nimodipine has been researched along with Complication, Postoperative in 64 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the cost-effectiveness ratio of nimodipine administration after aneurysmal subarachnoid hemorrhage (SAH) and surgery." | 9.09 | Cost-effectiveness analysis of nimodipine treatment after aneurysmal subarachnoid hemorrhage and surgery. ( Karinen, P; Koivukangas, J; Koivukangas, P; Ohinmaa, A; Ohman, J, 1999) |
| "We enrolled 75 consecutive patients admitted with subarachnoid hemorrhages in a randomized, double-blind, placebo-controlled trial to determine the effect of early intervention with nimodipine on outcome and cerebral blood flow." | 9.06 | Controlled study of nimodipine in aneurysm patients treated early after subarachnoid hemorrhage. ( Dorrance, D; Lowe, D; Mee, E; Neil-Dwyer, G, 1988) |
| "Experimental and clinical studies have been performed to investigate the validity of a pharmacological approach to prevent delayed ischemic neurologic deficit from vasospasm after subarachnoid hemorrhage: the calcium channel blocker nimodipine was administered intravenously and perivascularly." | 9.05 | Preventive nimodipine and acute aneurysm surgery. Heading for the control of complications after aneurysmal subarachnoid hemorrhage. ( Auer, LM, 1985) |
| "Fifty-three percent of patients developed new cerebral infarction after intraarterial nimodipine and additional PTA in selected cases." | 7.91 | Complication rate of intraarterial treatment of severe cerebral vasospasm after subarachnoid hemorrhage with nimodipine and percutaneous transluminal balloon angioplasty: Worth the risk? ( Adami, D; Berkefeld, J; Konczalla, J; Pfeilschifter, W; Platz, J; Wagner, M; Weidauer, S, 2019) |
| "The efficacy and tolerability of the dihydropyridine calcium antagonist nimodipine (BAY e 9736) in the prophylaxis of ischemic neurological deficits after subarachnoid hemorrhage were investigated in 171 patients in an open, prospective, multicenter study." | 7.67 | Clinical experience with nimodipine in the prophylaxis of neurological deficits after subarachnoid hemorrhage. ( Adelt, D; Ammerer, HP; Baumann, H; Böker, DK; Grotenhuis, JA; Istaitih, AR; Jaksche, H; Karnick, R; Kazner, E; Sprung, C, 1985) |
| "Intravenous Nimodipine was administered to 109 patients (65 female and 44 male) with either pre- or post-operative progressive neurological deterioration from cerebral vasospasm following subarachnoid hemorrhage from a ruptured aneurysm." | 7.67 | Nimodipine treatment of ischemic neurological deficits due to cerebral vasospasm after subarachnoid hemorrhage. Clinical results of a multicenter study. ( Auer, LM; Böker, DK; Gaab, M; Jaksche, H; Koos, WT; Kostron, H; Meinig, G; Muizelaar, JP; Perneczky, A; van der Werf, AJ, 1985) |
| "Nimodipine is a clinical commonly used calcium antagonistscan lowering the apoptosis rate of hippocampal neuron to reduce the incidence of postoperative cognitive dysfunction (POCD)." | 6.84 | Effects of nimodipine on postoperative delirium in elderly under general anesthesia: A prospective, randomized, controlled clinical trial. ( Guo, YY; Huo, SP; Li, YN; Wang, L; Wang, QJ; Yin, CP; Zhang, Q, 2017) |
| "To assess the cost-effectiveness ratio of nimodipine administration after aneurysmal subarachnoid hemorrhage (SAH) and surgery." | 5.09 | Cost-effectiveness analysis of nimodipine treatment after aneurysmal subarachnoid hemorrhage and surgery. ( Karinen, P; Koivukangas, J; Koivukangas, P; Ohinmaa, A; Ohman, J, 1999) |
| "We enrolled 75 consecutive patients admitted with subarachnoid hemorrhages in a randomized, double-blind, placebo-controlled trial to determine the effect of early intervention with nimodipine on outcome and cerebral blood flow." | 5.06 | Controlled study of nimodipine in aneurysm patients treated early after subarachnoid hemorrhage. ( Dorrance, D; Lowe, D; Mee, E; Neil-Dwyer, G, 1988) |
| "Experimental and clinical studies have been performed to investigate the validity of a pharmacological approach to prevent delayed ischemic neurologic deficit from vasospasm after subarachnoid hemorrhage: the calcium channel blocker nimodipine was administered intravenously and perivascularly." | 5.05 | Preventive nimodipine and acute aneurysm surgery. Heading for the control of complications after aneurysmal subarachnoid hemorrhage. ( Auer, LM, 1985) |
| "Fifty-three percent of patients developed new cerebral infarction after intraarterial nimodipine and additional PTA in selected cases." | 3.91 | Complication rate of intraarterial treatment of severe cerebral vasospasm after subarachnoid hemorrhage with nimodipine and percutaneous transluminal balloon angioplasty: Worth the risk? ( Adami, D; Berkefeld, J; Konczalla, J; Pfeilschifter, W; Platz, J; Wagner, M; Weidauer, S, 2019) |
| "For endovascular treatment of vasospasm after aneurysmal subarachnoid hemorrhage (aSAH), an intraarterial treatment course with the calcium channel antagonist nimodipine infused for 30 min is proposed." | 3.76 | Continuous selective intraarterial infusion of nimodipine for therapy of refractory cerebral vasospasm. ( Landscheidt, JF; Lumenta, CB; Martin, H; Rodiek, SO; Schürer, L; Wolf, S, 2010) |
| "The study evaluated the effectiveness of the combination of nimodipine and cyclosporine A vs nimodipine alone in the prevention of delayed neurologic deficit in 82 (31 plus 51) patients in whom intracranial aneurysms were clipped within 72 h after subarachnoid haemorrhage." | 3.68 | A strategy for analyzing multiple parameters with application to aneurysmal SAH patients all of them clipped but treated with and without cyclosporine. ( Andrychowski, J; Barczewska, M; Bojarski, P; Dziewiecki, C; Pastuszko, M; Ryba, M, 1993) |
| "Sixty-five patients with ruptured aneurysms were operated upon within 48 to 72 hours after subarachnoid hemorrhage (SAH) and were treated with a regimen of intra- and postoperative nimodipine for the prevention of symptomatic vasospasm." | 3.67 | Acute operation and preventive nimodipine improve outcome in patients with ruptured cerebral aneurysms. ( Auer, LM, 1984) |
| "A consecutive series of 100 individuals with aneurysmal subarachnoid hemorrhage were subjected to early aneurysm operation followed by subsequent intravenous administration of the calcium antagonist nimodipine during the critical period for symptomatic vasospasm." | 3.67 | Delayed ischemic deterioration in patients with early aneurysm operation and intravenous nimodipine. ( Brandt, L; Ljunggren, B; Messeter, K; Säveland, H, 1986) |
| "The efficacy and tolerability of the dihydropyridine calcium antagonist nimodipine (BAY e 9736) in the prophylaxis of ischemic neurological deficits after subarachnoid hemorrhage were investigated in 171 patients in an open, prospective, multicenter study." | 3.67 | Clinical experience with nimodipine in the prophylaxis of neurological deficits after subarachnoid hemorrhage. ( Adelt, D; Ammerer, HP; Baumann, H; Böker, DK; Grotenhuis, JA; Istaitih, AR; Jaksche, H; Karnick, R; Kazner, E; Sprung, C, 1985) |
| "Intravenous Nimodipine was administered to 109 patients (65 female and 44 male) with either pre- or post-operative progressive neurological deterioration from cerebral vasospasm following subarachnoid hemorrhage from a ruptured aneurysm." | 3.67 | Nimodipine treatment of ischemic neurological deficits due to cerebral vasospasm after subarachnoid hemorrhage. Clinical results of a multicenter study. ( Auer, LM; Böker, DK; Gaab, M; Jaksche, H; Koos, WT; Kostron, H; Meinig, G; Muizelaar, JP; Perneczky, A; van der Werf, AJ, 1985) |
| "Nimodipine is a clinical commonly used calcium antagonistscan lowering the apoptosis rate of hippocampal neuron to reduce the incidence of postoperative cognitive dysfunction (POCD)." | 2.84 | Effects of nimodipine on postoperative delirium in elderly under general anesthesia: A prospective, randomized, controlled clinical trial. ( Guo, YY; Huo, SP; Li, YN; Wang, L; Wang, QJ; Yin, CP; Zhang, Q, 2017) |
| "Nimodipine was given to the patients during the perioperative period." | 2.68 | Nimodipine neuroprotection in cardiac valve replacement: report of an early terminated trial. ( Coker, L; Furberg, CD; Hammon, JW; Legault, C; Rogers, AT; Stump, DA; Troost, BT; Wagenknecht, LE, 1996) |
| "The nimodipine-treated group performed better in tests of verbal fluency and visual retention, suggesting that some memory functions were preserved better in this group." | 2.67 | Effects of nimodipine on cerebral blood flow and neuropsychological outcome after cardiac surgery. ( Forsman, M; Olsnes, BT; Semb, G; Steen, PA, 1990) |
| "Pretreatment with nimodipine reduces the incidence of POCD by decreasing CaN mediated hippocampal neuroapoptosis in aged rats." | 1.48 | Pretreatment with nimodipine reduces incidence of POCD by decreasing calcineurin mediated hippocampal neuroapoptosis in aged rats. ( Bao, Y; Gao, F; Guo, Y; Huo, S; Li, Y; Wang, Q; Wang, X; Xin, X; Yin, C; Zhang, Q, 2018) |
| "A consecutive series of 37 patients with vestibular schwannoma treated with nimodipine from the day before surgery until the seventh postoperative day was analyzed retrospectively." | 1.40 | Neuroprotective efficacy of prophylactic enteral and parenteral nimodipine treatment in vestibular schwannoma surgery: a comparative study. ( Herzfeld, E; Koman, G; Prell, J; Rachinger, J; Rampp, S; Scheller, C; Scheller, K; Simmermacher, S; Strauss, C; Wienke, A; Wurm, F, 2014) |
| "Diffuse cerebral vasospasm is a rare complication following tumour resection." | 1.40 | Diffuse cerebral vasospasm following resection of a hypoglossal schwannoma in a child. ( Afshari, FT; Fernandes, HM; Fitzgerald, JJ; Garnett, MR; Higgins, JN; Santarius, T, 2014) |
| "During the following 2 weeks, the cerebral vasospasm resolved with application of high-dose methyl prednisolone and nimodipine." | 1.32 | [Cerebral vasospasms with hemodynamic infarctions as a complication of HELLP syndrome]. ( Bloos, G; Harscher, S; Möller, U; Pfleiderer, SO; Terborg, C; Witte, OW, 2003) |
| "The delayed onset of a facial paresis following termination of vasoactive treatment points to a disturbed microcirculation of the nerve as the main pathophysiological feature." | 1.32 | Delayed facial nerve paresis following acoustic neuroma resection and postoperative vasoactive treatment. ( Fahlbusch, R; Romstöck, J; Scheller, C; Strauss, C, 2004) |
| "Nimodipine infusion was started before surgery." | 1.29 | Causes of morbidity and mortality after ruptured aneurysm surgery in a series of 230 patients. The importance of control angiography. ( Creissard, P; Freger, P; Hannequin, D; Langlois, O; Proust, F, 1995) |
| "Nimodipine was administered in 231 (84%) of the 275 patients." | 1.29 | Which are the major determinants for outcome in aneurysmal subarachnoid hemorrhage? A prospective total management study from a strictly unselected series. ( Brandt, L; Säveland, H, 1994) |
| "As soon as the subarachnoid hemorrhage diagnosis is confirmed by computed tomography (or if unconfirmed, by lumbar puncture), we assume that each patient may have an aneurysm." | 1.29 | Are the calcium antagonists really useful in cerebral aneurysmal surgery? A retrospective study. ( Alhayek, G; Fournier, D; Guy, G; Menei, P; Mercier, P; Rizk, T, 1994) |
| "Nimodipine treatment was started within three days of delayed ischaemic deficit (DID) onset, at a low dose increased quickly to 30-45 ug/kg/hr, and reduced gradually over the last day or two of the course." | 1.29 | Treatment of symptomatic vasospasm with nimodipine. ( Compton, JS; Dorsch, NW, 1993) |
| "Early hydrocephalus is a risk factor of shunt-dependent late hydrocephalus (SDHC)." | 1.29 | Shunt-dependent hydrocephalus after subarachnoid haemorrhage and aneurysm surgery: timing of surgery is not a risk factor. ( Hernesniemi, J; Kari, A; Luukkonen, M; Niskanen, M; Puranen, M; Tapaninaho, A; Vapalahti, M, 1993) |
| "Among the 141 patients with subarachnoid hemorrhage but not intracerebral or intraventricular hematoma, 16 made an unfavorable outcome, ie, 11% versus 56% among patients with intracerebral hematoma/intraventricular hematoma on preoperative computed tomography scan." | 1.28 | Unfavorable outcome following early surgical repair of ruptured cerebral aneurysms--a critical review of 238 patients. ( Auer, LM, 1991) |
| "The postoperative intracerebral hemorrhage occurred in 16 cases and seemed to be caused by one or more of the following events: cerebral infarction developed during the preoperative period, occlusion of the cerebral veins during the Sylvian dissection, cerebral retraction and/or sudden change of intracranial hemodynamics." | 1.28 | Surgery of intracranial aneurysms at Yonsei University: 780 cases. ( Lee, KC, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (25.00) | 18.7374 |
| 1990's | 24 (37.50) | 18.2507 |
| 2000's | 7 (10.94) | 29.6817 |
| 2010's | 15 (23.44) | 24.3611 |
| 2020's | 2 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Tian, W | 1 |
| Meng, X | 1 |
| Zou, J | 1 |
| Scheller, C | 5 |
| Strauss, C | 6 |
| Leisz, S | 1 |
| Hänel, P | 1 |
| Klemm, A | 1 |
| Kowoll, S | 1 |
| Böselt, I | 1 |
| Rahne, T | 1 |
| Wienke, A | 3 |
| Li, YN | 1 |
| Zhang, Q | 2 |
| Yin, CP | 1 |
| Guo, YY | 1 |
| Huo, SP | 1 |
| Wang, L | 1 |
| Wang, QJ | 1 |
| Lawton, MT | 1 |
| Vates, GE | 1 |
| Li, Y | 1 |
| Bao, Y | 1 |
| Yin, C | 1 |
| Xin, X | 1 |
| Guo, Y | 1 |
| Gao, F | 1 |
| Huo, S | 1 |
| Wang, X | 1 |
| Wang, Q | 1 |
| Adami, D | 1 |
| Berkefeld, J | 1 |
| Platz, J | 1 |
| Konczalla, J | 1 |
| Pfeilschifter, W | 1 |
| Weidauer, S | 1 |
| Wagner, M | 1 |
| Simonato, D | 1 |
| Gabrieli, JD | 1 |
| Cester, G | 1 |
| Della Puppa, A | 1 |
| Causin, F | 1 |
| Wurm, F | 1 |
| Simmermacher, S | 1 |
| Rampp, S | 1 |
| Prell, J | 1 |
| Rachinger, J | 1 |
| Scheller, K | 2 |
| Koman, G | 1 |
| Herzfeld, E | 1 |
| Afshari, FT | 1 |
| Fitzgerald, JJ | 1 |
| Higgins, JN | 1 |
| Garnett, MR | 1 |
| Fernandes, HM | 1 |
| Santarius, T | 1 |
| Tatagiba, M | 1 |
| Gharabaghi, A | 1 |
| Ramina, KF | 1 |
| Ganslandt, O | 1 |
| Bischoff, B | 3 |
| Zenk, J | 1 |
| Engelhorn, T | 1 |
| Matthies, C | 1 |
| Westermaier, T | 1 |
| Antoniadis, G | 1 |
| Pedro, MT | 1 |
| Rohde, V | 1 |
| von Eckardstein, K | 1 |
| Kretschmer, T | 1 |
| Kornhuber, M | 1 |
| Steighardt, J | 1 |
| Richter, M | 1 |
| Barker, FG | 1 |
| Kerz, T | 1 |
| Boor, S | 1 |
| Ulrich, A | 1 |
| Beyer, C | 1 |
| Hechtner, M | 1 |
| Mueller-Forell, W | 1 |
| Sundararajan, K | 1 |
| Roberts-Thomson, RL | 1 |
| Nelson, AJ | 1 |
| Psaltis, PJ | 1 |
| Youssef, AS | 1 |
| Downes, AE | 1 |
| Wolf, S | 1 |
| Martin, H | 1 |
| Landscheidt, JF | 1 |
| Rodiek, SO | 1 |
| Schürer, L | 1 |
| Lumenta, CB | 1 |
| Webb, AJ | 1 |
| Gillies, MJ | 1 |
| Cadoux-Hudson, TA | 1 |
| Spiriev, T | 1 |
| Kondoff, S | 1 |
| Schaller, B | 1 |
| Chalouhi, N | 1 |
| Jabbour, P | 1 |
| Ibrahim, I | 1 |
| Starke, RM | 1 |
| Younes, P | 1 |
| El Hage, G | 1 |
| Samaha, E | 1 |
| Macdonald, RL | 1 |
| Rosengart, A | 1 |
| Huo, D | 1 |
| Karrison, T | 1 |
| Harscher, S | 1 |
| Witte, OW | 1 |
| Möller, U | 1 |
| Bloos, G | 1 |
| Pfleiderer, SO | 1 |
| Terborg, C | 1 |
| Fahlbusch, R | 3 |
| Romstöck, J | 3 |
| Buchfelder, M | 1 |
| Auer, LM | 4 |
| Ljunggren, B | 4 |
| Brandt, L | 6 |
| Säveland, H | 5 |
| Nilsson, PE | 1 |
| Cronqvist, S | 1 |
| Andersson, KE | 2 |
| Vinge, E | 1 |
| Trembly, B | 1 |
| Proust, F | 1 |
| Hannequin, D | 1 |
| Langlois, O | 1 |
| Freger, P | 2 |
| Creissard, P | 2 |
| Mercier, P | 1 |
| Alhayek, G | 1 |
| Rizk, T | 1 |
| Fournier, D | 1 |
| Menei, P | 1 |
| Guy, G | 1 |
| Hütter, BO | 1 |
| Gilsbach, JM | 4 |
| Dorsch, NW | 1 |
| Compton, JS | 1 |
| Tapaninaho, A | 1 |
| Hernesniemi, J | 1 |
| Vapalahti, M | 1 |
| Niskanen, M | 1 |
| Kari, A | 1 |
| Luukkonen, M | 1 |
| Puranen, M | 1 |
| Seifert, V | 1 |
| Ryba, M | 1 |
| Pastuszko, M | 1 |
| Dziewiecki, C | 1 |
| Andrychowski, J | 1 |
| Bojarski, P | 1 |
| Barczewska, M | 1 |
| Legault, C | 1 |
| Furberg, CD | 1 |
| Wagenknecht, LE | 1 |
| Rogers, AT | 1 |
| Stump, DA | 1 |
| Coker, L | 1 |
| Troost, BT | 1 |
| Hammon, JW | 1 |
| Mathiesen, T | 1 |
| Kakarieka, A | 1 |
| Edner, G | 1 |
| Duan, A | 1 |
| Ding, Y | 1 |
| Hua, Y | 1 |
| Morgan, MK | 1 |
| Sekhon, LH | 1 |
| Finfer, S | 1 |
| Grinnell, V | 1 |
| Karinen, P | 1 |
| Koivukangas, P | 1 |
| Ohinmaa, A | 1 |
| Koivukangas, J | 2 |
| Ohman, J | 1 |
| Neu, M | 1 |
| Berg, M | 1 |
| Matula, C | 1 |
| Schoeggl, A | 1 |
| Origitano, TC | 1 |
| Reichman, OH | 1 |
| Anderson, DE | 1 |
| Vilkki, J | 1 |
| Stewart, DP | 1 |
| McInnes, A | 1 |
| Martin, RW | 1 |
| Fulton, JD | 1 |
| Romner, B | 2 |
| Ryman, T | 2 |
| Lee, KC | 1 |
| Bracard, S | 1 |
| Picard, L | 1 |
| Marchal, JC | 1 |
| Ducrocq, X | 1 |
| Per, A | 1 |
| Czorny, A | 1 |
| Islak, C | 1 |
| Roy, D | 1 |
| Roland, J | 1 |
| Lepoire, J | 1 |
| Forsman, M | 1 |
| Olsnes, BT | 1 |
| Semb, G | 1 |
| Steen, PA | 1 |
| Wroński, J | 1 |
| Abraszko, R | 1 |
| Berny, W | 1 |
| Mierzwa, J | 1 |
| Rabehenoina, C | 1 |
| Sevrain, L | 1 |
| Hattab, N | 1 |
| Tadie, M | 1 |
| Clavier, E | 1 |
| Thiebot, J | 1 |
| Laissy, JP | 1 |
| Harders, AG | 2 |
| Kostron, H | 2 |
| Twerdy, K | 1 |
| Grunert, V | 1 |
| Mehdorn, HM | 1 |
| Hoffmann, B | 1 |
| Ackermann, L | 1 |
| Grupe, H | 1 |
| Feldges, A | 1 |
| Mee, E | 1 |
| Dorrance, D | 1 |
| Lowe, D | 1 |
| Neil-Dwyer, G | 1 |
| Eggert, HR | 1 |
| Hornyak, ME | 1 |
| Messeter, K | 2 |
| Algotsson, L | 1 |
| Ryding, E | 1 |
| Tucker, WS | 1 |
| Heikkinen, ER | 1 |
| Harders, A | 1 |
| Kazner, E | 1 |
| Sprung, C | 1 |
| Adelt, D | 1 |
| Ammerer, HP | 1 |
| Karnick, R | 1 |
| Baumann, H | 1 |
| Böker, DK | 2 |
| Grotenhuis, JA | 1 |
| Jaksche, H | 2 |
| Istaitih, AR | 1 |
| Koos, WT | 1 |
| Perneczky, A | 1 |
| Gaab, M | 1 |
| Meinig, G | 1 |
| Muizelaar, JP | 1 |
| van der Werf, AJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Anesthetic Method and Cerebral Outcomes: A Prospective Randomized Controlled Trial.[NCT03696719] | 140 participants (Anticipated) | Interventional | 2018-11-01 | Active, not recruiting | |||
| An Evaluation of Effectiveness and Safety of the CorPath® GRX System in Endovascular Embolization Procedures of Cerebral Aneurysms[NCT04236856] | 120 participants (Actual) | Interventional | 2020-08-21 | Completed | |||
| MRI Evaluation of Nidus Occlusion After Gamma Knife Radiosurgery of Cerebral Arteriovenous Malformations - A Prospective Preliminary Study[NCT03995823] | 50 participants (Anticipated) | Observational | 2019-07-01 | Recruiting | |||
| Neuroprotective Effect of Dapsone in Patients With Aneurysmal Subarachnoid Hemorrhage: Prospective, Randomized, Double-Blinded, Placebo-Controlled, Clinical Trial[NCT05131295] | Phase 3 | 49 participants (Actual) | Interventional | 2007-09-05 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for nimodipine and Complication, Postoperative
| Article | Year |
|---|---|
Subarachnoid Hemorrhage.
Topics: Adolescent; Aneurysm, Ruptured; Angiography; Brain; Calcium Channel Blockers; Endovascular Procedure | 2017 |
Intraoperative neurophysiological monitoring in vestibular schwannoma surgery: advances and clinical implications.
Topics: Action Potentials; Cochlear Nerve; Electromyography; Evoked Potentials, Auditory, Brain Stem; Facial | 2009 |
Clinical potential for the use of neuroprotective agents. A brief overview.
Topics: Animals; Brain Diseases; Brain Injuries; Brain Ischemia; Calcium Channel Blockers; Cerebrovascular D | 1995 |
[Neurosurgical therapy of subarachnoid hemorrhage. Microsurgical techniques--early postoperative nimodipine administration].
Topics: Aged; Aneurysm, Ruptured; Combined Modality Therapy; Drug Administration Schedule; Humans; Intracran | 1993 |
Cerebral protection before, during and after neurosurgical procedures.
Topics: Amino Acids; Brain Damage, Chronic; Calcium Channel Blockers; Clinical Trials as Topic; Cognition Di | 2000 |
Aneurysmal subarachnoid hemorrhage: prevention of delayed ischemic dysfunction with intravenous nimodipine.
Topics: Brain Ischemia; Clinical Trials as Topic; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; | 1987 |
14 trials available for nimodipine and Complication, Postoperative
| Article | Year |
|---|---|
Prophylactic nimodipine treatment for hearing preservation after vestibular schwannoma surgery: study protocol of a randomized multi-center phase III trial-AkniPro 2.
Topics: Adult; Clinical Trials, Phase III as Topic; Hearing; Humans; Multicenter Studies as Topic; Neuroma, | 2021 |
Effects of nimodipine on postoperative delirium in elderly under general anesthesia: A prospective, randomized, controlled clinical trial.
Topics: Aged; Anesthesia, General; Blood Gas Analysis; Cerebrum; Delirium; Enzyme-Linked Immunosorbent Assay | 2017 |
Prophylactic nimodipine treatment for cochlear and facial nerve preservation after vestibular schwannoma surgery: a randomized multicenter Phase III trial.
Topics: Adult; Cochlear Nerve; Cranial Nerve Injuries; Facial Nerve; Female; Humans; Male; Middle Aged; Neur | 2016 |
Factors associated with the development of vasospasm after planned surgical treatment of aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Combined Modality Therapy; Double-Blind Method; Drug Therapy, Combination; Female; Huma | 2003 |
Nimodipine neuroprotection in cardiac valve replacement: report of an early terminated trial.
Topics: Adult; Aged; Aortic Valve; Calcium Channel Blockers; Cerebrovascular Disorders; Double-Blind Method; | 1996 |
Cost-effectiveness analysis of nimodipine treatment after aneurysmal subarachnoid hemorrhage and surgery.
Topics: Adolescent; Adult; Aged; Aneurysm, Ruptured; Combined Modality Therapy; Cost-Benefit Analysis; Doubl | 1999 |
Vasoactive treatment for hearing preservation in acoustic neuroma surgery.
Topics: Adult; Aged; Deafness; Evoked Potentials, Auditory, Brain Stem; Hearing; Humans; Hydroxyethyl Starch | 2001 |
Cognitive flexibility and mental programming after closed head injuries and anterior or posterior cerebral excisions.
Topics: Adolescent; Adult; Aged; Attention; Brain Damage, Chronic; Brain Neoplasms; Cognition Disorders; Fem | 1992 |
Effects of nimodipine on cerebral blood flow and neuropsychological outcome after cardiac surgery.
Topics: Brain; Brain Ischemia; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cerebrovascular Circulat | 1990 |
[Therapy of aneurysm-induced subarachnoid hemorrhage].
Topics: Follow-Up Studies; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Nimodipine; Postoperat | 1988 |
Controlled study of nimodipine in aneurysm patients treated early after subarachnoid hemorrhage.
Topics: Adolescent; Adult; Aged; Cardiovascular System; Cerebrovascular Circulation; Clinical Trials as Topi | 1988 |
Aneurysmal subarachnoid hemorrhage: prevention of delayed ischemic dysfunction with intravenous nimodipine.
Topics: Brain Ischemia; Clinical Trials as Topic; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; | 1987 |
The relationship between timing of surgery and operative complications in aneurysmal subarachnoid hemorrhage.
Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Intracranial Aneurysm; Middle Aged; Nimodipin | 1987 |
Preventive nimodipine and acute aneurysm surgery. Heading for the control of complications after aneurysmal subarachnoid hemorrhage.
Topics: Animals; Arteries; Brain Ischemia; Calcium Channel Blockers; Cats; Cerebral Revascularization; Clini | 1985 |
45 other studies available for nimodipine and Complication, Postoperative
| Article | Year |
|---|---|
Delayed Facial Palsy after Microvascular Decompression for Trigeminal Neuralgia.
Topics: Acyclovir; Aged; Drug Therapy, Combination; Facial Paralysis; Humans; Male; Methylprednisolone; Micr | 2020 |
Pretreatment with nimodipine reduces incidence of POCD by decreasing calcineurin mediated hippocampal neuroapoptosis in aged rats.
Topics: Aging; Animals; Apoptosis; Calcineurin; Calcium Channel Blockers; Cognition Disorders; Disease Model | 2018 |
Complication rate of intraarterial treatment of severe cerebral vasospasm after subarachnoid hemorrhage with nimodipine and percutaneous transluminal balloon angioplasty: Worth the risk?
Topics: Adult; Aged; Angioplasty; Aortic Dissection; Cerebral Infarction; Combined Modality Therapy; Female; | 2019 |
Intracranial stenting after tumor exeresis complicated by delayed kinking of the middle cerebral artery.
Topics: Aged; Cerebral Revascularization; Humans; Male; Meningeal Neoplasms; Meningioma; Middle Cerebral Art | 2019 |
Neuroprotective efficacy of prophylactic enteral and parenteral nimodipine treatment in vestibular schwannoma surgery: a comparative study.
Topics: Adult; Aged; Aged, 80 and over; Cochlear Nerve; Facial Nerve; Female; Humans; Male; Middle Aged; Neu | 2014 |
Diffuse cerebral vasospasm following resection of a hypoglossal schwannoma in a child.
Topics: Cerebral Angiography; Child; Cranial Nerve Neoplasms; Female; Humans; Milrinone; Neurilemmoma; Nimod | 2014 |
Endovascular therapy for vasospasm after aneurysmatic subarachnoid hemorrhage.
Topics: Adult; Aged; Angioplasty, Balloon; Cerebral Arteries; Endovascular Procedures; Female; Humans; Injec | 2016 |
Therapeutic paradox: nimodipine attenuates severe coronary spasm following coronary artery graft surgery in a high-risk vasoplegic cancer patient.
Topics: Colorectal Neoplasms; Coronary Angiography; Coronary Artery Bypass; Coronary Vasospasm; Coronary Ves | 2017 |
Continuous selective intraarterial infusion of nimodipine for therapy of refractory cerebral vasospasm.
Topics: Adult; Anticoagulants; Calcium Channel Blockers; Cerebral Angiography; Drug Therapy, Combination; Em | 2010 |
Acute vasospasm following transcallosal resection of a xanthogranulomatous colloid cyst of the 3rd ventricle.
Topics: Angioplasty; Calcium Channel Blockers; Central Nervous System Cysts; Cerebral Angiography; Cerebral | 2010 |
Nimodipine promotes regeneration of peripheral facial nerve function after traumatic injury following maxillofacial surgery: an off label pilot-study.
Topics: Adolescent; Adult; Aged; Facial Bones; Facial Nerve; Facial Nerve Injuries; Facial Paralysis; Female | 2012 |
Cardiovascular changes after subarachnoid hemorrhage initiated by the trigeminocardiac reflex-first description of a case series.
Topics: Antihypertensive Agents; Blood Pressure; Female; Heart Rate; Hemodynamics; Humans; Intracranial Pres | 2011 |
Surgical treatment of ruptured anterior circulation aneurysms: comparison of pterional and supraorbital keyhole approaches.
Topics: Anesthesia, General; Aneurysm, Ruptured; Calcium Channel Blockers; Female; Glasgow Outcome Scale; Hu | 2013 |
[Cerebral vasospasms with hemodynamic infarctions as a complication of HELLP syndrome].
Topics: Adult; Cesarean Section; Diagnostic Imaging; Dose-Response Relationship, Drug; Female; Follow-Up Stu | 2003 |
Delayed facial nerve paresis following acoustic neuroma resection and postoperative vasoactive treatment.
Topics: Adult; Electric Stimulation; Electromyography; Facial Nerve Diseases; Facial Paralysis; Female; Huma | 2004 |
Intraoperative brainstem auditory evoked potential pattern and perioperative vasoactive treatment for hearing preservation in vestibular schwannoma surgery.
Topics: Adult; Brain Stem; Cochlear Nerve; Deafness; Evoked Potentials, Auditory, Brain Stem; Female; Follow | 2008 |
Acute operation and preventive nimodipine improve outcome in patients with ruptured cerebral aneurysms.
Topics: Adult; Female; Follow-Up Studies; Humans; Intracranial Aneurysm; Intraoperative Complications; Ische | 1984 |
Outcome in 60 consecutive patients treated with early aneurysm operation and intravenous nimodipine.
Topics: Adult; Combined Modality Therapy; Evaluation Studies as Topic; Female; Humans; Intracranial Aneurysm | 1984 |
Causes of morbidity and mortality after ruptured aneurysm surgery in a series of 230 patients. The importance of control angiography.
Topics: Adolescent; Adult; Aged; Aneurysm, Ruptured; Brain Ischemia; Cerebral Angiography; Cerebral Hemorrha | 1995 |
Which are the major determinants for outcome in aneurysmal subarachnoid hemorrhage? A prospective total management study from a strictly unselected series.
Topics: Adult; Aged; Aneurysm, Ruptured; Brain Ischemia; Cause of Death; Disability Evaluation; Female; Foll | 1994 |
Are the calcium antagonists really useful in cerebral aneurysmal surgery? A retrospective study.
Topics: Activities of Daily Living; Adult; Aged; Brain Ischemia; Calcium Channel Blockers; Cerebral Angiogra | 1994 |
Which neuropsychological deficits are hidden behind a good outcome (Glasgow = I) after aneurysmal subarachnoid hemorrhage?
Topics: Adult; Age Factors; Aphasia; Cognition Disorders; Female; Follow-Up Studies; Glasgow Coma Scale; Hum | 1993 |
Treatment of symptomatic vasospasm with nimodipine.
Topics: Adolescent; Adult; Aged; Cause of Death; Female; Glasgow Coma Scale; Humans; Infusions, Intravenous; | 1993 |
Shunt-dependent hydrocephalus after subarachnoid haemorrhage and aneurysm surgery: timing of surgery is not a risk factor.
Topics: Adult; Aneurysm, Ruptured; Cerebrospinal Fluid Shunts; Combined Modality Therapy; Female; Humans; Hy | 1993 |
A strategy for analyzing multiple parameters with application to aneurysmal SAH patients all of them clipped but treated with and without cyclosporine.
Topics: Adult; Aged; Aneurysm, Ruptured; Cyclosporine; Drug Therapy, Combination; Female; Glasgow Coma Scale | 1993 |
Traumatic intracerebral lesions without extracerebral haematoma in 218 patients.
Topics: Adult; Brain Concussion; Brain Damage, Chronic; Calcium Channel Blockers; Cerebral Hemorrhage; Combi | 1995 |
[Comprehensive treatment of intracranial aneurysm complicated by postoperative vasospasm].
Topics: Adult; Aged; Calcium Channel Blockers; Combined Modality Therapy; Female; Hemodilution; Humans; Intr | 1996 |
Delayed neurological deterioration following resection of arteriovenous malformations of the brain.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Aneurysm; Anticoagulants; Antihypertensive Agents; Asp | 1999 |
Prophylactic hypervolemia without calcium channel blockers in early aneurysm surgery.
Topics: Blood Volume; Brain; Hemodilution; Humans; Intracranial Aneurysm; Nimodipine; Postoperative Complica | 1992 |
Association of migrainous headaches with Gasserian ganglial ablation.
Topics: Aged; Confusion; Drug Therapy, Combination; Humans; Male; Migraine Disorders; Nimodipine; Pizotyline | 1992 |
Does nimodipine eliminate arterial hypertension as a prognostic risk factor in subarachnoid haemorrhage?
Topics: Adolescent; Adult; Aged; Female; Humans; Hypertension; Intracranial Aneurysm; Ischemic Attack, Trans | 1991 |
Unfavorable outcome following early surgical repair of ruptured cerebral aneurysms--a critical review of 238 patients.
Topics: Aged; Cerebral Hemorrhage; Female; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Male; | 1991 |
Surgery of intracranial aneurysms at Yonsei University: 780 cases.
Topics: Brain Ischemia; Cerebral Hemorrhage; Humans; Hydrocephalus; Intracranial Aneurysm; Nimodipine; Posto | 1991 |
Role of angioplasty in the treatment of symptomatic vascular spasm occurring in the post-operative course of intracranial ruptured aneurysms.
Topics: Adult; Angiography; Angioplasty, Balloon; Circle of Willis; Female; Humans; Intracranial Aneurysm; I | 1990 |
Clinical experiences with nimodipine treatment in patients after SAH and aneurysm surgery.
Topics: Adolescent; Adult; Aged; Female; Humans; Infusions, Intravenous; Intracranial Aneurysm; Ischemic Att | 1990 |
[The value of a computer tomography scanner and controlled arteriography in the study of the results of aneurysm surgery. A series of 100 consecutive cases].
Topics: Adult; Aged; Aneurysm; Angiography; Carotid Artery Diseases; Cerebral Angiography; Cerebral Hemorrha | 1990 |
Morbidity and mortality after early aneurysm surgery--a prospective study with nimodipine prevention.
Topics: Adult; Aged; Brain Ischemia; Cerebral Arteries; Cerebral Hemorrhage; Cerebral Infarction; Combined M | 1989 |
The calcium entry blocker nimodipine improves the quality of life of patients operated on for cerebral aneurysms. A 5-year follow-up analysis.
Topics: Activities of Daily Living; Adolescent; Adult; Aged; Female; Follow-Up Studies; Humans; Infusions, I | 1988 |
Early aneurysm surgery: a 7 year clinical practice report.
Topics: Cerebral Angiography; Cerebrospinal Fluid Shunts; Humans; Hydrocephalus; Intracranial Aneurysm; Isch | 1988 |
Prediction and prevention of delayed ischemic dysfunction in early aneurysm surgery.
Topics: Adult; Brain Ischemia; Cerebrovascular Circulation; Female; Humans; Hyperventilation; Intracranial A | 1987 |
Surgery of vertebrobasilar aneurysms and nimodipine.
Topics: Adult; Aneurysm; Basilar Artery; Cerebral Angiography; Female; Humans; Ischemic Attack, Transient; M | 1986 |
Early aneurysm operation and vasospasm. Intracranial Doppler findings.
Topics: Adult; Calcium Channel Blockers; Circle of Willis; Female; Humans; Intracranial Aneurysm; Ischemic A | 1985 |
Delayed ischemic deterioration in patients with early aneurysm operation and intravenous nimodipine.
Topics: Brain Ischemia; Carotid Artery Diseases; Carotid Artery, Internal; Cerebral Arterial Diseases; Combi | 1986 |
Clinical experience with nimodipine in the prophylaxis of neurological deficits after subarachnoid hemorrhage.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Intracran | 1985 |
Nimodipine treatment of ischemic neurological deficits due to cerebral vasospasm after subarachnoid hemorrhage. Clinical results of a multicenter study.
Topics: Adult; Aged; Brain Ischemia; Drug Interactions; Female; Humans; Intracranial Aneurysm; Ischemic Atta | 1985 |