Page last updated: 2024-11-01

nimodipine and Deficiency, Folic Acid

nimodipine has been researched along with Deficiency, Folic Acid in 1 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Research Excerpts

ExcerptRelevanceReference
"Treatment with nimodipine [an L voltage-sensitive calcium channel (LVSCC) antagonist], MK-801 (an NMDA channel antagonist) and thapsigarin (an inhibitor of efflux of calcium from internal stores) indicated that folate deprivation initially induced calcium influx via the LVSCC, with subsequent additional calcium derived from NMDA channels and internal stores."1.32Folate deficiency and homocysteine induce toxicity in cultured dorsal root ganglion neurons via cytosolic calcium accumulation. ( Dhivant, S; Mitton, K; Ortiz, DO; Rogers, E; Shea, TB; Tjiattas, L, 2004)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tjiattas, L1
Ortiz, DO1
Dhivant, S1
Mitton, K1
Rogers, E1
Shea, TB1

Other Studies

1 other study available for nimodipine and Deficiency, Folic Acid

ArticleYear
Folate deficiency and homocysteine induce toxicity in cultured dorsal root ganglion neurons via cytosolic calcium accumulation.
    Aging cell, 2004, Volume: 3, Issue:2

    Topics: Adenine; Aniline Compounds; Animals; Calcium; Cells, Cultured; Chick Embryo; Cytosol; Dizocilpine Ma

2004