nimodipine has been researched along with Cancer of Pituitary in 12 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Maitotoxin (MTX) is a water-soluble polyether, isolated from the marine dinoflagellate Gambierdiscus toxicus, that stimulates hormone release and Ca2+ influx." | 1.28 | Maitotoxin induces a calcium-dependent membrane depolarization in GH4C1 pituitary cells via activation of type L voltage-dependent calcium channels. ( Ramsdell, JS; Van Dolah, FM; Xi, D, 1992) |
| "Pretreatment with thapsigargin blocked the ability of TRH to cause a transient increase in both [Ca2+]c and 45Ca2+ efflux." | 1.28 | Thapsigargin, but not caffeine, blocks the ability of thyrotropin-releasing hormone to release Ca2+ from an intracellular store in GH4C1 pituitary cells. ( Dannies, PS; Hanley, MR; Law, GJ; Pachter, JA; Thastrup, O, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 8 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Enyeart, JJ | 3 |
| Hinkle, PM | 5 |
| Shipston, MJ | 1 |
| Hernando, F | 1 |
| Barnard, RJ | 1 |
| Antoni, FA | 1 |
| Nilsson, CL | 1 |
| Eriksson, E | 1 |
| Levitan, ES | 1 |
| Gealy, R | 1 |
| Trimmer, JS | 1 |
| Takimoto, K | 1 |
| Pérez, FR | 1 |
| Camiña, JP | 1 |
| Zugaza, JL | 1 |
| Lage, M | 1 |
| Casabiell, X | 1 |
| Casanueva, FF | 1 |
| Li, P | 1 |
| Thaw, CN | 1 |
| Sempowski, GD | 1 |
| Gershengorn, MC | 1 |
| Shanshala, ED | 1 |
| Nelson, EJ | 1 |
| Xi, D | 1 |
| Van Dolah, FM | 1 |
| Ramsdell, JS | 1 |
| Law, GJ | 1 |
| Pachter, JA | 1 |
| Thastrup, O | 1 |
| Hanley, MR | 1 |
| Dannies, PS | 1 |
| Richardson, UI | 1 |
| Sheu, SS | 1 |
| Aizawa, T | 1 |
12 other studies available for nimodipine and Cancer of Pituitary
| Article | Year |
|---|---|
The calcium agonist Bay K 8644 stimulates secretion from a pituitary cell line.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1984 |
Glucocorticoid negative feedback in pituitary corticotropes. Pivotal role for calcineurin inhibition of adenylyl cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adrenocorticotropic Hormone; Animals; Calcimycin; Calcineurin; Calcium; | 1994 |
Effects of remoxipride and raclopride on prolactin release from clonal pituitary tumour cells.
Topics: Animals; Calcium Channel Blockers; Clone Cells; Dopamine Agonists; Dopamine Antagonists; Ergolines; | 1995 |
Membrane depolarization inhibits Kv1.5 voltage-gated K+ channel gene transcription and protein expression in pituitary cells.
Topics: Amiloride; Animals; Calcium; Clone Cells; Down-Regulation; Gene Expression; Kv1.5 Potassium Channel; | 1995 |
cis-FFA do not alter membrane depolarization but block Ca2+ influx and GH secretion in KCl-stimulated somatotroph cells. Suggestion for a direct cis-FFA perturbation of the Ca2+ channel opening.
Topics: Animals; Calcium; Calcium Channels; Cells, Cultured; Ethanol; Fatty Acids, Nonesterified; Fatty Acid | 1997 |
Characterization of the calcium response to thyrotropin-releasing hormone (TRH) in cells transfected with TRH receptor complementary DNA: importance of voltage-sensitive calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
Measurement of intracellular cadmium with fluorescent dyes. Further evidence for the role of calcium channels in cadmium uptake.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
Maitotoxin induces a calcium-dependent membrane depolarization in GH4C1 pituitary cells via activation of type L voltage-dependent calcium channels.
Topics: Animals; Calcium; Calcium Channels; Cell Membrane; Choline; Dose-Response Relationship, Drug; Isradi | 1992 |
Thapsigargin, but not caffeine, blocks the ability of thyrotropin-releasing hormone to release Ca2+ from an intracellular store in GH4C1 pituitary cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Multiple classes of calcium channels in mouse pituitary tumor cells.
Topics: Adrenocorticotropic Hormone; Animals; Calcium; Cell Membrane; Clone Cells; Cobalt; Corticotropin-Rel | 1986 |
Dihydropyridine modulators of voltage-sensitive Ca2+ channels specifically regulate prolactin production by GH4C1 pituitary tumor cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1987 |
Dihydropyridine Ca2+ antagonists: potent inhibitors of secretion from normal and transformed pituitary cells.
Topics: Animals; Calcium Channel Blockers; Cell Line; Growth Hormone; Nicotinic Acids; Nifedipine; Nimodipin | 1985 |