nimodipine has been researched along with Bipolar Disorder in 16 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bipolar disorder in pregnancy was treated with nimodipine, because of lithium-induced nephrogenic diabetes insipidus." | 7.71 | Calcium channel blocker, nimodipine, for the treatment of bipolar disorder during pregnancy. ( Mason, B; Utter, G; Vengalil, S; Yingling, DR, 2002) |
| "Preliminary evidence suggests that nimodipine, an L-type calcium channel blocker, is effective in treating some patients with rapidly cycling affective disorders and some phases of Alzheimer's disease, i." | 5.08 | Nimodipine increases CSF somatostatin in affectively ill patients. ( Davis, CL; George, MS; Pazzaglia, PJ; Post, RM; Rubinow, DR, 1995) |
| "Bipolar disorder in pregnancy was treated with nimodipine, because of lithium-induced nephrogenic diabetes insipidus." | 3.71 | Calcium channel blocker, nimodipine, for the treatment of bipolar disorder during pregnancy. ( Mason, B; Utter, G; Vengalil, S; Yingling, DR, 2002) |
| "This is a single case report of an open trial of nimodipine, a dihydropyridine-type calcium antagonist, in the treatment of a 13-year-old boy with refractory, ultradian rapid cycling, bipolar disorder type I." | 3.70 | Nimodipine treatment of an adolescent with ultradian cycling bipolar affective illness. ( Davanzo, PA; Kleiner, J; Krah, N; McCracken, J, 1999) |
| "2." | 1.29 | Combined treatment with lithium and nimodipine in a bipolar I manic syndrome. ( Berger, M; Grunze, H; Walden, J; Wolf, R, 1996) |
| " When the calcium antagonist nimodipine was given at a dosage quickly escalated to 360 mg daily, the patient could be discharged in a state of complete remission after 26 days." | 1.29 | [Phase prevention in bipolar affective disorder with nimodipine. A case report]. ( Berger, M; Hellwig, B; Hesslinger, B; Riedel, H; Walden, J, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (56.25) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cipriani, A | 1 |
| Saunders, K | 1 |
| Attenburrow, MJ | 1 |
| Stefaniak, J | 1 |
| Panchal, P | 1 |
| Stockton, S | 1 |
| Lane, TA | 1 |
| Tunbridge, EM | 1 |
| Geddes, JR | 1 |
| Harrison, PJ | 1 |
| De León, OA | 1 |
| Yingling, DR | 1 |
| Utter, G | 1 |
| Vengalil, S | 1 |
| Mason, B | 1 |
| Kidd, PM | 1 |
| Goodnick, PJ | 2 |
| Pazzaglia, PJ | 3 |
| Post, RM | 3 |
| Ketter, TA | 2 |
| George, MS | 3 |
| Marangell, LB | 2 |
| Rubinow, DR | 1 |
| Davis, CL | 1 |
| Grunze, H | 1 |
| Walden, J | 2 |
| Wolf, R | 1 |
| Berger, M | 2 |
| Hesslinger, B | 1 |
| Riedel, H | 1 |
| Hellwig, B | 1 |
| Callahan, AM | 1 |
| Frye, MA | 1 |
| Kimbrell, TA | 1 |
| Leverich, GS | 1 |
| Cora-Locatelli, G | 1 |
| Luckenbaugh, D | 1 |
| Davanzo, PA | 1 |
| Krah, N | 1 |
| Kleiner, J | 1 |
| McCracken, J | 1 |
| Levy, NA | 1 |
| Janicak, PG | 1 |
| Dubovsky, SL | 1 |
| Manna, V | 1 |
| Brunet, G | 1 |
| Cerlich, B | 1 |
| Robert, P | 1 |
| Dumas, S | 1 |
| Souetre, E | 1 |
| Darcourt, G | 1 |
4 reviews available for nimodipine and Bipolar Disorder
| Article | Year |
|---|---|
A systematic review of calcium channel antagonists in bipolar disorder and some considerations for their future development.
Topics: Bipolar Disorder; Calcium Channel Blockers; Calcium Channels, L-Type; Double-Blind Method; Humans; I | 2016 |
Bipolar disorder and cell membrane dysfunction. Progress toward integrative management.
Topics: Adolescent; Adult; Bipolar Disorder; Cell Membrane; Child; Humans; Nimodipine; Psychotherapy; Psycho | 2004 |
Calcium channel antagonists for the treatment of bipolar disorder.
Topics: Antimanic Agents; Bipolar Disorder; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Drug T | 2000 |
Rapid cycling bipolar disease: new concepts and treatments.
Topics: Anticonvulsants; Bipolar Disorder; Calcium; Calcium Channel Blockers; Carbamazepine; Combined Modali | 2001 |
5 trials available for nimodipine and Bipolar Disorder
| Article | Year |
|---|---|
Preliminary controlled trial of nimodipine in ultra-rapid cycling affective dysregulation.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; | 1993 |
Nimodipine increases CSF somatostatin in affectively ill patients.
Topics: Adult; Bipolar Disorder; Calcium Channel Blockers; Female; Humans; Male; Middle Aged; Mood Disorders | 1995 |
Nimodipine monotherapy and carbamazepine augmentation in patients with refractory recurrent affective illness.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Calcium Channel Blockers; Carbamazepine; Depressive Disor | 1998 |
[Bipolar affective disorders and role of intraneuronal calcium. Therapeutic effects of the treatment with lithium salts and/or calcium antagonist in patients with rapid polar inversion].
Topics: Adult; Affect; Bipolar Disorder; Calcium; Female; Humans; Lithium; Male; Neurons; Nimodipine; Salts | 1991 |
Open trial of a calcium antagonist, nimodipine, in acute mania.
Topics: Acute Disease; Adult; Bipolar Disorder; Clinical Trials as Topic; Female; Humans; Middle Aged; Nimod | 1990 |
7 other studies available for nimodipine and Bipolar Disorder
| Article | Year |
|---|---|
Response to nimodipine in ultradian bipolar cycling after amygdalohippocampectomy.
Topics: Antimanic Agents; Bipolar Disorder; Calcium Channel Blockers; Carbamazepine; Depressive Disorder; Fe | 2012 |
Calcium channel blocker, nimodipine, for the treatment of bipolar disorder during pregnancy.
Topics: Adult; Bipolar Disorder; Calcium Channel Blockers; Diabetes Insipidus, Nephrogenic; Female; Gestatio | 2002 |
Nimodipine treatment of rapid cycling bipolar disorder.
Topics: Bipolar Disorder; Female; Humans; Male; Middle Aged; Nimodipine; Treatment Outcome | 1995 |
Combined treatment with lithium and nimodipine in a bipolar I manic syndrome.
Topics: Adult; Bipolar Disorder; Brief Psychiatric Rating Scale; Female; Humans; Lithium; Nimodipine; Time F | 1996 |
[Phase prevention in bipolar affective disorder with nimodipine. A case report].
Topics: Bipolar Disorder; Calcium Channel Blockers; Depressive Disorder; Dose-Response Relationship, Drug; D | 1996 |
Nimodipine treatment of an adolescent with ultradian cycling bipolar affective illness.
Topics: Activity Cycles; Adolescent; Antimanic Agents; Bipolar Disorder; Calcium Channel Blockers; Humans; M | 1999 |
The use of nimodipine in the treatment of mood disorders.
Topics: Activity Cycles; Bipolar Disorder; Calcium Channel Blockers; Catecholamines; Humans; Mood Disorders; | 2000 |