nimodipine has been researched along with Brain Disorders in 13 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present work studied the effect of a calcium channel blocker (nimodipine) on rat behavioural changes and brain lesions observed after seizures induced by high doses of pilocarpine (400 mg/kg, s." | 7.69 | Inhibitory action of a calcium channel blocker (nimodipine) on seizures and brain damage induced by pilocarpine and lithium-pilocarpine in rats. ( Aguiar, LM; de Bruin, VM; de Pinho, RS; de Sousa, FC; Marinho, MM; Viana, GS, 1997) |
| "Nimodipine-treated rats received the drug as an intravenous infusion of 0." | 5.28 | Nimodipine prevents hyperglycemia-induced cerebral acidosis in middle cerebral artery occluded rats. ( Berger, L; Hakim, AM, 1989) |
| "The present work studied the effect of a calcium channel blocker (nimodipine) on rat behavioural changes and brain lesions observed after seizures induced by high doses of pilocarpine (400 mg/kg, s." | 3.69 | Inhibitory action of a calcium channel blocker (nimodipine) on seizures and brain damage induced by pilocarpine and lithium-pilocarpine in rats. ( Aguiar, LM; de Bruin, VM; de Pinho, RS; de Sousa, FC; Marinho, MM; Viana, GS, 1997) |
| "Nimodipine-treated rats received the drug as an intravenous infusion of 0." | 1.28 | Nimodipine prevents hyperglycemia-induced cerebral acidosis in middle cerebral artery occluded rats. ( Berger, L; Hakim, AM, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 1 |
| Chen, Y | 1 |
| Liu, J | 1 |
| Mai, X | 1 |
| Jing, S | 1 |
| McIlroy, E | 1 |
| Sethuraman, R | 1 |
| Woograsingh, R | 1 |
| Nelson-Piercy, C | 1 |
| Gilbert-Kawai, E | 1 |
| Kleffner, I | 1 |
| Ringelstein, EB | 1 |
| Stupp, N | 1 |
| Niederstadt, TU | 1 |
| Young, P | 1 |
| Woolridge, D | 1 |
| Stefanelli, M | 1 |
| Hoppe, B | 1 |
| Trembly, B | 1 |
| Berg, M | 1 |
| Bruhn, T | 1 |
| Frandsen, A | 1 |
| Schousboe, A | 1 |
| Diemer, NH | 1 |
| Nelson, C | 1 |
| Finger, S | 1 |
| Simons, D | 1 |
| Marinho, MM | 1 |
| de Bruin, VM | 1 |
| de Sousa, FC | 1 |
| Aguiar, LM | 1 |
| de Pinho, RS | 1 |
| Viana, GS | 1 |
| Morgan, MK | 1 |
| Sekhon, LH | 1 |
| Finfer, S | 1 |
| Grinnell, V | 1 |
| Pontecorvo, MJ | 1 |
| Karbon, EW | 1 |
| Goode, S | 1 |
| Clissold, DB | 1 |
| Borosky, SA | 1 |
| Patch, RJ | 1 |
| Ferkany, JW | 1 |
| Aldenhoff, J | 1 |
| Berger, L | 1 |
| Hakim, AM | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| MRI Evaluation of Nidus Occlusion After Gamma Knife Radiosurgery of Cerebral Arteriovenous Malformations - A Prospective Preliminary Study[NCT03995823] | 50 participants (Anticipated) | Observational | 2019-07-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nimodipine and Brain Disorders
| Article | Year |
|---|---|
Clinical potential for the use of neuroprotective agents. A brief overview.
Topics: Animals; Brain Diseases; Brain Injuries; Brain Ischemia; Calcium Channel Blockers; Cerebrovascular D | 1995 |
12 other studies available for nimodipine and Brain Disorders
| Article | Year |
|---|---|
Is it coincidental or correlative between reversible splenial lesion syndrome and atrial septal defect?: A case report.
Topics: Administration, Oral; Antihypertensive Agents; Aspirin; Brain Diseases; Corpus Callosum; Diffusion M | 2020 |
Severe Postpartum Headache and Hypertension Caused by Reversible Cerebral Vasoconstriction Syndrome: A Case Report.
Topics: Adult; Anesthesia, Epidural; Brain Diseases; Female; Headache; Humans; Hypertension; Magnetic Resona | 2017 |
Neurological picture. Susac's syndrome: effective combination of immunosuppression and antiplatelet treatment.
Topics: Adolescent; Aspirin; Brain Diseases; Corpus Callosum; Female; Glucocorticoids; Hearing Loss; Humans; | 2006 |
Susac syndrome with frontal intermittent rhythmic delta activity (FIRDA).
Topics: Adult; Brain Diseases; Calcium Channel Blockers; Delta Rhythm; Gait Disorders, Neurologic; Hearing L | 2006 |
Kainic acid-induced seizures and brain damage in the rat: role of calcium homeostasis.
Topics: Animals; Behavior, Animal; Body Temperature; Brain Diseases; Calcium; Calcium Channels; Dantrolene; | 1995 |
Effects of nimodipine on two neurologic measures sensitive to sensorimotor cortex damage.
Topics: Analysis of Variance; Animals; Brain Diseases; Female; Motor Activity; Motor Cortex; Neuropsychologi | 1993 |
Inhibitory action of a calcium channel blocker (nimodipine) on seizures and brain damage induced by pilocarpine and lithium-pilocarpine in rats.
Topics: Animals; Atropine; Brain Diseases; Lithium; Male; Nimodipine; Pilocarpine; Rats; Rats, Wistar; Seizu | 1997 |
Delayed neurological deterioration following resection of arteriovenous malformations of the brain.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Aneurysm; Anticoagulants; Antihypertensive Agents; Asp | 1999 |
Possible cerebroprotective and in vivo NMDA antagonist activities of sigma agents.
Topics: Animals; Anticonvulsants; Brain Diseases; Electroshock; Haloperidol; Hypoxia; Male; Mice; Mice, Inbr | 1991 |
[Calcium antagonists for the aging brain].
Topics: Aging; Animals; Brain Diseases; Calcium Channel Blockers; Nimodipine; Rats | 1991 |
Nimodipine prevents hyperglycemia-induced cerebral acidosis in middle cerebral artery occluded rats.
Topics: Acidosis; Animals; Brain Diseases; Brain Ischemia; Cerebrovascular Circulation; Hydrogen-Ion Concent | 1989 |
Cerebral acidosis in focal ischemia: II. Nimodipine and verapamil normalize cerebral pH following middle cerebral artery occlusion in the rat.
Topics: Acidosis; Animals; Arterial Occlusive Diseases; Brain; Brain Diseases; Brain Ischemia; Calcium Chann | 1986 |