nimodipine has been researched along with Central Nervous System Disease in 6 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nimodipine has no consistent effect on brain oxygen consumption or cortical ATP or phosphocreatine levels, although the ischemia-induced fall of brain ATP levels in gerbils or the lowering of intracellular brain pH in rabbits with focal cerebral ischemia were antagonized by the drug." | 2.38 | Pharmacological basis for the use of nimodipine in central nervous system disorders. ( Schuurman, T; Scriabine, A; Traber, J, 1989) |
| "Nimodipine (Nimotop) was administered to spontaneously hypertensive rats (SHR) in order to investigate its ameliorative effect on central nervous disorders associated with hypertension." | 1.27 | Effect of nimodipine on brightness discrimination learning test in Wistar Kyoto and spontaneously hypertensive rats. ( Nomura, M, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tateishi, A | 2 |
| Scheller, MS | 2 |
| Drummond, JC | 2 |
| Zornow, MH | 2 |
| Grafe, MR | 2 |
| Fleischer, JE | 2 |
| Shapiro, HM | 2 |
| Calle, PA | 1 |
| Bogaert, MG | 1 |
| De Ridder, L | 1 |
| Buylaert, WA | 1 |
| Scriabine, A | 1 |
| Schuurman, T | 1 |
| Traber, J | 1 |
| Nomura, M | 1 |
1 review available for nimodipine and Central Nervous System Disease
| Article | Year |
|---|---|
Pharmacological basis for the use of nimodipine in central nervous system disorders.
Topics: Aging; Animals; Anticonvulsants; Behavior, Animal; Brain; Brain Damage, Chronic; Brain Ischemia; Cen | 1989 |
5 other studies available for nimodipine and Central Nervous System Disease
| Article | Year |
|---|---|
Failure of nimodipine to improve neurologic outcome after eighteen minutes of cardiac arrest in the cat.
Topics: Animals; Cats; Central Nervous System Diseases; Electroencephalography; Heart Arrest; Hemodynamics; | 1991 |
Nimodipine decreases resuscitability in a cardiopulmonary arrest model in the rat.
Topics: Animals; Central Nervous System Diseases; Heart Arrest; Nimodipine; Rats; Rats, Inbred Strains; Resu | 1991 |
[Drug for the control of stroke may help AIDS patients].
Topics: Acquired Immunodeficiency Syndrome; Central Nervous System Diseases; Humans; Nimodipine | 1990 |
Nimodipine does not improve neurologic outcome after 14 minutes of cardiac arrest in cats.
Topics: Animals; Brain; Cats; Central Nervous System Diseases; Electroencephalography; Heart Arrest; Nimodip | 1989 |
Effect of nimodipine on brightness discrimination learning test in Wistar Kyoto and spontaneously hypertensive rats.
Topics: Animals; Behavior, Animal; Blood Pressure; Central Nervous System Diseases; Discrimination Learning; | 1988 |