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nimodipine and Central Nervous System Origin Vertigo

nimodipine has been researched along with Central Nervous System Origin Vertigo in 8 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Research Excerpts

ExcerptRelevanceReference
"There were two formulations used to assess the effectiveness in vertigo treatment from peripheral origin: nimodipine administrated three times daily (Nimotop®) 30 mg versus nimodipine AP administrated once daily (Tropocer®) 90 mg; both of them in a administrated in a prospective, randomized, double-blind, double dummy, multicenter and parallel-group study, where patients with peripheral vertigo defined as a score ≥7 on the Vertigo-Dizziness Differential Diagnosis Score were included."9.17Evaluation of the effect of nimodipine o.d. (extended release) vs nimodipine t.i.d. in the treatment of peripheral vertigo. ( Alejandro, R; Carlos, RJ; Consuelo, P; Elena, C; Glenda, C; Lisbeth, M; Maria, GY, 2013)
"There were two formulations used to assess the effectiveness in vertigo treatment from peripheral origin: nimodipine administrated three times daily (Nimotop®) 30 mg versus nimodipine AP administrated once daily (Tropocer®) 90 mg; both of them in a administrated in a prospective, randomized, double-blind, double dummy, multicenter and parallel-group study, where patients with peripheral vertigo defined as a score ≥7 on the Vertigo-Dizziness Differential Diagnosis Score were included."5.17Evaluation of the effect of nimodipine o.d. (extended release) vs nimodipine t.i.d. in the treatment of peripheral vertigo. ( Alejandro, R; Carlos, RJ; Consuelo, P; Elena, C; Glenda, C; Lisbeth, M; Maria, GY, 2013)
"Eighty-three patients with CCI were randomly divided into YXQNG and nimodipine (ND) groups, the score of vertigo and the change in cerebral blood velocity before and after treatment were observed."5.11Study on Yangxue Qingnao granule in treating chronic cerebrovascular insufficiency. ( Cai, DF; Chen, YP; Gu, XX; Teng, Y; Wen, M; Yang, YK, 2005)
"Two calcium antagonists were used to treat vertigo (nimodipine, 89 patients; cinnarizine, 92 patients), and all patients were maintained on the same dosage regimen until they completed 12 weeks of treatment."5.10New approaches to the management of peripheral vertigo: efficacy and safety of two calcium antagonists in a 12-week, multinational, double-blind study. ( Abiuso, J; Alegría, J; Arenas, JE; Castañeda, JR; F, GV; Flaskamp, R; Gómez, JM; González, RH; Guerra, OJ; Hanuch, E; Hernández, J; Hidalgo, LO; Madrid, CE; Martínez, C; Morán, LM; Pedraza, A; Pianese, CP; Ponce, JE; Quijano, D; Ramírez, AM; Rubio, AT; Sanjuán, AP; Uribe, JO; Volpi, C, 2002)
"Due to its proposed vasoactive and neuroprotective effects, nimodipine may play a role in the treatment of a number of otolaryngic pathologies including VS, Ménière's disease, peripheral vertigo, RLN injury, and facial weakness after maxillofacial surgery."4.98Nimodipine for the treatment of otolaryngic indications. ( Levy, ZD; Shafeeq, H; Sin, JH, 2018)
"An animal experimental model of vertebrobasilar insufficiency was developed."2.66Calcium entry blockers in the treatment of vertebrobasilar insufficiency. ( Hofferberth, B, 1986)
"Vertebrobasilar insufficiency (VBI) is a clinical syndrome which includes different transient brain stem symptoms."2.65[Calcium blockers in the therapy of vertebrobasilar insufficiency. Results of animal experiments and clinical studies]. ( Hofferberth, B, 1984)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sin, JH1
Shafeeq, H1
Levy, ZD1
Wu, C1
Liao, L1
Yan, X1
Li, M1
Wu, S1
Wang, J1
Lin, J1
Li, S1
Gao, L1
DU, J1
Yang, R1
Lisbeth, M1
Consuelo, P1
Glenda, C1
Elena, C1
Carlos, RJ1
Alejandro, R1
Maria, GY1
Monzani, D1
Genovese, E1
Pini, LA1
Di Berardino, F1
Alicandri Ciufelli, M1
Galeazzi, GM1
Presutti, L1
Gu, XX1
Cai, DF1
Yang, YK1
Teng, Y1
Chen, YP1
Wen, M1
Hofferberth, B2
Pianese, CP1
Hidalgo, LO1
González, RH1
Madrid, CE1
Ponce, JE1
Ramírez, AM1
Morán, LM1
Arenas, JE1
Rubio, AT1
Uribe, JO1
Abiuso, J1
Hanuch, E1
Alegría, J1
Volpi, C1
Flaskamp, R1
Sanjuán, AP1
Gómez, JM1
Hernández, J1
Pedraza, A1
Quijano, D1
Martínez, C1
Castañeda, JR1
Guerra, OJ1
F, GV1

Reviews

2 reviews available for nimodipine and Central Nervous System Origin Vertigo

ArticleYear
Nimodipine for the treatment of otolaryngic indications.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2018, Sep-15, Volume: 75, Issue:18

    Topics: Calcium Channel Blockers; Humans; Meniere Disease; Neuroprotective Agents; Nimodipine; Otorhinolaryn

2018
Nimodipine in otolaryngology: from past evidence to clinical perspectives.
    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2015, Volume: 35, Issue:3

    Topics: Calcium Channel Blockers; Humans; Migraine Disorders; Nimodipine; Otorhinolaryngologic Diseases; Ver

2015

Trials

6 trials available for nimodipine and Central Nervous System Origin Vertigo

ArticleYear
Effects of Yangxue Qingnao Granules on chronic cerebral circulation insufficiency: a randomized, double-blind, double-dummy, controlled multicentre trial.
    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2013, Volume: 13, Issue:1

    Topics: Adult; Cerebrovascular Circulation; China; Dizziness; Dose-Response Relationship, Drug; Double-Blind

2013
Evaluation of the effect of nimodipine o.d. (extended release) vs nimodipine t.i.d. in the treatment of peripheral vertigo.
    Current drug delivery, 2013, Volume: 10, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Calcium Channel Blockers; Delayed-Action Preparations; Double-Blind

2013
Study on Yangxue Qingnao granule in treating chronic cerebrovascular insufficiency.
    Chinese journal of integrative medicine, 2005, Volume: 11, Issue:1

    Topics: Aged; Aged, 80 and over; Animals; Blood Flow Velocity; Cerebrovascular Circulation; Cerebrovascular

2005
[Calcium blockers in the therapy of vertebrobasilar insufficiency. Results of animal experiments and clinical studies].
    Fortschritte der Medizin, 1984, Jul-26, Volume: 102, Issue:27-28

    Topics: Animals; Calcium Channel Blockers; Cerebrovascular Circulation; Cinnarizine; Clinical Trials as Topi

1984
New approaches to the management of peripheral vertigo: efficacy and safety of two calcium antagonists in a 12-week, multinational, double-blind study.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2002, Volume: 23, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Calcium Channel Blockers; Cinnarizine; Drug Administration Schedule;

2002
Calcium entry blockers in the treatment of vertebrobasilar insufficiency.
    European neurology, 1986, Volume: 25 Suppl 1

    Topics: Animals; Clinical Trials as Topic; Dogs; Flunarizine; Humans; Nimodipine; Nystagmus, Pathologic; Pen

1986