Page last updated: 2024-11-01

nimodipine and Brain Hemorrhage, Cerebral

nimodipine has been researched along with Brain Hemorrhage, Cerebral in 25 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Research Excerpts

ExcerptRelevanceReference
"One of the main limitations of intracerebral hemorrhage (ICH) research is lack of reproducible animal models."5.33Nimodipine treatment to assess a modified mouse model of intracerebral hemorrhage. ( Ma, B; Zhang, J, 2006)
"In experiments on awake cats before and after intracerebral hemorrhage influence of cerebrocrast and nimodipine intravenous infusion (1 microgram/kg-1/min-1 during 60 min) on cerebral blood flow (CBF) in the cortex, thalamus and reticular formation and power of (alpha + beta)-, theta-, and delta-waves was investigated."3.68[Effects of cerebrocrast on local cerebral circulation and EEG in cats with cerebral hemorrhage]. ( Bisenieks, EA; Chernysheva, GA; Dubur, GIa; Makarova, NV; Plotnikov, MB; Uldrikis, IaR, 1992)
"In acute intracerebral hemorrhage the beneficial effect of recombinant coagulation factor VII found in a small study could not be proved in a large phase III trial."2.45[Pharmacotherapy of stroke]. ( Bereczki, D, 2009)
"Nimodipine treatment given before experimental ischemic insult, resulting from either vascular occlusion or intracranial hemorrhage or after subarachnoid hemorrhage, maintained or improved blood flow and minimized the severity of subsequent brain damage."2.38Efficacy of nimodipine in cerebral ischemia or hemorrhage. ( Graham, DI; Harper, AM; McCulloch, J; Mendelow, AD; Teasdale, G, 1990)
"Bath-related thunderclap headache (BRTH) is a rare and usually benign condition."1.39Bath-related thunderclap headache associated with subarachnoid and intracerebral hemorrhage. ( Chen, YY; Jhang, KM; Lee, KW; Lin, CH, 2013)
"One of the main limitations of intracerebral hemorrhage (ICH) research is lack of reproducible animal models."1.33Nimodipine treatment to assess a modified mouse model of intracerebral hemorrhage. ( Ma, B; Zhang, J, 2006)
"Nimodipine infusion was started before surgery."1.29Causes of morbidity and mortality after ruptured aneurysm surgery in a series of 230 patients. The importance of control angiography. ( Creissard, P; Freger, P; Hannequin, D; Langlois, O; Proust, F, 1995)
"Among the 141 patients with subarachnoid hemorrhage but not intracerebral or intraventricular hematoma, 16 made an unfavorable outcome, ie, 11% versus 56% among patients with intracerebral hematoma/intraventricular hematoma on preoperative computed tomography scan."1.28Unfavorable outcome following early surgical repair of ruptured cerebral aneurysms--a critical review of 238 patients. ( Auer, LM, 1991)
"The postoperative intracerebral hemorrhage occurred in 16 cases and seemed to be caused by one or more of the following events: cerebral infarction developed during the preoperative period, occlusion of the cerebral veins during the Sylvian dissection, cerebral retraction and/or sudden change of intracranial hemodynamics."1.28Surgery of intracranial aneurysms at Yonsei University: 780 cases. ( Lee, KC, 1991)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19905 (20.00)18.7374
1990's11 (44.00)18.2507
2000's3 (12.00)29.6817
2010's3 (12.00)24.3611
2020's3 (12.00)2.80

Authors

AuthorsStudies
Hawkes, MA1
Hlavnicka, AA1
Wainsztein, NA1
Allen, A1
Raz, E1
Huang, P1
Rostanski, SK1
Son, M1
Kim, DD1
Kiwan, R1
Mayich, M1
Khaw, AV1
Beez, T1
Steiger, HJ1
Etminan, N1
Jhang, KM1
Lin, CH1
Lee, KW1
Chen, YY1
Bereczki, D1
Raja, W1
Yousef, A1
Ahmed, MI1
Waheed, S1
Ma, B1
Zhang, J1
Jiang, WJ1
Du, B1
Leung, TW1
Xu, XT1
Jin, M1
Dong, KH1
Proust, F1
Hannequin, D1
Langlois, O1
Freger, P2
Creissard, P2
Mathiesen, T1
Kakarieka, A1
Edner, G1
Fahy, BG1
Watanabe, H1
Clozel, M1
Clozel, JP1
Morgan, MK1
Sekhon, LH1
Finfer, S1
Grinnell, V1
Chernysheva, GA1
Plotnikov, MB1
Bisenieks, EA1
Makarova, NV1
Uldrikis, IaR1
Dubur, GIa1
Hennerici, MG1
Auer, LM1
Lee, KC1
Teasdale, G1
Mendelow, AD2
Graham, DI2
Harper, AM1
McCulloch, J1
Rabehenoina, C1
Sevrain, L1
Hattab, N1
Tadie, M1
Clavier, E1
Thiebot, J1
Laissy, JP1
Gilsbach, JM1
Harders, AG1
Sinar, EJ1
Teasdale, GM1
Oliver Abadal, B1
Sagués Gabarró, F1
Bartumeus Jené, F1
Stullken, EH1
Johnston, WE1
Prough, DS1
Balestrieri, FJ1
McWhorter, JM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
MRI Evaluation of Nidus Occlusion After Gamma Knife Radiosurgery of Cerebral Arteriovenous Malformations - A Prospective Preliminary Study[NCT03995823]50 participants (Anticipated)Observational2019-07-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for nimodipine and Brain Hemorrhage, Cerebral

ArticleYear
Pharmacological targeting of secondary brain damage following ischemic or hemorrhagic stroke, traumatic brain injury, and bacterial meningitis - a systematic review and meta-analysis.
    BMC neurology, 2017, Dec-07, Volume: 17, Issue:1

    Topics: Brain Damage, Chronic; Brain Injuries, Traumatic; Brain Ischemia; Cerebral Hemorrhage; Dexamethasone

2017
[Pharmacotherapy of stroke].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2009, Volume: 11, Issue:1

    Topics: Acute Disease; Aspirin; Brain Ischemia; Cerebral Hemorrhage; Fibrinolytic Agents; Humans; Hungary; N

2009
New aspects of calcium antagonists for treatment of cerebrovascular disease.
    Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 10

    Topics: Brain Ischemia; Calcium Channel Blockers; Cerebral Hemorrhage; Humans; Nimodipine

1991
Efficacy of nimodipine in cerebral ischemia or hemorrhage.
    Stroke, 1990, Volume: 21, Issue:12 Suppl

    Topics: Animals; Cerebral Hemorrhage; Disease Models, Animal; Humans; Ischemic Attack, Transient; Nimodipine

1990
[Prevention of cerebral vasospasm caused by the rupture of intracranial aneurysms].
    Revista clinica espanola, 1988, Volume: 182, Issue:3

    Topics: Cerebral Hemorrhage; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Nimodipine; Rupture,

1988

Trials

1 trial available for nimodipine and Brain Hemorrhage, Cerebral

ArticleYear
Implications of nimodipine prophylaxis of cerebral vasospasm on anesthetic management during intracranial aneurysm clipping.
    Journal of neurosurgery, 1985, Volume: 62, Issue:2

    Topics: Anesthesia; Calcium Channel Blockers; Cerebral Hemorrhage; Cerebrovascular Circulation; Clinical Tri

1985

Other Studies

19 other studies available for nimodipine and Brain Hemorrhage, Cerebral

ArticleYear
Reversible Cerebral Vasoconstriction Syndrome Responsive to Intravenous Milrinone.
    Neurocritical care, 2020, Volume: 32, Issue:1

    Topics: Adult; Angiography, Digital Subtraction; Aphasia, Broca; Brain Edema; Cerebral Hemorrhage; Computed

2020
Large Subcortical Intracerebral Hemorrhage Because of Reversible Cerebral Vasoconstriction Syndrome: A Case Study.
    Stroke, 2020, Volume: 51, Issue:11

    Topics: Adult; Aneurysm, False; Cerebral Angiography; Cerebral Hemorrhage; Computed Tomography Angiography;

2020
Pearls & Oy-sters: A Journey Through Reversible Cerebral Vasoconstriction Syndrome: Sex, Drugs, and Headaches.
    Neurology, 2021, 03-30, Volume: 96, Issue:13

    Topics: Adult; Angiography, Digital Subtraction; Cerebral Hemorrhage; Cerebrovascular Disorders; Coitus; Con

2021
Bath-related thunderclap headache associated with subarachnoid and intracerebral hemorrhage.
    Acta neurologica Taiwanica, 2013, Volume: 22, Issue:3

    Topics: Baths; Cerebral Hemorrhage; Female; Headache Disorders, Primary; Humans; Magnetic Resonance Angiogra

2013
Neurofibromatosis-1 with intraventricular haemorrhage and pectus excavatum.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2012, Volume: 22, Issue:10

    Topics: Adolescent; Arteriovenous Malformations; Cerebral Hemorrhage; Diagnosis, Differential; Funnel Chest;

2012
Nimodipine treatment to assess a modified mouse model of intracerebral hemorrhage.
    Brain research, 2006, Mar-17, Volume: 1078, Issue:1

    Topics: Analysis of Variance; Animals; Brain Chemistry; Calcium Channel Blockers; Cerebral Hemorrhage; Cereb

2006
Symptomatic intracranial stenosis: cerebrovascular complications from elective stent placement.
    Radiology, 2007, Volume: 243, Issue:1

    Topics: Adolescent; Adult; Aged; Angioplasty, Balloon; Cerebral Hemorrhage; Female; Humans; Intracranial Art

2007
[Prevention of spasms after subarachnoidal hemorrhage].
    MMW, Munchener medizinische Wochenschrift, 1983, Dec-09, Volume: 125, Issue:49

    Topics: Cerebral Hemorrhage; Cerebrovascular Circulation; Humans; Nicotinic Acids; Nimodipine; Spasm

1983
Causes of morbidity and mortality after ruptured aneurysm surgery in a series of 230 patients. The importance of control angiography.
    Stroke, 1995, Volume: 26, Issue:9

    Topics: Adolescent; Adult; Aged; Aneurysm, Ruptured; Brain Ischemia; Cerebral Angiography; Cerebral Hemorrha

1995
Traumatic intracerebral lesions without extracerebral haematoma in 218 patients.
    Acta neurochirurgica, 1995, Volume: 137, Issue:3-4

    Topics: Adult; Brain Concussion; Brain Damage, Chronic; Calcium Channel Blockers; Cerebral Hemorrhage; Combi

1995
Pseudoobstruction of the colon: early recognition and therapy.
    Journal of neurosurgical anesthesiology, 1996, Volume: 8, Issue:2

    Topics: Aged; Calcium Channel Blockers; Cerebral Hemorrhage; Colonic Pseudo-Obstruction; Colonoscopy; Female

1996
Nimodipine does not increase cerebral blood flow during subarachnoid hemorrhage in the rat.
    Pharmacology, 1996, Volume: 53, Issue:1

    Topics: Animals; Blood Transfusion, Autologous; Cerebral Hemorrhage; Cerebrovascular Circulation; Cisterna M

1996
Delayed neurological deterioration following resection of arteriovenous malformations of the brain.
    Journal of neurosurgery, 1999, Volume: 90, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Aneurysm; Anticoagulants; Antihypertensive Agents; Asp

1999
[Effects of cerebrocrast on local cerebral circulation and EEG in cats with cerebral hemorrhage].
    Biulleten' eksperimental'noi biologii i meditsiny, 1992, Volume: 114, Issue:7

    Topics: Animals; Brain; Calcium Channel Blockers; Cats; Cerebral Hemorrhage; Cerebrovascular Circulation; El

1992
Unfavorable outcome following early surgical repair of ruptured cerebral aneurysms--a critical review of 238 patients.
    Surgical neurology, 1991, Volume: 35, Issue:2

    Topics: Aged; Cerebral Hemorrhage; Female; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Male;

1991
Surgery of intracranial aneurysms at Yonsei University: 780 cases.
    The Keio journal of medicine, 1991, Volume: 40, Issue:1

    Topics: Brain Ischemia; Cerebral Hemorrhage; Humans; Hydrocephalus; Intracranial Aneurysm; Nimodipine; Posto

1991
[The value of a computer tomography scanner and controlled arteriography in the study of the results of aneurysm surgery. A series of 100 consecutive cases].
    Neuro-Chirurgie, 1990, Volume: 36, Issue:4

    Topics: Adult; Aged; Aneurysm; Angiography; Carotid Artery Diseases; Cerebral Angiography; Cerebral Hemorrha

1990
Morbidity and mortality after early aneurysm surgery--a prospective study with nimodipine prevention.
    Acta neurochirurgica, 1989, Volume: 96, Issue:1-2

    Topics: Adult; Aged; Brain Ischemia; Cerebral Arteries; Cerebral Hemorrhage; Cerebral Infarction; Combined M

1989
Experimental intracerebral haemorrhage: the effect of nimodipine pretreatment.
    Journal of neurology, neurosurgery, and psychiatry, 1988, Volume: 51, Issue:5

    Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Cerebral Hemorrhage; Cerebrovascular Ci

1988