Page last updated: 2024-11-01

nimodipine and Coronary Disease

nimodipine has been researched along with Coronary Disease in 4 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
" An increasing dosage of nimodipine is accompanied by increasing cardiovascular effects."2.66[Hemodynamic effects in high-dose infusion of nimodipine, a new calcium antagonist]. ( Boldt, J; Hempelmann, G; Kling, D; Moosdorf, R; Ratthey, K; von Bormann, B, 1986)
"03 mg/kg bwxh nimodipine, a dosage being used in neurosurgery, can be classified as safe."2.66[Hemodynamic changes in infusion with nimodipine]. ( Boldt, J; Görlach, G; Hempelmann, G; Kling, D; von Bormann, B, 1985)
"Brain damage after resuscitation from cardiac arrest is believed to be related to calcium influx in ischaemic neurons and to postischaemic calcium-dependent vasospasm."1.28Nimodipine has no beneficial effect on neurological outcome in a cardiopulmonary arrest model in the rat. ( Bogaert, MG; Buylaert, WA; Calle, PA; De Ridder, L, 1990)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Roine, RO1
Calle, PA1
Bogaert, MG1
De Ridder, L1
Buylaert, WA1
Boldt, J2
von Bormann, B2
Kling, D2
Ratthey, K1
Moosdorf, R1
Hempelmann, G2
Görlach, G1

Trials

2 trials available for nimodipine and Coronary Disease

ArticleYear
[Hemodynamic effects in high-dose infusion of nimodipine, a new calcium antagonist].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1986, Volume: 21, Issue:5

    Topics: Coronary Artery Bypass; Coronary Disease; Dose-Response Relationship, Drug; Hemodynamics; Humans; Hy

1986
[Hemodynamic changes in infusion with nimodipine].
    Der Anaesthesist, 1985, Volume: 34, Issue:5

    Topics: Anesthesia, General; Calcium Channel Blockers; Coronary Artery Bypass; Coronary Disease; Dose-Respon

1985

Other Studies

2 other studies available for nimodipine and Coronary Disease

ArticleYear
Nimodipine in patients with heart disease.
    Circulation, 1996, Apr-01, Volume: 93, Issue:7

    Topics: Antihypertensive Agents; Calcium Channel Blockers; Cerebrovascular Disorders; Clinical Trials as Top

1996
Nimodipine has no beneficial effect on neurological outcome in a cardiopulmonary arrest model in the rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 341, Issue:6

    Topics: Animals; Blood Pressure; Cell Survival; Coronary Disease; Disease Models, Animal; Electrocardiograph

1990