or reduction of blood flow to a part of the brain. When obstruction is due to a BLOOD CLOT formed within in a cerebral blood vessel it is a thrombotic stroke. When obstruction is formed elsewhere and moved to block a cerebral blood vessel (see CEREBRAL EMBOLISM) it is referred to as embolic stroke. Wake-up stroke refers to ischemic stroke occurring during sleep while cryptogenic stroke refers to ischemic stroke of unknown origin.

Research Excerpts

ExcerptRelevanceReference
"Male Sprague-Dawley rats under permanent middle cerebral artery occlusion (pMCAO) model, randomly assigned as: model, sham, nimodipine (0."3.11The therapeutic role of Jingchuan tablet on ischaemic cerebral stroke via the HIF-1α/EPO/VEGFA signalling pathway. ( Fu, Y; Li, D; Liu, Q; Wang, H; Wang, W; Zhang, T; Zhang, Y, 2022)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (100.00)2.80

Authors

AuthorsStudies
Liu, ZJ1
Wang, CP1
Yang, B1
Wang, N1
Wang, Q1
Gu, J1
Tan, R1
Zhang, Y1
Liu, Q1
Zhang, T1
Wang, H1
Fu, Y1
Wang, W1
Li, D1

Trials

1 trial available for nimodipine and Ischemic Stroke

ArticleYear
The therapeutic role of Jingchuan tablet on ischaemic cerebral stroke via the HIF-1α/EPO/VEGFA signalling pathway.
    Pharmaceutical biology, 2022, Volume: 60, Issue:1

    Topics: Animals; Brain Ischemia; Chlorogenic Acid; Disease Models, Animal; Gallic Acid; Infarction, Middle C

2022

Other Studies

1 other study available for nimodipine and Ischemic Stroke

ArticleYear
[Protective effect and mechanism of Ershiwuwei Zhenzhu Pills on cerebral apoplexy rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2022, Volume: 47, Issue:8

    Topics: Animals; Caspase 3; Drugs, Chinese Herbal; Infarction, Middle Cerebral Artery; Interleukin-6; Ischem

2022