nimodipine has been researched along with Edema-Proteinuria-Hypertension Gestosis in 8 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the effects of nimodipine on retinal blood flow in patients with pregnancy induced hypertension (PIH)." | 9.08 | [The effect of nimodipine on retinal blood flow in pregnancy induced hypertension]. ( Li, M; Qiu, X; Yang, M, 1998) |
| "Patients with severe preeclampsia were randomly selected to receive magnesium sulfate (6 g bolus and 2 g/hr intravenous infusion) or nimodipine (60 mg taken orally every 4 hours)." | 6.69 | Change in estimated cerebral perfusion pressure after treatment with nimodipine or magnesium sulfate in patients with preeclampsia. ( Belfort, MA; Grunewald, C; Herd, JA; Nisell, H; Saade, GR; Varner, MA; Yared, M, 1999) |
| "To assess the effects of nimodipine on retinal blood flow in patients with pregnancy induced hypertension (PIH)." | 5.08 | [The effect of nimodipine on retinal blood flow in pregnancy induced hypertension]. ( Li, M; Qiu, X; Yang, M, 1998) |
| "Patients with severe preeclampsia were randomly selected to receive magnesium sulfate (6 g bolus and 2 g/hr intravenous infusion) or nimodipine (60 mg taken orally every 4 hours)." | 2.69 | Change in estimated cerebral perfusion pressure after treatment with nimodipine or magnesium sulfate in patients with preeclampsia. ( Belfort, MA; Grunewald, C; Herd, JA; Nisell, H; Saade, GR; Varner, MA; Yared, M, 1999) |
| "Medical treatment of severe hypertension in pregnancy is required." | 2.41 | Management and monitoring of severe preeclampsia. ( Bolte, AC; Dekker, GA; van Geijn, HP, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (62.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fogleman, CD | 1 |
| Hollenberg, NK | 1 |
| Serra-Serra, V | 1 |
| Redman, CW | 1 |
| Belfort, MA | 2 |
| Saade, GR | 2 |
| Moise, KJ | 1 |
| Cruz, A | 1 |
| Adam, K | 1 |
| Kramer, W | 1 |
| Kirshon, B | 1 |
| Kaya, T | 1 |
| Cetin, A | 1 |
| Cetin, M | 1 |
| Sarioglu, Y | 1 |
| Yared, M | 1 |
| Grunewald, C | 1 |
| Herd, JA | 1 |
| Varner, MA | 1 |
| Nisell, H | 1 |
| Li, M | 1 |
| Yang, M | 1 |
| Qiu, X | 1 |
| Bolte, AC | 1 |
| van Geijn, HP | 1 |
| Dekker, GA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Labetalol Versus MgSO4 for the Prevention of Eclampsia Trial (LAMPET)[NCT00293735] | Phase 2/Phase 3 | 0 participants (Actual) | Interventional | 2015-06-30 | Withdrawn (stopped due to Lack of funding) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nimodipine and Edema-Proteinuria-Hypertension Gestosis
| Article | Year |
|---|---|
Management and monitoring of severe preeclampsia.
Topics: Adrenal Cortex Hormones; Antihypertensive Agents; Blood Pressure Determination; Female; Fetal Diseas | 2001 |
4 trials available for nimodipine and Edema-Proteinuria-Hypertension Gestosis
| Article | Year |
|---|---|
A comparison of magnesium sulfate and nimodipine for the prevention of eclampsia.
Topics: Calcium Channel Blockers; Eclampsia; Female; Humans; Magnesium Sulfate; Nimodipine; Pre-Eclampsia; P | 2003 |
Nimodipine in the management of preeclampsia: maternal and fetal effects.
Topics: Adult; Female; Fetus; Heart Rate, Fetal; Hemodynamics; Humans; Nimodipine; Pre-Eclampsia; Pregnancy | 1994 |
Change in estimated cerebral perfusion pressure after treatment with nimodipine or magnesium sulfate in patients with preeclampsia.
Topics: Adult; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Cerebral Arteries; Female; Hum | 1999 |
[The effect of nimodipine on retinal blood flow in pregnancy induced hypertension].
Topics: Adult; Blood Flow Velocity; Female; Humans; Nimodipine; Pre-Eclampsia; Pregnancy; Retinal Artery; Va | 1998 |
3 other studies available for nimodipine and Edema-Proteinuria-Hypertension Gestosis
| Article | Year |
|---|---|
Magnesium sulfate and other anticonvulsants for women with preeclampsia.
Topics: Anticonvulsants; Clinical Trials as Topic; Evidence-Based Medicine; Female; Humans; Magnesium Sulfat | 2011 |
Cerebral hemodynamics in relation to antihypertensive medication.
Topics: Cerebrovascular Circulation; Female; Hemodynamics; Humans; Nimodipine; Pre-Eclampsia; Pregnancy; Ult | 1995 |
Effect of endothelin-1 on spontaneous contractions and effects of nimodipine and isradipine on endothelin-1-induced contractions in myometrial strips isolated from normal pregnant and preeclamptic women.
Topics: Calcium Channel Blockers; Dose-Response Relationship, Drug; Endothelin-1; Female; Humans; In Vitro T | 1998 |