Page last updated: 2024-11-01

nimodipine and Aqueductal Stenosis

nimodipine has been researched along with Aqueductal Stenosis in 11 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Research Excerpts

ExcerptRelevanceReference
"Nimodipine is commonly used to improve neurological outcomes after subarachnoid hemorrhage."3.70Nimodipine-induced acute hypoxemia: case report. ( Coplin, WM; Devlin, JW; Murry, KR; Rengachary, SS; Wilson, RF, 2000)
"Nimodipine was given twice daily by subcutaneous injections."1.34Calcium antagonism in neonatal rats with kaolin-induced hydrocephalus. ( Del Bigio, MR; Khan, OH; McPhee, LC; Moddemann, LN, 2007)
"Nimodipine treatment prevented the declines in motor and cognitive behavior that were observed in untreated control rats."1.31Protective effect of nimodipine on behavior and white matter of rats with hydrocephalus. ( Del Bigio, MR; Massicotte, EM, 2001)
"The morbidity and mortality of cerebral vasospasm is significant."1.31Contemporary management of subarachnoid hemorrhage and vasospasm: the UIC experience. ( Alp, MS; Ausman, J; Charbel, F; Corsten, L; Debrun, G; Guppy, K; Misra, M; Raja, A; Roitberg, B, 2001)
"Early hydrocephalus is a risk factor of shunt-dependent late hydrocephalus (SDHC)."1.29Shunt-dependent hydrocephalus after subarachnoid haemorrhage and aneurysm surgery: timing of surgery is not a risk factor. ( Hernesniemi, J; Kari, A; Luukkonen, M; Niskanen, M; Puranen, M; Tapaninaho, A; Vapalahti, M, 1993)
"Nimodipine was administered to 269 of the 325 patients: intravenously in 218, orally in 15, and intravenously followed by orally in 36."1.28Overall outcome in aneurysmal subarachnoid hemorrhage. A prospective study from neurosurgical units in Sweden during a 1-year period. ( Algers, G; Brandt, L; Edner, G; Hillman, J; Jakobsson, KE; Säveland, H, 1992)
"The postoperative intracerebral hemorrhage occurred in 16 cases and seemed to be caused by one or more of the following events: cerebral infarction developed during the preoperative period, occlusion of the cerebral veins during the Sylvian dissection, cerebral retraction and/or sudden change of intracranial hemodynamics."1.28Surgery of intracranial aneurysms at Yonsei University: 780 cases. ( Lee, KC, 1991)
"Eight patients with normal-pressure hydrocephalus (NPH) were studied."1.28The effect of nimodipine on ICP and CBF in patients with normal-pressure hydrocephalus. ( Albeck, M; Gjerris, F; Schmidt, JF, 1990)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's4 (36.36)18.2507
2000's4 (36.36)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Hawkes, MA1
Hlavnicka, AA1
Wainsztein, NA1
Di Curzio, DL1
Mao, X1
Baker, A1
Del Bigio, MR3
Khan, OH1
McPhee, LC1
Moddemann, LN1
Tapaninaho, A1
Hernesniemi, J1
Vapalahti, M1
Niskanen, M1
Kari, A1
Luukkonen, M1
Puranen, M1
Devlin, JW1
Coplin, WM1
Murry, KR1
Rengachary, SS1
Wilson, RF1
Massicotte, EM1
Corsten, L1
Raja, A1
Guppy, K1
Roitberg, B1
Misra, M1
Alp, MS1
Charbel, F1
Debrun, G1
Ausman, J1
Säveland, H1
Hillman, J1
Brandt, L1
Edner, G1
Jakobsson, KE1
Algers, G1
Lee, KC1
Schmidt, JF1
Albeck, M1
Gjerris, F1
Gilsbach, JM1
Harders, AG1
Eggert, HR1
Hornyak, ME1

Other Studies

11 other studies available for nimodipine and Aqueductal Stenosis

ArticleYear
Reversible Cerebral Vasoconstriction Syndrome Responsive to Intravenous Milrinone.
    Neurocritical care, 2020, Volume: 32, Issue:1

    Topics: Adult; Angiography, Digital Subtraction; Aphasia, Broca; Brain Edema; Cerebral Hemorrhage; Computed

2020
Nimodipine treatment does not benefit juvenile ferrets with kaolin-induced hydrocephalus.
    Fluids and barriers of the CNS, 2018, May-03, Volume: 15, Issue:1

    Topics: Animals; Animals, Newborn; Brain; Calcium Channel Blockers; Disease Models, Animal; Dose-Response Re

2018
Calcium antagonism in neonatal rats with kaolin-induced hydrocephalus.
    Journal of child neurology, 2007, Volume: 22, Issue:10

    Topics: Animals; Animals, Newborn; Brain; Brain Damage, Chronic; Calcium Channel Blockers; Calcium Channels;

2007
Shunt-dependent hydrocephalus after subarachnoid haemorrhage and aneurysm surgery: timing of surgery is not a risk factor.
    Acta neurochirurgica, 1993, Volume: 123, Issue:3-4

    Topics: Adult; Aneurysm, Ruptured; Cerebrospinal Fluid Shunts; Combined Modality Therapy; Female; Humans; Hy

1993
Nimodipine-induced acute hypoxemia: case report.
    Neurosurgery, 2000, Volume: 47, Issue:5

    Topics: Acute Disease; Calcium Channel Blockers; Drug Administration Schedule; Humans; Hydrocephalus; Hypoxi

2000
Protective effect of nimodipine on behavior and white matter of rats with hydrocephalus.
    Journal of neurosurgery, 2001, Volume: 94, Issue:5

    Topics: Animals; Behavior, Animal; Calcium Channel Blockers; Cerebrovascular Circulation; Hydrocephalus; Maz

2001
Contemporary management of subarachnoid hemorrhage and vasospasm: the UIC experience.
    Surgical neurology, 2001, Volume: 56, Issue:3

    Topics: Algorithms; Angioplasty, Balloon; Calcium Channel Blockers; Catheterization; Cerebral Angiography; D

2001
Overall outcome in aneurysmal subarachnoid hemorrhage. A prospective study from neurosurgical units in Sweden during a 1-year period.
    Journal of neurosurgery, 1992, Volume: 76, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Female; Hemodilution; Humans; Hydrocephalus; Intr

1992
Surgery of intracranial aneurysms at Yonsei University: 780 cases.
    The Keio journal of medicine, 1991, Volume: 40, Issue:1

    Topics: Brain Ischemia; Cerebral Hemorrhage; Humans; Hydrocephalus; Intracranial Aneurysm; Nimodipine; Posto

1991
The effect of nimodipine on ICP and CBF in patients with normal-pressure hydrocephalus.
    Acta neurochirurgica, 1990, Volume: 102, Issue:1-2

    Topics: Aged; Aged, 80 and over; Blood Pressure; Cerebral Arteries; Cerebrovascular Circulation; Female; Hum

1990
Early aneurysm surgery: a 7 year clinical practice report.
    Acta neurochirurgica, 1988, Volume: 90, Issue:3-4

    Topics: Cerebral Angiography; Cerebrospinal Fluid Shunts; Humans; Hydrocephalus; Intracranial Aneurysm; Isch

1988