nimodipine has been researched along with Anoxia, Brain in 15 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute cerebral hypoxia causes rapid calcium shifts leading to neuronal damage and death." | 2.90 | Calcium channel blockade with nimodipine reverses MRI evidence of cerebral oedema following acute hypoxia. ( Douaud, G; Ezra, M; Garry, P; Kelly, M; Lamb, C; Okell, TW; Pattinson, KT; Rowland, MJ; Westbrook, J; Winkler, A; Wise, RG, 2019) |
| "This study presents 39 out-of-hospital cardiac arrests resuscitated with success." | 2.67 | Early effects of nimodipine on intracranial and cerebral perfusion pressures in cerebral anoxia after out-of-hospital cardiac arrest. ( Bancalari, G; Garcia-Darennes, F; Gaussorgues, P; Gueugniaud, PY; Petit, P; Robert, D; Roux, H, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 6 (40.00) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rowland, MJ | 1 |
| Ezra, M | 1 |
| Winkler, A | 1 |
| Garry, P | 1 |
| Lamb, C | 1 |
| Kelly, M | 1 |
| Okell, TW | 1 |
| Westbrook, J | 1 |
| Wise, RG | 1 |
| Douaud, G | 1 |
| Pattinson, KT | 1 |
| Li, H | 2 |
| Wei, C | 1 |
| Ke, J | 1 |
| Li, J | 1 |
| Xu, L | 1 |
| Liu, H | 1 |
| Li, S | 1 |
| Yang, M | 1 |
| Haile, M | 1 |
| Limson, F | 1 |
| Gingrich, K | 1 |
| Li, YS | 1 |
| Quartermain, D | 1 |
| Blanck, T | 1 |
| Bekker, A | 1 |
| Clincke, GH | 1 |
| Wauquier, A | 1 |
| Shukitt-Hale, B | 1 |
| Stillman, MJ | 1 |
| Levy, A | 1 |
| Devine, JA | 1 |
| Lieberman, HR | 1 |
| Wassmann, H | 2 |
| Moskopp, D | 2 |
| Woesler, B | 1 |
| Lücke, A | 1 |
| Speckmann, EJ | 2 |
| Köhling, R | 2 |
| Straub, H | 1 |
| Hülsmann, S | 2 |
| Greiner, C | 2 |
| Schmidinger, A | 1 |
| Wölfer, J | 1 |
| Gueugniaud, PY | 1 |
| Gaussorgues, P | 1 |
| Garcia-Darennes, F | 1 |
| Bancalari, G | 1 |
| Roux, H | 1 |
| Robert, D | 1 |
| Petit, P | 1 |
| Matyja, E | 1 |
| Kida, E | 1 |
| Stys, PK | 1 |
| Ransom, BR | 1 |
| Waxman, SG | 1 |
| Isaacson, RL | 1 |
| Renkawek, K | 2 |
| Lazarewicz, JW | 2 |
| Kass, IS | 1 |
| Cottrell, JE | 1 |
| Chambers, G | 1 |
| Shimizu, Y | 1 |
2 trials available for nimodipine and Anoxia, Brain
| Article | Year |
|---|---|
Calcium channel blockade with nimodipine reverses MRI evidence of cerebral oedema following acute hypoxia.
Topics: Adult; Brain Edema; Calcium; Calcium Channel Blockers; Calcium Signaling; Female; Humans; Hypoxia, B | 2019 |
Early effects of nimodipine on intracranial and cerebral perfusion pressures in cerebral anoxia after out-of-hospital cardiac arrest.
Topics: Cerebrovascular Circulation; Heart Arrest; Humans; Hypoxia, Brain; Intracranial Pressure; Middle Age | 1990 |
13 other studies available for nimodipine and Anoxia, Brain
| Article | Year |
|---|---|
Biomimetic synthesis and evaluation of histidine-derivative templated chiral mesoporous silica for improved oral delivery of the poorly water-soluble drug, nimodipine.
Topics: Administration, Oral; Animals; Biological Availability; Biomimetic Materials; Biomimetics; Calcium C | 2018 |
Nimodipine prevents transient cognitive dysfunction after moderate hypoxia in adult mice.
Topics: Animals; Attention; Blood Gas Analysis; Calcium Channel Blockers; Calcium Channels, L-Type; Cognitio | 2009 |
Pharmacological protection against hypoxia-induced effects on medium-term memory in a two-way avoidance paradigm.
Topics: Animals; Avoidance Learning; Calcium Channel Blockers; Cerebral Cortex; Cinnarizine; Dose-Response R | 1984 |
Nimodipine prevents the in vivo decrease in hippocampal extracellular acetylcholine produced by hypobaric hypoxia.
Topics: Acetylcholine; Altitude Sickness; Animals; Hippocampus; Hypoxia, Brain; Male; Microdialysis; Nimodip | 1993 |
Repetitive hypoxic exposure of brain slices and electrophysiological responses as an experimental model for investigation of cerebroprotective measurements.
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Cell Hypoxia; Electric Stimulation; Energy Metabo | 1996 |
Acute protective effect of nimodipine and dimethyl sulfoxide against hypoxic and ischemic damage in brain slices.
Topics: Animals; Brain; Brain Ischemia; Dimethyl Sulfoxide; Evoked Potentials; Guinea Pigs; Hypoxia-Ischemia | 2000 |
Protective effect of the calcium entry blocker nimodipine on hippocampal rat cultures submitted to anoxia.
Topics: Animals; Astrocytes; Cells, Cultured; Endoplasmic Reticulum; Hippocampus; Hypoxia, Brain; Microscopy | 1990 |
Effects of polyvalent cations and dihydropyridine calcium channel blockers on recovery of CNS white matter from anoxia.
Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Hypoxia, Brain; In Vitro Techniques; | 1990 |
Brain plasticity after damage.
Topics: Animals; Brain Damage, Chronic; Choline; Hippocampus; Hypoxia, Brain; Metyrapone; Neuronal Plasticit | 1990 |
Protective effect of the calcium entry blocker, nimodipine on cerebellar organotypic cultures submitted to anoxia.
Topics: Animals; Astrocytes; Cerebellum; Culture Media; Hypoxia, Brain; Microscopy, Electron; Nimodipine; Or | 1989 |
Nimodipine applied immediately after anoxia protects cerebellar cells in culture against injury.
Topics: Animals; Astrocytes; Cerebellum; Hypoxia, Brain; Nimodipine; Organ Culture Techniques; Rats; Time Fa | 1989 |
Magnesium and cobalt, not nimodipine, protect neurons against anoxic damage in the rat hippocampal slice.
Topics: Animals; Cobalt; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Magnesium; Male; Neurons; Nimodip | 1988 |
[Effect of the calcium entry blockers nicardipine and nimodipine on cerebral function following global anoxia in the rat].
Topics: Animals; Brain; Calcium Channel Blockers; Hypoxia, Brain; Male; Nicardipine; Nicotinic Acids; Nifedi | 1986 |