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nimodipine and Calcinosis

nimodipine has been researched along with Calcinosis in 2 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Calcinosis: Pathologic deposition of calcium salts in tissues.

Research Excerpts

ExcerptRelevanceReference
" To investigate whether similar effects are present in the hippocampus, AMPA dose-response and calcium movement blockade were performed."1.35Nimodipine inhibits TMB-8 potentiation of AMPA-induced hippocampal neurodegeneration. ( Bernal, F; Mahy, N; Petegnief, V; Pugliese, M; Rodríguez, MJ; Ursu, G, 2009)
" Because of the lack of specificity of ibotenic acid for a glutamate receptor subtype, a dose-response study with alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate was undertaken and calcified areas (identified with Alizarin Red staining) as well as astro- and microglial reactions (by autoradiography with [3H]lazabemide and [3H]Ro 5-4864) were quantified at one month post-lesion."1.30Long-term effects of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate and 6-nitro-7-sulphamoylbenzo(f)quinoxaline-2,3-dione in the rat basal ganglia: calcification, changes in glutamate receptors and glial reactions. ( Cummins, DJ; Dewar, D; Dragunow, M; Mahy, N; Petegnief, V; Saura, J, 1999)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bernal, F1
Petegnief, V2
Rodríguez, MJ1
Ursu, G1
Pugliese, M1
Mahy, N2
Saura, J1
Dewar, D1
Cummins, DJ1
Dragunow, M1

Other Studies

2 other studies available for nimodipine and Calcinosis

ArticleYear
Nimodipine inhibits TMB-8 potentiation of AMPA-induced hippocampal neurodegeneration.
    Journal of neuroscience research, 2009, Volume: 87, Issue:5

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Anthraquino

2009
Long-term effects of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate and 6-nitro-7-sulphamoylbenzo(f)quinoxaline-2,3-dione in the rat basal ganglia: calcification, changes in glutamate receptors and glial reactions.
    Neuroscience, 1999, Volume: 94, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Autoradiography; Basa

1999