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nimodipine and Carotid Artery Diseases

nimodipine has been researched along with Carotid Artery Diseases in 7 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Carotid Artery Diseases: Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.

Research Excerpts

ExcerptRelevanceReference
"In patients with aneurysmal subarachnoid hemorrhage (SAH), delayed ischemic cerebral dysfunction (DID or symptomatic vasospasm) with subsequent fixed neurological dysfunction (FND) is a frequent and most feared complication induced by the hemorrhage."6.66Cerebral vasospasm and calcium channel blockade. Nimodipine treatment in patients with aneurysmal subarachnoid hemorrhage. ( Andersson, KE; Brandt, L; Ljunggren, B; Säveland, H; Vinge, E, 1986)
"Based on the outcomes of surgical management of thirty-six patients diagnosed with atherosclerosis of carotid arteries and a further thirty-five 35 patients presenting with atherosclerotic lesions of the subclavian and vertebral arteries the authors substantiated a differentiated therapeutic policy aimed at protecting the brain from ischaemia, having demonstrated efficiency of cerebral protection with nimodipine and rheopolyglukin in patients subjected to operations on the subclavian and vertebral arteries and feasibility of combining this method with the application of a temporary puncture carotid-artery bypass graft during carotid endarterectomy."3.76[A combined method to protect the brain during operations on the brachiocephalic arteries]. ( Gubenko, AV; Loenko, VB; Smialovskiĭ, VE; Sorokina, EA, 2010)
"A consecutive series of 100 individuals with aneurysmal subarachnoid hemorrhage were subjected to early aneurysm operation followed by subsequent intravenous administration of the calcium antagonist nimodipine during the critical period for symptomatic vasospasm."3.67Delayed ischemic deterioration in patients with early aneurysm operation and intravenous nimodipine. ( Brandt, L; Ljunggren, B; Messeter, K; Säveland, H, 1986)
"In patients with aneurysmal subarachnoid hemorrhage (SAH), delayed ischemic cerebral dysfunction (DID or symptomatic vasospasm) with subsequent fixed neurological dysfunction (FND) is a frequent and most feared complication induced by the hemorrhage."2.66Cerebral vasospasm and calcium channel blockade. Nimodipine treatment in patients with aneurysmal subarachnoid hemorrhage. ( Andersson, KE; Brandt, L; Ljunggren, B; Säveland, H; Vinge, E, 1986)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hu, M1
Liu, Z1
Lv, P1
Wang, H1
Zhu, Y1
Qi, Q1
Xu, J1
Gao, L1
Konczalla, J1
Brawanski, N1
Platz, J1
Senft, C1
Kashefiolasl, S1
Seifert, V1
Loenko, VB1
Sorokina, EA1
Smialovskiĭ, VE1
Gubenko, AV1
Creissard, P1
Rabehenoina, C1
Sevrain, L1
Freger, P1
Hattab, N1
Tadie, M1
Clavier, E1
Thiebot, J1
Laissy, JP1
Kamei, K1
Tsuchida, S1
Nishikibe, M1
Brandt, L2
Ljunggren, B2
Säveland, H2
Andersson, KE1
Vinge, E1
Messeter, K1

Trials

1 trial available for nimodipine and Carotid Artery Diseases

ArticleYear
Cerebral vasospasm and calcium channel blockade. Nimodipine treatment in patients with aneurysmal subarachnoid hemorrhage.
    Acta pharmacologica et toxicologica, 1986, Volume: 58 Suppl 2

    Topics: Brain Ischemia; Carotid Artery Diseases; Carotid Artery, Internal; Clinical Trials as Topic; Humans;

1986

Other Studies

6 other studies available for nimodipine and Carotid Artery Diseases

ArticleYear
Nimodipine activates neuroprotective signaling events and inactivates autophages in the VCID rat hippocampus.
    Neurological research, 2017, Volume: 39, Issue:10

    Topics: Animals; Autophagy; Carotid Artery Diseases; Carotid Artery, Common; Cognitive Dysfunction; Cyclic A

2017
Aneurysm Location as a Prognostic Outcome Factor After Subarachnoid Hemorrhage From Internal Carotid Artery Aneurysms and Potential Impact for Further Experimental Subarachnoid Hemorrhage Models.
    World neurosurgery, 2016, Volume: 92

    Topics: Adult; Aged; Aneurysm, Ruptured; Carotid Artery Diseases; Female; Humans; Male; Middle Aged; Multiva

2016
[A combined method to protect the brain during operations on the brachiocephalic arteries].
    Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2010, Volume: 16, Issue:1

    Topics: Aged; Anticoagulants; Atherosclerosis; Brachiocephalic Trunk; Brain Ischemia; Carotid Artery Disease

2010
[The value of a computer tomography scanner and controlled arteriography in the study of the results of aneurysm surgery. A series of 100 consecutive cases].
    Neuro-Chirurgie, 1990, Volume: 36, Issue:4

    Topics: Adult; Aged; Aneurysm; Angiography; Carotid Artery Diseases; Cerebral Angiography; Cerebral Hemorrha

1990
[Effects of NB-818 on a transient bilateral common carotid arteries occlusion model in Mongolian gerbils].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1989, Volume: 93, Issue:6

    Topics: Animals; Arterial Occlusive Diseases; Calcium Channel Blockers; Carotid Artery Diseases; Dihydropyri

1989
Delayed ischemic deterioration in patients with early aneurysm operation and intravenous nimodipine.
    Neurosurgery, 1986, Volume: 18, Issue:2

    Topics: Brain Ischemia; Carotid Artery Diseases; Carotid Artery, Internal; Cerebral Arterial Diseases; Combi

1986