nimodipine has been researched along with Injuries, Spinal Cord in 32 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of nimodipine and thyrotropin-releasing hormone (TRH) were compared in a clip-compression model of experimental spinal cord injuries (SCI) in rats." | 7.68 | Treatment of acute spinal cord injuries: comparison of thyrotropin-releasing hormone and nimodipine. ( Aktürk, F; Baykal, S; Ceylan, S; Ilbay, K; Kalelioğlu, M; Komsuoğlu, SS; Ozmenoğlu, M; Ozoran, A; Sener, U, 1992) |
| " Pretreatment with p-chlorophenylalanine, indomethacin, ibuprofen, and nimodipine attenuated the SCEP changes immediately after trauma and resulted in a marked reduction in edema formation, BSCB permeability, and blood flow changes at 5 h." | 3.71 | Assessment of spinal cord pathology following trauma using early changes in the spinal cord evoked potentials: a pharmacological and morphological study in the rat. ( Sharma, HS; Winkler, T, 2002) |
| "The effects of nimodipine and thyrotropin-releasing hormone (TRH) were compared in a clip-compression model of experimental spinal cord injuries (SCI) in rats." | 3.68 | Treatment of acute spinal cord injuries: comparison of thyrotropin-releasing hormone and nimodipine. ( Aktürk, F; Baykal, S; Ceylan, S; Ilbay, K; Kalelioğlu, M; Komsuoğlu, SS; Ozmenoğlu, M; Ozoran, A; Sener, U, 1992) |
| "Nimodipine treatment could reduce oxidative injury after spinal cord injury, reduce the whole dead space and inflammation, and repair spinal cord injury." | 1.42 | Effect of nimodipine on rat spinal cord injury. ( Gao, HL; Jia, YF; Li, J; Ma, LJ, 2015) |
| "[3H]Nimodipine was administered 5 min after laminectomy in the control group, and at the above-specified times after injury in the SCI groups." | 1.30 | Autoradiographic [3H]nimodipine distribution after experimental spinal cord injury in rats. ( Koyanagi, I; Ross, IB; Tator, CH; Wallace, MC, 1999) |
| "Nimodipine was infused i." | 1.28 | Spinal cord injury in rats: inability of nimodipine or anti-neutrophil serum to improve spinal cord blood flow or neurologic status. ( Gerdin, B; Holtz, A; Nyström, B, 1989) |
| "The effect of nimodipine on acute spinal cord trauma was studied in cats." | 1.27 | Effect of nimodipine-associated hypotension on recovery from acute spinal cord injury in cats. ( Chehrazi, BB; Haghighi, SS; Wagner, FC, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (18.75) | 18.7374 |
| 1990's | 16 (50.00) | 18.2507 |
| 2000's | 5 (15.63) | 29.6817 |
| 2010's | 4 (12.50) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Marcantoni, M | 1 |
| Fuchs, A | 1 |
| Löw, P | 1 |
| Bartsch, D | 1 |
| Kiehn, O | 1 |
| Bellardita, C | 1 |
| Jia, YF | 1 |
| Gao, HL | 1 |
| Ma, LJ | 1 |
| Li, J | 1 |
| Sun, W | 1 |
| Fu, Y | 1 |
| Shi, Y | 1 |
| Cheng, JX | 1 |
| Cao, P | 1 |
| Shi, R | 2 |
| Bracken, MB | 1 |
| Tator, CH | 9 |
| Hashimoto, R | 1 |
| Raich, A | 1 |
| Norvell, D | 1 |
| Fehlings, MG | 2 |
| Harrop, JS | 1 |
| Guest, J | 1 |
| Aarabi, B | 1 |
| Grossman, RG | 1 |
| Sharma, HS | 2 |
| Winkler, T | 3 |
| Stålberg, E | 1 |
| Badgaiyan, RD | 1 |
| Gordh, T | 1 |
| Westman, J | 1 |
| Nehrt, A | 1 |
| Rodgers, R | 1 |
| Shapiro, S | 1 |
| Borgens, R | 1 |
| Trembly, B | 1 |
| Pointillard, V | 1 |
| Petitjean, ME | 5 |
| Pointillart, V | 5 |
| Senegas, J | 2 |
| Ross, IB | 4 |
| Theriault, E | 1 |
| Gense, D | 1 |
| Gross, C | 1 |
| Bidabé, AM | 1 |
| Gin, AM | 1 |
| Rivel, J | 1 |
| Caillé, JM | 1 |
| Haghighi, SS | 2 |
| Stiens, T | 1 |
| Oro, JJ | 1 |
| Madsen, R | 1 |
| Gambardella, G | 1 |
| Collufio, D | 1 |
| Caruso, GN | 1 |
| Abbate, F | 1 |
| Germanà, G | 1 |
| Tomasello, F | 1 |
| Imamura, H | 1 |
| Dixmerias, F | 1 |
| Wiart, L | 2 |
| Sztark, F | 1 |
| Lassié, P | 2 |
| Thicoïpé, M | 2 |
| Dabadie, P | 2 |
| Kaynar, MY | 1 |
| Erdinçler, P | 1 |
| Tadayyon, E | 1 |
| Belce, A | 1 |
| Gümüstas, K | 1 |
| Ciplak, N | 1 |
| Koyanagi, I | 1 |
| Wallace, MC | 1 |
| Vital, JM | 1 |
| Deng, SL | 1 |
| Yuan, T | 1 |
| Liao, WH | 1 |
| Ceylan, S | 2 |
| Ilbay, K | 1 |
| Baykal, S | 1 |
| Sener, U | 1 |
| Ozmenoğlu, M | 1 |
| Kalelioğlu, M | 1 |
| Aktürk, F | 1 |
| Komsuoğlu, SS | 1 |
| Ozoran, A | 1 |
| Linden, RD | 1 |
| Holtz, A | 1 |
| Nyström, B | 1 |
| Gerdin, B | 1 |
| Guha, A | 2 |
| Smith, CR | 1 |
| Piper, I | 2 |
| Chehrazi, BB | 1 |
| Wagner, FC | 1 |
| Ford, RW | 1 |
| Malm, DN | 1 |
3 reviews available for nimodipine and Injuries, Spinal Cord
| Article | Year |
|---|---|
Steroids for acute spinal cord injury.
Topics: Anti-Inflammatory Agents; Drug Administration Schedule; Glucocorticoids; Humans; Methylprednisolone; | 2012 |
Translational potential of preclinical trials of neuroprotection through pharmacotherapy for spinal cord injury.
Topics: Animals; Disease Models, Animal; Glyburide; Humans; Magnesium Sulfate; Minocycline; Neuroprotective | 2012 |
Clinical potential for the use of neuroprotective agents. A brief overview.
Topics: Animals; Brain Diseases; Brain Injuries; Brain Ischemia; Calcium Channel Blockers; Cerebrovascular D | 1995 |
2 trials available for nimodipine and Injuries, Spinal Cord
| Article | Year |
|---|---|
[Medical treatment of spinal cord injury in the acute stage].
Topics: Acute Disease; Adolescent; Adult; Anti-Inflammatory Agents; Calcium Channel Blockers; Female; Follow | 1998 |
Pharmacological therapy of spinal cord injury during the acute phase.
Topics: Acute Disease; Adult; Calcium Channel Blockers; Drug Therapy, Combination; Humans; Infections; Methy | 2000 |
27 other studies available for nimodipine and Injuries, Spinal Cord
| Article | Year |
|---|---|
Early delivery and prolonged treatment with nimodipine prevents the development of spasticity after spinal cord injury in mice.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Mice; Muscle Spasticity; Nimodipine; Qu | 2020 |
Effect of nimodipine on rat spinal cord injury.
Topics: Animals; Calcium Channel Blockers; Free Radicals; Immunohistochemistry; Macrophages; Male; Malondial | 2015 |
Paranodal myelin damage after acute stretch in Guinea pig spinal cord.
Topics: 4-Aminopyridine; Action Potentials; Animals; Biotransformation; Calcium; Calcium Channel Blockers; C | 2012 |
Assessment of spinal cord pathology following trauma using early changes in the spinal cord evoked potentials: a pharmacological and morphological study in the rat.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Anti-I | 2002 |
An L-type calcium channel blocker, nimodipine influences trauma induced spinal cord conduction and axonal injury in the rat.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Diffuse Axonal Injury; Edema; Evoked Po | 2003 |
The critical role of voltage-dependent calcium channel in axonal repair following mechanical trauma.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2007 |
[Medical treatment of spinal cord injury during the acute phase. Effect of a calcium inhibitor].
Topics: Animals; Calcium Channel Blockers; Disease Models, Animal; Nimodipine; Papio; Regional Blood Flow; S | 1993 |
[Bases for drug therapy of spinal cord injuries].
Topics: Female; Humans; Ischemia; Male; Methylprednisolone; Nimodipine; Spinal Cord; Spinal Cord Injuries | 1994 |
Possibilities to evaluate and diminish the effects of the trauma in spinal cord lesions. An experimental study in the rat.
Topics: Animals; Disease Models, Animal; Evoked Potentials; Indomethacin; Naloxone; Neural Conduction; Nimod | 1994 |
Effect of nimodipine or methylprednisolone on recovery from acute experimental spinal cord injury in rats.
Topics: Acute Disease; Analysis of Variance; Animals; Cell Count; Evoked Potentials, Somatosensory; Methylpr | 1993 |
Effects of nimodipine on posttraumatic spinal cord ischemia in baboons.
Topics: Animals; Blood Pressure; Evoked Potentials, Somatosensory; Magnetic Resonance Imaging; Nimodipine; P | 1993 |
Spinal cord blood flow and evoked potential responses after treatment with nimodipine or methylprednisolone in spinal cord-injured rats.
Topics: Animals; Blood Flow Velocity; Evoked Potentials; Male; Methylprednisolone; Nimodipine; Rats; Rats, W | 1993 |
Evaluation of the calcium channel antagonist nimodipine after experimental spinal cord injury.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Evoked Potentials, Somatosensory; Nimodipine; Rat | 1993 |
Experimental incomplete spinal cord injury: treatment with a combination of nimodipine and adrenaline.
Topics: Animals; Blood Pressure; Drug Therapy, Combination; Epinephrine; Female; Male; Nimodipine; Rabbits; | 1995 |
Effect of intrathecal nimodipine on spinal cord blood flow and evoked potentials in the normal or injured cord.
Topics: Animals; Blood Pressure; Disease Models, Animal; Evoked Potentials; Injections, Spinal; Male; Nimodi | 1998 |
Effect of nimodipine and N-acetylcysteine on lipid peroxidation after experimental spinal cord injury.
Topics: Acetylcysteine; Animals; Calcium Channel Blockers; Female; Free Radical Scavengers; Lipid Peroxidati | 1998 |
Autoradiographic [3H]nimodipine distribution after experimental spinal cord injury in rats.
Topics: Animals; Autoradiography; Blood Gas Analysis; Blood Pressure; Body Temperature; Body Weight; Calcium | 1999 |
[Effect of fetal spinal cord graft with nerve growth factor and nimodipine in secondary injury of spinal cord of adult rat].
Topics: Animals; Calcium Channel Blockers; Combined Modality Therapy; Female; Fetal Tissue Transplantation; | 2001 |
[Effects of continuous administration of nimodipine during the acute phase of spinal cord injury in baboons].
Topics: Animals; Double-Blind Method; Nimodipine; Papio; Regional Blood Flow; Research Design; Spinal Cord; | 1992 |
Treatment of acute spinal cord injuries: comparison of thyrotropin-releasing hormone and nimodipine.
Topics: Animals; Blood Pressure; Calcium; Disease Models, Animal; Evoked Potentials, Somatosensory; Heart Ra | 1992 |
Further studies of nimodipine in experimental spinal cord injury in the rat.
Topics: Animals; Evoked Potentials; Evoked Potentials, Somatosensory; Male; Nimodipine; Rats; Rats, Inbred S | 1991 |
The effect of nimodipine and dextran on axonal function and blood flow following experimental spinal cord injury.
Topics: Animals; Axons; Blood Volume; Dextrans; Electrophysiology; Hemorrhage; Nimodipine; Rats; Rats, Inbre | 1989 |
Spinal cord injury in rats: inability of nimodipine or anti-neutrophil serum to improve spinal cord blood flow or neurologic status.
Topics: Animals; Immune Sera; Immunization, Passive; Male; Neutrophils; Nimodipine; Rats; Rats, Inbred Strai | 1989 |
Improvement in post-traumatic spinal cord blood flow with a combination of a calcium channel blocker and a vasopressor.
Topics: Animals; Blood Pressure; Drug Therapy, Combination; Epinephrine; Hematocrit; Ischemia; Male; Nimodip | 1989 |
Effect of nimodipine-associated hypotension on recovery from acute spinal cord injury in cats.
Topics: Acute Disease; Animals; Blood Pressure; Cats; Electric Stimulation; Electrocardiography; Evoked Pote | 1988 |
Effect of a calcium channel blocker on posttraumatic spinal cord blood flow.
Topics: Angiotensin II; Animals; Blood Physiological Phenomena; Blood Pressure; Ischemia; Male; Nimodipine; | 1987 |
Failure of nimodipine to reverse acute experimental spinal cord injury.
Topics: Acute Disease; Animals; Calcium Channel Blockers; Cats; Male; Nicotinic Acids; Nimodipine; Spinal Co | 1985 |