Page last updated: 2024-11-01

nimodipine and Blood Pressure, High

nimodipine has been researched along with Blood Pressure, High in 55 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Research Excerpts

ExcerptRelevanceReference
"This study shows that nimodipine significantly reduces levels of blood pressure in patients with mild and moderate essential hypertension."9.06Effect of treatment with nimodipine in patients with mild and moderate essential hypertension. ( Dong, SM; Dong, XF; Lin, GZ; Liu, LS; Wang, SY; Wang, W; Xu, ZK; Yu, XH; Zhao, F, 1990)
"The current analysis shows that cerebral perfusion in the setting of secondary cerebral ischemia following SAH is measurably improved by milrinone and norepinephrine-based hyperdynamic therapy."8.12Hemodynamic response and clinical outcome following intravenous milrinone plus norepinephrine-based hyperdynamic hypertensive therapy in patients suffering secondary cerebral ischemia after aneurysmal subarachnoid hemorrhage. ( Andereggen, L; Berberat, J; Ensner, R; Marbacher, S; Remonda, L; Steiger, HJ, 2022)
"Bipolar disorder in pregnancy was treated with nimodipine, because of lithium-induced nephrogenic diabetes insipidus."7.71Calcium channel blocker, nimodipine, for the treatment of bipolar disorder during pregnancy. ( Mason, B; Utter, G; Vengalil, S; Yingling, DR, 2002)
"The efficacy and tolerability of the dihydropyridine calcium antagonist nimodipine (BAY e 9736) in the prophylaxis of ischemic neurological deficits after subarachnoid hemorrhage were investigated in 171 patients in an open, prospective, multicenter study."7.67Clinical experience with nimodipine in the prophylaxis of neurological deficits after subarachnoid hemorrhage. ( Adelt, D; Ammerer, HP; Baumann, H; Böker, DK; Grotenhuis, JA; Istaitih, AR; Jaksche, H; Karnick, R; Kazner, E; Sprung, C, 1985)
"Eighty-four patients were treated early with nimodipine intravenously, and thereafter orally, up to 21 days after aneurysmal subarachnoid hemorrhage."7.67Nimodipine treatment of selected good-risk patients with subarachnoid hemorrhage: no significant difference between present and historical results. ( Bolander, H; Carlsson, H; Pellettieri, L; Sjölander, U, 1988)
" The wafers were tested for their physical characteristics, ex vivo mucoadhesion strength, ex vivo mucoadhesion time, in vitro drug release, and in vitro permeation and in vivo bioavailability studies."5.36Development and evaluation of novel buccoadhesive wafers of nimodipine for treatment of hypertension. ( Ali, J; Ali, M; Hassan, N, 2010)
"Operative interventions in subarachnoid hemorrhages caused by brain vessel aneurysm require meticulous dissection of the latter."5.29[Controlled hypotension against a background of nimodipine during an operation on neurosurgical patients with hypertension]. ( Karadimov, D, 1995)
"Nimodipine is an effective vasodilator."5.29The haemodynamic and respiratory effects of intravenous nimodipine used in the treatment of eclampsia. ( Anthony, J; Dommisse, J; Johanson, R; Mantel, G, 1996)
" combined use of Jiangya Capsule (JYC) and Nimodipine (ND), on blood pressure, TCM clinical symptoms, and blood levels of vascular endothelial function and hypersensitive C-reactive protein (hs-CRP) in elderly patients with isolated systolic hypertension (EISH)."5.14[Effect of an integrative medical regimen on levels of vascular endothelial function and hypersensitive C-reactive protein in elderly patients with isolated systolic hypertension]. ( Han, YX; Li, H; Zhao, WM, 2009)
"200 primary hypertension patients were assigned to Xinmaitong group and Nimodipine group randomly."5.11[Clinical observation of the effect of xinmaitong tablet on hypertension]. ( Liang, B, 2005)
"An observational study based on the data from the Intravenous Nimodipine West European Stroke Trial (INWEST)."5.09High initial blood pressure after acute stroke is associated with poor functional outcome. ( Ahmed, N; Wahlgren, G, 2001)
"Possible drug interactions between the two calcium channel blockers nimodipine and nifedipine were investigated in 12 elderly patients with stable mild to moderate hypertension."5.08The influence of nimodipine on hemodynamic parameters and peak and trough plasma concentrations of nifedipine chronically administered to elderly hypertensive patients. ( Breuel, HP; Heine, PR; Kuhlmann, J; Mück, W; Niklaus, H; Schmage, N, 1995)
"This study shows that nimodipine significantly reduces levels of blood pressure in patients with mild and moderate essential hypertension."5.06Effect of treatment with nimodipine in patients with mild and moderate essential hypertension. ( Dong, SM; Dong, XF; Lin, GZ; Liu, LS; Wang, SY; Wang, W; Xu, ZK; Yu, XH; Zhao, F, 1990)
"The current analysis shows that cerebral perfusion in the setting of secondary cerebral ischemia following SAH is measurably improved by milrinone and norepinephrine-based hyperdynamic therapy."4.12Hemodynamic response and clinical outcome following intravenous milrinone plus norepinephrine-based hyperdynamic hypertensive therapy in patients suffering secondary cerebral ischemia after aneurysmal subarachnoid hemorrhage. ( Andereggen, L; Berberat, J; Ensner, R; Marbacher, S; Remonda, L; Steiger, HJ, 2022)
"Electron paramagnetic resonance (EPR) spectroscopy was used to investigate the gamma-radiation damage in the crystalline powder form of nine calcium channel blockers from the 1,4-dihydropyridine derivatives, which are in clinical use for treatment of arteria hypertension and ischemic heart disease."3.74The effect of ionizing radiation of 1,4-dihydropyridine derivatives in the solid state. ( Mielcarek, J; Naskrent, M, 2007)
"Bipolar disorder in pregnancy was treated with nimodipine, because of lithium-induced nephrogenic diabetes insipidus."3.71Calcium channel blocker, nimodipine, for the treatment of bipolar disorder during pregnancy. ( Mason, B; Utter, G; Vengalil, S; Yingling, DR, 2002)
"Eighty-four patients were treated early with nimodipine intravenously, and thereafter orally, up to 21 days after aneurysmal subarachnoid hemorrhage."3.67Nimodipine treatment of selected good-risk patients with subarachnoid hemorrhage: no significant difference between present and historical results. ( Bolander, H; Carlsson, H; Pellettieri, L; Sjölander, U, 1988)
"The efficacy and tolerability of the dihydropyridine calcium antagonist nimodipine (BAY e 9736) in the prophylaxis of ischemic neurological deficits after subarachnoid hemorrhage were investigated in 171 patients in an open, prospective, multicenter study."3.67Clinical experience with nimodipine in the prophylaxis of neurological deficits after subarachnoid hemorrhage. ( Adelt, D; Ammerer, HP; Baumann, H; Böker, DK; Grotenhuis, JA; Istaitih, AR; Jaksche, H; Karnick, R; Kazner, E; Sprung, C, 1985)
"Among these subtypes subcortical vascular dementia (SVD) may represent a well-defined entity in terms of pathophysiology, clinical features and neuroradiological aspects."2.71Therapy of vascular dementias. ( Basile, AM; Inzitari, D; Lamassa, M; Pantoni, L, 2004)
" An increasing dosage of nimodipine is accompanied by increasing cardiovascular effects."2.66[Hemodynamic effects in high-dose infusion of nimodipine, a new calcium antagonist]. ( Boldt, J; Hempelmann, G; Kling, D; Moosdorf, R; Ratthey, K; von Bormann, B, 1986)
"This process, known as cerebral vasospasm, is the most common cause of DCI after SAH."2.48Management of delayed cerebral ischemia after subarachnoid hemorrhage. ( Koenig, MA, 2012)
"She had a history of migraines and received methylergonovine at delivery."2.47A case of postpartum cerebral angiitis and review of the literature. ( Atlas, RO; Bakhru, A, 2011)
"Preeclampsia is associated with increased maternal and perinatal morbidity and mortality."2.41Management and monitoring of severe preeclampsia. ( Bolte, AC; Dekker, GA; van Geijn, HP, 2001)
" Earlier studies indicated that chronic administration of nimodipine revealed a protective effect in the occurrence of strokes in SHR-SP rats, yielding a decreased mortality rate."2.39Cerebrovascular, neuronal, and behavioral effects of long-term Ca2+ channel blockade in aging normotensive and hypertensive rat strains. ( de Jong, GI; Luiten, PG; Schuurman, T, 1994)
"For the treatment of hypertensive cerebral vasospasm, combined application of betahistine on the basis of nimodipine can effectively reduce the body's aseptic inflammatory responses, improve vascular endothelial function and increase the cerebral circulation blood flow, which offers a favorable strategy for clinical therapy."1.56Effects of nimodipine combined with betahistine on CRP and other inflammatory cytokines and vascular endothelial function in patients with hypertensive cerebral vasospasm. ( Liu, X; Luo, X; Sheng, P; Wang, Y; Xiao, P; Zeng, K; Zhao, N, 2020)
" We describe a patient with an apparent primary TCH, which repeatedly occurred immediately after micturition until she achieved a therapeutic dosage of nimodipine."1.37Thunderclap headache triggered by micturition: responsive to nimodipine. ( Gui, W; Han, YY; Liu, YM; Wang, K; Wang, Y; Zhu, J, 2011)
" The wafers were tested for their physical characteristics, ex vivo mucoadhesion strength, ex vivo mucoadhesion time, in vitro drug release, and in vitro permeation and in vivo bioavailability studies."1.36Development and evaluation of novel buccoadhesive wafers of nimodipine for treatment of hypertension. ( Ali, J; Ali, M; Hassan, N, 2010)
"Bathing headache is rarely described in literature."1.32Bathing headache: a variant of idiopathic thunderclap headache. ( Fuh, JL; Liao, YC; Lirng, JF; Lu, SR; Wang, SJ; Wu, ZA, 2003)
"Hypertension is the main cause of stroke that represents the second most common cause of death in the industrialized world and a leading cause of inability of the elderly."1.31Influence of treatment with Ca(2+) antagonists on cerebral vasculature of spontaneously hypertensive rats. ( Amenta, F; Sabbatini, M; Tomassoni, D, 2001)
"Hypertension is the main risk factor for cerebrovascular disease including vascular dementia and control of blood pressure might protect from lesions causing cognitive impairment."1.31Hypertensive brain damage: comparative evaluation of protective effect of treatment with dihydropyridine derivatives in spontaneously hypertensive rats. ( Amenta, F; Sabbatini, M; Tomassoni, D, 2001)
"Operative interventions in subarachnoid hemorrhages caused by brain vessel aneurysm require meticulous dissection of the latter."1.29[Controlled hypotension against a background of nimodipine during an operation on neurosurgical patients with hypertension]. ( Karadimov, D, 1995)
"Nimodipine is an effective vasodilator."1.29The haemodynamic and respiratory effects of intravenous nimodipine used in the treatment of eclampsia. ( Anthony, J; Dommisse, J; Johanson, R; Mantel, G, 1996)
"Nimodipine-treated as well as parathyroidectomied animals showed significantly fewer hypertensive cerebral lesions."1.28Therapy of diseased stroke-prone spontaneously hypertensive rats with nimodipine. ( Kazda, S; Lenz, P; Luckhaus, G; Stasch, JP, 1990)
"The nimodipine-treated animals, however, showed only a slight diminution in the slope of the curve but no real plateau, indicating impairment of CBF autoregulation."1.27The influence of nimodipine on cerebral blood flow autoregulation and blood-brain barrier. ( Gaab, MR; Höllerhage, HG; Walter, GF; Zumkeller, M, 1988)

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-199012 (21.82)18.7374
1990's18 (32.73)18.2507
2000's16 (29.09)29.6817
2010's7 (12.73)24.3611
2020's2 (3.64)2.80

Authors

AuthorsStudies
Steiger, HJ1
Ensner, R1
Andereggen, L1
Remonda, L1
Berberat, J1
Marbacher, S1
Liu, X1
Zhao, N1
Zeng, K1
Xiao, P1
Sheng, P1
Luo, X1
Wang, Y2
McIlroy, E1
Sethuraman, R1
Woograsingh, R1
Nelson-Piercy, C1
Gilbert-Kawai, E1
Elstner, M1
Linn, J1
Müller-Schunk, S1
Straube, A1
Li, H1
Zhao, WM1
Han, YX1
Hassan, N1
Ali, M1
Ali, J1
Bakhru, A1
Atlas, RO1
Field, DK1
Kleinig, TJ1
Thompson, PD1
Kimber, TE1
Chatterjee, N1
Domoto-Reilly, K1
Fecci, PE1
Schwamm, LH1
Singhal, AB1
Han, YY1
Gui, W1
Zhu, J1
Liu, YM1
Wang, K1
Koenig, MA1
Yingling, DR1
Utter, G1
Vengalil, S1
Mason, B1
Macdonald, RL1
Rosengart, A1
Huo, D1
Karrison, T1
Liao, YC1
Fuh, JL1
Lirng, JF1
Lu, SR1
Wu, ZA1
Wang, SJ1
Inzitari, D2
Lamassa, M1
Pantoni, L1
Basile, AM1
Liang, B1
Poggesi, A1
Naskrent, M1
Mielcarek, J1
Tavernier, B1
Decamps, F1
Vega, E1
Poidevin, P1
Verdin, M1
Riegel, B1
Kamath, S1
Gadhinglajkar, SV1
Engberding, R1
Bender, F1
Gülker, H1
Specker, E1
Molinski, M1
Svendgaard, NA2
Brismar, J2
Delgado, T2
Egund, N1
Owman, C2
Rodacki, MA1
Sahlin, C2
Salford, LG2
Breuel, HP1
Mück, W1
Heine, PR1
Schmage, N1
Niklaus, H1
Kuhlmann, J1
Luiten, PG1
de Jong, GI1
Schuurman, T1
Weir, B1
MacDonald, L1
Ueda, M1
Masui, M1
Kawakami, M1
Matsunaga, K1
Gemba, T1
Ninomiya, M1
Nakano, A1
Torii, M1
Adachi, I1
Ito, H1
Roine, RO1
Anthony, J1
Mantel, G1
Johanson, R1
Dommisse, J1
Karadimov, D1
Alekhin, MN1
Sedov, VP1
Botsina, GI1
Sidorenko, BA1
Nosenko, EM1
Dennis, GC1
Welch, B1
Cole, AN1
Mendoza, R1
Morgan, J1
Epps, J1
Bernard, E1
St Louis, P1
Meneses, A2
Terrón, JA1
Ibarra, M1
Hong, E2
Morgan, MK1
Sekhon, LH1
Finfer, S1
Grinnell, V1
Bolte, AC1
van Geijn, HP1
Dekker, GA1
Sabbatini, M2
Tomassoni, D2
Amenta, F2
Ahmed, N1
Wahlgren, G1
Télez, M1
Martínez, B1
Criado, B1
Ortega, B1
Peñagarikano, O1
Flores, P1
Ortiz-Lastra, E1
Arrieta, I1
Boonen, HC1
De Mey, JG1
Brandt, L1
Säveland, H1
Romner, B1
Ryman, T1
Zhao, F2
Hermsmeyer, K1
Hatton, DA1
Karanja, N1
McCarron, D1
Lenz, P1
Luckhaus, G1
Stasch, JP1
Kazda, S1
Wang, W3
Yu, XH1
Lin, GZ1
Xu, ZK1
Dong, SM1
Dong, XF1
Wang, SY1
Liu, LS2
Garthoff, B1
Bellemann, P1
Zhao, Y1
Lei, YP1
Zhang, XE1
Jin, L1
Thorén, P1
Westling, H1
Skarphedinsson, JO1
Müller, H1
Kafurke, H1
Marck, P1
Zierski, J1
Hempelmann, G2
Höllerhage, HG1
Gaab, MR1
Zumkeller, M1
Walter, GF1
Pellettieri, L1
Bolander, H1
Carlsson, H1
Sjölander, U1
Boldt, J1
von Bormann, B1
Kling, D1
Ratthey, K1
Moosdorf, R1
Kazner, E1
Sprung, C1
Adelt, D1
Ammerer, HP1
Karnick, R1
Baumann, H1
Böker, DK1
Grotenhuis, JA1
Jaksche, H1
Istaitih, AR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
MRI Evaluation of Nidus Occlusion After Gamma Knife Radiosurgery of Cerebral Arteriovenous Malformations - A Prospective Preliminary Study[NCT03995823]50 participants (Anticipated)Observational2019-07-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for nimodipine and Blood Pressure, High

ArticleYear
A case of postpartum cerebral angiitis and review of the literature.
    Archives of gynecology and obstetrics, 2011, Volume: 283, Issue:3

    Topics: Adult; Antihypertensive Agents; Cerebral Angiography; Female; Humans; Hypertension; Migraine Disorde

2011
Management of delayed cerebral ischemia after subarachnoid hemorrhage.
    Continuum (Minneapolis, Minn.), 2012, Volume: 18, Issue:3

    Topics: Angioplasty, Balloon; Brain Ischemia; Calcium Channel Blockers; Cardiovascular Agents; Cerebral Angi

2012
Calcium channel blockers and stroke.
    Aging clinical and experimental research, 2005, Volume: 17, Issue:4 Suppl

    Topics: Aged; Antihypertensive Agents; Atherosclerosis; Calcium Channel Blockers; Dementia, Vascular; Humans

2005
Cerebrovascular, neuronal, and behavioral effects of long-term Ca2+ channel blockade in aging normotensive and hypertensive rat strains.
    Annals of the New York Academy of Sciences, 1994, Dec-15, Volume: 747

    Topics: Aging; Animals; Behavior, Animal; Blood-Brain Barrier; Brain; Calcium; Calcium Channel Blockers; Cal

1994
Cerebral vasospasm.
    Clinical neurosurgery, 1993, Volume: 40

    Topics: Aneurysm, Ruptured; Blood Pressure; Blood Volume; Brain Ischemia; Catheterization; Cerebral Infarcti

1993
Management and monitoring of severe preeclampsia.
    European journal of obstetrics, gynecology, and reproductive biology, 2001, Volume: 96, Issue:1

    Topics: Adrenal Cortex Hormones; Antihypertensive Agents; Blood Pressure Determination; Female; Fetal Diseas

2001

Trials

8 trials available for nimodipine and Blood Pressure, High

ArticleYear
[Effect of an integrative medical regimen on levels of vascular endothelial function and hypersensitive C-reactive protein in elderly patients with isolated systolic hypertension].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2009, Volume: 29, Issue:2

    Topics: Aged; C-Reactive Protein; Double-Blind Method; Drug Therapy, Combination; Drugs, Chinese Herbal; End

2009
Factors associated with the development of vasospasm after planned surgical treatment of aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2003, Volume: 99, Issue:4

    Topics: Adult; Aged; Combined Modality Therapy; Double-Blind Method; Drug Therapy, Combination; Female; Huma

2003
Therapy of vascular dementias.
    Archives of gerontology and geriatrics. Supplement, 2004, Issue:9

    Topics: Aged; Brain; Cognition Disorders; Dementia, Vascular; Double-Blind Method; Humans; Hypertension; Int

2004
[Clinical observation of the effect of xinmaitong tablet on hypertension].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2005, Volume: 28, Issue:7

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Drug Combinations; Drugs, Chinese Herbal; Female;

2005
The influence of nimodipine on hemodynamic parameters and peak and trough plasma concentrations of nifedipine chronically administered to elderly hypertensive patients.
    International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:2

    Topics: Aged; Blood Pressure; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Drug Int

1995
High initial blood pressure after acute stroke is associated with poor functional outcome.
    Journal of internal medicine, 2001, Volume: 249, Issue:5

    Topics: Acute Disease; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Tri

2001
Effect of treatment with nimodipine in patients with mild and moderate essential hypertension.
    Journal of human hypertension, 1990, Volume: 4, Issue:2

    Topics: Adult; Aged; Humans; Hypertension; Middle Aged; Nimodipine

1990
[Hemodynamic effects in high-dose infusion of nimodipine, a new calcium antagonist].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1986, Volume: 21, Issue:5

    Topics: Coronary Artery Bypass; Coronary Disease; Dose-Response Relationship, Drug; Hemodynamics; Humans; Hy

1986

Other Studies

41 other studies available for nimodipine and Blood Pressure, High

ArticleYear
Hemodynamic response and clinical outcome following intravenous milrinone plus norepinephrine-based hyperdynamic hypertensive therapy in patients suffering secondary cerebral ischemia after aneurysmal subarachnoid hemorrhage.
    Acta neurochirurgica, 2022, Volume: 164, Issue:3

    Topics: Brain Ischemia; Cerebral Infarction; Hemodynamics; Humans; Hypertension; Milrinone; Nimodipine; Nore

2022
Effects of nimodipine combined with betahistine on CRP and other inflammatory cytokines and vascular endothelial function in patients with hypertensive cerebral vasospasm.
    Clinical hemorheology and microcirculation, 2020, Volume: 75, Issue:3

    Topics: Aged; Antihypertensive Agents; Betahistine; C-Reactive Protein; Cytokines; Female; Humans; Hypertens

2020
Severe Postpartum Headache and Hypertension Caused by Reversible Cerebral Vasoconstriction Syndrome: A Case Report.
    A & A case reports, 2017, Nov-15, Volume: 9, Issue:10

    Topics: Adult; Anesthesia, Epidural; Brain Diseases; Female; Headache; Humans; Hypertension; Magnetic Resona

2017
Reversible cerebral vasoconstriction syndrome: a complicated clinical course treated with intra-arterial application of nimodipine.
    Cephalalgia : an international journal of headache, 2009, Volume: 29, Issue:6

    Topics: Brain; Cerebral Angiography; Female; Headache Disorders, Primary; Humans; Hyperlipidemias; Hypertens

2009
Development and evaluation of novel buccoadhesive wafers of nimodipine for treatment of hypertension.
    Drug delivery, 2010, Volume: 17, Issue:2

    Topics: Acrylic Resins; Adhesiveness; Administration, Buccal; Animals; Antihypertensive Agents; Biological A

2010
Reversible cerebral vasoconstriction, internal carotid artery dissection and renal artery stenosis.
    Cephalalgia : an international journal of headache, 2010, Volume: 30, Issue:8

    Topics: Adult; Antihypertensive Agents; Brain; Carotid Artery, Internal, Dissection; Cerebrovascular Circula

2010
Licorice-associated reversible cerebral vasoconstriction with PRES.
    Neurology, 2010, Nov-23, Volume: 75, Issue:21

    Topics: Administration, Oral; Brain; Cerebral Angiography; Cerebrovascular Circulation; Cerebrovascular Diso

2010
Thunderclap headache triggered by micturition: responsive to nimodipine.
    The journal of headache and pain, 2011, Volume: 12, Issue:6

    Topics: Antihypertensive Agents; Female; Headache Disorders, Primary; Humans; Hypertension; Middle Aged; Nim

2011
Calcium channel blocker, nimodipine, for the treatment of bipolar disorder during pregnancy.
    American journal of obstetrics and gynecology, 2002, Volume: 187, Issue:6

    Topics: Adult; Bipolar Disorder; Calcium Channel Blockers; Diabetes Insipidus, Nephrogenic; Female; Gestatio

2002
Bathing headache: a variant of idiopathic thunderclap headache.
    Cephalalgia : an international journal of headache, 2003, Volume: 23, Issue:9

    Topics: Adult; Baths; Brain Infarction; Cerebellar Diseases; Cerebellum; Cerebral Arteries; Female; Headache

2003
The effect of ionizing radiation of 1,4-dihydropyridine derivatives in the solid state.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2007, Volume: 67, Issue:1

    Topics: Calcium Channel Blockers; Dihydropyridines; Electron Spin Resonance Spectroscopy; Felodipine; Gamma

2007
[Systemic treatments of the vasospasm].
    Annales francaises d'anesthesie et de reanimation, 2007, Volume: 26, Issue:11

    Topics: Hemodilution; Hemodynamics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hy

2007
Can changes in BIS provide clue to lower limit of cerebral autoregulation?
    Journal of neurosurgical anesthesiology, 2008, Volume: 20, Issue:2

    Topics: Adrenergic alpha-Agonists; Anesthesia, General; Antihypertensive Agents; Blood Pressure; Cerebrovasc

2008
[Hemodynamic effects of the new calcium antagonist nimodipine in normal and increased blood pressure].
    Zeitschrift fur Kardiologie, 1984, Volume: 73, Issue:8

    Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Dose-Response Relationship, D

1984
Late cerebral arterial spasm: the cerebrovascular response to hypercapnia, induced hypertension and the effect of nimodipine on blood flow autoregulation in experimental subarachnoid hemorrhage in primates.
    General pharmacology, 1983, Volume: 14, Issue:1

    Topics: Animals; Calcium Channel Blockers; Cerebral Angiography; Cerebrovascular Circulation; Electroencepha

1983
Pharmacological studies on a new dihydrothienopyridine calcium antagonist. 4th communication: prophylactic and therapeutic effects of S-(+)-methyl-4,7-dihydro-3-isobutyl-6-methyl-4-(3-nitrophenyl)thieno[2, 3- b]pyridine-5-carboxylate in stroke-prone spont
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:12

    Topics: Animals; Behavior, Animal; Blood Pressure; Body Weight; Brain; Calcium Channel Blockers; Cerebrovasc

1993
Nimodipine in patients with heart disease.
    Circulation, 1996, Apr-01, Volume: 93, Issue:7

    Topics: Antihypertensive Agents; Calcium Channel Blockers; Cerebrovascular Disorders; Clinical Trials as Top

1996
The haemodynamic and respiratory effects of intravenous nimodipine used in the treatment of eclampsia.
    British journal of obstetrics and gynaecology, 1996, Volume: 103, Issue:6

    Topics: Adult; Blood Pressure; Eclampsia; Female; Hemodynamics; Humans; Hypertension; Infusions, Intravenous

1996
[Controlled hypotension against a background of nimodipine during an operation on neurosurgical patients with hypertension].
    Khirurgiia, 1995, Volume: 48, Issue:5

    Topics: Adolescent; Adult; Anesthesia, General; Antihypertensive Agents; Hemodynamics; Humans; Hypertension;

1995
[Effect of nimodipine in the diastolic function of the left ventricle in patients with essential hypertension and atherosclerotic circulatory encephalopathy].
    Klinicheskaia meditsina, 1996, Volume: 74, Issue:8

    Topics: Administration, Oral; Aged; Calcium Channel Blockers; Diastole; Female; Hemodynamics; Humans; Hypert

1996
Subarachnoid hemorrhage in the African-American population: a cooperative study.
    Journal of the National Medical Association, 1997, Volume: 89, Issue:2

    Topics: Aminocaproates; Antifibrinolytic Agents; Black People; Brain Ischemia; Calcium Channel Blockers; Coh

1997
Effects of nimodipine on learning in normotensive and spontaneously hypertensive rats.
    Behavioural brain research, 1997, Volume: 85, Issue:1

    Topics: Aging; Animals; Blood Pressure; Body Weight; Calcium Channel Blockers; Conditioning, Operant; Heart

1997
Spontaneously hypertensive rats: a potential model to identify drugs for treatment of learning disorders.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:4

    Topics: Aging; Analysis of Variance; Animals; Blood Pressure; Calcium Channel Blockers; Cognition Disorders;

1998
Delayed neurological deterioration following resection of arteriovenous malformations of the brain.
    Journal of neurosurgery, 1999, Volume: 90, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Aneurysm; Anticoagulants; Antihypertensive Agents; Asp

1999
Influence of treatment with Ca(2+) antagonists on cerebral vasculature of spontaneously hypertensive rats.
    Mechanisms of ageing and development, 2001, Volume: 122, Issue:8

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain; Calcium Channel Blockers; Cerebrovascular C

2001
Evaluation of the cytogenetic damage induced by the antihypertensive drug nimodipine in human lymphocytes.
    Mutagenesis, 2001, Volume: 16, Issue:4

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Cells, Cultured; Centromere; Female; Humans; Hyper

2001
Hypertensive brain damage: comparative evaluation of protective effect of treatment with dihydropyridine derivatives in spontaneously hypertensive rats.
    Mechanisms of ageing and development, 2001, Volume: 122, Issue:16

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain; Brain Injuries; Calcium Channel Blockers; D

2001
Increased calcium sensitivity in isolated resistance arteries from spontaneously hypertensive rats: effects of dihydropyridines.
    European journal of pharmacology, 1990, Apr-25, Volume: 179, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Does nimodipine eliminate arterial hypertension as a prognostic risk factor in subarachnoid haemorrhage?
    British journal of neurosurgery, 1991, Volume: 5, Issue:5

    Topics: Adolescent; Adult; Aged; Female; Humans; Hypertension; Intracranial Aneurysm; Ischemic Attack, Trans

1991
[Clinical studies on the improvement of failing memory by nimodipine].
    Zhonghua yi xue za zhi, 1990, Volume: 70, Issue:5

    Topics: Epinephrine; Female; Humans; Hypertension; Male; Memory Disorders; Middle Aged; Neuropsychological T

1990
Effects of dietary calcium on nimodipine-sensitive calcium channel function in stroke-prone spontaneously hypertensive rats.
    Stroke, 1990, Volume: 21, Issue:12 Suppl

    Topics: Animals; Blood Pressure; Calcium Channels; Calcium, Dietary; Cells, Cultured; Cerebrovascular Disord

1990
Therapy of diseased stroke-prone spontaneously hypertensive rats with nimodipine.
    Stroke, 1990, Volume: 21, Issue:12 Suppl

    Topics: Aging; Animals; Brain; Calcium; Cerebrovascular Disorders; Creatinine; Hypertension; Kidney; Male; M

1990
Effects of salt loading and nitrendipine on dihydropyridine receptors in hypertensive rats.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 10

    Topics: Animals; Blood Pressure; Brain; Calcium Channel Blockers; Calcium Channels; Hypertension; Membranes;

1987
Calcium antagonists in prevention of hypertension and stroke in stroke-prone spontaneously hypertensive rats.
    Chinese medical journal, 1989, Volume: 102, Issue:2

    Topics: Animals; Calcium Channel Blockers; Cerebrovascular Disorders; Female; Hypertension; Male; Nifedipine

1989
[Effects of nimodipine on blood pressure and cardiac function in hypertensive patients].
    Zhonghua xin xue guan bing za zhi, 1989, Volume: 17, Issue:6

    Topics: Adult; Aged; Blood Pressure; Female; Heart; Humans; Hypertension; Male; Middle Aged; Nimodipine; Ran

1989
Effect of the calcium antagonists felodipine and nimodipine on cortical blood flow in the spontaneously hypertensive rat.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:4

    Topics: Animals; Blood Pressure; Cerebral Cortex; Felodipine; Homeostasis; Hydrogen; Hypertension; Male; Nim

1989
Interactions between nimodipine and general anaesthesia--clinical investigations in 124 patients during neurosurgical operations.
    Acta neurochirurgica. Supplementum, 1988, Volume: 45

    Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthetics; Blood Pressure; Drug Interactions; Humans;

1988
The influence of nimodipine on cerebral blood flow autoregulation and blood-brain barrier.
    Journal of neurosurgery, 1988, Volume: 69, Issue:6

    Topics: Animals; Blood Pressure; Blood-Brain Barrier; Cerebrovascular Circulation; Electrodes; Evans Blue; H

1988
Nimodipine treatment of selected good-risk patients with subarachnoid hemorrhage: no significant difference between present and historical results.
    Surgical neurology, 1988, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Brain Ischemia; Child; Child, Preschool; Follow-Up Studies; Humans; Hypertension;

1988
Cerebrovascular and metabolic changes during the delayed vasospasm following experimental subarachnoid hemorrhage in baboons, and treatment with a calcium antagonist.
    Brain research, 1987, Feb-17, Volume: 403, Issue:2

    Topics: Animals; Blood Flow Velocity; Cerebral Angiography; Cerebral Arteries; Disease Models, Animal; Femal

1987
Clinical experience with nimodipine in the prophylaxis of neurological deficits after subarachnoid hemorrhage.
    Neurochirurgia, 1985, Volume: 28 Suppl 1

    Topics: Adult; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Intracran

1985