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nimodipine and Epilepsy, Absence

nimodipine has been researched along with Epilepsy, Absence in 3 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Epilepsy, Absence: A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)

Research Excerpts

ExcerptRelevanceReference
"ethosuximide, an increase after i."1.31Opposite effects of T- and L-type Ca(2+) channels blockers in generalized absence epilepsy. ( Elants, C; Scheenen, W; van Luijtelaar, G; Wiaderna, D, 2000)
"Although calcium antagonists possess antiepileptic properties in various models of epilepsy, their role after chronic administration and in models for generalized absence epilepsy has not been studied."1.29The effects of chronic treatment with a calcium channel antagonist on two types of generalized epilepsies in rats. ( Ates, N; van der Staay, FJ; van Luijtelaar, EL, 1994)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van Luijtelaar, EL2
Ates, N2
Coenen, AM1
van der Staay, FJ1
van Luijtelaar, G1
Wiaderna, D1
Elants, C1
Scheenen, W1

Other Studies

3 other studies available for nimodipine and Epilepsy, Absence

ArticleYear
Role of L-type calcium channel modulation in nonconvulsive epilepsy in rats.
    Epilepsia, 1995, Volume: 36, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
The effects of chronic treatment with a calcium channel antagonist on two types of generalized epilepsies in rats.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 48, Issue:3

    Topics: Animals; Calcium Channel Blockers; Diet; Electroencephalography; Epilepsy, Absence; Epilepsy, Genera

1994
Opposite effects of T- and L-type Ca(2+) channels blockers in generalized absence epilepsy.
    European journal of pharmacology, 2000, Oct-20, Volume: 406, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2000