Page last updated: 2024-11-01

nimodipine and Facial Palsy

nimodipine has been researched along with Facial Palsy in 6 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Research Excerpts

ExcerptRelevanceReference
"The delayed onset of a facial paresis following termination of vasoactive treatment points to a disturbed microcirculation of the nerve as the main pathophysiological feature."1.32Delayed facial nerve paresis following acoustic neuroma resection and postoperative vasoactive treatment. ( Fahlbusch, R; Romstöck, J; Scheller, C; Strauss, C, 2004)
"Nimodipine, which acts as an antagonist to L-type voltage-gated calcium channels, has been shown to be neuroprotective in various lesion models of the central and peripheral nervous systems."1.30Nimodipine-induced improved survival rate of facial motor neurons following intracranial transection of the facial nerve in the adult rat. ( Aldskogius, H; Mattsson, P; Svensson, M, 1999)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Tian, W1
Meng, X1
Zou, J1
Colbert, S1
Coombes, D1
Godden, D1
Cascarini, L1
Kerawala, C1
Brennan, PA1
Youssef, AS1
Downes, AE1
Scheller, K1
Scheller, C2
Strauss, C1
Fahlbusch, R1
Romstöck, J1
Mattsson, P1
Aldskogius, H1
Svensson, M1

Reviews

1 review available for nimodipine and Facial Palsy

ArticleYear
Intraoperative neurophysiological monitoring in vestibular schwannoma surgery: advances and clinical implications.
    Neurosurgical focus, 2009, Volume: 27, Issue:4

    Topics: Action Potentials; Cochlear Nerve; Electromyography; Evoked Potentials, Auditory, Brain Stem; Facial

2009

Other Studies

5 other studies available for nimodipine and Facial Palsy

ArticleYear
Delayed Facial Palsy after Microvascular Decompression for Trigeminal Neuralgia.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2020, Volume: 30, Issue:3

    Topics: Acyclovir; Aged; Drug Therapy, Combination; Facial Paralysis; Humans; Male; Methylprednisolone; Micr

2020
How do I manage an acute injury to the facial nerve?
    The British journal of oral & maxillofacial surgery, 2014, Volume: 52, Issue:1

    Topics: Anastomosis, Surgical; Calcium Channel Blockers; Cranial Nerves; Facial Nerve Injuries; Facial Paral

2014
Nimodipine promotes regeneration of peripheral facial nerve function after traumatic injury following maxillofacial surgery: an off label pilot-study.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2012, Volume: 40, Issue:5

    Topics: Adolescent; Adult; Aged; Facial Bones; Facial Nerve; Facial Nerve Injuries; Facial Paralysis; Female

2012
Delayed facial nerve paresis following acoustic neuroma resection and postoperative vasoactive treatment.
    Zentralblatt fur Neurochirurgie, 2004, Volume: 65, Issue:3

    Topics: Adult; Electric Stimulation; Electromyography; Facial Nerve Diseases; Facial Paralysis; Female; Huma

2004
Nimodipine-induced improved survival rate of facial motor neurons following intracranial transection of the facial nerve in the adult rat.
    Journal of neurosurgery, 1999, Volume: 90, Issue:4

    Topics: Administration, Oral; Animals; Astrocytes; Brain Stem; Calcium Channel Blockers; Cell Count; Cell Su

1999