nimodipine has been researched along with Brain Diseases in 13 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present work studied the effect of a calcium channel blocker (nimodipine) on rat behavioural changes and brain lesions observed after seizures induced by high doses of pilocarpine (400 mg/kg, s." | 7.69 | Inhibitory action of a calcium channel blocker (nimodipine) on seizures and brain damage induced by pilocarpine and lithium-pilocarpine in rats. ( Aguiar, LM; de Bruin, VM; de Pinho, RS; de Sousa, FC; Marinho, MM; Viana, GS, 1997) |
| "Nimodipine-treated rats received the drug as an intravenous infusion of 0." | 5.28 | Nimodipine prevents hyperglycemia-induced cerebral acidosis in middle cerebral artery occluded rats. ( Berger, L; Hakim, AM, 1989) |
| "The present work studied the effect of a calcium channel blocker (nimodipine) on rat behavioural changes and brain lesions observed after seizures induced by high doses of pilocarpine (400 mg/kg, s." | 3.69 | Inhibitory action of a calcium channel blocker (nimodipine) on seizures and brain damage induced by pilocarpine and lithium-pilocarpine in rats. ( Aguiar, LM; de Bruin, VM; de Pinho, RS; de Sousa, FC; Marinho, MM; Viana, GS, 1997) |
| "Nimodipine-treated rats received the drug as an intravenous infusion of 0." | 1.28 | Nimodipine prevents hyperglycemia-induced cerebral acidosis in middle cerebral artery occluded rats. ( Berger, L; Hakim, AM, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 1 |
| Chen, Y | 1 |
| Liu, J | 1 |
| Mai, X | 1 |
| Jing, S | 1 |
| McIlroy, E | 1 |
| Sethuraman, R | 1 |
| Woograsingh, R | 1 |
| Nelson-Piercy, C | 1 |
| Gilbert-Kawai, E | 1 |
| Kleffner, I | 1 |
| Ringelstein, EB | 1 |
| Stupp, N | 1 |
| Niederstadt, TU | 1 |
| Young, P | 1 |
| Woolridge, D | 1 |
| Stefanelli, M | 1 |
| Hoppe, B | 1 |
| Trembly, B | 1 |
| Berg, M | 1 |
| Bruhn, T | 1 |
| Frandsen, A | 1 |
| Schousboe, A | 1 |
| Diemer, NH | 1 |
| Nelson, C | 1 |
| Finger, S | 1 |
| Simons, D | 1 |
| Marinho, MM | 1 |
| de Bruin, VM | 1 |
| de Sousa, FC | 1 |
| Aguiar, LM | 1 |
| de Pinho, RS | 1 |
| Viana, GS | 1 |
| Morgan, MK | 1 |
| Sekhon, LH | 1 |
| Finfer, S | 1 |
| Grinnell, V | 1 |
| Pontecorvo, MJ | 1 |
| Karbon, EW | 1 |
| Goode, S | 1 |
| Clissold, DB | 1 |
| Borosky, SA | 1 |
| Patch, RJ | 1 |
| Ferkany, JW | 1 |
| Aldenhoff, J | 1 |
| Berger, L | 1 |
| Hakim, AM | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| MRI Evaluation of Nidus Occlusion After Gamma Knife Radiosurgery of Cerebral Arteriovenous Malformations - A Prospective Preliminary Study[NCT03995823] | 50 participants (Anticipated) | Observational | 2019-07-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nimodipine and Brain Diseases
| Article | Year |
|---|---|
Clinical potential for the use of neuroprotective agents. A brief overview.
Topics: Animals; Brain Diseases; Brain Injuries; Brain Ischemia; Calcium Channel Blockers; Cerebrovascular D | 1995 |
12 other studies available for nimodipine and Brain Diseases
| Article | Year |
|---|---|
Is it coincidental or correlative between reversible splenial lesion syndrome and atrial septal defect?: A case report.
Topics: Administration, Oral; Antihypertensive Agents; Aspirin; Brain Diseases; Corpus Callosum; Diffusion M | 2020 |
Severe Postpartum Headache and Hypertension Caused by Reversible Cerebral Vasoconstriction Syndrome: A Case Report.
Topics: Adult; Anesthesia, Epidural; Brain Diseases; Female; Headache; Humans; Hypertension; Magnetic Resona | 2017 |
Neurological picture. Susac's syndrome: effective combination of immunosuppression and antiplatelet treatment.
Topics: Adolescent; Aspirin; Brain Diseases; Corpus Callosum; Female; Glucocorticoids; Hearing Loss; Humans; | 2006 |
Susac syndrome with frontal intermittent rhythmic delta activity (FIRDA).
Topics: Adult; Brain Diseases; Calcium Channel Blockers; Delta Rhythm; Gait Disorders, Neurologic; Hearing L | 2006 |
Kainic acid-induced seizures and brain damage in the rat: role of calcium homeostasis.
Topics: Animals; Behavior, Animal; Body Temperature; Brain Diseases; Calcium; Calcium Channels; Dantrolene; | 1995 |
Effects of nimodipine on two neurologic measures sensitive to sensorimotor cortex damage.
Topics: Analysis of Variance; Animals; Brain Diseases; Female; Motor Activity; Motor Cortex; Neuropsychologi | 1993 |
Inhibitory action of a calcium channel blocker (nimodipine) on seizures and brain damage induced by pilocarpine and lithium-pilocarpine in rats.
Topics: Animals; Atropine; Brain Diseases; Lithium; Male; Nimodipine; Pilocarpine; Rats; Rats, Wistar; Seizu | 1997 |
Delayed neurological deterioration following resection of arteriovenous malformations of the brain.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Aneurysm; Anticoagulants; Antihypertensive Agents; Asp | 1999 |
Possible cerebroprotective and in vivo NMDA antagonist activities of sigma agents.
Topics: Animals; Anticonvulsants; Brain Diseases; Electroshock; Haloperidol; Hypoxia; Male; Mice; Mice, Inbr | 1991 |
[Calcium antagonists for the aging brain].
Topics: Aging; Animals; Brain Diseases; Calcium Channel Blockers; Nimodipine; Rats | 1991 |
Nimodipine prevents hyperglycemia-induced cerebral acidosis in middle cerebral artery occluded rats.
Topics: Acidosis; Animals; Brain Diseases; Brain Ischemia; Cerebrovascular Circulation; Hydrogen-Ion Concent | 1989 |
Cerebral acidosis in focal ischemia: II. Nimodipine and verapamil normalize cerebral pH following middle cerebral artery occlusion in the rat.
Topics: Acidosis; Animals; Arterial Occlusive Diseases; Brain; Brain Diseases; Brain Ischemia; Calcium Chann | 1986 |