Page last updated: 2024-11-01

nimodipine and Cirrhosis, Liver

nimodipine has been researched along with Cirrhosis, Liver in 2 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Research Excerpts

ExcerptRelevanceReference
"Liver fibrosis is the principal cause of morbidity and mortality in patients with iron overload."1.43Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis. ( Chang, Y; Chu, L; Chu, X; Gao, Y; Guo, H; Liu, Z; Wang, N; Zhang, J; Zhang, X; Zhang, Y; Zhao, X, 2016)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, Y2
Zhao, X1
Chang, Y1
Chu, X1
Zhang, X1
Liu, Z1
Guo, H1
Wang, N1
Gao, Y1
Zhang, J1
Chu, L1
Gengo, FM1
Fagan, SC1
Krol, G1
Bernhard, H1

Trials

1 trial available for nimodipine and Cirrhosis, Liver

ArticleYear
Nimodipine disposition and haemodynamic effects in patients with cirrhosis and age-matched controls.
    British journal of clinical pharmacology, 1987, Volume: 23, Issue:1

    Topics: Adult; Aged; Blood Pressure; Humans; Kinetics; Liver Cirrhosis; Metabolic Clearance Rate; Middle Age

1987

Other Studies

1 other study available for nimodipine and Cirrhosis, Liver

ArticleYear
Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis.
    Toxicology and applied pharmacology, 2016, 06-15, Volume: 301

    Topics: Animals; Apoptosis; Calcium Channel Blockers; Cell Line; Collagen; Deferoxamine; Diltiazem; Hepatic

2016