nimodipine has been researched along with Innate Inflammatory Response in 8 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with nimodipine reduced the degeneration of dopaminergic (DA) neurons induced by LPS in mesencephalic neuron-glia cultures in a dose-dependent manner." | 5.35 | Nimodipine protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation. ( An, L; Bao, Y; Hu, X; Li, Y; Liu, Y, 2009) |
| "Pretreatment with nimodipine reduced the degeneration of dopaminergic (DA) neurons induced by LPS in mesencephalic neuron-glia cultures in a dose-dependent manner." | 1.35 | Nimodipine protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation. ( An, L; Bao, Y; Hu, X; Li, Y; Liu, Y, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Zamora, NN | 1 |
| Cheli, VT | 1 |
| Santiago González, DA | 1 |
| Wan, R | 1 |
| Paez, PM | 1 |
| Chen, X | 1 |
| Yao, Z | 1 |
| Peng, X | 1 |
| Wu, L | 1 |
| Wu, H | 1 |
| Ou, Y | 1 |
| Lai, J | 1 |
| Li, Y | 1 |
| Hu, X | 1 |
| Liu, Y | 1 |
| Bao, Y | 1 |
| An, L | 1 |
| Soliman, GM | 1 |
| Sharma, R | 1 |
| Choi, AO | 1 |
| Varshney, SK | 1 |
| Winnik, FM | 1 |
| Kakkar, AK | 1 |
| Maysinger, D | 1 |
| Zhang, XL | 1 |
| Zheng, SL | 1 |
| Dong, FR | 1 |
| Wang, ZM | 1 |
| Tubbs, RS | 1 |
| Shoja, MM | 1 |
| Jamshidi, M | 1 |
| Shokouhi, G | 1 |
| Neugebauer, V | 1 |
| Vanegas, H | 1 |
| Nebe, J | 1 |
| Rümenapp, P | 1 |
| Schaible, HG | 1 |
8 other studies available for nimodipine and Innate Inflammatory Response
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Deletion of Voltage-Gated Calcium Channels in Astrocytes during Demyelination Reduces Brain Inflammation and Promotes Myelin Regeneration in Mice.
Topics: Animals; Astrocytes; Brain; Calcium Channel Blockers; Calcium Channels; Cuprizone; Demyelinating Dis | 2020 |
Eupafolin alleviates cerebral ischemia/reperfusion injury in rats via blocking the TLR4/NF‑κB signaling pathway.
Topics: Animals; Apoptosis; Brain Ischemia; China; Flavones; Infarction, Middle Cerebral Artery; Inflammatio | 2020 |
Nimodipine protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation.
Topics: Animals; Cell Culture Techniques; Dopamine; Inflammation; Lipopolysaccharides; Mice; Microglia; NADP | 2009 |
Tailoring the efficacy of nimodipine drug delivery using nanocarriers based on A2B miktoarm star polymers.
Topics: Animals; Anti-Inflammatory Agents; Calcium Channel Blockers; Cell Line; Cell Survival; Cytokines; Dr | 2010 |
Nimodipine improves regional cerebral blood flow and suppresses inflammatory factors in the hippocampus of rats with vascular dementia.
Topics: Animals; Calcium Channel Blockers; Cerebrovascular Circulation; Dementia, Vascular; Hippocampus; Imm | 2012 |
Does the neuroprotective agent erythropoietin amplify diffuse axonal injury in its early stages?
Topics: Animals; Axons; Brain; Calcium; Calcium Channels; Cell Proliferation; Diffuse Axonal Injury; Erythro | 2007 |
Effects of N- and L-type calcium channel antagonists on the responses of nociceptive spinal cord neurons to mechanical stimulation of the normal and the inflamed knee joint.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1996 |