nimodipine has been researched along with Dementia Multi-Infarct in 5 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vascular dementia is second most common cause of dementia." | 2.43 | [Pharmacological treatment of vascular cognitive impairment]. ( Bidzan, L, 2006) |
| "Nimodipine is a calcium antagonist which improves learning and memory in brain-lesioned or aged animals (LeVere & Sandin, 1989; Schuurman & Traber, 1989)." | 2.38 | Global rating, symptoms, behavior, and cognitive performance as indicators of efficacy in clinical studies with nimodipine in elderly patients with cognitive impairment syndromes. ( Bergener, M; Schmage, N, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bidzan, L | 1 |
| Fischhof, PK | 1 |
| Pantoni, L | 1 |
| Bianchi, C | 1 |
| Beneke, M | 1 |
| Inzitari, D | 1 |
| Wallin, A | 1 |
| Erkinjuntti, T | 1 |
| Pellicanò, S | 1 |
| Costa, A | 1 |
| Terra, L | 1 |
| Schmage, N | 1 |
| Bergener, M | 1 |
2 reviews available for nimodipine and Dementia Multi-Infarct
| Article | Year |
|---|---|
[Pharmacological treatment of vascular cognitive impairment].
Topics: Animals; Cerebrovascular Disorders; Cognition Disorders; Dementia, Multi-Infarct; Dementia, Vascular | 2006 |
Global rating, symptoms, behavior, and cognitive performance as indicators of efficacy in clinical studies with nimodipine in elderly patients with cognitive impairment syndromes.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Attention; Dementia, Multi-Infarct; Humans; Mental Recal | 1992 |
2 trials available for nimodipine and Dementia Multi-Infarct
| Article | Year |
|---|---|
Divergent neuroprotective effects of nimodipine in PDD and MID provide indirect evidence of disturbances in Ca2+ homeostasis in dementia.
Topics: Aged; Aged, 80 and over; Aging; Calcium; Cognition; Dementia; Dementia, Multi-Infarct; Double-Blind | 1993 |
The Scandinavian Multi-Infarct Dementia Trial: a double-blind, placebo-controlled trial on nimodipine in multi-infarct dementia.
Topics: Aged; Aged, 80 and over; Calcium Channel Blockers; Cognition; Dementia, Multi-Infarct; Denmark; Doub | 2000 |
1 other study available for nimodipine and Dementia Multi-Infarct
| Article | Year |
|---|---|
[Two case reports of cerebral autosomal dominant arteriophaty with subcortical infarctions and leukoencephalopathy (CADASIL)].
Topics: Adult; Alprazolam; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dementia, Multi-Infarct; Drug T | 2001 |