nimodipine has been researched along with Craniocerebral Trauma in 18 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
Craniocerebral Trauma: Traumatic injuries involving the cranium and intracranial structures (i.e., BRAIN; CRANIAL NERVES; MENINGES; and other structures). Injuries may be classified by whether or not the skull is penetrated (i.e., penetrating vs. nonpenetrating) or whether there is an associated hemorrhage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A short overview on trials in subarachnoid hemorrhage, head injury, ischemic stroke and cerebral resuscitation is given in this paper." | 6.39 | Clinical experiences with nimodipine in cerebral ischemia. ( Fritze, J; Kakarieka, A; Schakel, EH, 1994) |
| "Eighty patients with severe head injuries were randomly divided into two groups: one group received conventional therapy, including craniotomy, hemostasis, dehydration, anti-infection and corticosteroid administration and the other group received nimodipine on the basis of conventional therapy lasting till 30 d after injuries." | 2.70 | Effects of nimodipine on the cerebrovascular hemodynamics in patients with severe head injuries. ( Ke, YQ; Wang, QH; Wang, XY; Xu, RX; Yang, ZL; Zhou, XE, 2002) |
| "A short overview on trials in subarachnoid hemorrhage, head injury, ischemic stroke and cerebral resuscitation is given in this paper." | 2.39 | Clinical experiences with nimodipine in cerebral ischemia. ( Fritze, J; Kakarieka, A; Schakel, EH, 1994) |
| "Severe head trauma may increase oxidative stress." | 1.38 | Nimodipine can diminish oxidative stress in patients with severe head trauma. ( Aslan, A; Buyukokuroglu, M; Cemek, M; Eser, O; Goksel, HM; Gurelik, M, 2012) |
| "Nimodipine was administered into the peripheral vein to prevent secondary neuronal damages in patients." | 1.35 | Nimodipine can improve cerebral metabolism and outcome in patients with severe head trauma. ( Aslan, A; Buyukokuroglu, ME; Cemek, M; Goksel, HM; Gurelik, M, 2009) |
| "Group 3 (n = 10) received head trauma and intravenous (IV) 2 microgr/kg nimodipine." | 1.31 | Effects of nimodipine and magnesium sulfate on endogenous antioxidant levels in brain tissue after experimental head trauma. ( Ak, A; Duman, A; Oğun, CO; Ustün, ME; Vatansev, H, 2001) |
| "Group 2 (n=10) received head trauma without treatment and in group 3 (n=10) nimodipine was administered for 30 minutes intravenously (2 microg/kg/min) immediately after head trauma." | 1.31 | Effects of nimodipine on tissue lactate and malondialdehyde levels in experimental head trauma. ( Ak, A; Bor, MA; Duman, A; Oğün, CO; Ustün, ME, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (38.89) | 18.2507 |
| 2000's | 9 (50.00) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Kamasak, K | 1 |
| Basarslan, K | 1 |
| Dagli, AT | 1 |
| Ogden, M | 1 |
| Alabalik, U | 1 |
| Ekinci, A | 1 |
| Ceviz, A | 1 |
| Aslan, A | 2 |
| Gurelik, M | 2 |
| Cemek, M | 2 |
| Goksel, HM | 2 |
| Buyukokuroglu, ME | 1 |
| Duman, A | 3 |
| Duman, I | 1 |
| Ogun, CO | 3 |
| Buyukokuroglu, M | 1 |
| Eser, O | 1 |
| Zhou, XE | 1 |
| Wang, XY | 1 |
| Xu, RX | 1 |
| Wang, QH | 1 |
| Ke, YQ | 1 |
| Yang, ZL | 1 |
| Pillai, SV | 1 |
| Kolluri, VR | 1 |
| Mohanty, A | 1 |
| Chandramouli, BA | 1 |
| Kumar, S | 1 |
| Nandigam, K | 1 |
| Kakarieka, A | 2 |
| Schakel, EH | 1 |
| Fritze, J | 1 |
| Piek, J | 1 |
| Cunitz, G | 1 |
| Patel, HC | 1 |
| Hutchinson, PJ | 1 |
| Pickard, JD | 1 |
| Ustün, ME | 2 |
| Vatansev, H | 1 |
| Ak, A | 2 |
| Bor, MA | 1 |
| Shen, G | 1 |
| Zhou, Y | 1 |
| Xu, M | 1 |
| Liu, B | 1 |
| Xu, Y | 1 |
| Teasdale, G | 1 |
| Bailey, I | 1 |
| Bell, A | 1 |
| Gray, J | 1 |
| Gullan, R | 1 |
| Heiskanan, U | 1 |
| Marks, PV | 1 |
| Marsh, H | 1 |
| Mendelow, AD | 1 |
| Murray, G | 1 |
| Kostron, H | 1 |
| Grunert, V | 1 |
3 reviews available for nimodipine and Craniocerebral Trauma
| Article | Year |
|---|---|
Clinical experiences with nimodipine in cerebral ischemia.
Topics: Brain Ischemia; Cerebrovascular Disorders; Clinical Trials as Topic; Craniocerebral Trauma; Humans; | 1994 |
Review on traumatic subarachnoid hemorrhage.
Topics: Calcium Channel Blockers; Craniocerebral Trauma; Humans; Nimodipine; Subarachnoid Hemorrhage; Wounds | 1997 |
Traumatic subarachnoid haemorrhage.
Topics: Calcium Channel Blockers; Craniocerebral Trauma; Humans; Ischemic Attack, Transient; Nimodipine; Ris | 1999 |
3 trials available for nimodipine and Craniocerebral Trauma
| Article | Year |
|---|---|
Effects of nimodipine on the cerebrovascular hemodynamics in patients with severe head injuries.
Topics: Adolescent; Adult; Calcium Channel Blockers; Cerebrovascular Circulation; Craniocerebral Trauma; Fem | 2002 |
Evaluation of nimodipine in the treatment of severe diffuse head injury: a double-blind placebo-controlled trial.
Topics: Adolescent; Adult; Calcium Channel Blockers; Craniocerebral Trauma; Double-Blind Method; Female; Hum | 2003 |
The effect of nimodipine on outcome after head injury: a prospective randomised control trial. The British/Finnish Co-operative Head Injury Trial Group.
Topics: Craniocerebral Trauma; Humans; Nimodipine; Prognosis; Prospective Studies | 1990 |
12 other studies available for nimodipine and Craniocerebral Trauma
| Article | Year |
|---|---|
Effects of Nimodipine and Nigella sativa on Oxidative Stress and Apoptosis in Serum and Brain Tissue of Rats with Experimental Head Trauma.
Topics: Animals; Antioxidants; Apoptosis; Brain Injuries, Traumatic; Craniocerebral Trauma; Male; Nigella sa | 2021 |
Nimodipine can improve cerebral metabolism and outcome in patients with severe head trauma.
Topics: Adult; Brain; Calcium; Calcium Channel Blockers; Craniocerebral Trauma; Female; Humans; Male; Middle | 2009 |
Is nimodipine really effective in head trauma?
Topics: Calcium Channel Blockers; Craniocerebral Trauma; Humans; Nimodipine | 2009 |
Nimodipine can diminish oxidative stress in patients with severe head trauma.
Topics: Adolescent; Adult; Antioxidants; Ascorbic Acid; beta Carotene; Calcium Channel Blockers; Child; Cran | 2012 |
Nimodipine in severe head injury.
Topics: Calcium Channel Blockers; Craniocerebral Trauma; Humans; Nimodipine; Randomized Controlled Trials as | 2004 |
Role of nimodipine in severe diffuse head injury.
Topics: Calcium Channel Blockers; Craniocerebral Trauma; Humans; Nimodipine; Randomized Controlled Trials as | 2004 |
Traumatic subarachnoid hemorrhage.
Topics: Craniocerebral Trauma; Humans; Nimodipine; Subarachnoid Hemorrhage; Treatment Outcome | 1997 |
Early management of head injury.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiaz | 1997 |
Effects of nimodipine and magnesium sulfate on endogenous antioxidant levels in brain tissue after experimental head trauma.
Topics: Analysis of Variance; Animals; Antioxidants; Blood Pressure; Brain; Brain Injuries; Carbon Dioxide; | 2001 |
Effects of nimodipine on tissue lactate and malondialdehyde levels in experimental head trauma.
Topics: Animals; Calcium Channel Blockers; Craniocerebral Trauma; Female; Lactic Acid; Male; Malondialdehyde | 2001 |
Effects of nimodipine on changes of endothelin after head injury in rabbits.
Topics: Animals; Brain; Brain Injuries; Calcium Channel Blockers; Craniocerebral Trauma; Endothelins; Nimodi | 2001 |
Calcium entry blocker effects on ischemic brain damage after severe head injury.
Topics: Brain Edema; Craniocerebral Trauma; Drug Evaluation; Humans; Intracranial Pressure; Nimodipine; Pilo | 1990 |