nimodipine has been researched along with Ischemia in 16 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The protective effect of the calcium channel blocker nimodipine on liver ischemia and reperfusion was studied in the rat." | 7.69 | Ischemia and reperfusion injury of the rat liver: the role of nimodipine. ( Calne, RY; Chávez-Cartaya, RE; Jamieson, NV; Pino DeSola, G; Ramirez-Romero, P, 1996) |
| "In this study we used two calcium antagonists which have two different modes of action, nimodipine and dantrolene, to prevent NMDA-induced retinal ischemia in guinea pigs." | 3.72 | Calcium antagonists in N-methyl d-aspartate-induced retinal injury. ( Altuntaş, I; Kaya, M; Ozdemir, T; Tunç, M, 2003) |
| "The protective effect of the calcium channel blocker nimodipine on liver ischemia and reperfusion was studied in the rat." | 3.69 | Ischemia and reperfusion injury of the rat liver: the role of nimodipine. ( Calne, RY; Chávez-Cartaya, RE; Jamieson, NV; Pino DeSola, G; Ramirez-Romero, P, 1996) |
| "The purpose of this study is to determine the effects of ischemia in the spinal cord when a calcium channel blocker, nimodipine, is administered intravenously before, during, and after crossclamping of the thoracic aorta." | 3.68 | Spinal cord protection with intravenous nimodipine. A functional and morphologic evaluation. ( Bennink, GB; Cooley, DA; Langford, LA; Schittek, A, 1992) |
| " In cell cultures, CgTx inhibited hypoxia-induced 45Ca accumulation and neuronal injury minimally, compared to the NMDA antagonist ketamine." | 3.68 | Treatment with conotoxin, an 'N-type' calcium channel blocker, in neuronal hypoxic-ischemic injury. ( Clark, WM; Madden, KP; Marcoux, FW; Probert, AW; Rivier, J; Weber, ML; Zivin, JA, 1990) |
| " We report herein the influence of nimodipine, a selective central nervous system calcium channel blocker, in 60 rabbits with seizures that had been induced through ischemia, postischemia reperfusion, pentylenetetrazol, and bicuculline." | 3.67 | Selective central nervous system calcium channel blockers--a new class of anticonvulsant agents. ( Anderson, RE; Meyer, FB; Sharbrough, FW; Sundt, TM, 1986) |
| "Ocular ischaemic syndrome is a progressive and serious vision-threatening condition that is usually associated with carotid artery disease, and poor effective therapeutic options are available." | 1.42 | Reversed ocular ischaemic syndrome secondary to carotid cavernous sinus embolisation. ( Branco, G; Costa, JM; Isidro, F; Reizinho, C, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (37.50) | 18.7374 |
| 1990's | 7 (43.75) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Isidro, F | 1 |
| Reizinho, C | 1 |
| Branco, G | 1 |
| Costa, JM | 1 |
| Kaya, M | 1 |
| Tunç, M | 1 |
| Ozdemir, T | 1 |
| Altuntaş, I | 1 |
| Bischoff, B | 1 |
| Romstöck, J | 1 |
| Fahlbusch, R | 1 |
| Buchfelder, M | 1 |
| Strauss, C | 1 |
| Tator, CH | 3 |
| Faden, AI | 1 |
| Jacobs, TP | 1 |
| Smith, MT | 1 |
| Pointillart, V | 1 |
| Petitjean, ME | 1 |
| Senegas, J | 1 |
| Chávez-Cartaya, RE | 1 |
| Pino DeSola, G | 1 |
| Ramirez-Romero, P | 1 |
| Calne, RY | 1 |
| Jamieson, NV | 1 |
| Raju, TN | 1 |
| John, E | 1 |
| Shankararao, R | 1 |
| Fornell, L | 1 |
| Vasa, R | 1 |
| Abu-Harb, M | 1 |
| Schittek, A | 1 |
| Bennink, GB | 1 |
| Cooley, DA | 1 |
| Langford, LA | 1 |
| Haun, SE | 1 |
| Murphy, EJ | 1 |
| Bates, CM | 1 |
| Horrocks, LA | 1 |
| Zochodne, DW | 1 |
| Ho, LT | 1 |
| Gross, PM | 1 |
| Madden, KP | 1 |
| Clark, WM | 1 |
| Marcoux, FW | 1 |
| Probert, AW | 1 |
| Weber, ML | 1 |
| Rivier, J | 1 |
| Zivin, JA | 1 |
| Wauquier, A | 1 |
| Melis, W | 1 |
| Janssen, PA | 1 |
| Guha, A | 2 |
| Smith, CR | 1 |
| Piper, I | 2 |
| Meyer, FB | 1 |
| Anderson, RE | 1 |
| Sundt, TM | 1 |
| Sharbrough, FW | 1 |
16 other studies available for nimodipine and Ischemia
| Article | Year |
|---|---|
Reversed ocular ischaemic syndrome secondary to carotid cavernous sinus embolisation.
Topics: Aged; Carotid Arteries; Carotid-Cavernous Sinus Fistula; Cavernous Sinus; Embolization, Therapeutic; | 2015 |
Calcium antagonists in N-methyl d-aspartate-induced retinal injury.
Topics: Animals; Calcium Channel Blockers; Cell Count; Dantrolene; Drug Therapy, Combination; Excitatory Ami | 2003 |
Intraoperative brainstem auditory evoked potential pattern and perioperative vasoactive treatment for hearing preservation in vestibular schwannoma surgery.
Topics: Adult; Brain Stem; Cochlear Nerve; Deafness; Evoked Potentials, Auditory, Brain Stem; Female; Follow | 2008 |
Nimodipine in experimental ischemia.
Topics: Animals; Ischemia; Nicotinic Acids; Nimodipine; Spinal Cord | 1984 |
Evaluation of the calcium channel antagonist nimodipine in experimental spinal cord ischemia.
Topics: Animals; Calcium Channel Blockers; Ischemia; Male; Models, Biological; Nicotinic Acids; Nimodipine; | 1984 |
[Bases for drug therapy of spinal cord injuries].
Topics: Female; Humans; Ischemia; Male; Methylprednisolone; Nimodipine; Spinal Cord; Spinal Cord Injuries | 1994 |
Ischemia and reperfusion injury of the rat liver: the role of nimodipine.
Topics: Animals; Calcium Channel Blockers; Hemoglobins; Ischemia; Liver; Liver Circulation; Male; Microcircu | 1996 |
Effect of nimodipine on systemic, renal, and cerebral haemodynamics after a mild hypoxic-ischaemic insult in newborn piglets.
Topics: Animals; Animals, Newborn; Brain; Calcium Channel Blockers; Female; Hemodynamics; Hypoxia; Ischemia; | 1996 |
Spinal cord protection with intravenous nimodipine. A functional and morphologic evaluation.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Cerebrospinal Fluid Pressure; Constriction; Heart Rate; In | 1992 |
Extracellular calcium is a mediator of astroglial injury during combined glucose-oxygen deprivation.
Topics: Animals; Animals, Newborn; Astrocytes; Calcium; Cell Differentiation; Cell Hypoxia; Cells, Cultured; | 1992 |
Acute endoneurial ischemia induced by epineurial endothelin in the rat sciatic nerve.
Topics: Action Potentials; Acute Disease; Animals; Endothelins; Ischemia; Male; Neural Conduction; Nimodipin | 1992 |
Treatment with conotoxin, an 'N-type' calcium channel blocker, in neuronal hypoxic-ischemic injury.
Topics: Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Hypoxia; Injections; Ischemia; Ketamine | 1990 |
Long-term neurological assessment of the post-resuscitative effects of flunarizine, verapamil and nimodipine in a new model of global complete ischaemia.
Topics: Anesthesia; Animals; Behavior, Animal; Disease Models, Animal; Electroencephalography; Electromyogra | 1989 |
Improvement in post-traumatic spinal cord blood flow with a combination of a calcium channel blocker and a vasopressor.
Topics: Animals; Blood Pressure; Drug Therapy, Combination; Epinephrine; Hematocrit; Ischemia; Male; Nimodip | 1989 |
Effect of a calcium channel blocker on posttraumatic spinal cord blood flow.
Topics: Angiotensin II; Animals; Blood Physiological Phenomena; Blood Pressure; Ischemia; Male; Nimodipine; | 1987 |
Selective central nervous system calcium channel blockers--a new class of anticonvulsant agents.
Topics: Animals; Anticonvulsants; Bicuculline; Calcium Channel Blockers; Central Nervous System; Convulsants | 1986 |