nimodipine has been researched along with Craniocerebral Injuries in 18 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A short overview on trials in subarachnoid hemorrhage, head injury, ischemic stroke and cerebral resuscitation is given in this paper." | 6.39 | Clinical experiences with nimodipine in cerebral ischemia. ( Fritze, J; Kakarieka, A; Schakel, EH, 1994) |
| "Eighty patients with severe head injuries were randomly divided into two groups: one group received conventional therapy, including craniotomy, hemostasis, dehydration, anti-infection and corticosteroid administration and the other group received nimodipine on the basis of conventional therapy lasting till 30 d after injuries." | 2.70 | Effects of nimodipine on the cerebrovascular hemodynamics in patients with severe head injuries. ( Ke, YQ; Wang, QH; Wang, XY; Xu, RX; Yang, ZL; Zhou, XE, 2002) |
| "A short overview on trials in subarachnoid hemorrhage, head injury, ischemic stroke and cerebral resuscitation is given in this paper." | 2.39 | Clinical experiences with nimodipine in cerebral ischemia. ( Fritze, J; Kakarieka, A; Schakel, EH, 1994) |
| "Severe head trauma may increase oxidative stress." | 1.38 | Nimodipine can diminish oxidative stress in patients with severe head trauma. ( Aslan, A; Buyukokuroglu, M; Cemek, M; Eser, O; Goksel, HM; Gurelik, M, 2012) |
| "Nimodipine was administered into the peripheral vein to prevent secondary neuronal damages in patients." | 1.35 | Nimodipine can improve cerebral metabolism and outcome in patients with severe head trauma. ( Aslan, A; Buyukokuroglu, ME; Cemek, M; Goksel, HM; Gurelik, M, 2009) |
| "Group 3 (n = 10) received head trauma and intravenous (IV) 2 microgr/kg nimodipine." | 1.31 | Effects of nimodipine and magnesium sulfate on endogenous antioxidant levels in brain tissue after experimental head trauma. ( Ak, A; Duman, A; Oğun, CO; Ustün, ME; Vatansev, H, 2001) |
| "Group 2 (n=10) received head trauma without treatment and in group 3 (n=10) nimodipine was administered for 30 minutes intravenously (2 microg/kg/min) immediately after head trauma." | 1.31 | Effects of nimodipine on tissue lactate and malondialdehyde levels in experimental head trauma. ( Ak, A; Bor, MA; Duman, A; Oğün, CO; Ustün, ME, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (38.89) | 18.2507 |
| 2000's | 9 (50.00) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Kamasak, K | 1 |
| Basarslan, K | 1 |
| Dagli, AT | 1 |
| Ogden, M | 1 |
| Alabalik, U | 1 |
| Ekinci, A | 1 |
| Ceviz, A | 1 |
| Aslan, A | 2 |
| Gurelik, M | 2 |
| Cemek, M | 2 |
| Goksel, HM | 2 |
| Buyukokuroglu, ME | 1 |
| Duman, A | 3 |
| Duman, I | 1 |
| Ogun, CO | 3 |
| Buyukokuroglu, M | 1 |
| Eser, O | 1 |
| Zhou, XE | 1 |
| Wang, XY | 1 |
| Xu, RX | 1 |
| Wang, QH | 1 |
| Ke, YQ | 1 |
| Yang, ZL | 1 |
| Pillai, SV | 1 |
| Kolluri, VR | 1 |
| Mohanty, A | 1 |
| Chandramouli, BA | 1 |
| Kumar, S | 1 |
| Nandigam, K | 1 |
| Kakarieka, A | 2 |
| Schakel, EH | 1 |
| Fritze, J | 1 |
| Piek, J | 1 |
| Cunitz, G | 1 |
| Patel, HC | 1 |
| Hutchinson, PJ | 1 |
| Pickard, JD | 1 |
| Ustün, ME | 2 |
| Vatansev, H | 1 |
| Ak, A | 2 |
| Bor, MA | 1 |
| Shen, G | 1 |
| Zhou, Y | 1 |
| Xu, M | 1 |
| Liu, B | 1 |
| Xu, Y | 1 |
| Teasdale, G | 1 |
| Bailey, I | 1 |
| Bell, A | 1 |
| Gray, J | 1 |
| Gullan, R | 1 |
| Heiskanan, U | 1 |
| Marks, PV | 1 |
| Marsh, H | 1 |
| Mendelow, AD | 1 |
| Murray, G | 1 |
| Kostron, H | 1 |
| Grunert, V | 1 |
3 reviews available for nimodipine and Craniocerebral Injuries
| Article | Year |
|---|---|
Clinical experiences with nimodipine in cerebral ischemia.
Topics: Brain Ischemia; Cerebrovascular Disorders; Clinical Trials as Topic; Craniocerebral Trauma; Humans; | 1994 |
Review on traumatic subarachnoid hemorrhage.
Topics: Calcium Channel Blockers; Craniocerebral Trauma; Humans; Nimodipine; Subarachnoid Hemorrhage; Wounds | 1997 |
Traumatic subarachnoid haemorrhage.
Topics: Calcium Channel Blockers; Craniocerebral Trauma; Humans; Ischemic Attack, Transient; Nimodipine; Ris | 1999 |
3 trials available for nimodipine and Craniocerebral Injuries
| Article | Year |
|---|---|
Effects of nimodipine on the cerebrovascular hemodynamics in patients with severe head injuries.
Topics: Adolescent; Adult; Calcium Channel Blockers; Cerebrovascular Circulation; Craniocerebral Trauma; Fem | 2002 |
Evaluation of nimodipine in the treatment of severe diffuse head injury: a double-blind placebo-controlled trial.
Topics: Adolescent; Adult; Calcium Channel Blockers; Craniocerebral Trauma; Double-Blind Method; Female; Hum | 2003 |
The effect of nimodipine on outcome after head injury: a prospective randomised control trial. The British/Finnish Co-operative Head Injury Trial Group.
Topics: Craniocerebral Trauma; Humans; Nimodipine; Prognosis; Prospective Studies | 1990 |
12 other studies available for nimodipine and Craniocerebral Injuries
| Article | Year |
|---|---|
Effects of Nimodipine and Nigella sativa on Oxidative Stress and Apoptosis in Serum and Brain Tissue of Rats with Experimental Head Trauma.
Topics: Animals; Antioxidants; Apoptosis; Brain Injuries, Traumatic; Craniocerebral Trauma; Male; Nigella sa | 2021 |
Nimodipine can improve cerebral metabolism and outcome in patients with severe head trauma.
Topics: Adult; Brain; Calcium; Calcium Channel Blockers; Craniocerebral Trauma; Female; Humans; Male; Middle | 2009 |
Is nimodipine really effective in head trauma?
Topics: Calcium Channel Blockers; Craniocerebral Trauma; Humans; Nimodipine | 2009 |
Nimodipine can diminish oxidative stress in patients with severe head trauma.
Topics: Adolescent; Adult; Antioxidants; Ascorbic Acid; beta Carotene; Calcium Channel Blockers; Child; Cran | 2012 |
Nimodipine in severe head injury.
Topics: Calcium Channel Blockers; Craniocerebral Trauma; Humans; Nimodipine; Randomized Controlled Trials as | 2004 |
Role of nimodipine in severe diffuse head injury.
Topics: Calcium Channel Blockers; Craniocerebral Trauma; Humans; Nimodipine; Randomized Controlled Trials as | 2004 |
Traumatic subarachnoid hemorrhage.
Topics: Craniocerebral Trauma; Humans; Nimodipine; Subarachnoid Hemorrhage; Treatment Outcome | 1997 |
Early management of head injury.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiaz | 1997 |
Effects of nimodipine and magnesium sulfate on endogenous antioxidant levels in brain tissue after experimental head trauma.
Topics: Analysis of Variance; Animals; Antioxidants; Blood Pressure; Brain; Brain Injuries; Carbon Dioxide; | 2001 |
Effects of nimodipine on tissue lactate and malondialdehyde levels in experimental head trauma.
Topics: Animals; Calcium Channel Blockers; Craniocerebral Trauma; Female; Lactic Acid; Male; Malondialdehyde | 2001 |
Effects of nimodipine on changes of endothelin after head injury in rabbits.
Topics: Animals; Brain; Brain Injuries; Calcium Channel Blockers; Craniocerebral Trauma; Endothelins; Nimodi | 2001 |
Calcium entry blocker effects on ischemic brain damage after severe head injury.
Topics: Brain Edema; Craniocerebral Trauma; Drug Evaluation; Humans; Intracranial Pressure; Nimodipine; Pilo | 1990 |