Page last updated: 2024-11-01

nimodipine and Arrhythmia

nimodipine has been researched along with Arrhythmia in 4 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Research Excerpts

ExcerptRelevanceReference
"Careful observation of blood pressure and heart rate in patients with subarachnoid hemorrhage during therapy with nimodipine showed that blood pressure decreases mainly in hypertensive patients during the first hours of therapy or when treatment is started immediately with 2 mg per hour instead of the recommended initial dose of 1 mg per hour."7.67Blood pressure and heart rate during treatment with nimodipine in patients with subarachnoid hemorrhage. ( Düdden, P; Dycka, J; Tettenborn, D; Volberg, E, 1985)
" We therefore decided to compare the influence of oral and intravenous administration of furnidipine, nifedipine, nitrendipine and nimodipine to examine their effects on hemodynamics and arrhythmias."3.78Anti-arrhythmic and hemodynamic effects of oxy nifedipine, oxy nimodipine, oxy nitrendipine and oxy nisoldipine. ( Krzemiński, TF; Mitręga, KA; Porc, M; Varghese, B, 2012)
"Careful observation of blood pressure and heart rate in patients with subarachnoid hemorrhage during therapy with nimodipine showed that blood pressure decreases mainly in hypertensive patients during the first hours of therapy or when treatment is started immediately with 2 mg per hour instead of the recommended initial dose of 1 mg per hour."3.67Blood pressure and heart rate during treatment with nimodipine in patients with subarachnoid hemorrhage. ( Düdden, P; Dycka, J; Tettenborn, D; Volberg, E, 1985)
"Bupivacaine is a local anesthetic frequently used in clinical practice, and cardiotoxicity is one of its severe side effects."1.30The effects of verapamil and nimodipine on bupivacaine-induced cardiotoxicity in rats: an in vivo and in vitro study. ( Adsan, H; Onaran, O; Tulunay, M, 1998)
" Three minutes after pretreatment, group 1 (n = 11), group 3 (n = 10), and their respective control groups (n = 11 and n = 9) received intravenous bupivacaine LD50 (median lethal dose)."1.28Nimodipine reduces the toxicity of intravenous bupivacaine in rats. ( Horn, JL; Hyman, SA; Kambam, JR; Kinney, WW; Skelley, CC, 1992)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mitręga, KA1
Varghese, B1
Porc, M1
Krzemiński, TF1
Adsan, H1
Tulunay, M1
Onaran, O1
Hyman, SA1
Kinney, WW1
Horn, JL1
Skelley, CC1
Kambam, JR1
Tettenborn, D1
Dycka, J1
Volberg, E1
Düdden, P1

Other Studies

4 other studies available for nimodipine and Arrhythmia

ArticleYear
Anti-arrhythmic and hemodynamic effects of oxy nifedipine, oxy nimodipine, oxy nitrendipine and oxy nisoldipine.
    Pharmacological research, 2012, Volume: 66, Issue:4

    Topics: Administration, Intravenous; Administration, Oral; Animals; Anti-Arrhythmia Agents; Arrhythmias, Car

2012
The effects of verapamil and nimodipine on bupivacaine-induced cardiotoxicity in rats: an in vivo and in vitro study.
    Anesthesia and analgesia, 1998, Volume: 86, Issue:4

    Topics: Anesthetics, Local; Animals; Arrhythmias, Cardiac; Blood Pressure; Bupivacaine; Calcium Channel Bloc

1998
Nimodipine reduces the toxicity of intravenous bupivacaine in rats.
    Anesthesia and analgesia, 1992, Volume: 74, Issue:6

    Topics: Animals; Apnea; Arrhythmias, Cardiac; Body Weight; Bupivacaine; Cardiovascular System; Drug Interact

1992
Blood pressure and heart rate during treatment with nimodipine in patients with subarachnoid hemorrhage.
    Neurochirurgia, 1985, Volume: 28 Suppl 1

    Topics: Arrhythmias, Cardiac; Blood Pressure; Brain Ischemia; Calcium Channel Blockers; Heart Rate; Humans;

1985