nimodipine has been researched along with Hyperventilation in 7 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
Hyperventilation: A pulmonary ventilation rate faster than is metabolically necessary for the exchange of gases. It is the result of an increased frequency of breathing, an increased tidal volume, or a combination of both. It causes an excess intake of oxygen and the blowing off of carbon dioxide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In our miniature swine model simulating operating room brain retraction, we investigated the effects of mannitol plus nimodipine on cerebral blood flow (CBF) and evoked potentials (EP) ipsilateral and contralateral to retraction, in comparison with either agent alone, during both normoventilation and hyperventilation." | 7.68 | Retraction brain ischaemia: mannitol plus nimodipine preserves both cerebral blood flow and evoked potentials during normoventilation and hyperventilation. ( Andrews, RJ; Muto, RP, 1992) |
| "In our miniature swine model simulating operating room brain retraction, we investigated the effects of mannitol plus nimodipine on cerebral blood flow (CBF) and evoked potentials (EP) ipsilateral and contralateral to retraction, in comparison with either agent alone, during both normoventilation and hyperventilation." | 3.68 | Retraction brain ischaemia: mannitol plus nimodipine preserves both cerebral blood flow and evoked potentials during normoventilation and hyperventilation. ( Andrews, RJ; Muto, RP, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Keppel Hesselink, JM | 1 |
| Mathew, RJ | 1 |
| Andrews, RJ | 1 |
| Muto, RP | 1 |
| Gibbs, DM | 1 |
| Kraaier, V | 1 |
| van Huffelen, AC | 1 |
| Wieneke, GH | 1 |
| Hesselink, JM | 1 |
| Young, WL | 1 |
| Chien, S | 1 |
| Messeter, K | 1 |
| Brandt, L | 1 |
| Ljunggren, B | 1 |
| Algotsson, L | 1 |
| Ryding, E | 1 |
1 trial available for nimodipine and Hyperventilation
| Article | Year |
|---|---|
Nimodipine tested in a human model of cerebral ischaemia. Electroencephalographic and transcranial Doppler ultrasound investigations in normal subjects during standardized hyperventilation.
Topics: Adult; Brain; Brain Ischemia; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Double- | 1991 |
6 other studies available for nimodipine and Hyperventilation
| Article | Year |
|---|---|
Hyperventilation-induced cerebral ischemia in panic disorder.
Topics: Blood Flow Velocity; Brain Ischemia; Cerebrovascular Circulation; Humans; Hyperventilation; Male; Ni | 1993 |
Hyperventilation-induced cerebral ischemia in panic disorder.
Topics: Blood Flow Velocity; Brain Ischemia; Carbon Dioxide; Cerebrovascular Circulation; Humans; Hyperventi | 1993 |
Retraction brain ischaemia: mannitol plus nimodipine preserves both cerebral blood flow and evoked potentials during normoventilation and hyperventilation.
Topics: Animals; Blood Pressure; Brain; Carbon Dioxide; Cerebrovascular Circulation; Drug Therapy, Combinati | 1992 |
Hyperventilation-induced cerebral ischemia in panic disorder and effect of nimodipine.
Topics: Adult; Basilar Artery; Blood Flow Velocity; Brain Ischemia; Humans; Hyperventilation; Male; Nimodipi | 1992 |
Effect of nimodipine on cerebral blood flow and metabolism in rats during hyperventilation.
Topics: Animals; Brain; Cerebrovascular Circulation; Glucose; Hyperventilation; Male; Nimodipine; Rats; Rats | 1989 |
Prediction and prevention of delayed ischemic dysfunction in early aneurysm surgery.
Topics: Adult; Brain Ischemia; Cerebrovascular Circulation; Female; Humans; Hyperventilation; Intracranial A | 1987 |