nimodipine has been researched along with Asystole in 19 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One hundred fifty-five consecutive patients resuscitated after out-of-hospital ventricular fibrillation by a physician-manned advanced life support unit were randomly assigned to receive nimodipine or placebo at a dosage of 10 micrograms/kg as an intravenous injection immediately after restoration of spontaneous circulation, followed by an infusion of 0." | 9.06 | Nimodipine after resuscitation from out-of-hospital ventricular fibrillation. A placebo-controlled, double-blind, randomized trial. ( Kajaste, S; Kaste, M; Kinnunen, A; Nikki, P; Roine, RO; Sarna, S, 1990) |
| "The presence of cerebral infarcts, leukoaraiosis, atrophy, and edema on ultra-low-field MRI was assessed in 88 community volunteers and 52 cardiac arrest survivors enrolled in a placebo-controlled, randomized, double-blind trial of nimodipine in out-of-hospital ventricular fibrillation." | 5.07 | Magnetic resonance imaging findings associated with cardiac arrest. ( Erkinjuntti, T; Kaste, M; Raininko, R; Roine, RO; Ylikoski, A, 1993) |
| "Placebo-controlled, randomized, double-blind trial of nimodipine compared with placebo in out-of-hospital ventricular fibrillation." | 5.07 | Neuropsychological sequelae of cardiac arrest. ( Kajaste, S; Kaste, M; Roine, RO, 1993) |
| "One hundred fifty-five consecutive patients resuscitated after out-of-hospital ventricular fibrillation by a physician-manned advanced life support unit were randomly assigned to receive nimodipine or placebo at a dosage of 10 micrograms/kg as an intravenous injection immediately after restoration of spontaneous circulation, followed by an infusion of 0." | 5.06 | Nimodipine after resuscitation from out-of-hospital ventricular fibrillation. A placebo-controlled, double-blind, randomized trial. ( Kajaste, S; Kaste, M; Kinnunen, A; Nikki, P; Roine, RO; Sarna, S, 1990) |
| "This study presents 39 out-of-hospital cardiac arrests resuscitated with success." | 2.67 | Early effects of nimodipine on intracranial and cerebral perfusion pressures in cerebral anoxia after out-of-hospital cardiac arrest. ( Bancalari, G; Garcia-Darennes, F; Gaussorgues, P; Gueugniaud, PY; Petit, P; Robert, D; Roux, H, 1990) |
| "Patients suffering from critical illnesses like cardiac arrest with resuscitation and hypovolemic shock often are in need of medication." | 2.41 | [Pharmacology in critical illness]. ( Buylaert, WA, 2001) |
| " In these experiments, we started the administration of nimodipine before the induction of global brain ischemia, used 2 different dosage regimens and provided prolonged drug administration after restoration of cerebral blood flow in order to create optimal circumstances for a cerebroprotective effect to be detected." | 1.29 | Pharmacological influences on cardiopulmonary arrest-related brain damage in the rat. ( Calle, PA, 1993) |
| "Brain damage after resuscitation from cardiac arrest is believed to be related to calcium influx in ischaemic neurons and to postischaemic calcium-dependent vasospasm." | 1.28 | Nimodipine has no beneficial effect on neurological outcome in a cardiopulmonary arrest model in the rat. ( Bogaert, MG; Buylaert, WA; Calle, PA; De Ridder, L, 1990) |
| "Nimodipine was given as a bolus injection followed by a maintenance infusion." | 1.27 | Influence of cardiopulmonary resuscitation on plasma concentrations of nimodipine in the dog. ( Buylaert, WA; Calle, PA; Huyghens, LP; Rosseel, MT, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (36.84) | 18.7374 |
| 1990's | 11 (57.89) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xie, Y | 1 |
| Zacharias, E | 1 |
| Hoff, P | 1 |
| Tegtmeier, F | 1 |
| Nash, SD | 1 |
| Patt, MV | 1 |
| Schindler, I | 1 |
| Steltzer, H | 1 |
| Weindlmayr-Goettel, M | 1 |
| Steinbereithner, K | 1 |
| Roine, RO | 4 |
| Raininko, R | 1 |
| Erkinjuntti, T | 1 |
| Ylikoski, A | 1 |
| Kaste, M | 4 |
| Kajaste, S | 2 |
| Calle, PA | 4 |
| Buylaert, WA | 5 |
| Tateishi, A | 2 |
| Scheller, MS | 2 |
| Drummond, JC | 2 |
| Zornow, MH | 2 |
| Grafe, MR | 2 |
| Fleischer, JE | 2 |
| Shapiro, HM | 2 |
| Bogaert, MG | 3 |
| De Ridder, L | 2 |
| Gueugniaud, PY | 1 |
| Gaussorgues, P | 1 |
| Garcia-Darennes, F | 1 |
| Bancalari, G | 1 |
| Roux, H | 1 |
| Robert, D | 1 |
| Petit, P | 1 |
| Kinnunen, A | 2 |
| Nikki, P | 2 |
| Sarna, S | 1 |
| Huyghens, LP | 2 |
| Corne, L | 1 |
| Rosseel, MT | 2 |
| Prough, DS | 1 |
| Furberg, CD | 1 |
| Forsman, M | 1 |
| Aarseth, HP | 1 |
| Nordby, HK | 1 |
| Skulberg, A | 1 |
| Steen, PA | 2 |
| Gisvold, SE | 1 |
| Milde, JH | 1 |
| Newberg, LA | 1 |
| Scheithauer, BW | 1 |
| Lanier, WL | 1 |
| Michenfelder, JD | 1 |
1 review available for nimodipine and Asystole
| Article | Year |
|---|---|
[Pharmacology in critical illness].
Topics: Adrenergic Agonists; Anesthetics, Intravenous; Animals; Calcium Channel Blockers; Cardiopulmonary Re | 2001 |
5 trials available for nimodipine and Asystole
| Article | Year |
|---|---|
Magnetic resonance imaging findings associated with cardiac arrest.
Topics: Adult; Age Factors; Aged; Atrophy; Brain Edema; Cerebral Infarction; Double-Blind Method; Female; He | 1993 |
Neuropsychological sequelae of cardiac arrest.
Topics: Adult; Aged; Aged, 80 and over; Cognition; Depressive Disorder; Double-Blind Method; Female; Heart A | 1993 |
Early effects of nimodipine on intracranial and cerebral perfusion pressures in cerebral anoxia after out-of-hospital cardiac arrest.
Topics: Cerebrovascular Circulation; Heart Arrest; Humans; Hypoxia, Brain; Intracranial Pressure; Middle Age | 1990 |
Nimodipine after resuscitation from out-of-hospital ventricular fibrillation. A placebo-controlled, double-blind, randomized trial.
Topics: Aged; Brain Ischemia; Double-Blind Method; Female; Heart Arrest; Humans; Male; Middle Aged; Nimodipi | 1990 |
Effects of nimodipine on cerebral blood flow and cerebrospinal fluid pressure after cardiac arrest: correlation with neurologic outcome.
Topics: Aged; Cerebrospinal Fluid Pressure; Cerebrovascular Circulation; Consciousness; Female; Heart Arrest | 1989 |
13 other studies available for nimodipine and Asystole
| Article | Year |
|---|---|
Ion channel involvement in anoxic depolarization induced by cardiac arrest in rat brain.
Topics: Adenosine Triphosphate; Animals; Benzothiazoles; Calcium; Dizocilpine Maleate; Flunarizine; Glyburid | 1995 |
Sinus arrest after nimodipine treatment for a head injury.
Topics: Adult; Arrhythmia, Sinus; Electrocardiography; Heart Arrest; Humans; Ischemic Attack, Transient; Mal | 1994 |
Nimodipine after circulatory arrest: effects on oxygen delivery and consumption.
Topics: Animals; Blood Gas Analysis; Cardiopulmonary Resuscitation; Combined Modality Therapy; Disease Model | 1994 |
Pharmacological influences on cardiopulmonary arrest-related brain damage in the rat.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Butylene Glycols; Carotid Arteries; Heart Arrest; Liga | 1993 |
Failure of nimodipine to improve neurologic outcome after eighteen minutes of cardiac arrest in the cat.
Topics: Animals; Cats; Central Nervous System Diseases; Electroencephalography; Heart Arrest; Hemodynamics; | 1991 |
Nimodipine decreases resuscitability in a cardiopulmonary arrest model in the rat.
Topics: Animals; Central Nervous System Diseases; Heart Arrest; Nimodipine; Rats; Rats, Inbred Strains; Resu | 1991 |
Nimodipine has no beneficial effect on neurological outcome in a cardiopulmonary arrest model in the rat.
Topics: Animals; Blood Pressure; Cell Survival; Coronary Disease; Disease Models, Animal; Electrocardiograph | 1990 |
Plasma concentrations and haemodynamic effects of nimodipine in patients resuscitated after cardiac arrest.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Ethanol; Female; Heart Arrest; Heart Rate; Hemodynam | 1989 |
Nimodipine does not improve neurologic outcome after 14 minutes of cardiac arrest in cats.
Topics: Animals; Brain; Cats; Central Nervous System Diseases; Electroencephalography; Heart Arrest; Nimodip | 1989 |
Influence of cardiopulmonary resuscitation on plasma concentrations of nimodipine in the dog.
Topics: Animals; Antipyrine; Blood Pressure; Body Temperature; Dogs; Female; Heart Arrest; Male; Nimodipine; | 1987 |
Nimodipine and the "no-reflow phenomenon"--experimental triumph, clinical failure?
Topics: Cerebrovascular Circulation; Heart Arrest; Humans; Nimodipine; Reperfusion Injury | 1989 |
Safety and efficacy of nimodipine in resuscitation of patients outside hospital.
Topics: Community Health Services; Heart Arrest; Humans; Nimodipine; Resuscitation; Safety | 1987 |
Nimodipine improves outcome when given after complete cerebral ischemia in primates.
Topics: Animals; Brain; Brain Ischemia; Calcium Channel Blockers; Drug Evaluation, Preclinical; Electroencep | 1985 |