nimodipine has been researched along with Glioma in 9 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this study was to investigate the role of intracellular calcium overload in the in vitro apoptosis of C6 glioma cells mediated by low level ultrasound and hematoporphyrin monomethyl ether (HMME) therapy." | 7.80 | Calcium overload and in vitro apoptosis of the C6 glioma cells mediated by sonodynamic therapy (hematoporphyrin monomethyl ether and ultrasound). ( Che, Z; Hao, D; Liu, Q; Song, Y, 2014) |
| "The effects of nifedipine, niguldipine, nimodipine and nitrendipine on the high K+-induced intracellular Ca2+ ([Ca2+]i) transient in dibutyryl cAMP-differentiated neuroblastoma x glioma hybrid NG 108-15 cells were studied by using the fluorescent Ca2+ indicator fura-2." | 7.69 | Nimodipine and nitrendipine inhibit N-type calcium channels in dibutyryl cAMP-differentiated neuroblastoma x glioma hybrid (NG 108-15) cells. ( Andreas, K; Bräter, M; Li, SN, 1997) |
| "The objective of this study was to investigate the role of intracellular calcium overload in the in vitro apoptosis of C6 glioma cells mediated by low level ultrasound and hematoporphyrin monomethyl ether (HMME) therapy." | 3.80 | Calcium overload and in vitro apoptosis of the C6 glioma cells mediated by sonodynamic therapy (hematoporphyrin monomethyl ether and ultrasound). ( Che, Z; Hao, D; Liu, Q; Song, Y, 2014) |
| "To investigate the possible mechanisms involved in forskolin-induced c-jun mRNA decrease in rat C6 glioma cells, we examined effects of a PKA inhibitor (H-89), a L-type Ca2+ channel blocker (nimodipine), a calmodulin activation inhibitor (calmidazolium chloride) and a Ca2+/calmodulin-dependent protein kinase II inhibitor (KN-62) on forskolin-induced c-jun mRNA down-regulation." | 3.70 | Activation of adenylate cyclase results in down-regulation of c-jun mRNA expression in rat C6 glioma cells. ( Choi, MR; Huh, SO; Kim, YH; Lee, JK; Song, DK; Suh, HW, 1999) |
| "The effects of nifedipine, niguldipine, nimodipine and nitrendipine on the high K+-induced intracellular Ca2+ ([Ca2+]i) transient in dibutyryl cAMP-differentiated neuroblastoma x glioma hybrid NG 108-15 cells were studied by using the fluorescent Ca2+ indicator fura-2." | 3.69 | Nimodipine and nitrendipine inhibit N-type calcium channels in dibutyryl cAMP-differentiated neuroblastoma x glioma hybrid (NG 108-15) cells. ( Andreas, K; Bräter, M; Li, SN, 1997) |
| "The effects of 2 specific calcium channel blockers, verapamil and nimodipine, on the proliferation of human glioma tumour cells were investigated in vitro." | 3.67 | Inhibitory effect of calcium channel blockers on proliferation of human glioma cells in vitro. ( Kunert-Radek, J; Lyson, K; Pawlikowski, M; Radek, A; Stepien, H, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 6 (66.67) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hao, D | 1 |
| Song, Y | 1 |
| Che, Z | 1 |
| Liu, Q | 1 |
| Matsukado, K | 1 |
| Ikezaki, K | 1 |
| Nomura, T | 1 |
| Fukui, M | 1 |
| Li, SN | 1 |
| Bräter, M | 1 |
| Andreas, K | 1 |
| Saqr, HE | 1 |
| Guan, Z | 1 |
| Yates, AJ | 1 |
| Stokes, BT | 1 |
| Lee, JK | 1 |
| Choi, MR | 1 |
| Song, DK | 1 |
| Huh, SO | 1 |
| Kim, YH | 1 |
| Suh, HW | 1 |
| Easter, A | 1 |
| Spruce, AE | 1 |
| Takemura, H | 1 |
| Ohshika, H | 1 |
| Yokosawa, N | 1 |
| Oguma, K | 1 |
| Thastrup, O | 1 |
| Chan, J | 1 |
| Greenberg, DA | 1 |
| Kunert-Radek, J | 1 |
| Stepien, H | 1 |
| Radek, A | 1 |
| Lyson, K | 1 |
| Pawlikowski, M | 1 |
9 other studies available for nimodipine and Glioma
| Article | Year |
|---|---|
Calcium overload and in vitro apoptosis of the C6 glioma cells mediated by sonodynamic therapy (hematoporphyrin monomethyl ether and ultrasound).
Topics: Apoptosis; Calcium; Calcium Channels, L-Type; Cell Line, Tumor; Combined Modality Therapy; Cytochrom | 2014 |
Effect of calcium antagonists on regional cerebral blood flow in transplanted rat brain tumors.
Topics: Analysis of Variance; Animals; Brain; Brain Neoplasms; Calcium Channel Blockers; Cerebrovascular Cir | 1996 |
Nimodipine and nitrendipine inhibit N-type calcium channels in dibutyryl cAMP-differentiated neuroblastoma x glioma hybrid (NG 108-15) cells.
Topics: Animals; Bucladesine; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Differentiation; Dih | 1997 |
Mechanisms through which PDGF alters intracellular calcium levels in U-1242 MG human glioma cells.
Topics: Becaplermin; Brain Neoplasms; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium | 1999 |
Activation of adenylate cyclase results in down-regulation of c-jun mRNA expression in rat C6 glioma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Animals; Calcium Channel Blockers; | 1999 |
Modulation of calcium current by recombinant GABA(B) receptors.
Topics: Animals; Baclofen; Calcium Channel Blockers; Calcium Channels; GABA Agonists; Glioma; Hybrid Cells; | 2000 |
The thapsigargin-sensitive intracellular Ca2+ pool is more important in plasma membrane Ca2+ entry than the IP3-sensitive intracellular Ca2+ pool in neuronal cell lines.
Topics: Animals; Biological Transport; Bradykinin; Calcium; Calcium Channel Blockers; Cell Line; Cell Membra | 1991 |
SK&F 96365, a receptor-mediated calcium entry inhibitor, inhibits calcium responses to endothelin-1 in NG108-15 cells.
Topics: Animals; Calcium; Calcium Channel Blockers; Cell Line; Dose-Response Relationship, Drug; Endothelins | 1991 |
Inhibitory effect of calcium channel blockers on proliferation of human glioma cells in vitro.
Topics: Calcium; Calcium Channel Blockers; Cell Division; Glioma; Humans; Nimodipine; Thymidine; Tumor Cells | 1989 |