nimodipine has been researched along with Body Weight in 21 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Animals in the treated group received nimodipine (15 mg/kg of body weight), and those of the control group received a placebo." | 7.68 | Effect of nimodipine on subintimal hyperplasia of autologous vein bypass grafts in rats: a placebo-controlled study. ( Chignier, E; Guyotat, J; Lievre, M; Pelissou-Guyotat, I, 1991) |
| "The effect of the calcium channel blocker nimodipine on the previously described regional cerebral acidosis accompanying thiamine deficiency was investigated." | 7.67 | Effect of nimodipine on the regional cerebral acidosis accompanying thiamine deficiency in the rat. ( Hakim, AM; Vogel, S, 1988) |
| "Sustained high levels of corticosterone (CORT), one of the major stress-induced hormones in the rat, were suggested as generating 'accelerated brain aging' and were shown to induce both specific brain changes in the hippocampus and learning impairments in young and middle-aged Fischer-344 rats." | 3.69 | Nimodipine's protection against corticosterone-induced morphological changes in the hippocampus of young rats. ( Dachir, S; Kadar, T; Levy, A; Robinzon, B, 1997) |
| " Animals in the treated group received nimodipine (15 mg/kg of body weight), and those of the control group received a placebo." | 3.68 | Effect of nimodipine on subintimal hyperplasia of autologous vein bypass grafts in rats: a placebo-controlled study. ( Chignier, E; Guyotat, J; Lievre, M; Pelissou-Guyotat, I, 1991) |
| "The effect of the calcium channel blocker nimodipine on the previously described regional cerebral acidosis accompanying thiamine deficiency was investigated." | 3.67 | Effect of nimodipine on the regional cerebral acidosis accompanying thiamine deficiency in the rat. ( Hakim, AM; Vogel, S, 1988) |
| "Female mice received whole brain irradiation (WBI) and were treated with saline, nimodipine, hUC-MSCs, or hUC-MSCs combined with nimodipine." | 1.43 | Neuroprotective effects of human umbilical cord-derived mesenchymal stromal cells combined with nimodipine against radiation-induced brain injury through inhibition of apoptosis. ( Duan, HF; Li, T; Liu, J; Liu, Y; Lu, Y; Qin, YR; Wang, GH; Wu, XB, 2016) |
| "Both nimodipine treatments prevented the memory deficits when these were measured between 1 and 2 months after alcohol withdrawal." | 1.35 | Nimodipine prior to alcohol withdrawal prevents memory deficits during the abstinence phase. ( Brooks, SP; Croft, AP; Little, HJ; Norman, G; Shaw, SG, 2008) |
| "Nimodipine treatment partially prevented deficits in nerve conduction velocity and hippocampal long-term potentiation in diabetic rats." | 1.33 | Effects of the Ca2+ antagonist nimodipine on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats. ( Biessels, GJ; Gispen, WH; Kamal, A; ter Laak, MP, 2005) |
| "[3H]Nimodipine was administered 5 min after laminectomy in the control group, and at the above-specified times after injury in the SCI groups." | 1.30 | Autoradiographic [3H]nimodipine distribution after experimental spinal cord injury in rats. ( Koyanagi, I; Ross, IB; Tator, CH; Wallace, MC, 1999) |
| "Treatment with nimodipine (20 mg kg-1) from week 6 onwards significantly increased the sciatic nerve blood flow as compared to placebo-treated diabetic BB/Wor rats." | 1.29 | Beneficial effect of the Ca2+ antagonist, nimodipine, on existing diabetic neuropathy in the BB/Wor rat. ( Biessels, G; Bravenboer, B; de Wildt, DJ; Gispen, WH; Kappelle, AC; Traber, J; van Buren, T, 1994) |
| "Treatment with nimodipine restored the reduced presynaptic responsiveness independent of the postsynaptic adrenergic hyporesponsiveness." | 1.29 | Effects of nimodipine on sciatic nerve blood flow and vasa nervorum responsiveness in the diabetic rat. ( Biessels, GJ; De Wildt, DJ; Erkelens, DW; Gispen, WH; Kappelle, AC; Van Buren, T, 1993) |
| "This nimodipine effect was not observed in rats with partial lesions of the medial septal region." | 1.29 | Nimodipine's functional benefits depend on lesion completeness in medial septal area. ( Isaacson, RL; Poplawsky, A, 1993) |
| " Intraperitoneal treatment with the Ca2+ channel blocker, nimodipine, from week 4 onwards, in a dosage of 10 mg kg-1 or 20 mg kg-1 intraperitoneally per 48 h, resulted in a significant increase in sensory and motor nerve conduction velocity whereas treatment with 5 mg kg-1 intraperitoneally per 48 h was not effective." | 1.29 | Amelioration by the Ca2+ antagonist, nimodipine of an existing neuropathy in the streptozotocin-induced, diabetic rat. ( Bravenboer, B; Erkelens, DW; Gispen, WH; Kappelle, AC; Traber, J; van Buren, T, 1993) |
| " Three minutes after pretreatment, group 1 (n = 11), group 3 (n = 10), and their respective control groups (n = 11 and n = 9) received intravenous bupivacaine LD50 (median lethal dose)." | 1.28 | Nimodipine reduces the toxicity of intravenous bupivacaine in rats. ( Horn, JL; Hyman, SA; Kambam, JR; Kinney, WW; Skelley, CC, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 13 (61.90) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 3 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, J | 1 |
| Cao, H | 1 |
| Zhang, Y | 2 |
| Ma, J | 1 |
| Wang, J | 1 |
| Gao, Y | 1 |
| Zhang, X | 1 |
| Zhang, F | 1 |
| Chu, L | 1 |
| Wang, GH | 1 |
| Liu, Y | 1 |
| Wu, XB | 1 |
| Lu, Y | 1 |
| Liu, J | 1 |
| Qin, YR | 1 |
| Li, T | 1 |
| Duan, HF | 1 |
| Brooks, SP | 1 |
| Croft, AP | 1 |
| Norman, G | 1 |
| Shaw, SG | 1 |
| Little, HJ | 1 |
| Marçal, DM | 1 |
| Rizzi, E | 1 |
| Martins-Oliveira, A | 1 |
| Ceron, CS | 1 |
| Guimaraes, DA | 1 |
| Gerlach, RF | 1 |
| Tanus-Santos, JE | 1 |
| Biessels, GJ | 2 |
| ter Laak, MP | 1 |
| Kamal, A | 1 |
| Gispen, WH | 4 |
| Kappelle, AC | 3 |
| Biessels, G | 1 |
| Bravenboer, B | 2 |
| van Buren, T | 3 |
| Traber, J | 2 |
| de Wildt, DJ | 2 |
| Erkelens, DW | 2 |
| Ueda, M | 1 |
| Masui, M | 1 |
| Kawakami, M | 1 |
| Matsunaga, K | 1 |
| Gemba, T | 1 |
| Ninomiya, M | 1 |
| Nakano, A | 1 |
| Torii, M | 1 |
| Adachi, I | 1 |
| Ito, H | 1 |
| Isaacson, RL | 1 |
| Poplawsky, A | 1 |
| Zhang, LY | 1 |
| Feng, YP | 1 |
| Okopién, B | 1 |
| Trzeciak, HI | 1 |
| Ristic, H | 1 |
| Wiley, JW | 1 |
| Hall, KE | 1 |
| Sima, AA | 1 |
| Dachir, S | 1 |
| Kadar, T | 1 |
| Robinzon, B | 1 |
| Levy, A | 1 |
| Meneses, A | 1 |
| Terrón, JA | 1 |
| Ibarra, M | 1 |
| Hong, E | 1 |
| Ross, IB | 1 |
| Koyanagi, I | 1 |
| Wallace, MC | 1 |
| Tator, CH | 1 |
| Katagiri, H | 1 |
| Kagaya, A | 1 |
| Nakae, S | 1 |
| Morinobu, S | 1 |
| Yamawaki, S | 1 |
| Hyman, SA | 1 |
| Kinney, WW | 1 |
| Horn, JL | 1 |
| Skelley, CC | 1 |
| Kambam, JR | 1 |
| Pelissou-Guyotat, I | 1 |
| Guyotat, J | 1 |
| Lievre, M | 1 |
| Chignier, E | 1 |
| Angrisani, M | 1 |
| Loffreda, A | 1 |
| De Santis, D | 1 |
| Filippelli, A | 1 |
| De Paola, C | 1 |
| Maione, S | 1 |
| Berrino, L | 1 |
| Matera, C | 1 |
| De Pasquale, M | 1 |
| Mauro, C | 1 |
| Vogel, S | 1 |
| Hakim, AM | 1 |
21 other studies available for nimodipine and Body Weight
| Article | Year |
|---|---|
Nephroprotective effect of calcium channel blockers against toxicity of lead exposure in mice.
Topics: Animals; Apoptosis; Blood Urea Nitrogen; Body Weight; Calcium Channel Blockers; Creatinine; Cytoprot | 2013 |
Neuroprotective effects of human umbilical cord-derived mesenchymal stromal cells combined with nimodipine against radiation-induced brain injury through inhibition of apoptosis.
Topics: Animals; Apoptosis; Astrocytes; beta-Globins; Body Weight; Brain Injuries; Cell Count; Cell Differen | 2016 |
Nimodipine prior to alcohol withdrawal prevents memory deficits during the abstinence phase.
Topics: Alcohol-Induced Disorders; Alcohols; Analysis of Variance; Animals; Body Weight; Brain; Calcium Chan | 2008 |
Comparative study on antioxidant effects and vascular matrix metalloproteinase-2 downregulation by dihydropyridines in renovascular hypertension.
Topics: Amlodipine; Animals; Antioxidants; Aorta, Thoracic; Blood Pressure; Body Weight; Calcium Channel Blo | 2011 |
Effects of the Ca2+ antagonist nimodipine on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats.
Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Brain Stem; Calcium Channel Blockers; Cen | 2005 |
Beneficial effect of the Ca2+ antagonist, nimodipine, on existing diabetic neuropathy in the BB/Wor rat.
Topics: Animals; Autonomic Nervous System; Blood Glucose; Blood Pressure; Body Weight; Diabetic Neuropathies | 1994 |
Effects of nimodipine on sciatic nerve blood flow and vasa nervorum responsiveness in the diabetic rat.
Topics: Analysis of Variance; Animals; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experi | 1993 |
Pharmacological studies on a new dihydrothienopyridine calcium antagonist. 4th communication: prophylactic and therapeutic effects of S-(+)-methyl-4,7-dihydro-3-isobutyl-6-methyl-4-(3-nitrophenyl)thieno[2, 3- b]pyridine-5-carboxylate in stroke-prone spont
Topics: Animals; Behavior, Animal; Blood Pressure; Body Weight; Brain; Calcium Channel Blockers; Cerebrovasc | 1993 |
Nimodipine's functional benefits depend on lesion completeness in medial septal area.
Topics: Animals; Behavior, Animal; Body Weight; Brain Mapping; Drinking; Eating; Emotions; Male; Motor Activ | 1993 |
Amelioration by the Ca2+ antagonist, nimodipine of an existing neuropathy in the streptozotocin-induced, diabetic rat.
Topics: Aging; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; | 1993 |
[Effect of dl-3-n-butylphthalide (NBP) on life span and neurological deficit in SHRsp rats].
Topics: Animals; Benzofurans; Blood Pressure; Body Weight; Cerebrovascular Disorders; Heart Rate; Male; Neur | 1996 |
Modification of adrenergic reactivity in rat tail artery by dietary lipids and calcium channel antagonists.
Topics: Animals; Arteries; Body Weight; Calcium Channel Blockers; Diet, Atherogenic; Dietary Fats; In Vitro | 1996 |
Failure of nimodipine to prevent or correct the long-term nerve conduction defect and increased neuronal Ca(2+)-currents in the diabetic BB/W-rat.
Topics: Animals; Blood Glucose; Body Weight; Calcium; Calcium Channel Blockers; Cohort Studies; Diabetic Neu | 1996 |
Nimodipine's protection against corticosterone-induced morphological changes in the hippocampus of young rats.
Topics: Aging; Animals; Animals, Newborn; Body Weight; Calcium Channel Blockers; Corticosterone; Hippocampus | 1997 |
Effects of nimodipine on learning in normotensive and spontaneously hypertensive rats.
Topics: Aging; Animals; Blood Pressure; Body Weight; Calcium Channel Blockers; Conditioning, Operant; Heart | 1997 |
Autoradiographic [3H]nimodipine distribution after experimental spinal cord injury in rats.
Topics: Animals; Autoradiography; Blood Gas Analysis; Blood Pressure; Body Temperature; Body Weight; Calcium | 1999 |
Modulation of serotonin2A receptor function in rats after repeated treatment with dexamethasone and L-type calcium channel antagonist nimodipine.
Topics: Animals; Anti-Inflammatory Agents; Body Weight; Calcium Channel Blockers; Calcium Channels, L-Type; | 2001 |
Nimodipine reduces the toxicity of intravenous bupivacaine in rats.
Topics: Animals; Apnea; Arrhythmias, Cardiac; Body Weight; Bupivacaine; Cardiovascular System; Drug Interact | 1992 |
Effect of nimodipine on subintimal hyperplasia of autologous vein bypass grafts in rats: a placebo-controlled study.
Topics: Animals; Body Weight; Graft Occlusion, Vascular; Hyperplasia; Kidney; Liver; Male; Nimodipine; Rats; | 1991 |
Interference of prenatal and postnatal exposure to Ca2+-antagonist agents on rat functional development of vascular system.
Topics: Acetylcholinesterase; Animals; Animals, Newborn; Blood Pressure; Body Weight; Calcium Channel Blocke | 1989 |
Effect of nimodipine on the regional cerebral acidosis accompanying thiamine deficiency in the rat.
Topics: Animals; Body Weight; Brain; Cerebrovascular Circulation; Hydrogen-Ion Concentration; Male; Nimodipi | 1988 |