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nimodipine and Angiospasm, Intracranial

nimodipine has been researched along with Angiospasm, Intracranial in 189 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Research Excerpts

ExcerptRelevanceReference
"These results are consistent with a beneficial effect of locally delivered nimodipine (EG-1962) on SD after aSAH in more severely injured patients who are at risk of delayed cerebral ischemia related to SD."9.41Effect of Locally Delivered Nimodipine Microparticles on Spreading Depolarization in Aneurysmal Subarachnoid Hemorrhage. ( Alchbli, A; Carlson, AP; Hänggi, D; Macdonald, RL; Shuttleworth, CW, 2021)
"Our objective was to compare the effectiveness of intravenous and enteral nimodipine in preventing poor outcome from delayed cerebral ischemia in patients with subarachnoid hemorrhage."9.22A Comparison Between Enteral and Intravenous Nimodipine in Subarachnoid Hemorrhage: A Systematic Review and Network Meta-Analysis. ( Boscolo, A; Cacco, N; Carere, A; Correale, C; De Cassai, A; Diana, P; Disarò, L; Geraldini, F; Munari, M; Navalesi, P; Zampirollo, S, 2022)
"Fasudil is believed to be at least equally effective as nimodipine for the prevention of cerebral vasospasm and subsequent ischemic injury in patients undergoing surgery for subarachnoid hemorrhage (SAH)."9.15Efficacy and safety of fasudil in patients with subarachnoid hemorrhage: final results of a randomized trial of fasudil versus nimodipine. ( Guo, J; Mao, Y; Ren, Z; Wang, R; Wang, S; Xu, B; Zhang, X; Zhang, Y; Zhao, J; Zhao, K; Zhou, D; Zhou, L, 2011)
"The calcium antagonist nimodipine has been shown to reduce the incidence of ischemic complications following aneurysmal subarachnoid hemorrhage (SAH)."9.14Nimodipine in aneurysmal subarachnoid hemorrhage: a randomized study of intravenous or peroral administration. ( Cronqvist, M; Kronvall, E; Nilsson, OG; Romner, B; Säveland, H; Undrén, P, 2009)
"The efficacy of intra-arterial administration of nimodipine (IAN) in patients with severe vasospasm after aneurysmal subarachnoid hemorrhage (SAH) remains unproved."9.13Intra-arterial nimodipine for severe cerebral vasospasm after aneurysmal subarachnoid hemorrhage: influence on clinical course and cerebral perfusion. ( Beseoglu, K; Hänggi, D; Steiger, HJ; Turowski, B; Yong, M, 2008)
"The prophylactic use of nimodipine in patients with aneurysmal subarachnoid hemorrhage reduces the risk of ischemic brain damage."9.12Intravenous magnesium versus nimodipine in the treatment of patients with aneurysmal subarachnoid hemorrhage: a randomized study. ( Briegel, J; Kunz, M; Prueckner, S; Schmid-Elsaesser, R; Steiger, HJ; Zausinger, S, 2006)
" This randomized open trial with nimodipine as the control included 72 patients who underwent subarachnoid hemorrhage surgery for ruptured cerebral aneurysm of Hunt and Hess grades I to IV."9.12Effect of fasudil hydrochloride, a protein kinase inhibitor, on cerebral vasospasm and delayed cerebral ischemic symptoms after aneurysmal subarachnoid hemorrhage. ( Guo, J; Ren, Z; Wang, R; Wang, S; Xu, B; Zhao, J; Zhou, D; Zhou, L, 2006)
"Eleven patients with primary thunderclap headache (TCH) were treated with oral nimodipine 30 to 60 mg every 4 hours or IV nimodipine 0."9.11Nimodipine for treatment of primary thunderclap headache. ( Fuh, JL; Liao, YC; Lirng, JF; Lu, SR; Wang, SJ, 2004)
"Thirty consecutive patients under-going intracranial aneurysmal surgery were prospectively randomized into two groups: Isoflurane (group A, n = 15) and nimodipine (group B, n = 15)."9.11[The effect of intraoperative continuous nimodipine infusion on cerebral vasospasm during intracranial aneurysm surgery]. ( Han, RQ; Li, SR; Liu, W; Wang, BG; Wang, EZ; Wang, S; Zhao, JZ, 2004)
"To assess the cost-effectiveness ratio of nimodipine administration after aneurysmal subarachnoid hemorrhage (SAH) and surgery."9.09Cost-effectiveness analysis of nimodipine treatment after aneurysmal subarachnoid hemorrhage and surgery. ( Karinen, P; Koivukangas, J; Koivukangas, P; Ohinmaa, A; Ohman, J, 1999)
"The selective intra-arterial nimodipine application for the treatment of cerebral vasospasm (CVS) in patients after spontaneous subarachnoid hemorrhage (sSAH) is widely employed."8.12Radiation exposure in the intra-arterial nimodipine therapy of subarachnoid hemorrhage related cerebral vasospasm. ( Bos, D; Deuschl, C; Dörner, N; Forsting, M; Guberina, N; Jabbarli, R; Kleinschnitz, C; Li, Y; Opitz, M; Radbruch, A; Sure, U; Uslar, E; Wetter, A; Zensen, S, 2022)
"Intravenous and intra-arterial milrinone as a rescue measure for delayed cerebral ischemia (DCI) after subarachnoid hemorrhage (SAH) has been adopted by several groups, but so far, evidence for the clinical benefit is unclear and effect on brain perfusion is unknown."8.12Hemodynamic response and clinical outcome following intravenous milrinone plus norepinephrine-based hyperdynamic hypertensive therapy in patients suffering secondary cerebral ischemia after aneurysmal subarachnoid hemorrhage. ( Andereggen, L; Berberat, J; Ensner, R; Marbacher, S; Remonda, L; Steiger, HJ, 2022)
"Intra-arterial nimodipine (IAN) injections are performed in refractory delayed cerebral ischemia (DCI) related to cerebral vasospasm (CVS) after spontaneous subarachnoid hemorrhage (sSAH), but the clinical benefits are inconclusive and angiographic treatment failure is observed."8.12Analysis of Angiographic Treatment Response to Intra-Arterial Nimodipine Bolus Injection in Patients with Medically Refractory Cerebral Vasospasm After Spontaneous Subarachnoid Hemorrhage. ( Ditz, C; Küchler, J; Neumann, A; Schacht, H; Schramm, P; Tronnier, VM, 2022)
"The role of nimodipine and milrinone in the management of delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (SAH) was studied using clinical and TCD (transcranial Doppler) parameters."8.12Role of Nimodipine and Milrinone in Delayed Cerebral Ischemia. ( Chakrabarti, D; Konar, SK; Kotwal, A; Radhakrishnan, M; Ramalingaiah, AH; Shukla, D; Srinivasaiah, B; Sundaram, M, 2022)
"This study aimed to discuss the influence of nimodipine+ulinastatin on the neurological function and inflammatory reaction in patients with cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH)."8.02Influence of nimodipine combined with ulinastatin on neurological function and inflammatory reaction in patients with cerebral vasospasm after subarachnoid hemorrhage. ( Chen, M; Liu, H; Wei, X; Zhang, Q; Zou, W, 2021)
"Our findings suggest that nimodipine administration via enteral feeding tubes may be associated with vasospasm and DCI in subarachnoid hemorrhage patients secondary to reduced exposure."7.96The Impact of Nimodipine Administration through Feeding Tube on Outcomes in Patients with Aneurysmal Subarachnoid Hemorrhage. ( Abdallah, YEH; Isse, FA; Mahmoud, SH, 2020)
"Fifty-three percent of patients developed new cerebral infarction after intraarterial nimodipine and additional PTA in selected cases."7.91Complication rate of intraarterial treatment of severe cerebral vasospasm after subarachnoid hemorrhage with nimodipine and percutaneous transluminal balloon angioplasty: Worth the risk? ( Adami, D; Berkefeld, J; Konczalla, J; Pfeilschifter, W; Platz, J; Wagner, M; Weidauer, S, 2019)
"Long-term continuous intra-arterial nimodipine infusion (CIAN) is a rescue therapy option in cases of severe refractory cerebral vasospasm (CV) following acute non-traumatic subarachnoid hemorrhage (SAH)."7.88Side Effects of Long-Term Continuous Intra-arterial Nimodipine Infusion in Patients with Severe Refractory Cerebral Vasospasm after Subarachnoid Hemorrhage. ( Bele, S; Flessa, J; Graf, B; Kieninger, M; Lindenberg, N; Redel, A; Schneiker, A; Schuierer, G; Silbereisen, V; Wendl, C, 2018)
"Intra-arterial (IA) administration of nimodipine has been shown to be an effective treatment for subarachnoid hemorrhage-related cerebral vasospasm."7.85Pharmacokinetic Modeling of Intra-arterial Nimodipine Therapy for Subarachnoid Hemorrhage-Related Cerebral Vasospasm. ( Brockmann, C; Brockmann, MA; Groden, C; Hesser, J; Neumaier-Probst, E; Schubert, R; Seker, F, 2017)
"For the treatment and prevention of delayed cerebral ischemia after subarachnoid hemorrhage, the vasodilating agent nimodipine (NDP) is widely employed."7.85Effect of Intra-Arterial and Intravenous Nimodipine Therapy of Cerebral Vasospasm After Subarachnoid Hemorrhage on Cerebrovascular Reactivity and Oxygenation. ( Birkenhauer, U; Diedler, J; Ernemann, U; Hockel, K; Schuhmann, MU; Steiner, J, 2017)
" In this study, the authors examined the effects of treatment with the NO donor molsidomine with regard to decreasing the incidence of spasm-related delayed brain infarctions and improving clinical outcome in patients with SAH."7.83Molsidomine for the prevention of vasospasm-related delayed ischemic neurological deficits and delayed brain infarction and the improvement of clinical outcome after subarachnoid hemorrhage: a single-center clinical observational study. ( Brüning, R; Ehlert, A; Heindel, W; Hesselmann, V; Jacobs, AH; Manthei, G; Pluta, RM; Ringelstein, EB; Schmidt, C; Stummer, W; Wölfer, J, 2016)
"The incidence of cerebral infarction and poor outcome in patients with aneurysmal subarachnoid hemorrhage (aSAH) is reduced by oral nimodipine but acute effects of the drug may include a significant decrease in mean arterial blood pressure (MAP)."7.83Nimodipine Dose Reductions in the Treatment of Patients with Aneurysmal Subarachnoid Hemorrhage. ( Diesing, D; Sandow, N; Sarrafzadeh, A; Vajkoczy, P; Wolf, S, 2016)
"Records of children with a confirmed diagnosis of subarachnoid hemorrhage who received nimodipine between January 1, 2005 and August 31, 2013 were reviewed."7.81Nimodipine for the prevention of cerebral vasospasm after subarachnoid hemorrhage in 12 children. ( Heffren, J; McIntosh, AM; Reiter, PD, 2015)
"Nimodipine is a widely used medication for treating delayed cerebral ischemia (DCI) after subarachnoid hemorrhage."7.81Intracranial biodegradable silica-based nimodipine drug release implant for treating vasospasm in subarachnoid hemorrhage in an experimental healthy pig and dog model. ( Ahtola-Sätilä, T; Forsback, AP; Frantzén, J; Koskimäki, J; Laakso, A; Saloranta, L; Simola, O; Tarkia, M, 2015)
"In thirty patients with aneurysmal subarachnoid hemorrhage and refractory vasospasm continuous infusion of nimodipine was started on the neurosurgical intensive care unit."7.80Continuous selective intra-arterial application of nimodipine in refractory cerebral vasospasm due to aneurysmal subarachnoid hemorrhage. ( Jedlicka, S; Lumenta, CB; Merker, P; Ott, S; Peter, M; Pudenz, C; Schürer, L; Wolf, S, 2014)
"We sought to explore whether topical administration of nimodipine improves the abnormal cerebral perfusion following subarachnoid hemorrhage (SAH) in pigs."7.79Effects of topical administration of nimodipine on cerebral blood flow following subarachnoid hemorrhage in pigs. ( Jia, F; Jiang, JY; Wang, F; Yin, YH, 2013)
"Nimodipine improved outcome in patients with subarachnoid hemorrhage (SAH) although hypotension limited the dose that could be administered systemically."7.78Cisternal sustained release dihydropyridines for subarachnoid hemorrhage. ( Ai, J; Cook, DJ; Kan, S; Kasuya, H; Macdonald, RL, 2012)
"To investigate the effect of locally applied nimodipine prolonged-release microparticles on angiographic vasospasm and secondary brain injury after experimental subarachnoid hemorrhage (SAH)."7.78Local delivery of nimodipine by prolonged-release microparticles-feasibility, effectiveness and dose-finding in experimental subarachnoid hemorrhage. ( Bege, N; Beseoglu, K; Eicker, S; Etminan, N; Frauenknecht, K; Hänggi, D; Heiroth, HJ; Kamp, MA; Kissel, T; Macht, S; Perrin, J; Sommer, C; Steiger, HJ, 2012)
"the aim of this study was to assess and to compare the ability of intrathecal flunarizine and nimodipine to prevent vasospasm in a rabbit model of subarachnoid hemorrhage (SAH)."7.77Comparison of intrathecal flunarizine and nimodipine treatments in cerebral vasospasm after experimental subarachnoid hemorrhage in rabbits. ( Civelek, E; Gonul, E; Izci, Y; Kircelli, A; Onal, MB; Secer, HI; Solmaz, I; Temiz, C, 2011)
"This study evaluated the efficacy of intra-arterial nimodipine infusion for symptomatic vasospasm in patients with aneurysmal subarachnoid hemorrhage (aSAH)."7.77Intra-arterial nimodipine infusion for cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. ( Cho, WS; Hang, MH; Jung, C; Kang, HS; Kim, JE; Know, BJ; Kwon, OK; Oh, CW; Son, YJ, 2011)
"We investigated the effect of ebselen relative to nimodipine in an animal model of subarachnoid hemorrhage."7.76Effects of ebselen versus nimodipine on cerebral vasospasm subsequent to experimental subarachnoid hemorrhage in rats. ( Acikgoz, B; Acikgoz, S; Ankarali, H; Bahadir, B; Bektas, S; Gul, S; Hanci, V; Kalayci, M; Ugurbas, E, 2010)
"To explore the dose-response effects of topical administration of nimodipine on cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH) in rabbits."7.75Effects of dose-response of topical administration of nimodipine on cerebral vasospasm after subarachnoid hemorrhage in rabbits. ( Jiang, JY; Luo, QZ; Pan, YH; Wang, F; Wang, Y; Yin, YH, 2009)
"Sixty-five male Wistar rats were randomized into 4 groups: the control sham-operated group, the control subarachnoid hemorrhage-only group, and the treatment groups receiving 5 or 10 microL/hour of intracisternal nimodipine continuously for 5 days via subcutaneously implanted Alzet osmotic pumps (Durect Corp."7.75Dose-related efficacy of a continuous intracisternal nimodipine treatment on cerebral vasospasm in the rat double subarachnoid hemorrhage model. ( Beseoglu, K; Eicker, S; Hänggi, D; Nawatny, J; Perrin, J; Rapp, M; Sommer, C; Steiger, HJ; Turowski, B, 2009)
"Our aim in this study was to investigate the efficacy of intravenous administration of cilostazol and compare these effects with intravenous usage of nimodipine in subarachnoid hemorrhage model."7.75The effects of intravenous cilostazol and nimodipine on cerebral vasospasm after subarachnoid hemorrhage in an experimental rabbit model. ( Bilginer, B; Narin, F; Onal, MB; Ozgen, T; Soylemezoglu, F; Ziyal, IM, 2009)
"Cerebral vasospasm is a common complication of subarachnoid hemorrhage."6.72Side effects of continuous intra-arterial infusion of nimodipine for management of resistant cerebral vasospasm in subarachnoid hemorrhage patients: A systematic review. ( Bilotta, F; Sarria-Santamera, A; Viderman, D, 2021)
"Severe refractory cerebral vasospasm (CV) is a major cause of disability and death in patients with aneurysmal subarachnoid hemorrhage (SAH)."5.72Continuous intra-arterial nimodipine infusion as rescue treatment of severe refractory cerebral vasospasm after aneurysmal subarachnoid hemorrhage. ( Anthofer, J; Bele, S; Bruendl, E; Kieninger, M; Schebesch, KM; Schmidt, NO; Wendl, C; Zeman, F, 2022)
"Cerebral vasospasm (CV) and delayed cerebral ischemia (DCI) are major factors that limit good outcome in patients with spontaneous subarachnoid hemorrhage (SAH)."5.51The evolution of invasive cerebral vasospasm treatment in patients with spontaneous subarachnoid hemorrhage and delayed cerebral ischemia-continuous selective intracarotid nimodipine therapy in awake patients without sedation. ( Brand, C; Braun, M; Kapapa, T; König, R; Özpeynirci, Y; Paľa, A; Pedro, MT; Schmitz, B; Schneider, M; Wirtz, CR, 2019)
"Cerebral vasospasm following subarachnoid hemorrhage (SAH) is the most important complication that effects the mortality and morbidity of patients with intracranial aneurysm."5.46Comparison of the Effects and Mechanism of the Curcumin with Different Drugs in Experimental Vasospasm After Subarachnoid Hemorrhage. ( Aydin, HE; Baycu, C; Bektur, NE; Kilic, FS; Oner, S; Ozbek, Z, 2017)
" Key to the effective administration of continuous intra-arterial nimodipine is multimodal neuromonitoring and the individual adaptation of dosage and time of infusion for each patient."5.42Continuous intra-arterial nimodipine infusion in patients with severe refractory cerebral vasospasm after aneurysmal subarachnoid hemorrhage: a feasibility study and outcome results. ( Bele, S; Brawanski, A; Bründl, E; Hochreiter, A; Kieninger, M; Proescholdt, MA; Schebesch, KM; Scheitzach, J; Schneiker, A; Schödel, P; Schuierer, G; Wendl, C, 2015)
"These results are consistent with a beneficial effect of locally delivered nimodipine (EG-1962) on SD after aSAH in more severely injured patients who are at risk of delayed cerebral ischemia related to SD."5.41Effect of Locally Delivered Nimodipine Microparticles on Spreading Depolarization in Aneurysmal Subarachnoid Hemorrhage. ( Alchbli, A; Carlson, AP; Hänggi, D; Macdonald, RL; Shuttleworth, CW, 2021)
"Nimodipine treatment in cerebral vasospasm is useful."5.37Comparison of nimodipine delivery routes in cerebral vasospasm after subarachnoid hemorrhage: an experimental study in rabbits. ( Bilginer, B; Civelek, E; Isikay, I; Kircelli, A; Narin, F; Onal, MB; Solmaz, I; Ugurel, S; Yakupoglu, H, 2011)
"Nimodipine is an effect-proven agent in CVS, but dotarizine may take place of it."5.37Comparison of intrathecal dotarizine and nimodipine treatments in cerebral vasospasm after subarachnoid hemorrhage: an experimental study in rabbits. ( Civelek, E; Erdogan, E; Gonul, E; Izci, Y; Kircelli, A; Onal, MB; Solmaz, I; Tehli, O, 2011)
"Nimodipine is a potent drug for vessel relaxation, but side effects may preclude a sufficient dose."5.37Continuous local intra-arterial nimodipine administration in severe symptomatic vasospasm after subarachnoid hemorrhage. ( Coburger, J; Henkes, H; Hopf, N; Musahl, C; Vajda, Z, 2011)
"Cerebral vasospasm complicating aneurysmal subarachnoid hemorrhage is a well-known medical entity."5.37Resistant vasospasm in subarachnoid hemorrhage treated with continuous intraarterial nimodipine infusion. ( Barth, H; Doukas, A; Jansen, O; Maslehaty, H; Mehdorn, HM; Petridis, AK, 2011)
"Brain hemodynamics in cerebral malaria (CM) is poorly understood, with apparently conflicting data showing microcirculatory hypoperfusion and normal or even increased blood flow in large arteries."5.36Murine cerebral malaria is associated with a vasospasm-like microcirculatory dysfunction, and survival upon rescue treatment is markedly increased by nimodipine. ( Cabrales, P; Carvalho, LJ; Frangos, JA; Meays, D; Zanini, GM, 2010)
"One of the challenges in bringing new therapeutic agents (since nimodipine) in for the treatment of cerebral ischemia associated with aneurysmal subarachnoid hemorrhage (aSAH) is the incongruence in therapeutic benefit observed between phase II and subsequent phase III clinical trials."5.22Lessons Learned from Phase II and Phase III Trials Investigating Therapeutic Agents for Cerebral Ischemia Associated with Aneurysmal Subarachnoid Hemorrhage. ( Broderick, JP; Cassarly, CN; Huang, W; Ishfaq, MF; Lobanova, I; Macdonald, RL; Martin, RH; Qureshi, AI; Suarez, JI, 2022)
"Nimodipine and cilostazol are likely the most effective treatments in preventing morbidity and mortality in patients with aneurysmal subarachnoid hemorrhage."5.22Prophylactic Therapies for Morbidity and Mortality After Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Network Meta-Analysis of Randomized Trials. ( Ahmadvand, S; Amin-Hanjani, S; Dayyani, M; Grotta, JC; Guyatt, GH; Sadeghirad, B; Wang, Y; Zabihyan, S, 2022)
"Our objective was to compare the effectiveness of intravenous and enteral nimodipine in preventing poor outcome from delayed cerebral ischemia in patients with subarachnoid hemorrhage."5.22A Comparison Between Enteral and Intravenous Nimodipine in Subarachnoid Hemorrhage: A Systematic Review and Network Meta-Analysis. ( Boscolo, A; Cacco, N; Carere, A; Correale, C; De Cassai, A; Diana, P; Disarò, L; Geraldini, F; Munari, M; Navalesi, P; Zampirollo, S, 2022)
"Fasudil is believed to be at least equally effective as nimodipine for the prevention of cerebral vasospasm and subsequent ischemic injury in patients undergoing surgery for subarachnoid hemorrhage (SAH)."5.15Efficacy and safety of fasudil in patients with subarachnoid hemorrhage: final results of a randomized trial of fasudil versus nimodipine. ( Guo, J; Mao, Y; Ren, Z; Wang, R; Wang, S; Xu, B; Zhang, X; Zhang, Y; Zhao, J; Zhao, K; Zhou, D; Zhou, L, 2011)
"The calcium antagonist nimodipine has been shown to reduce the incidence of ischemic complications following aneurysmal subarachnoid hemorrhage (SAH)."5.14Nimodipine in aneurysmal subarachnoid hemorrhage: a randomized study of intravenous or peroral administration. ( Cronqvist, M; Kronvall, E; Nilsson, OG; Romner, B; Säveland, H; Undrén, P, 2009)
"The efficacy of intra-arterial administration of nimodipine (IAN) in patients with severe vasospasm after aneurysmal subarachnoid hemorrhage (SAH) remains unproved."5.13Intra-arterial nimodipine for severe cerebral vasospasm after aneurysmal subarachnoid hemorrhage: influence on clinical course and cerebral perfusion. ( Beseoglu, K; Hänggi, D; Steiger, HJ; Turowski, B; Yong, M, 2008)
"The prophylactic use of nimodipine in patients with aneurysmal subarachnoid hemorrhage reduces the risk of ischemic brain damage."5.12Intravenous magnesium versus nimodipine in the treatment of patients with aneurysmal subarachnoid hemorrhage: a randomized study. ( Briegel, J; Kunz, M; Prueckner, S; Schmid-Elsaesser, R; Steiger, HJ; Zausinger, S, 2006)
" This randomized open trial with nimodipine as the control included 72 patients who underwent subarachnoid hemorrhage surgery for ruptured cerebral aneurysm of Hunt and Hess grades I to IV."5.12Effect of fasudil hydrochloride, a protein kinase inhibitor, on cerebral vasospasm and delayed cerebral ischemic symptoms after aneurysmal subarachnoid hemorrhage. ( Guo, J; Ren, Z; Wang, R; Wang, S; Xu, B; Zhao, J; Zhou, D; Zhou, L, 2006)
"Eleven patients with primary thunderclap headache (TCH) were treated with oral nimodipine 30 to 60 mg every 4 hours or IV nimodipine 0."5.11Nimodipine for treatment of primary thunderclap headache. ( Fuh, JL; Liao, YC; Lirng, JF; Lu, SR; Wang, SJ, 2004)
"Thirty consecutive patients under-going intracranial aneurysmal surgery were prospectively randomized into two groups: Isoflurane (group A, n = 15) and nimodipine (group B, n = 15)."5.11[The effect of intraoperative continuous nimodipine infusion on cerebral vasospasm during intracranial aneurysm surgery]. ( Han, RQ; Li, SR; Liu, W; Wang, BG; Wang, EZ; Wang, S; Zhao, JZ, 2004)
"To assess the cost-effectiveness ratio of nimodipine administration after aneurysmal subarachnoid hemorrhage (SAH) and surgery."5.09Cost-effectiveness analysis of nimodipine treatment after aneurysmal subarachnoid hemorrhage and surgery. ( Karinen, P; Koivukangas, J; Koivukangas, P; Ohinmaa, A; Ohman, J, 1999)
" Clinical trials in subarachnoid hemorrhage have led to approval of nimodipine for oral and intravenous use, but other drugs, such as clazosentan, hydroxymethylglutaryl CoA reductase inhibitors (statins) and magnesium, have not shown consistent clinical efficacy."4.88Intracranial drug delivery for subarachnoid hemorrhage. ( Leung, M; Macdonald, RL; Tice, T, 2012)
"Nimodipine (Nimotop), HMG Co-A reductase inhibitor (statins) and enoxaparin (Lovenox) were the only drugs with level-1 evidence available for the treatment of vasospasm from aneurysmal subarachnoid hemorrhage as defined by the US Preventative Services Task Force."4.85Evidence-based pharmacotherapy for cerebral vasospasm. ( Boulos, AS; Deshaies, EM; Drazin, D; Popp, AJ, 2009)
"A total of 40 rabbits were used to make subarachnoid hemorrhage model and were divided into three groups - a control group, nimodipine group, and tadalafil group."4.31Vasodilatory effects of tadalafil in an animal model of cerebral vasospasm: Comparative analysis with oral nimodipine. ( Byoun, HS; Il Won, Y; Lim, J; Park, B; Park, KH; Youm, JY, 2023)
"The selective intra-arterial nimodipine application for the treatment of cerebral vasospasm (CVS) in patients after spontaneous subarachnoid hemorrhage (sSAH) is widely employed."4.12Radiation exposure in the intra-arterial nimodipine therapy of subarachnoid hemorrhage related cerebral vasospasm. ( Bos, D; Deuschl, C; Dörner, N; Forsting, M; Guberina, N; Jabbarli, R; Kleinschnitz, C; Li, Y; Opitz, M; Radbruch, A; Sure, U; Uslar, E; Wetter, A; Zensen, S, 2022)
"Intravenous and intra-arterial milrinone as a rescue measure for delayed cerebral ischemia (DCI) after subarachnoid hemorrhage (SAH) has been adopted by several groups, but so far, evidence for the clinical benefit is unclear and effect on brain perfusion is unknown."4.12Hemodynamic response and clinical outcome following intravenous milrinone plus norepinephrine-based hyperdynamic hypertensive therapy in patients suffering secondary cerebral ischemia after aneurysmal subarachnoid hemorrhage. ( Andereggen, L; Berberat, J; Ensner, R; Marbacher, S; Remonda, L; Steiger, HJ, 2022)
"Intra-arterial nimodipine (IAN) injections are performed in refractory delayed cerebral ischemia (DCI) related to cerebral vasospasm (CVS) after spontaneous subarachnoid hemorrhage (sSAH), but the clinical benefits are inconclusive and angiographic treatment failure is observed."4.12Analysis of Angiographic Treatment Response to Intra-Arterial Nimodipine Bolus Injection in Patients with Medically Refractory Cerebral Vasospasm After Spontaneous Subarachnoid Hemorrhage. ( Ditz, C; Küchler, J; Neumann, A; Schacht, H; Schramm, P; Tronnier, VM, 2022)
"The role of nimodipine and milrinone in the management of delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (SAH) was studied using clinical and TCD (transcranial Doppler) parameters."4.12Role of Nimodipine and Milrinone in Delayed Cerebral Ischemia. ( Chakrabarti, D; Konar, SK; Kotwal, A; Radhakrishnan, M; Ramalingaiah, AH; Shukla, D; Srinivasaiah, B; Sundaram, M, 2022)
"This study aimed to discuss the influence of nimodipine+ulinastatin on the neurological function and inflammatory reaction in patients with cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH)."4.02Influence of nimodipine combined with ulinastatin on neurological function and inflammatory reaction in patients with cerebral vasospasm after subarachnoid hemorrhage. ( Chen, M; Liu, H; Wei, X; Zhang, Q; Zou, W, 2021)
"Our findings suggest that nimodipine administration via enteral feeding tubes may be associated with vasospasm and DCI in subarachnoid hemorrhage patients secondary to reduced exposure."3.96The Impact of Nimodipine Administration through Feeding Tube on Outcomes in Patients with Aneurysmal Subarachnoid Hemorrhage. ( Abdallah, YEH; Isse, FA; Mahmoud, SH, 2020)
"Fifty-three percent of patients developed new cerebral infarction after intraarterial nimodipine and additional PTA in selected cases."3.91Complication rate of intraarterial treatment of severe cerebral vasospasm after subarachnoid hemorrhage with nimodipine and percutaneous transluminal balloon angioplasty: Worth the risk? ( Adami, D; Berkefeld, J; Konczalla, J; Pfeilschifter, W; Platz, J; Wagner, M; Weidauer, S, 2019)
"Long-term continuous intra-arterial nimodipine infusion (CIAN) is a rescue therapy option in cases of severe refractory cerebral vasospasm (CV) following acute non-traumatic subarachnoid hemorrhage (SAH)."3.88Side Effects of Long-Term Continuous Intra-arterial Nimodipine Infusion in Patients with Severe Refractory Cerebral Vasospasm after Subarachnoid Hemorrhage. ( Bele, S; Flessa, J; Graf, B; Kieninger, M; Lindenberg, N; Redel, A; Schneiker, A; Schuierer, G; Silbereisen, V; Wendl, C, 2018)
"Using PubMed and Google Scholar, we performed a search of the English language literature with several combinations of the keywords "intra-arterial", "calcium channel blockers", "reversible cerebral vasoconstriction syndrome", "RCVS", "nimodipine", "verapamil", "milrinone", and "nicardipine" to identify studies in which RCVS was treated with IA calcium channel blockers."3.88Chemical angioplasty for medically refractory reversible cerebral vasoconstriction syndrome ( Al-Mufti, F; Alchaki, A; Dodson, V; El-Ghanem, M; Gupta, G; Hidalgo, A; Nuoman, R; Roychowdhury, S; Sutherland, A; Thabet, A; Wajswol, E, 2018)
"Oral nimodipine is an established prophylactic agent for cerebral vasospasm after subarachnoid hemorrhage (SAH)."3.85Systemic and Cerebral Concentration of Nimodipine During Established and Experimental Vasospasm Treatment. ( Albanna, W; Clusmann, H; Conzen, C; Höllig, A; Müller, M; Reinsch, M; Schneider, T; Schubert, GA; Weiss, M; Wiesmann, M, 2017)
"Intra-arterial (IA) administration of nimodipine has been shown to be an effective treatment for subarachnoid hemorrhage-related cerebral vasospasm."3.85Pharmacokinetic Modeling of Intra-arterial Nimodipine Therapy for Subarachnoid Hemorrhage-Related Cerebral Vasospasm. ( Brockmann, C; Brockmann, MA; Groden, C; Hesser, J; Neumaier-Probst, E; Schubert, R; Seker, F, 2017)
"For the treatment and prevention of delayed cerebral ischemia after subarachnoid hemorrhage, the vasodilating agent nimodipine (NDP) is widely employed."3.85Effect of Intra-Arterial and Intravenous Nimodipine Therapy of Cerebral Vasospasm After Subarachnoid Hemorrhage on Cerebrovascular Reactivity and Oxygenation. ( Birkenhauer, U; Diedler, J; Ernemann, U; Hockel, K; Schuhmann, MU; Steiner, J, 2017)
" In this study, the authors examined the effects of treatment with the NO donor molsidomine with regard to decreasing the incidence of spasm-related delayed brain infarctions and improving clinical outcome in patients with SAH."3.83Molsidomine for the prevention of vasospasm-related delayed ischemic neurological deficits and delayed brain infarction and the improvement of clinical outcome after subarachnoid hemorrhage: a single-center clinical observational study. ( Brüning, R; Ehlert, A; Heindel, W; Hesselmann, V; Jacobs, AH; Manthei, G; Pluta, RM; Ringelstein, EB; Schmidt, C; Stummer, W; Wölfer, J, 2016)
"The incidence of cerebral infarction and poor outcome in patients with aneurysmal subarachnoid hemorrhage (aSAH) is reduced by oral nimodipine but acute effects of the drug may include a significant decrease in mean arterial blood pressure (MAP)."3.83Nimodipine Dose Reductions in the Treatment of Patients with Aneurysmal Subarachnoid Hemorrhage. ( Diesing, D; Sandow, N; Sarrafzadeh, A; Vajkoczy, P; Wolf, S, 2016)
"Records of children with a confirmed diagnosis of subarachnoid hemorrhage who received nimodipine between January 1, 2005 and August 31, 2013 were reviewed."3.81Nimodipine for the prevention of cerebral vasospasm after subarachnoid hemorrhage in 12 children. ( Heffren, J; McIntosh, AM; Reiter, PD, 2015)
"Nimodipine is a widely used medication for treating delayed cerebral ischemia (DCI) after subarachnoid hemorrhage."3.81Intracranial biodegradable silica-based nimodipine drug release implant for treating vasospasm in subarachnoid hemorrhage in an experimental healthy pig and dog model. ( Ahtola-Sätilä, T; Forsback, AP; Frantzén, J; Koskimäki, J; Laakso, A; Saloranta, L; Simola, O; Tarkia, M, 2015)
"In thirty patients with aneurysmal subarachnoid hemorrhage and refractory vasospasm continuous infusion of nimodipine was started on the neurosurgical intensive care unit."3.80Continuous selective intra-arterial application of nimodipine in refractory cerebral vasospasm due to aneurysmal subarachnoid hemorrhage. ( Jedlicka, S; Lumenta, CB; Merker, P; Ott, S; Peter, M; Pudenz, C; Schürer, L; Wolf, S, 2014)
"We sought to explore whether topical administration of nimodipine improves the abnormal cerebral perfusion following subarachnoid hemorrhage (SAH) in pigs."3.79Effects of topical administration of nimodipine on cerebral blood flow following subarachnoid hemorrhage in pigs. ( Jia, F; Jiang, JY; Wang, F; Yin, YH, 2013)
"Nimodipine improved outcome in patients with subarachnoid hemorrhage (SAH) although hypotension limited the dose that could be administered systemically."3.78Cisternal sustained release dihydropyridines for subarachnoid hemorrhage. ( Ai, J; Cook, DJ; Kan, S; Kasuya, H; Macdonald, RL, 2012)
"To investigate the effect of locally applied nimodipine prolonged-release microparticles on angiographic vasospasm and secondary brain injury after experimental subarachnoid hemorrhage (SAH)."3.78Local delivery of nimodipine by prolonged-release microparticles-feasibility, effectiveness and dose-finding in experimental subarachnoid hemorrhage. ( Bege, N; Beseoglu, K; Eicker, S; Etminan, N; Frauenknecht, K; Hänggi, D; Heiroth, HJ; Kamp, MA; Kissel, T; Macht, S; Perrin, J; Sommer, C; Steiger, HJ, 2012)
"the aim of this study was to assess and to compare the ability of intrathecal flunarizine and nimodipine to prevent vasospasm in a rabbit model of subarachnoid hemorrhage (SAH)."3.77Comparison of intrathecal flunarizine and nimodipine treatments in cerebral vasospasm after experimental subarachnoid hemorrhage in rabbits. ( Civelek, E; Gonul, E; Izci, Y; Kircelli, A; Onal, MB; Secer, HI; Solmaz, I; Temiz, C, 2011)
"the aim of this study was to assess and to compare the ability of intrathecal nicergoline and nimodipine in prevention of cerebral vasospasm in a rabbit model of subarachnoid hemorrhage (SAH)."3.77The effects of intrathecal nicergoline and nimodipine in cerebral vasospasm: an experimental study in rabbits. ( Civelek, E; Erdogan, E; Gonul, E; Kircelli, A; Onal, MB; Ongoru, O; Solmaz, I; Ugurel, S, 2011)
"This study evaluated the efficacy of intra-arterial nimodipine infusion for symptomatic vasospasm in patients with aneurysmal subarachnoid hemorrhage (aSAH)."3.77Intra-arterial nimodipine infusion for cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. ( Cho, WS; Hang, MH; Jung, C; Kang, HS; Kim, JE; Know, BJ; Kwon, OK; Oh, CW; Son, YJ, 2011)
"For endovascular treatment of vasospasm after aneurysmal subarachnoid hemorrhage (aSAH), an intraarterial treatment course with the calcium channel antagonist nimodipine infused for 30 min is proposed."3.76Continuous selective intraarterial infusion of nimodipine for therapy of refractory cerebral vasospasm. ( Landscheidt, JF; Lumenta, CB; Martin, H; Rodiek, SO; Schürer, L; Wolf, S, 2010)
"We investigated the effect of ebselen relative to nimodipine in an animal model of subarachnoid hemorrhage."3.76Effects of ebselen versus nimodipine on cerebral vasospasm subsequent to experimental subarachnoid hemorrhage in rats. ( Acikgoz, B; Acikgoz, S; Ankarali, H; Bahadir, B; Bektas, S; Gul, S; Hanci, V; Kalayci, M; Ugurbas, E, 2010)
"To explore the dose-response effects of topical administration of nimodipine on cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH) in rabbits."3.75Effects of dose-response of topical administration of nimodipine on cerebral vasospasm after subarachnoid hemorrhage in rabbits. ( Jiang, JY; Luo, QZ; Pan, YH; Wang, F; Wang, Y; Yin, YH, 2009)
"Sixty-five male Wistar rats were randomized into 4 groups: the control sham-operated group, the control subarachnoid hemorrhage-only group, and the treatment groups receiving 5 or 10 microL/hour of intracisternal nimodipine continuously for 5 days via subcutaneously implanted Alzet osmotic pumps (Durect Corp."3.75Dose-related efficacy of a continuous intracisternal nimodipine treatment on cerebral vasospasm in the rat double subarachnoid hemorrhage model. ( Beseoglu, K; Eicker, S; Hänggi, D; Nawatny, J; Perrin, J; Rapp, M; Sommer, C; Steiger, HJ; Turowski, B, 2009)
"Our aim in this study was to investigate the efficacy of intravenous administration of cilostazol and compare these effects with intravenous usage of nimodipine in subarachnoid hemorrhage model."3.75The effects of intravenous cilostazol and nimodipine on cerebral vasospasm after subarachnoid hemorrhage in an experimental rabbit model. ( Bilginer, B; Narin, F; Onal, MB; Ozgen, T; Soylemezoglu, F; Ziyal, IM, 2009)
"Nimodipine is a therapy that reduces morbidity and mortality in patients with subarachnoid hemorrhage (SAH), though the mechanisms by which it does so are not well understood."3.73Dynamic CT perfusion imaging in subarachnoid hemorrhage-related vasospasm. ( Chen, FX; Eastwood, JD; Laslo, AM; Lee, TY, 2006)
"The efficacy of nimodipine was examined in a murine model of subarachnoid hemorrhage (SAH)."3.73Dissociation between vasospasm and functional improvement in a murine model of subarachnoid hemorrhage. ( Borel, CO; Laskowitz, DT; Lombard, FW; Mesis, RG; Vitek, MP; Wang, H; Warner, DS; Yates, R, 2006)
" Cerebral vasospasm (CV) after aneurysmal subarachnoid hemorrhage (aSAH) is still a problem."3.11Clinical Outcome in Cerebral Vasospasm Patients Treated with and without Intra-Arterial Nimodipine Infusion. ( Nimmannitya, P; Noiphithak, R; Punyarat, P; Tantongtip, D; Yindeedej, V, 2022)
"Cerebral vasospasm is one of the frequent complications that can occur following subarachnoid hemorrhage (SAH)."3.01Cerebral Vasospasm: Practical Review of Diagnosis and Management. ( Artico, M; Berger, JM; Caramuta, M; Longhitano, Y; Maconi, A; Piccolella, F; Romenskaya, T; Saviano, A; Savioli, G; Taurone, S; Zanza, C, 2023)
" However, 4-hourly dosing is a practical limitation and verapamil has been proposed as an alternative."3.01Verapamil in the treatment of reversible cerebral vasoconstriction syndrome: A systematic review. ( Bacchi, S; Bagster, M; Collins, L; Goh, R; Gupta, A; Kleinig, O; Kleinig, T; Kovoor, J; Lam, L; Proudman, W; Schultz, D; Zhang, R, 2023)
"Poor outcomes in Subarachnoid Hemorrhage (SAH) are in part due to a unique form of secondary neurological injury known as Delayed Cerebral Ischemia (DCI)."3.01Cortical Spreading Depolarization and Delayed Cerebral Ischemia; Rethinking Secondary Neurological Injury in Subarachnoid Hemorrhage. ( Bischof, H; Diedrich, D; Gomez, F; Laudanski, K; Mehra, A, 2023)
"Aneurysmal subarachnoid hemorrhage (aSAH) is a severe subtype of stroke occurring at a relatively young age with a significant socioeconomic impact."2.82Therapeutic Approaches for Cerebrovascular Dysfunction After Aneurysmal Subarachnoid Hemorrhage: An Update and Future Perspectives. ( Grasso, G; Torregrossa, F, 2022)
"Aneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening condition associated with the development of early brain injury (EBI) and delayed cerebral ischemia (DCI)."2.72Non-steroidal anti-inflammatory drugs in the pathophysiology of vasospasms and delayed cerebral ischemia following subarachnoid hemorrhage: a critical review. ( Jancalek, R; Joukal, M; Mackerle, Z; Solar, P, 2021)
"Cerebral vasospasm is a common complication of subarachnoid hemorrhage."2.72Side effects of continuous intra-arterial infusion of nimodipine for management of resistant cerebral vasospasm in subarachnoid hemorrhage patients: A systematic review. ( Bilotta, F; Sarria-Santamera, A; Viderman, D, 2021)
"Nimodipine has a good effect on releasing spasm and diminishing the cerebral blood flow velocity."2.70Mechanism and treatment principle for cerebral vessel spasm caused by concussion. ( Guo, X; Wang, D; Xiao, X; Xue, G, 2002)
"Aneurysmal subarachnoid hemorrhage (aSAH) represents 3% of all strokes in the US."2.58Investigational drugs for vasospasm after subarachnoid hemorrhage. ( Freeman, WD; Pizzi, MA; Tallarico, RT, 2018)
"Early treatment of ruptured aneurysms is advocated; delayed intervention complicates the treatment strategy leading to significant vasospasm and poor prognosis."2.58Coadjuvant Treatment of Vasospasm in Ruptured Unsecured Cerebral Aneurysms with Aggressive Angioplasty, Intra-Arterial Nimodipine, and Aneurysm Embolization. ( Chen, CC; Chen, CT; Hsieh, PC; Yi-Chou Wang, A, 2018)
"Bath-related headache is a rare form of thunderclap headache."2.58Bath-Related Headache. ( Kumpinsky, A; Nahas, SJ, 2018)
"Large-vessel cerebral vasospasm has been challenged as the sole causal mechanism; new hypotheses now focus on the early brain injury, microcirculatory dysfunction, impaired autoregulation, and spreading depolarization."2.53Management of delayed cerebral ischemia after subarachnoid hemorrhage. ( Francoeur, CL; Mayer, SA, 2016)
"Outcome of patients with aneurysmal subarachnoid hemorrhage (SAH) has improved over the last decades."2.49SAHIT Investigators--on the outcome of some subarachnoid hemorrhage clinical trials. ( Cusimano, MD; Etminan, N; Hanggi, D; Hasan, D; Ilodigwe, D; Jaja, B; Lantigua, H; Le Roux, P; Lo, B; Louffat-Olivares, A; Macdonald, RL; Mayer, S; Molyneux, A; Quinn, A; Schenk, T; Schweizer, TA; Singh, J; Spears, J; Todd, M; Torner, J; Vergouwen, MD; Wong, GK, 2013)
"This process, known as cerebral vasospasm, is the most common cause of DCI after SAH."2.48Management of delayed cerebral ischemia after subarachnoid hemorrhage. ( Koenig, MA, 2012)
"Aneurysmal subarachnoid hemorrhage (SAH) accounts for a significant percentage of morbidity and mortality among patients admitted to neurosurgical centers throughout the world."2.46Role of intraarterial therapy for cerebral vasospasm secondary to aneurysmal subarachnoid hemorrhage. ( Cook, AM; Ramsey, CN; Weant, KA, 2010)
"Resolution of ongoing cerebral vasospasm can be achieved by either dilating constricted vessels or optimizing hemodynamics."2.43Detecting and treating microvascular ischemia after subarachnoid hemorrhage. ( Sakowitz, OW; Unterberg, AW, 2006)
"Among patients with symptomatic cerebral vasospasm around 1/3 fully recover in 1/3 of cases persistent neurological deficit remains and 1/3 of the patients die."2.41[Cerebral vasospasm after subarachnoid hemorrhage. Current possibilities of prevention and treatment]. ( Danilewicz, B; Stachura, K, 2002)
"Severe refractory cerebral vasospasm (CV) is a major cause of disability and death in patients with aneurysmal subarachnoid hemorrhage (SAH)."1.72Continuous intra-arterial nimodipine infusion as rescue treatment of severe refractory cerebral vasospasm after aneurysmal subarachnoid hemorrhage. ( Anthofer, J; Bele, S; Bruendl, E; Kieninger, M; Schebesch, KM; Schmidt, NO; Wendl, C; Zeman, F, 2022)
"Delayed cerebral ischemia (DCI) contributes to poor outcomes after subarachnoid hemorrhage (SAH)."1.72Large practice variations in diagnosis and treatment of delayed cerebral ischemia after subarachnoid hemorrhage. ( Coert, BA; Coutinho, JM; Horn, J; Post, R; Tjerkstra, MA; van den Berg, R; Vandertop, WP; Verbaan, D, 2022)
"Patients with refractory cerebral vasospasm treated with intra-arterial nimodipine during 2009-2020 at Sahlgrenska University Hospital were retrospectively reviewed."1.72Intra-arterial nimodipine for severe cerebral vasospasm after aneurysmal subarachnoid haemorrhage - neurological and radiological outcome. ( Nilsson, D; Rentzos, A; Samuelsson, J; Sunila, M, 2022)
" Dose-response curves for the 5-HT-induced contraction (from 0."1.62The combination of dantrolene and nimodipine effectively reduces 5-HT-induced vasospasms in diabetic rats. ( Crespo, MJ; García, L; Morales, M; Román, M, 2021)
"After spontaneous subarachnoid hemorrhage (sSAH), cerebral vasospasm (CVS) is a common complication, potentially resulting in infarction mainly responsible for a poor outcome."1.56Transluminal balloon angioplasty for cerebral vasospasm after spontaneous subarachnoid hemorrhage: A single-center experience. ( Boppel, T; Ditz, C; Küchler, J; Leppert, J; Neumann, A; Schacht, H; Schramm, P, 2020)
" In cases of spontaneous subarachnoid hemorrhage (sSAH) and symptomatic cerebral vasospasm (sCVS), multiple intra-arterial treatments (IATs) can be potentially useful for the functional outcome, even if the prognosis is initially poor."1.56Symptomatic Cerebral Vasospasm after Spontaneous Subarachnoid Hemorrhage: Comparison of Single and Multiple Intra-arterial Treatment with Respect to the Functional Outcome. ( Aulmann, L; Ditz, C; Küchler, JN; Neumann, A; Schacht, H; Schramm, P; Tronnier, VM, 2020)
"Background and Purpose- Delayed cerebral infarction (DCI) is an important cause of morbidity and mortality in patients with aneurysmal subarachnoid hemorrhage (aSAH)."1.56Impact of Stereotactic Ventriculocisternostomy on Delayed Cerebral Infarction and Outcome After Subarachnoid Hemorrhage. ( Bardutzky, J; Beck, J; Buttler, J; Coenen, VA; Csok, I; Egger, K; Grauvogel, J; Niesen, WD; Reinacher, PC; Roelz, R; Rohr, E; Sajonz, B; Schaefer, JH; Scheiwe, C; Shah, MJ; Steiert, C, 2020)
"This study aims to investigate the effect of nimodipine combined with betahistine on the levels of CRP and other inflammatory cytokines, as well as vascular endothelial function in patients with hypertensive cerebral vasospasm."1.56Effects of nimodipine combined with betahistine on CRP and other inflammatory cytokines and vascular endothelial function in patients with hypertensive cerebral vasospasm. ( Liu, X; Luo, X; Sheng, P; Wang, Y; Xiao, P; Zeng, K; Zhao, N, 2020)
"IaN for aSAH-related cerebral vasospasm did not improve rScO2 but was associated with significant systemic hemodynamic effects, including a decrease in MBP and TPRI."1.56Effect of Intra-arterial Nimodipine on Cerebral Oxygen Saturation and Systemic Hemodynamic Indices in Patients With Cerebral Vasospasm: A Prospective Cohort Study. ( Palaniswamy, SR; Ramalingaiah, AH; Sriganesh, K; Venkataramaiah, S, 2020)
"Cerebral vasospasm (CV) and delayed cerebral ischemia (DCI) are major factors that limit good outcome in patients with spontaneous subarachnoid hemorrhage (SAH)."1.51The evolution of invasive cerebral vasospasm treatment in patients with spontaneous subarachnoid hemorrhage and delayed cerebral ischemia-continuous selective intracarotid nimodipine therapy in awake patients without sedation. ( Brand, C; Braun, M; Kapapa, T; König, R; Özpeynirci, Y; Paľa, A; Pedro, MT; Schmitz, B; Schneider, M; Wirtz, CR, 2019)
"Delayed Cerebral Infarction (DCI) due to Cerebral Vasospasm (CVS) is an important contributor to poor outcome after aneurysmal subarachnoid haemorrhage (aSAH)."1.51A novel rescue therapy for cerebral vasospasm: Cisternal Nimodipine application via stereotactic catheter ventriculocisternostomy. ( Coenen, VA; Reinacher, PC; Roelz, R; Scheiwe, C, 2019)
"Moreover, MN-08 also alleviated cerebral vasospasm in a cisterna magna single-injection model in rabbits."1.51The dual-functional memantine nitrate MN-08 alleviates cerebral vasospasm and brain injury in experimental subarachnoid haemorrhage models. ( Guo, B; Han, Y; Ju, J; Li, N; Li, S; Liu, Z; Luo, F; Mak, S; Sun, Y; Wang, Y; Wu, L; Yang, X; Zhang, G; Zhang, Z; Zhou, Q; Zhu, Z, 2019)
"Cerebral vasospasm is a major contributor to DCI and requires special attention."1.51Endovascular treatment of cerebral vasospasm after subarachnoid hemorrhage: More is more. ( Beck, J; Darkwah Oppong, M; Forsting, M; Jabbarli, R; Kaier, K; Mönninghoff, C; Pierscianek, D; Rölz, R; Shah, M; Sure, U; Taschner, C; Urbach, H, 2019)
"Nimodipine has improving effects on CVS in different degrees, and TCCS can be used to evaluate the therapeutic effects on CVS."1.46Evaluation function of transcranial two-dimensional and color Doppler ultrasonography (TCCS) for patients with different degrees of cerebral vasospasm before and after the nimodipine treatment. ( Li, X; Li, XN; Wang, JL; Yang, YL; Zhang, YH, 2017)
"Background Cerebral vasospasm (CV) is a major cause of delayed morbidity and mortality in patients with subarachnoid hemorrhage (SAH)."1.46Higher dose intra-arterial milrinone and intra-arterial combined milrinone-nimodipine infusion as a rescue therapy for refractory cerebral vasospasm. ( Dogan, R; Duman, E; Fırat, A; Karakoç, F; Pinar, HU; Yıldırım, E, 2017)
"Cerebral vasospasm following subarachnoid hemorrhage (SAH) is the most important complication that effects the mortality and morbidity of patients with intracranial aneurysm."1.46Comparison of the Effects and Mechanism of the Curcumin with Different Drugs in Experimental Vasospasm After Subarachnoid Hemorrhage. ( Aydin, HE; Baycu, C; Bektur, NE; Kilic, FS; Oner, S; Ozbek, Z, 2017)
"In aneurysmal subarachnoid haemorrhage cerebral vasospasm leads to clinical worsening and poor outcome."1.46Clinical Course and Monitoring Parameters After Continuous Interventional Intra-Arterial Treatment in Patients with Refractory Cerebral Vasospasm. ( Doukas, A; Jansen, O; Larsen, N; Mehdorn, M; Stopfer, A; Synowitz, M; von der Brelie, C, 2017)
"Timely detection of impending delayed cerebral ischemia after subarachnoid hemorrhage (SAH) is essential to improve outcome, but poses a diagnostic challenge."1.43Retinal Vessel Analysis (RVA) in the Context of Subarachnoid Hemorrhage - A Proof of Concept Study. ( Albanna, W; Brockmann, MA; Clusmann, H; Conzen, C; Fuest, M; Hoellig, A; Kotliar, K; Mueller, M; Schmidt-Trucksäss, A; Schubert, GA; Seiz, M; Thomé, C; Vilser, W; Weiss, M, 2016)
"Milrinone was recently suggested as an invasive VSP treatment option."1.42Repeated combined endovascular therapy with milrinone and nimodipine for the treatment of severe vasospasm: preliminary results. ( Karaic, R; Kleinpeter, G; Krafft, P; Loyoddin, M; Sherif, C; Tscholakoff, D; Valentin, A; Wambacher, B, 2015)
"Verapamil was the most common first-line therapy in the United States, whereas nimodipine was most popular in non-U."1.42Results of an International Survey on the Investigation and Endovascular Management of Cerebral Vasospasm and Delayed Cerebral Ischemia. ( Bulsara, KR; Chen, PR; Coulthard, A; Goddard, AJ; Hollingworth, M; Söderman, M, 2015)
" Key to the effective administration of continuous intra-arterial nimodipine is multimodal neuromonitoring and the individual adaptation of dosage and time of infusion for each patient."1.42Continuous intra-arterial nimodipine infusion in patients with severe refractory cerebral vasospasm after aneurysmal subarachnoid hemorrhage: a feasibility study and outcome results. ( Bele, S; Brawanski, A; Bründl, E; Hochreiter, A; Kieninger, M; Proescholdt, MA; Schebesch, KM; Scheitzach, J; Schneiker, A; Schödel, P; Schuierer, G; Wendl, C, 2015)
"Diffuse cerebral vasospasm is a rare complication following tumour resection."1.40Diffuse cerebral vasospasm following resection of a hypoglossal schwannoma in a child. ( Afshari, FT; Fernandes, HM; Fitzgerald, JJ; Garnett, MR; Higgins, JN; Santarius, T, 2014)
"The authors describe a rare case of central auditory dysfunction induced by cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH)."1.39Partly reversible central auditory dysfunction induced by cerebral vasospasm after subarachnoid hemorrhage. ( Deggouj, N; Duprez, T; Grandin, C; Hantson, P; Lhommel, R; Ponzetto, E; van Pesch, V; Vinetti, M, 2013)
"Cerebral vasospasm is a severe complication of subarachnoid hemorrhage (SAH)."1.39Dose-response relationship of locally applied nimodipine in an ex vivo model of cerebral vasospasm. ( Brockmann, C; Brockmann, MA; Groden, C; Hesser, J; Neumaier-Probst, E; Schubert, R; Seker, F, 2013)
"Twenty (20) patients with SAH were treated after their ruptured aneurysms had been secured."1.39Acupuncture for cerebral vasospasm after subarachnoid hemorrhage: a retrospective case-control study. ( Bae, HS; Cho, SY; Kim, GK; Ko, CN; Koh, JS; Lee, IW; Lee, SH; Park, JM; Park, SU, 2013)
"To determine if the age of packed red blood cells (PRBCs) is associated with adverse events or outcomes in patients with subarachnoid haemorrhage (SAH)."1.37Packed red blood cell age does not impact adverse events or outcomes after subarachnoid haemorrhage. ( Ault, ML; Duran, IM; Liebling, SM; Naidech, AM, 2011)
"Nimodipine treatment in cerebral vasospasm is useful."1.37Comparison of nimodipine delivery routes in cerebral vasospasm after subarachnoid hemorrhage: an experimental study in rabbits. ( Bilginer, B; Civelek, E; Isikay, I; Kircelli, A; Narin, F; Onal, MB; Solmaz, I; Ugurel, S; Yakupoglu, H, 2011)
"Nimodipine is an effect-proven agent in CVS, but dotarizine may take place of it."1.37Comparison of intrathecal dotarizine and nimodipine treatments in cerebral vasospasm after subarachnoid hemorrhage: an experimental study in rabbits. ( Civelek, E; Erdogan, E; Gonul, E; Izci, Y; Kircelli, A; Onal, MB; Solmaz, I; Tehli, O, 2011)
"Nimodipine is a potent drug for vessel relaxation, but side effects may preclude a sufficient dose."1.37Continuous local intra-arterial nimodipine administration in severe symptomatic vasospasm after subarachnoid hemorrhage. ( Coburger, J; Henkes, H; Hopf, N; Musahl, C; Vajda, Z, 2011)
"Cerebral vasospasm is the persistent constriction of large conduit arteries in the base of the brain."1.37Activation of vascular KCNQ (Kv7) potassium channels reverses spasmogen-induced constrictor responses in rat basilar artery. ( Brueggemann, LI; Byron, KL; Cribbs, LL; Mani, BK, 2011)
"Nonaneurysmal perimesencephalic subarachnoid hemorrhage (SAH) has usually a benign prognosis and uneventful course; however, recent reports suggest that these patients may develop severe symptomatic vasospasm."1.37Endovascular treatment of severe vasospasm in nonaneurysmal perimesencephalic subarachnoid hemorrhage. ( Dabus, G; Fuentes, K; Linfante, I; Samaniego, EA, 2011)
"Cerebral vasospasm complicating aneurysmal subarachnoid hemorrhage is a well-known medical entity."1.37Resistant vasospasm in subarachnoid hemorrhage treated with continuous intraarterial nimodipine infusion. ( Barth, H; Doukas, A; Jansen, O; Maslehaty, H; Mehdorn, HM; Petridis, AK, 2011)
" We describe a patient with an apparent primary TCH, which repeatedly occurred immediately after micturition until she achieved a therapeutic dosage of nimodipine."1.37Thunderclap headache triggered by micturition: responsive to nimodipine. ( Gui, W; Han, YY; Liu, YM; Wang, K; Wang, Y; Zhu, J, 2011)
"Brain hemodynamics in cerebral malaria (CM) is poorly understood, with apparently conflicting data showing microcirculatory hypoperfusion and normal or even increased blood flow in large arteries."1.36Murine cerebral malaria is associated with a vasospasm-like microcirculatory dysfunction, and survival upon rescue treatment is markedly increased by nimodipine. ( Cabrales, P; Carvalho, LJ; Frangos, JA; Meays, D; Zanini, GM, 2010)
" There were no serious adverse effects observed."1.35Feasibility and safety of intrathecal nimodipine on posthaemorrhagic cerebral vasospasm refractory to medical and endovascular therapy. ( Beseoglu, K; Hänggi, D; Steiger, HJ; Turowski, B, 2008)
"Rabbits symptomatic cerebral vasospasm model was built though Endo method, among the 40 rabbits, 8 died or had severe nervous system syndrome, the other 32 were randomly divided into 4 groups:group A, control group, injection of normal saline to the cisterna magna;group B, subarachnoid hemorrhage;group C, injection of human urinary tissue kallikreins;group D, treated with Nimodipine."1.35[Effects of human urinary tissue kallikreins on vasodilation of basilar artery in rabbits with symptomatic cerebral vasospasm]. ( Chen, WJ; Hu, ZY; Meng, YN; Mo, YC; Pei, SL; Wang, JL; Zhou, LP, 2009)
"Despite rigorous efforts, cerebral vasospasm remains an important cause of morbidity and mortality in patients who survive their initial subarachnoid hemorrhage."1.35Continuous intra-arterial infusion of nimodipine during embolization of cerebral aneurysms associated with vasospasm. ( Cinar, C; Oran, I, 2008)
"Here we describe a patient with a thunderclap headache and a mid-basilar narrowing due to a reversible vasospasm."1.33[Idiopathic thunderclap headache: reversible vasospasm of the Arteria basilaris]. ( Bruening, R; Plendl, H; Straube, A, 2006)
"Bathing headache is rarely described in literature."1.32Bathing headache: a variant of idiopathic thunderclap headache. ( Fuh, JL; Liao, YC; Lirng, JF; Lu, SR; Wang, SJ; Wu, ZA, 2003)
"During the following 2 weeks, the cerebral vasospasm resolved with application of high-dose methyl prednisolone and nimodipine."1.32[Cerebral vasospasms with hemodynamic infarctions as a complication of HELLP syndrome]. ( Bloos, G; Harscher, S; Möller, U; Pfleiderer, SO; Terborg, C; Witte, OW, 2003)
"The morbidity and mortality of cerebral vasospasm is significant."1.31Contemporary management of subarachnoid hemorrhage and vasospasm: the UIC experience. ( Alp, MS; Ausman, J; Charbel, F; Corsten, L; Debrun, G; Guppy, K; Misra, M; Raja, A; Roitberg, B, 2001)

Research

Studies (189)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (0.53)18.2507
2000's48 (25.40)29.6817
2010's96 (50.79)24.3611
2020's44 (23.28)2.80

Authors

AuthorsStudies
Opitz, M1
Zensen, S1
Bos, D1
Wetter, A1
Kleinschnitz, C1
Uslar, E1
Jabbarli, R2
Sure, U2
Radbruch, A1
Li, Y1
Dörner, N1
Forsting, M2
Deuschl, C1
Guberina, N1
Chen, M1
Zhang, Q1
Liu, H1
Zou, W1
Wei, X1
Roelz, R3
Scheiwe, C3
Grauvogel, J2
Csok, I2
Coenen, VA3
Beck, J3
Reinacher, PC3
Anthofer, J1
Bele, S3
Wendl, C3
Kieninger, M3
Zeman, F1
Bruendl, E1
Schmidt, NO1
Schebesch, KM2
Yindeedej, V1
Nimmannitya, P1
Noiphithak, R1
Punyarat, P1
Tantongtip, D1
Qureshi, AI1
Lobanova, I1
Huang, W1
Ishfaq, MF1
Broderick, JP1
Cassarly, CN1
Martin, RH1
Macdonald, RL7
Suarez, JI1
Tjerkstra, MA1
Verbaan, D1
Coert, BA1
Post, R1
van den Berg, R1
Coutinho, JM1
Horn, J1
Vandertop, WP1
Steiger, HJ7
Ensner, R1
Andereggen, L1
Remonda, L1
Berberat, J1
Marbacher, S2
Torregrossa, F1
Grasso, G1
Schacht, H4
Küchler, J3
Neumann, A4
Schramm, P4
Tronnier, VM2
Ditz, C3
Dayyani, M1
Sadeghirad, B1
Grotta, JC1
Zabihyan, S1
Ahmadvand, S1
Wang, Y6
Guyatt, GH1
Amin-Hanjani, S1
Geraldini, F1
De Cassai, A1
Diana, P1
Correale, C1
Boscolo, A1
Zampirollo, S1
Disarò, L1
Carere, A1
Cacco, N1
Navalesi, P1
Munari, M1
Mallereau, CH1
Ribeiro, M1
Ardellier, FD1
Dannhoff, G1
Cebula, H1
Proust, F1
Chibbaro, S1
Todeschi, J1
Kotwal, A1
Ramalingaiah, AH2
Shukla, D1
Radhakrishnan, M1
Konar, SK1
Srinivasaiah, B1
Chakrabarti, D1
Sundaram, M1
Romenskaya, T1
Longhitano, Y1
Piccolella, F1
Berger, JM1
Artico, M1
Taurone, S1
Maconi, A1
Saviano, A1
Caramuta, M1
Savioli, G1
Zanza, C1
Khanafer, A1
Cimpoca, A1
Bhogal, P1
Bäzner, H1
Ganslandt, O1
Henkes, H2
Fiamingo, G1
Canavero, I1
Gastaldi, M1
Coloberti, E1
Buongarzone, G1
Ghiotto, N1
Bacila, A1
Costa, A1
Ravaglia, S1
Collins, L1
Lam, L1
Kleinig, O1
Proudman, W1
Zhang, R1
Bagster, M1
Kovoor, J1
Gupta, A1
Goh, R1
Bacchi, S1
Schultz, D1
Kleinig, T1
Mehra, A1
Gomez, F1
Bischof, H1
Diedrich, D1
Laudanski, K1
Youm, JY1
Park, B1
Park, KH1
Il Won, Y1
Byoun, HS1
Lim, J1
Weber, W1
Jensen-Kondering, U1
Berlis, A1
Mindt, S1
Tokhi, U1
Hedtke, M1
Groß, HJ1
Hänggi, D10
Cottenceau, V1
Poutier, B1
Gariel, F1
Sauvage, N1
Petit, L1
Carrie, C1
Biais, M1
Hawkes, MA1
Hlavnicka, AA1
Wainsztein, NA1
Boppel, T1
Leppert, J1
Aulmann, L1
Küchler, JN1
Schaefer, JH1
Sajonz, B1
Steiert, C1
Buttler, J1
Rohr, E1
Shah, MJ1
Egger, K1
Niesen, WD1
Bardutzky, J1
Howarth, H1
Mandal, AKJ1
Boyd, E1
Missouris, CG1
Román, M2
Ramírez, JM1
Morales, M2
Crespo, MJ2
Carlson, AP1
Alchbli, A1
Shuttleworth, CW1
Solar, P1
Mackerle, Z1
Joukal, M1
Jancalek, R1
Liu, X1
Zhao, N1
Zeng, K1
Xiao, P1
Sheng, P1
Luo, X1
Isse, FA1
Abdallah, YEH1
Mahmoud, SH1
Chen, CT2
Chen, CC2
Wang, AY1
Wu, YM1
Chin, SC1
Hsieh, PC2
Yeap, MC1
Hsu, SY1
Lin, YJ1
Allen, A1
Raz, E1
Huang, P1
Rostanski, SK1
McGowan, B1
Khaira, G1
Coghlan, MA1
Shaibani, A1
Alden, TD1
Pardo, AC1
Schertz, AR1
Sarma, AK1
Datar, S1
Miller, PJ1
Viderman, D1
Sarria-Santamera, A1
Bilotta, F1
Morone, PJ1
Yan, W1
Adcock, J1
Komalavilas, P1
Mocco, J1
Thompson, RC1
Brophy, C1
Cheung-Flynn, J1
Mansoor, T1
Alsarah, AA1
Mousavi, H1
Khader Eliyas, J1
Girotra, T1
Hussein, O1
Wojcicki, KM1
Evans, RL1
Zwain, B1
Deputy, S1
García, L1
Samuelsson, J1
Sunila, M1
Rentzos, A1
Nilsson, D1
Albanna, W2
Weiss, M2
Conzen, C2
Clusmann, H2
Schneider, T1
Reinsch, M1
Müller, M1
Wiesmann, M1
Höllig, A1
Schubert, GA2
Kumar, A2
Phalak, M1
Nasri, A1
Mansour, M1
Kacem, A1
Zaouali, J1
Mrissa, R1
Wang, JL3
Li, XN1
Zhang, YH1
Li, X1
Yang, YL1
Flessa, J1
Lindenberg, N1
Redel, A1
Schneiker, A2
Schuierer, G2
Graf, B1
Silbereisen, V1
Nowack, MC1
Wolf, H1
Kurre, W1
Duman, E1
Karakoç, F1
Pinar, HU1
Dogan, R1
Fırat, A1
Yıldırım, E1
Sánchez Arguiano, J1
Hernández-Hernández, MA1
Jáuregui Solórzano, RA1
Maldonado-Vega, S1
González Mandly, A1
Burón Mediavilla, J1
Diringer, MN2
Zazulia, AR1
Zhang, C1
Zhao, S1
Zang, Y1
Zhao, W1
Song, Q1
Feng, S1
Hu, L1
Gu, F1
Tallarico, RT1
Pizzi, MA1
Freeman, WD1
Kraayvanger, L1
Berlit, P1
Albrecht, P1
Hartung, HP1
Kraemer, M1
Adami, D1
Berkefeld, J1
Platz, J1
Konczalla, J1
Pfeilschifter, W1
Weidauer, S1
Wagner, M1
Yi-Chou Wang, A1
Paľa, A1
Schneider, M1
Brand, C1
Pedro, MT1
Özpeynirci, Y1
Schmitz, B1
Wirtz, CR1
Kapapa, T1
König, R1
Braun, M1
Kumpinsky, A1
Nahas, SJ1
Al-Mufti, F1
Dodson, V1
Wajswol, E1
El-Ghanem, M1
Alchaki, A1
Nuoman, R1
Thabet, A1
Sutherland, A1
Roychowdhury, S1
Hidalgo, A1
Gupta, G1
Sriganesh, K1
Venkataramaiah, S1
Palaniswamy, SR1
Simonato, D1
Gabrieli, JD1
Cester, G1
Della Puppa, A1
Causin, F1
Silva, DP1
Soares, MF1
Almeida, V1
Fonseca, AC1
Qin, Y1
Li, G1
Sun, Z1
Xu, X1
Gu, J1
Gao, F1
Mitra, R1
Dube, SK1
Jain, V1
Luo, F1
Wu, L1
Zhang, Z2
Zhu, Z1
Liu, Z1
Guo, B1
Li, N1
Ju, J1
Zhou, Q1
Li, S1
Yang, X1
Mak, S1
Han, Y1
Sun, Y1
Zhang, G1
Pierscianek, D1
Rölz, R1
Darkwah Oppong, M1
Kaier, K1
Shah, M1
Taschner, C1
Mönninghoff, C1
Urbach, H1
Anand, S2
Goel, G2
Gupta, V2
Larrosa-Campo, D1
Ramon-Carbajo, C1
Benavente-Fernandez, L1
Alvarez-Escudero, R1
Zeidan-Ramon, N1
Calleja-Puerta, S1
Pascual, J1
Ponzetto, E1
Vinetti, M1
Grandin, C1
Duprez, T1
van Pesch, V1
Deggouj, N1
Lhommel, R1
Hantson, P1
Jaja, B1
Cusimano, MD1
Etminan, N2
Hasan, D1
Ilodigwe, D1
Lantigua, H1
Le Roux, P1
Lo, B1
Louffat-Olivares, A1
Mayer, S1
Molyneux, A1
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Schweizer, TA1
Schenk, T1
Spears, J1
Todd, M1
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Vergouwen, MD1
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Singh, J1
Rank, W1
Afshari, FT1
Fitzgerald, JJ1
Higgins, JN1
Garnett, MR1
Fernandes, HM1
Santarius, T1
Rozen, TD1
Beams, JL1
Chowdhury, T1
Schaller, B1
Ott, S1
Jedlicka, S1
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Peter, M1
Pudenz, C1
Merker, P1
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Lumenta, CB2
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Kasuya, H1
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Pfleiderer, SO1
Terborg, C1
LeStrange, DG1
Han, RQ1
Wang, BG1
Li, SR1
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Zhao, JZ1
Hui, C1
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Sakowitz, OW1
Unterberg, AW1
Biondi, A1
Le Jean, L1
Puybasset, L2
Laslo, AM1
Eastwood, JD1
Chen, FX1
Lee, TY1
Inzitari, D1
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Schmid-Elsaesser, R1
Kunz, M1
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Prueckner, S1
Briegel, J1
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Mesis, RG1
Wang, H1
Lombard, FW1
Yates, R1
Vitek, MP1
Borel, CO1
Warner, DS1
Laskowitz, DT1
van den Bergh, WM1
Mees, SM1
Rinkel, GJ1
Jiang, WJ1
Du, B1
Leung, TW1
Xu, XT1
Jin, M1
Dong, KH1
Mehta, AK1
Yadav, KS1
Sawant, KK1
Keyrouz, SG1
Tavernier, B1
Decamps, F1
Vega, E1
Poidevin, P1
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Abdennour, L1
Lejean, L1
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Graupner, T1
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Yong, M1
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Koivukangas, P1
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Koivukangas, J1
Ohman, J1
Matula, C2
Egge, A1
Waterloo, K1
Sjøholm, H1
Solberg, T1
Ingebrigtsen, T1
Corsten, L1
Raja, A1
Guppy, K1
Roitberg, B1
Misra, M1
Alp, MS1
Charbel, F1
Debrun, G1
Ausman, J1
Schoeggl, A1
Stachura, K1
Danilewicz, B1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Inter- and Intra-Observer Variability in Transcranial Doppler (TCD) Technique in Neurocritical Care Patients[NCT04583163]12 participants (Anticipated)Observational2020-09-22Recruiting
Cerebral Aneurysms: a Retrospective Study on the Experience in Our Hospital With a Comparative Analysis Between the Different Techniques Used in Its Treatment[NCT04792944]247 participants (Actual)Observational2007-01-01Completed
Effect of Superior Cervical Sympathetic Block Versus Stellate Ganglion Block to Treat Cerebral Vasospasm in Patients With Refractory Post-traumatic Subarachnoid Hemorrhage.[NCT06134583]60 participants (Anticipated)Interventional2023-12-31Not yet recruiting
Neuroprotective Effect of Dapsone in Patients With Aneurysmal Subarachnoid Hemorrhage: Prospective, Randomized, Double-Blinded, Placebo-Controlled, Clinical Trial[NCT05131295]Phase 349 participants (Actual)Interventional2007-09-05Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

30 reviews available for nimodipine and Angiospasm, Intracranial

ArticleYear
Lessons Learned from Phase II and Phase III Trials Investigating Therapeutic Agents for Cerebral Ischemia Associated with Aneurysmal Subarachnoid Hemorrhage.
    Neurocritical care, 2022, Volume: 36, Issue:2

    Topics: Brain Ischemia; Cerebral Infarction; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III

2022
Therapeutic Approaches for Cerebrovascular Dysfunction After Aneurysmal Subarachnoid Hemorrhage: An Update and Future Perspectives.
    World neurosurgery, 2022, Volume: 159

    Topics: Brain Injuries; Brain Ischemia; Cerebral Infarction; Humans; Nimodipine; Quality of Life; Subarachno

2022
Prophylactic Therapies for Morbidity and Mortality After Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Network Meta-Analysis of Randomized Trials.
    Stroke, 2022, Volume: 53, Issue:6

    Topics: Adult; Brain Ischemia; Cilostazol; Humans; Magnesium; Morbidity; Network Meta-Analysis; Nicardipine;

2022
A Comparison Between Enteral and Intravenous Nimodipine in Subarachnoid Hemorrhage: A Systematic Review and Network Meta-Analysis.
    Neurocritical care, 2022, Volume: 36, Issue:3

    Topics: Brain Ischemia; Cerebral Infarction; Humans; Network Meta-Analysis; Nimodipine; Randomized Controlle

2022
Delayed cerebral ischemia after meningioma resection: Literature review and illustrative case.
    Neuro-Chirurgie, 2022, Volume: 68, Issue:5

    Topics: Brain Ischemia; Humans; Meningeal Neoplasms; Meningioma; Middle Aged; Nimodipine; Paresis; Platelet

2022
Cerebral Vasospasm: Practical Review of Diagnosis and Management.
    Reviews on recent clinical trials, 2023, Volume: 18, Issue:1

    Topics: Brain Injuries; Humans; Nimodipine; Subarachnoid Hemorrhage; Treatment Outcome; Vasospasm, Intracran

2023
HaNDL syndrome: a reversible cerebral vasoconstriction triggered by an infection? A case report and a case-based review.
    European journal of medical research, 2022, Oct-08, Volume: 27, Issue:1

    Topics: Adult; Albumins; Calcium Channel Blockers; Epstein-Barr Virus Nuclear Antigens; Headache; Humans; Im

2022
Verapamil in the treatment of reversible cerebral vasoconstriction syndrome: A systematic review.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2023, Volume: 113

    Topics: Cerebrovascular Disorders; Humans; Nimodipine; Vasoconstriction; Vasospasm, Intracranial; Verapamil

2023
Cortical Spreading Depolarization and Delayed Cerebral Ischemia; Rethinking Secondary Neurological Injury in Subarachnoid Hemorrhage.
    International journal of molecular sciences, 2023, Jun-08, Volume: 24, Issue:12

    Topics: Autonomic Nervous System Diseases; Brain; Brain Ischemia; Cerebral Infarction; Humans; Nimodipine; S

2023
Non-steroidal anti-inflammatory drugs in the pathophysiology of vasospasms and delayed cerebral ischemia following subarachnoid hemorrhage: a critical review.
    Neurosurgical review, 2021, Volume: 44, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Brain Ischemia; Double-Blind Method; Humans; Nimodipine; Ra

2021
Side effects of continuous intra-arterial infusion of nimodipine for management of resistant cerebral vasospasm in subarachnoid hemorrhage patients: A systematic review.
    Neuro-Chirurgie, 2021, Volume: 67, Issue:5

    Topics: Humans; Infusions, Intra-Arterial; Nimodipine; Retrospective Studies; Subarachnoid Hemorrhage; Vasos

2021
Aneurysmal Subarachnoid Hemorrhage: Strategies for Preventing Vasospasm in the Intensive Care Unit.
    Seminars in respiratory and critical care medicine, 2017, Volume: 38, Issue:6

    Topics: Calcium Channel Blockers; Delayed-Action Preparations; Humans; Intensive Care Units; Intracranial An

2017
Investigational drugs for vasospasm after subarachnoid hemorrhage.
    Expert opinion on investigational drugs, 2018, Volume: 27, Issue:4

    Topics: Animals; Brain Ischemia; Drug Design; Drugs, Investigational; Humans; Neuroprotective Agents; Nimodi

2018
Coadjuvant Treatment of Vasospasm in Ruptured Unsecured Cerebral Aneurysms with Aggressive Angioplasty, Intra-Arterial Nimodipine, and Aneurysm Embolization.
    World neurosurgery, 2018, Volume: 116

    Topics: Adult; Aged; Aneurysm, Ruptured; Angioplasty; Combined Modality Therapy; Embolization, Therapeutic;

2018
Bath-Related Headache.
    Current pain and headache reports, 2018, Aug-02, Volume: 22, Issue:10

    Topics: Animals; Antihypertensive Agents; Headache; Headache Disorders, Primary; Humans; Nimodipine; Vasocon

2018
SAHIT Investigators--on the outcome of some subarachnoid hemorrhage clinical trials.
    Translational stroke research, 2013, Volume: 4, Issue:3

    Topics: Antioxidants; Brain Infarction; Calcium Channel Blockers; Critical Care; Dioxanes; Drug Therapy, Com

2013
Management of delayed cerebral ischemia after subarachnoid hemorrhage.
    Critical care (London, England), 2016, Oct-14, Volume: 20, Issue:1

    Topics: Brain Ischemia; Calcium Channel Blockers; Disease Management; Humans; Hyponatremia; Hypotension; Hyp

2016
Evidence-based pharmacotherapy for cerebral vasospasm.
    Neurological research, 2009, Volume: 31, Issue:6

    Topics: Animals; Cardiovascular Agents; Enoxaparin; Evidence-Based Medicine; Humans; Hydroxymethylglutaryl-C

2009
Reversible cerebral vasoconstriction syndrome.
    Practical neurology, 2009, Volume: 9, Issue:5

    Topics: Age of Onset; Cerebral Angiography; Female; Humans; Male; Nimodipine; Sex Factors; Stroke; Subarachn

2009
Neuroanesthesiology update.
    Journal of neurosurgical anesthesiology, 2010, Volume: 22, Issue:2

    Topics: Anesthesia; Anesthesiology; Animals; Anticonvulsants; Brain; Calcium Channel Blockers; Electroenceph

2010
Role of intraarterial therapy for cerebral vasospasm secondary to aneurysmal subarachnoid hemorrhage.
    Pharmacotherapy, 2010, Volume: 30, Issue:4

    Topics: Calcium Channel Blockers; Clinical Trials as Topic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhi

2010
Management of delayed cerebral ischemia after subarachnoid hemorrhage.
    Continuum (Minneapolis, Minn.), 2012, Volume: 18, Issue:3

    Topics: Angioplasty, Balloon; Brain Ischemia; Calcium Channel Blockers; Cardiovascular Agents; Cerebral Angi

2012
Intracranial drug delivery for subarachnoid hemorrhage.
    Therapeutic delivery, 2012, Volume: 3, Issue:1

    Topics: Brain Ischemia; Cerebral Infarction; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug De

2012
Therapeutic approaches to vasospasm in subarachnoid hemorrhage.
    Current opinion in critical care, 2002, Volume: 8, Issue:2

    Topics: Angioplasty, Balloon; Blood Volume; Calcium Channel Blockers; Fibrinolytic Agents; Fluid Therapy; He

2002
Detecting and treating microvascular ischemia after subarachnoid hemorrhage.
    Current opinion in critical care, 2006, Volume: 12, Issue:2

    Topics: Antihypertensive Agents; Cerebrovascular Circulation; Hemodilution; Humans; Hypoxia-Ischemia, Brain;

2006
Calcium channel blockers and stroke.
    Aging clinical and experimental research, 2005, Volume: 17, Issue:4 Suppl

    Topics: Aged; Antihypertensive Agents; Atherosclerosis; Calcium Channel Blockers; Dementia, Vascular; Humans

2005
Clinical review: Prevention and therapy of vasospasm in subarachnoid hemorrhage.
    Critical care (London, England), 2007, Volume: 11, Issue:4

    Topics: Angioplasty, Balloon; Calcium Channel Blockers; Cerebral Angiography; Endothelin-1; Humans; Hydroxym

2007
Subarachnoid hemorrhage and cerebral vasospasm--facts and perspectives.
    Wiener klinische Wochenschrift, 2000, Jun-16, Volume: 112, Issue:12

    Topics: Adolescent; Adult; Age Factors; Austria; Calcium Channel Blockers; Drug Therapy, Combination; Female

2000
Cerebral protection before, during and after neurosurgical procedures.
    Stereotactic and functional neurosurgery, 2000, Volume: 75, Issue:2-3

    Topics: Amino Acids; Brain Damage, Chronic; Calcium Channel Blockers; Clinical Trials as Topic; Cognition Di

2000
[Cerebral vasospasm after subarachnoid hemorrhage. Current possibilities of prevention and treatment].
    Przeglad lekarski, 2002, Volume: 59, Issue:1

    Topics: Aneurysm, Ruptured; Humans; Neuroprotective Agents; Nimodipine; Pregnatrienes; Subarachnoid Hemorrha

2002

Trials

17 trials available for nimodipine and Angiospasm, Intracranial

ArticleYear
Clinical Outcome in Cerebral Vasospasm Patients Treated with and without Intra-Arterial Nimodipine Infusion.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2022, Volume: 83, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Humans; Middle Aged; Nimodipine; Prospective Studies; Re

2022
Effect of Locally Delivered Nimodipine Microparticles on Spreading Depolarization in Aneurysmal Subarachnoid Hemorrhage.
    Neurocritical care, 2021, Volume: 34, Issue:1

    Topics: Brain; Brain Ischemia; Electrocorticography; Humans; Nimodipine; Subarachnoid Hemorrhage; Vasospasm,

2021
Magnesium sulfate in combination with nimodipine for the treatment of subarachnoid hemorrhage: a randomized controlled clinical study.
    Neurological research, 2018, Volume: 40, Issue:4

    Topics: Adult; Brain Ischemia; Cerebral Infarction; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Long-Term, Continuous Intra-Arterial Nimodipine Treatment of Severe Vasospasm After Aneurysmal Subarachnoid Hemorrhage.
    World neurosurgery, 2016, Volume: 88

    Topics: Adult; Cohort Studies; Drug Administration Schedule; Feasibility Studies; Female; Humans; Infusions,

2016
Nimodipine in aneurysmal subarachnoid hemorrhage: a randomized study of intravenous or peroral administration.
    Journal of neurosurgery, 2009, Volume: 110, Issue:1

    Topics: Administration, Oral; Aged; Calcium Channel Blockers; Endpoint Determination; Female; Follow-Up Stud

2009
A multimodal concept in patients after severe aneurysmal subarachnoid hemorrhage: results of a controlled single centre prospective randomized multimodal phase I/II trial on cerebral vasospasm.
    Central European neurosurgery, 2009, Volume: 70, Issue:2

    Topics: Adult; Aged; Calcium Channel Blockers; Combined Modality Therapy; Female; Humans; Male; Middle Aged;

2009
Continuous intra-arterial infusion of nimodipine at the onset of resistant vasospasm in aneurysmal subarachnoidal haemorrhage. Technical report.
    Neurological research, 2011, Volume: 33, Issue:3

    Topics: Antihypertensive Agents; Coronary Angiography; Female; Humans; Infusions, Intra-Arterial; Male; Midd

2011
Efficacy and safety of fasudil in patients with subarachnoid hemorrhage: final results of a randomized trial of fasudil versus nimodipine.
    Neurologia medico-chirurgica, 2011, Volume: 51, Issue:10

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Aged; Brain Ischemia; Calcium Channel Blockers

2011
Mechanism and treatment principle for cerebral vessel spasm caused by concussion.
    Chinese journal of traumatology = Zhonghua chuang shang za zhi, 2002, Volume: 5, Issue:6

    Topics: Adolescent; Adult; Aged; Blood Flow Velocity; Brain Concussion; Cerebral Arteries; Cerebrovascular C

2002
Factors associated with the development of vasospasm after planned surgical treatment of aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2003, Volume: 99, Issue:4

    Topics: Adult; Aged; Combined Modality Therapy; Double-Blind Method; Drug Therapy, Combination; Female; Huma

2003
Nimodipine for treatment of primary thunderclap headache.
    Neurology, 2004, Apr-27, Volume: 62, Issue:8

    Topics: Administration, Oral; Adult; Aged; Brain; Cerebral Angiography; Female; Headache; Humans; Injections

2004
[The effect of intraoperative continuous nimodipine infusion on cerebral vasospasm during intracranial aneurysm surgery].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2004, Dec-22, Volume: 42, Issue:24

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Intravenous; Female; Huma

2004
Intravenous magnesium versus nimodipine in the treatment of patients with aneurysmal subarachnoid hemorrhage: a randomized study.
    Neurosurgery, 2006, Volume: 58, Issue:6

    Topics: Adult; Aged; Brain Ischemia; Calcium Channel Blockers; Cerebral Angiography; Cerebral Infarction; Fe

2006
Effect of fasudil hydrochloride, a protein kinase inhibitor, on cerebral vasospasm and delayed cerebral ischemic symptoms after aneurysmal subarachnoid hemorrhage.
    Neurologia medico-chirurgica, 2006, Volume: 46, Issue:9

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Brain Ischemia; Female; Humans; Male; Middle A

2006
Intra-arterial nimodipine for severe cerebral vasospasm after aneurysmal subarachnoid hemorrhage: influence on clinical course and cerebral perfusion.
    AJNR. American journal of neuroradiology, 2008, Volume: 29, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cerebrovascular Circulation; Female; Humans; Injections, Intra-Arter

2008
Cost-effectiveness analysis of nimodipine treatment after aneurysmal subarachnoid hemorrhage and surgery.
    Neurosurgery, 1999, Volume: 45, Issue:4

    Topics: Adolescent; Adult; Aged; Aneurysm, Ruptured; Combined Modality Therapy; Cost-Benefit Analysis; Doubl

1999
Prophylactic hyperdynamic postoperative fluid therapy after aneurysmal subarachnoid hemorrhage: a clinical, prospective, randomized, controlled study.
    Neurosurgery, 2001, Volume: 49, Issue:3

    Topics: Aged; Brain; Brain Ischemia; Cognition Disorders; Echoencephalography; Female; Fluid Therapy; Follow

2001

Other Studies

142 other studies available for nimodipine and Angiospasm, Intracranial

ArticleYear
Radiation exposure in the intra-arterial nimodipine therapy of subarachnoid hemorrhage related cerebral vasospasm.
    Journal of radiological protection : official journal of the Society for Radiological Protection, 2022, Jan-18, Volume: 42, Issue:1

    Topics: Humans; Nimodipine; Radiation Exposure; Retrospective Studies; Subarachnoid Hemorrhage; Treatment Ou

2022
Influence of nimodipine combined with ulinastatin on neurological function and inflammatory reaction in patients with cerebral vasospasm after subarachnoid hemorrhage.
    Clinical neurology and neurosurgery, 2021, Volume: 210

    Topics: Adult; Blood Flow Velocity; Cerebral Arteries; Drug Therapy, Combination; Female; Glycoproteins; Hum

2021
Early cisternal fibrinolysis is more effective than rescue spasmolysis for the prevention of delayed infarction after subarachnoid haemorrhage.
    Stroke and vascular neurology, 2022, Volume: 7, Issue:2

    Topics: Cerebral Infarction; Fibrinolysis; Humans; Nimodipine; Parasympatholytics; Retrospective Studies; Su

2022
Continuous intra-arterial nimodipine infusion as rescue treatment of severe refractory cerebral vasospasm after aneurysmal subarachnoid hemorrhage.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2022, Volume: 96

    Topics: Humans; Infusions, Intra-Arterial; Nimodipine; Quality of Life; Retrospective Studies; Subarachnoid

2022
Large practice variations in diagnosis and treatment of delayed cerebral ischemia after subarachnoid hemorrhage.
    World neurosurgery, 2022, Volume: 160

    Topics: Brain Ischemia; Cerebral Infarction; Humans; Nimodipine; Subarachnoid Hemorrhage; Vasospasm, Intracr

2022
Hemodynamic response and clinical outcome following intravenous milrinone plus norepinephrine-based hyperdynamic hypertensive therapy in patients suffering secondary cerebral ischemia after aneurysmal subarachnoid hemorrhage.
    Acta neurochirurgica, 2022, Volume: 164, Issue:3

    Topics: Brain Ischemia; Cerebral Infarction; Hemodynamics; Humans; Hypertension; Milrinone; Nimodipine; Nore

2022
Analysis of Angiographic Treatment Response to Intra-Arterial Nimodipine Bolus Injection in Patients with Medically Refractory Cerebral Vasospasm After Spontaneous Subarachnoid Hemorrhage.
    World neurosurgery, 2022, Volume: 162

    Topics: Aged; Brain Ischemia; Cerebral Infarction; Humans; Infarction; Nimodipine; Retrospective Studies; Su

2022
Role of Nimodipine and Milrinone in Delayed Cerebral Ischemia.
    World neurosurgery, 2022, Volume: 166

    Topics: Brain Ischemia; Cerebral Infarction; Humans; Milrinone; Nimodipine; Subarachnoid Hemorrhage; Vasospa

2022
Intracranial stenting as a bail-out option for posthemorrhagic cerebral vasospasm: a single-center experience with long-term follow-up.
    BMC neurology, 2022, Sep-15, Volume: 22, Issue:1

    Topics: Aortic Aneurysm, Abdominal; Blood Vessel Prosthesis Implantation; Endovascular Procedures; Eptifibat

2022
Vasodilatory effects of tadalafil in an animal model of cerebral vasospasm: Comparative analysis with oral nimodipine.
    Clinical neurology and neurosurgery, 2023, Volume: 232

    Topics: Animals; Humans; Models, Animal; Nimodipine; Rabbits; Subarachnoid Hemorrhage; Tadalafil; Treatment

2023
Evaluation of DeGIR registry data on endovascular treatment of cerebral vasospasm in Germany 2018-2021: an overview of the current care situation.
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2023, Volume: 195, Issue:11

    Topics: Endovascular Procedures; Female; Humans; Male; Nimodipine; Papaverine; Retrospective Studies; Routin

2023
Mass spectrometry-based method for quantification of nimodipine and glutamate in cerebrospinal fluid. Pilot study with patients after aneurysmal subarachnoid haemorrhage.
    Journal of clinical pharmacy and therapeutics, 2020, Volume: 45, Issue:1

    Topics: Adult; Aged; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Female; Glutamic Acid;

2020
May levosimendan be safe and effective in refractory vasospasm despite adequate treatment with repeated angiography and milrinone infusion after subarachnoid haemorrhage?
    Anaesthesia, critical care & pain medicine, 2019, Volume: 38, Issue:6

    Topics: Aneurysm, Ruptured; Cardiotonic Agents; Cerebral Angiography; Cerebrospinal Fluid Leak; Computed Tom

2019
Reversible Cerebral Vasoconstriction Syndrome Responsive to Intravenous Milrinone.
    Neurocritical care, 2020, Volume: 32, Issue:1

    Topics: Adult; Angiography, Digital Subtraction; Aphasia, Broca; Brain Edema; Cerebral Hemorrhage; Computed

2020
Transluminal balloon angioplasty for cerebral vasospasm after spontaneous subarachnoid hemorrhage: A single-center experience.
    Clinical neurology and neurosurgery, 2020, Volume: 188

    Topics: Adult; Angioplasty, Balloon; Brain Infarction; Brain Ischemia; Cerebral Angiography; Endovascular Pr

2020
Symptomatic Cerebral Vasospasm after Spontaneous Subarachnoid Hemorrhage: Comparison of Single and Multiple Intra-arterial Treatment with Respect to the Functional Outcome.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2020, Volume: 81, Issue:3

    Topics: Aged; Angioplasty; Female; Humans; Male; Middle Aged; Nimodipine; Prognosis; Retrospective Studies;

2020
Impact of Stereotactic Ventriculocisternostomy on Delayed Cerebral Infarction and Outcome After Subarachnoid Hemorrhage.
    Stroke, 2020, Volume: 51, Issue:2

    Topics: Aged; Aneurysm, Ruptured; Cerebral Infarction; Female; Fibrinolytic Agents; Humans; Intracranial Ane

2020
Reversible Cerebral Vasoconstriction Syndrome: Perhaps Not So Reversible?
    The American journal of medicine, 2020, Volume: 133, Issue:8

    Topics: Adult; Computed Tomography Angiography; Female; Headache Disorders, Primary; Humans; Nimodipine; Vas

2020
Significant reduction of vascular reactivity with dantrolene and nimodipine in diabetic rats: a potential approach to cerebral vasospasm management in diabetes.
    Pharmacological reports : PR, 2020, Volume: 72, Issue:1

    Topics: Acetylcholine; Animals; Dantrolene; Diabetes Mellitus, Experimental; Dose-Response Relationship, Dru

2020
Effects of nimodipine combined with betahistine on CRP and other inflammatory cytokines and vascular endothelial function in patients with hypertensive cerebral vasospasm.
    Clinical hemorheology and microcirculation, 2020, Volume: 75, Issue:3

    Topics: Aged; Antihypertensive Agents; Betahistine; C-Reactive Protein; Cytokines; Female; Humans; Hypertens

2020
The Impact of Nimodipine Administration through Feeding Tube on Outcomes in Patients with Aneurysmal Subarachnoid Hemorrhage.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2020, Volume: 23, Issue:1

    Topics: Administration, Oral; Adult; Aged; Brain Ischemia; Drug Administration Schedule; Enteral Nutrition;

2020
Early strategy of scepter XC balloon angioplasty and simultaneous Nimodipine infusion for vasospasm following ruptured aneurysm.
    BMC neurology, 2020, Jul-07, Volume: 20, Issue:1

    Topics: Adult; Aged; Aneurysm, Ruptured; Angioplasty, Balloon; Computed Tomography Angiography; Female; Huma

2020
Large Subcortical Intracerebral Hemorrhage Because of Reversible Cerebral Vasoconstriction Syndrome: A Case Study.
    Stroke, 2020, Volume: 51, Issue:11

    Topics: Adult; Aneurysm, False; Cerebral Angiography; Cerebral Hemorrhage; Computed Tomography Angiography;

2020
Use of Nimodipine in a Neonate With Cerebral Vasospasm With Delayed Ischemia From Subarachnoid Hemorrhage in the Posterior Fossa.
    Pediatric neurology, 2020, Volume: 111

    Topics: Angiography, Digital Subtraction; Brain Ischemia; Cerebral Angiography; Cranial Fossa, Posterior; Hu

2020
Reversible cerebral vasoconstriction syndrome (RCVS) caused by over-the-counter calcium supplement ingestion.
    BMJ case reports, 2021, Jan-28, Volume: 14, Issue:1

    Topics: Antacids; Brain; Calcium Carbonate; Calcium Channel Blockers; Cerebral Angiography; Computed Tomogra

2021
Vasorelaxing cell permeant phosphopeptide mimetics for subarachnoid hemorrhage.
    European journal of pharmacology, 2021, Jun-05, Volume: 900

    Topics: Animals; Cell Adhesion Molecules; Cyclic GMP-Dependent Protein Kinases; Down-Regulation; Drug Design

2021
COVID-19 Associated Reversible Cerebral Vasoconstriction Syndrome Successfully Treated with Nimodipine and Aspirin.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2021, Volume: 30, Issue:7

    Topics: Adult; Aspirin; Cerebral Arteries; COVID-19; Female; Humans; Nimodipine; Syndrome; Treatment Outcome

2021
Micturition induced primary thunderclap headache in an 11-year-old with response to nimodipine.
    Journal of the neurological sciences, 2021, 07-15, Volume: 426

    Topics: Child; Headache Disorders, Primary; Humans; Nimodipine; Urination; Vasospasm, Intracranial

2021
The combination of dantrolene and nimodipine effectively reduces 5-HT-induced vasospasms in diabetic rats.
    Scientific reports, 2021, 05-10, Volume: 11, Issue:1

    Topics: Animals; Calcium Channel Blockers; Dantrolene; Diabetes Mellitus, Experimental; Drug Therapy, Combin

2021
Intra-arterial nimodipine for severe cerebral vasospasm after aneurysmal subarachnoid haemorrhage - neurological and radiological outcome.
    The neuroradiology journal, 2022, Volume: 35, Issue:2

    Topics: Humans; Nimodipine; Retrospective Studies; Subarachnoid Hemorrhage; Treatment Outcome; Vasodilator A

2022
Systemic and Cerebral Concentration of Nimodipine During Established and Experimental Vasospasm Treatment.
    World neurosurgery, 2017, Volume: 102

    Topics: Aged; Cerebral Cortex; Chromatography, Liquid; Dose-Response Relationship, Drug; Female; Humans; Mal

2017
Is intra arterial nimodipine really beneficial in vasospasm following aneurysmal subarachnoid hemorrhage?
    British journal of neurosurgery, 2017, Volume: 31, Issue:3

    Topics: Humans; Nimodipine; Subarachnoid Hemorrhage; Vasodilator Agents; Vasospasm, Intracranial

2017
Reversible cerebral vasoconstriction syndrome and antivitamin K anticoagulation: challenges of an unusual association.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2017, Volume: 38, Issue:9

    Topics: 4-Hydroxycoumarins; Adult; Anticoagulants; Constriction, Pathologic; Female; Headache Disorders, Pri

2017
Evaluation function of transcranial two-dimensional and color Doppler ultrasonography (TCCS) for patients with different degrees of cerebral vasospasm before and after the nimodipine treatment.
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:11

    Topics: Adult; Aged; Blood Flow Velocity; Female; Hemodynamics; Humans; Male; Middle Aged; Middle Cerebral A

2017
Side Effects of Long-Term Continuous Intra-arterial Nimodipine Infusion in Patients with Severe Refractory Cerebral Vasospasm after Subarachnoid Hemorrhage.
    Neurocritical care, 2018, Volume: 28, Issue:1

    Topics: Adult; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Infusions, Intra-Arterial; M

2018
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2018, Volume: 190, Issue:1

    Topics: Adult; Cerebral Angiography; Computed Tomography Angiography; Diagnosis, Differential; Headache Diso

2018
Higher dose intra-arterial milrinone and intra-arterial combined milrinone-nimodipine infusion as a rescue therapy for refractory cerebral vasospasm.
    Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2017, Volume: 23, Issue:6

    Topics: Angiography, Digital Subtraction; Cerebral Angiography; Computed Tomography Angiography; Drug Therap

2017
Stellate ganglion block as rescue therapy in refractory vasospasm after subarachnoid hemorrhage.
    Medicina intensiva, 2019, Volume: 43, Issue:7

    Topics: Anesthetics, Local; Aneurysm, Ruptured; Arm; Bupivacaine; Humans; Intracranial Aneurysm; Middle Aged

2019
Cerebrospinal fluid findings in reversible cerebral vasoconstriction syndrome: a way to differentiate from cerebral vasculitis?
    Clinical and experimental immunology, 2018, Volume: 193, Issue:3

    Topics: Adult; Angiography; Cell Count; Cerebrospinal Fluid; Diagnosis, Differential; Female; Headache; Huma

2018
Complication rate of intraarterial treatment of severe cerebral vasospasm after subarachnoid hemorrhage with nimodipine and percutaneous transluminal balloon angioplasty: Worth the risk?
    Journal of neuroradiology = Journal de neuroradiologie, 2019, Volume: 46, Issue:1

    Topics: Adult; Aged; Angioplasty; Aortic Dissection; Cerebral Infarction; Combined Modality Therapy; Female;

2019
The evolution of invasive cerebral vasospasm treatment in patients with spontaneous subarachnoid hemorrhage and delayed cerebral ischemia-continuous selective intracarotid nimodipine therapy in awake patients without sedation.
    Neurosurgical review, 2019, Volume: 42, Issue:2

    Topics: Aged; Brain Ischemia; Calcium Channel Blockers; Carotid Arteries; Feasibility Studies; Female; Human

2019
Chemical angioplasty for medically refractory reversible cerebral vasoconstriction syndrome
    British journal of neurosurgery, 2018, Volume: 32, Issue:4

    Topics: Angioplasty; Calcium Channel Blockers; Drug Resistance; Female; Humans; Infusions, Intra-Arterial; M

2018
Effect of Intra-arterial Nimodipine on Cerebral Oxygen Saturation and Systemic Hemodynamic Indices in Patients With Cerebral Vasospasm: A Prospective Cohort Study.
    Journal of neurosurgical anesthesiology, 2020, Volume: 32, Issue:2

    Topics: Brain; Cohort Studies; Female; Hemodynamics; Humans; Male; Middle Aged; Nimodipine; Oxygen; Prospect

2020
Intracranial stenting after tumor exeresis complicated by delayed kinking of the middle cerebral artery.
    Acta neurochirurgica, 2019, Volume: 161, Issue:3

    Topics: Aged; Cerebral Revascularization; Humans; Male; Meningeal Neoplasms; Meningioma; Middle Cerebral Art

2019
A novel rescue therapy for cerebral vasospasm: Cisternal Nimodipine application via stereotactic catheter ventriculocisternostomy.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 63

    Topics: Catheters; Cerebral Infarction; Female; Humans; Imaging, Three-Dimensional; Male; Middle Aged; Nimod

2019
Chronic headache with vasospasm treated with nimodipine.
    Journal of neurology, 2019, Volume: 266, Issue:6

    Topics: Female; Headache Disorders; Humans; Magnetic Resonance Imaging; Middle Aged; Nimodipine; Ultrasonogr

2019
Comparison of the effects of nimodipine and deferoxamine on brain injury in rat with subarachnoid hemorrhage.
    Behavioural brain research, 2019, 07-23, Volume: 367

    Topics: Animals; Atrophy; Cognitive Dysfunction; Deferoxamine; Disease Models, Animal; Ferritins; Male; Maze

2019
Isolated diastolic hypotension: A unique complication of intra-arterial nimodipine infusion!!
    Journal of clinical anesthesia, 2020, Volume: 59

    Topics: Aged; Angiography, Digital Subtraction; Anterior Cerebral Artery; Blood Pressure; Diastole; Electroc

2020
The dual-functional memantine nitrate MN-08 alleviates cerebral vasospasm and brain injury in experimental subarachnoid haemorrhage models.
    British journal of pharmacology, 2019, Volume: 176, Issue:17

    Topics: Animals; Brain Injuries; Disease Models, Animal; Dose-Response Relationship, Drug; HEK293 Cells; Hum

2019
Endovascular treatment of cerebral vasospasm after subarachnoid hemorrhage: More is more.
    Neurology, 2019, 07-30, Volume: 93, Issue:5

    Topics: Adult; Aged; Angioplasty, Balloon; Arterial Pressure; Brain Ischemia; Endovascular Procedures; Femal

2019
Continuous intra-arterial dilatation with nimodipine and milrinone for refractory cerebral vasospasm.
    Journal of neurosurgical anesthesiology, 2014, Volume: 26, Issue:1

    Topics: Angioplasty, Balloon; Cerebral Angiography; Dilatation; Drug Resistance; Female; Humans; Infusions,

2014
[Diagnosis of stroke due to cocaine and its complications].
    Revista de neurologia, 2013, Aug-16, Volume: 57, Issue:4

    Topics: Adult; Aphasia; Cerebrovascular Circulation; Cocaine; Cocaine-Related Disorders; Crack Cocaine; Hemi

2013
In brief: nimodipine oral solution (Nymalize).
    The Medical letter on drugs and therapeutics, 2013, Aug-19, Volume: 55, Issue:1423

    Topics: Administration, Oral; Aneurysm, Ruptured; Calcium Channel Blockers; Drug Approval; Humans; Intracran

2013
Partly reversible central auditory dysfunction induced by cerebral vasospasm after subarachnoid hemorrhage.
    Journal of neurosurgery, 2013, Volume: 119, Issue:5

    Topics: Angioplasty; Auditory Diseases, Central; Female; Humans; Middle Aged; Middle Cerebral Artery; Nimodi

2013
Using nimodipine for patients with aneurysmal subarachnoid hemorrhage.
    Nursing, 2014, Volume: 44, Issue:1

    Topics: Calcium Channel Blockers; Humans; Intracranial Aneurysm; Nimodipine; Practice Guidelines as Topic; R

2014
Diffuse cerebral vasospasm following resection of a hypoglossal schwannoma in a child.
    British journal of neurosurgery, 2014, Volume: 28, Issue:4

    Topics: Cerebral Angiography; Child; Cranial Nerve Neoplasms; Female; Humans; Milrinone; Neurilemmoma; Nimod

2014
New daily persistent headache with a thunderclap headache onset and complete response to nimodipine (a new distinct subtype of NDPH).
    The journal of headache and pain, 2013, Dec-23, Volume: 14

    Topics: Analgesics; Brain; Headache; Humans; Nimodipine; Vasospasm, Intracranial

2013
The need for development of protocol for managing refractory cerebral vasospasm.
    Journal of neurosurgical anesthesiology, 2014, Volume: 26, Issue:3

    Topics: Female; Humans; Milrinone; Nimodipine; Vasodilator Agents; Vasospasm, Intracranial

2014
Protocol for vasospasm.
    Journal of neurosurgical anesthesiology, 2014, Volume: 26, Issue:3

    Topics: Blood Pressure; Clinical Protocols; Humans; Neurosurgical Procedures; Nimodipine; Vasodilator Agents

2014
Continuous selective intra-arterial application of nimodipine in refractory cerebral vasospasm due to aneurysmal subarachnoid hemorrhage.
    BioMed research international, 2014, Volume: 2014

    Topics: Adult; Aged; Cerebrovascular Circulation; Female; Glasgow Outcome Scale; Humans; Infusions, Intra-Ar

2014
Accuracy of nimodipine gel extraction.
    Neurocritical care, 2015, Volume: 22, Issue:1

    Topics: Brain Ischemia; Calcium Channel Blockers; Drug Compounding; Humans; Nimodipine; Vasospasm, Intracran

2015
Repeated combined endovascular therapy with milrinone and nimodipine for the treatment of severe vasospasm: preliminary results.
    Acta neurochirurgica. Supplement, 2015, Volume: 120

    Topics: Adult; Combined Modality Therapy; Endovascular Procedures; Female; Follow-Up Studies; Humans; Male;

2015
Nimodipine for the prevention of cerebral vasospasm after subarachnoid hemorrhage in 12 children.
    Pediatric neurology, 2015, Volume: 52, Issue:3

    Topics: Adolescent; Cerebral Angiography; Child; Child, Preschool; Female; Humans; Male; Nimodipine; Retrosp

2015
Results of an International Survey on the Investigation and Endovascular Management of Cerebral Vasospasm and Delayed Cerebral Ischemia.
    World neurosurgery, 2015, Volume: 83, Issue:6

    Topics: Adult; Australasia; Brain Ischemia; Disease Management; Endovascular Procedures; Europe; Female; Hea

2015
Intracranial biodegradable silica-based nimodipine drug release implant for treating vasospasm in subarachnoid hemorrhage in an experimental healthy pig and dog model.
    BioMed research international, 2015, Volume: 2015

    Topics: Animals; Delayed-Action Preparations; Disease Models, Animal; Dogs; Intracranial Aneurysm; Nimodipin

2015
Molsidomine for the prevention of vasospasm-related delayed ischemic neurological deficits and delayed brain infarction and the improvement of clinical outcome after subarachnoid hemorrhage: a single-center clinical observational study.
    Journal of neurosurgery, 2016, Volume: 124, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Infarction; Brain Ischemia; Drug Therapy, Combinat

2016
Pharmacokinetic Modeling of Intra-arterial Nimodipine Therapy for Subarachnoid Hemorrhage-Related Cerebral Vasospasm.
    Clinical neuroradiology, 2017, Volume: 27, Issue:2

    Topics: Computer Simulation; Humans; Injections, Intra-Arterial; Metabolic Clearance Rate; Models, Cardiovas

2017
Continuous intra-arterial nimodipine infusion in patients with severe refractory cerebral vasospasm after aneurysmal subarachnoid hemorrhage: a feasibility study and outcome results.
    Acta neurochirurgica, 2015, Volume: 157, Issue:12

    Topics: Adult; Calcium Channel Blockers; Female; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nimod

2015
Cannabis, serotonergic drug use and stroke in a 50-year-old woman.
    Internal medicine journal, 2015, Volume: 45, Issue:12

    Topics: Cannabis; Cerebral Angiography; Cognition Disorders; Female; Headache Disorders, Primary; Humans; Ma

2015
Nimodipine Dose Reductions in the Treatment of Patients with Aneurysmal Subarachnoid Hemorrhage.
    Neurocritical care, 2016, Volume: 25, Issue:1

    Topics: Adult; Calcium Channel Blockers; Cerebral Infarction; Female; Humans; Intracranial Aneurysm; Male; M

2016
Real-Time, In Vivo Monitoring, and Quantitative Assessment of Intra-Arterial Vasospasm Therapy.
    Neurocritical care, 2016, Volume: 25, Issue:1

    Topics: Adult; Angiography, Digital Subtraction; Cerebrovascular Circulation; Female; Humans; Infusions, Int

2016
Intra-arterial nimodipine for cerebral vasospasm after subarachnoid haemorrhage: Influence on clinical course and predictors of clinical outcome.
    The neuroradiology journal, 2016, Volume: 29, Issue:1

    Topics: Female; Humans; Injections, Intra-Arterial; Male; Middle Aged; Nimodipine; Prognosis; Radiography; R

2016
Is intra arterial nimodipine really beneficial in vasospasm following aneurysmal subarachnoid haemorrhage?
    British journal of neurosurgery, 2016, Volume: 30, Issue:4

    Topics: Adult; Aged; Female; Humans; Infusions, Intra-Arterial; Intracranial Aneurysm; Male; Middle Aged; Ni

2016
Endovascular therapy for vasospasm after aneurysmatic subarachnoid hemorrhage.
    British journal of neurosurgery, 2016, Volume: 30, Issue:5

    Topics: Adult; Aged; Angioplasty, Balloon; Cerebral Arteries; Endovascular Procedures; Female; Humans; Injec

2016
Retinal Vessel Analysis (RVA) in the Context of Subarachnoid Hemorrhage - A Proof of Concept Study.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: Adult; Aged; Aneurysm; Brain Ischemia; Case-Control Studies; Cerebrovascular Circulation; Female; Hu

2016
Comparison of the Effects and Mechanism of the Curcumin with Different Drugs in Experimental Vasospasm After Subarachnoid Hemorrhage.
    Turkish neurosurgery, 2017, Volume: 27, Issue:6

    Topics: Animals; Apoptosis; Basilar Artery; Cerebellum; Cerebral Cortex; Curcumin; Interleukin-1beta; Interl

2017
Reversible Cerebral Vasoconstriction Syndrome.
    The Journal of the Association of Physicians of India, 2016, Volume: 64, Issue:6

    Topics: Adult; Brain Infarction; Circle of Willis; Coronary Vasospasm; Female; Headache Disorders, Primary;

2016
Clinical Course and Monitoring Parameters After Continuous Interventional Intra-Arterial Treatment in Patients with Refractory Cerebral Vasospasm.
    World neurosurgery, 2017, Volume: 100

    Topics: Cerebral Angiography; Chronic Disease; Disease Progression; Echoencephalography; Female; Humans; Inf

2017
Chemical angioplasty with spasmolytics for vasospasm after subarachnoid hemorrhage.
    Acta neurochirurgica, 2017, Volume: 159, Issue:4

    Topics: Adult; Angioplasty; Female; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nimodipine; Subara

2017
Effect of Intra-Arterial and Intravenous Nimodipine Therapy of Cerebral Vasospasm After Subarachnoid Hemorrhage on Cerebrovascular Reactivity and Oxygenation.
    World neurosurgery, 2017, Volume: 101

    Topics: Adult; Aged; Cerebrovascular Circulation; Female; Homeostasis; Humans; Infusions, Intra-Arterial; In

2017
Letter by Rustemi Regarding Article, "Randomized, Open-Label, Phase 1/2a Study to Determine the Maximum Tolerated Dose of Intraventricular Sustained Release Nimodipine for Subarachnoid Hemorrhage (NEWTON [Nimodipine Microparticles to Enhance Recovery Whil
    Stroke, 2017, Volume: 48, Issue:4

    Topics: Delayed-Action Preparations; Humans; Maximum Tolerated Dose; Nimodipine; Subarachnoid Hemorrhage; Va

2017
Response by Hänggi and Macdonald to Letter Regarding Article, "Randomized, Open-Label, Phase 1/2a Study to Determine the Maximum Tolerated Dose of Intraventricular Sustained Release Nimodipine for Subarachnoid Hemorrhage (NEWTON [Nimodipine Microparticles
    Stroke, 2017, Volume: 48, Issue:4

    Topics: Delayed-Action Preparations; Humans; Maximum Tolerated Dose; Nimodipine; Subarachnoid Hemorrhage; Va

2017
Feasibility and safety of intrathecal nimodipine on posthaemorrhagic cerebral vasospasm refractory to medical and endovascular therapy.
    Clinical neurology and neurosurgery, 2008, Volume: 110, Issue:8

    Topics: Adult; Angiography, Digital Subtraction; Calcium Channel Blockers; Cerebral Angiography; Cerebral In

2008
Nimodipine: test your drug IQ.
    Nursing, 2008, Volume: 38, Issue:7

    Topics: Adult; Calcium Channel Blockers; Drug Interactions; Humans; Nimodipine; Patient Education as Topic;

2008
Intra-arterial nimodipine to treat symptomatic cerebral vasospasm following traumatic subarachnoid haemorrhage. Technical case report.
    Acta neurochirurgica, 2008, Volume: 150, Issue:11

    Topics: Brain Infarction; Cerebral Angiography; Cerebral Arteries; Head Injuries, Closed; Humans; Injections

2008
Effects of dose-response of topical administration of nimodipine on cerebral vasospasm after subarachnoid hemorrhage in rabbits.
    The American journal of the medical sciences, 2009, Volume: 337, Issue:2

    Topics: Administration, Topical; Animals; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Dis

2009
Reversible cerebral vasoconstriction syndrome: a complicated clinical course treated with intra-arterial application of nimodipine.
    Cephalalgia : an international journal of headache, 2009, Volume: 29, Issue:6

    Topics: Brain; Cerebral Angiography; Female; Headache Disorders, Primary; Humans; Hyperlipidemias; Hypertens

2009
Prostacyclin treatment normalises the MCA flow velocity in nimodipine-resistant cerebral vasospasm after aneurysmal subarachnoid haemorrhage: a pilot study.
    Acta neurochirurgica, 2009, Volume: 151, Issue:6

    Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Cerebral Arteries; Cerebrovascular Circula

2009
Headache and visual symptoms in two patients with MRI alterations in posterior cerebral artery territory.
    La Clinica terapeutica, 2009, Volume: 160, Issue:2

    Topics: Acute Disease; Adult; Aged; Anticoagulants; Clopidogrel; Diagnosis, Differential; Diffusion Magnetic

2009
Dose-related efficacy of a continuous intracisternal nimodipine treatment on cerebral vasospasm in the rat double subarachnoid hemorrhage model.
    Neurosurgery, 2009, Volume: 64, Issue:6

    Topics: Animals; Antihypertensive Agents; Cerebral Angiography; Dose-Response Relationship, Drug; Drug Conta

2009
Effects of topical administration of nimodipine on cerebral blood flow following subarachnoid hemorrhage in pigs.
    Journal of neurotrauma, 2013, Apr-01, Volume: 30, Issue:7

    Topics: Administration, Topical; Animals; Brain; Cerebrovascular Circulation; Disease Models, Animal; Male;

2013
[Effects of human urinary tissue kallikreins on vasodilation of basilar artery in rabbits with symptomatic cerebral vasospasm].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2009, May-01, Volume: 47, Issue:9

    Topics: Animals; Disease Models, Animal; Female; Humans; Male; Nimodipine; Rabbits; Random Allocation; Tissu

2009
The effects of intravenous cilostazol and nimodipine on cerebral vasospasm after subarachnoid hemorrhage in an experimental rabbit model.
    Turkish neurosurgery, 2009, Volume: 19, Issue:4

    Topics: Animals; Basilar Artery; Cilostazol; Disease Models, Animal; Drug Therapy, Combination; Injections,

2009
Continuous selective intraarterial infusion of nimodipine for therapy of refractory cerebral vasospasm.
    Neurocritical care, 2010, Volume: 12, Issue:3

    Topics: Adult; Anticoagulants; Calcium Channel Blockers; Cerebral Angiography; Drug Therapy, Combination; Em

2010
Cerebral malaria: a vasculopathy.
    The American journal of pathology, 2010, Volume: 176, Issue:3

    Topics: Animals; Artemether; Artemisinins; Humans; Malaria, Cerebral; Mice; Nimodipine; Plasmodium berghei;

2010
Murine cerebral malaria is associated with a vasospasm-like microcirculatory dysfunction, and survival upon rescue treatment is markedly increased by nimodipine.
    The American journal of pathology, 2010, Volume: 176, Issue:3

    Topics: Animals; Artemether; Artemisinins; Arterioles; Body Temperature; Cell Adhesion; Cerebrovascular Circ

2010
Effects of ebselen versus nimodipine on cerebral vasospasm subsequent to experimental subarachnoid hemorrhage in rats.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010, Volume: 17, Issue:5

    Topics: Analysis of Variance; Animals; Antioxidants; Azoles; Brain; Drug Administration Schedule; Female; In

2010
Acute vasospasm following transcallosal resection of a xanthogranulomatous colloid cyst of the 3rd ventricle.
    Clinical neurology and neurosurgery, 2010, Volume: 112, Issue:6

    Topics: Angioplasty; Calcium Channel Blockers; Central Nervous System Cysts; Cerebral Angiography; Cerebral

2010
Packed red blood cell age does not impact adverse events or outcomes after subarachnoid haemorrhage.
    Transfusion medicine (Oxford, England), 2011, Volume: 21, Issue:2

    Topics: Adult; Aged; Blood Preservation; Cerebral Infarction; Coma; Erythrocyte Aging; Erythrocyte Transfusi

2011
Comparison of nimodipine delivery routes in cerebral vasospasm after subarachnoid hemorrhage: an experimental study in rabbits.
    Acta neurochirurgica. Supplement, 2011, Volume: 110, Issue:Pt 2

    Topics: Administration, Oral; Analysis of Variance; Angiography, Digital Subtraction; Animals; Basilar Arter

2011
Comparison of intrathecal dotarizine and nimodipine treatments in cerebral vasospasm after subarachnoid hemorrhage: an experimental study in rabbits.
    Acta neurochirurgica. Supplement, 2011, Volume: 110, Issue:Pt 2

    Topics: Angiography, Digital Subtraction; Animals; Basilar Artery; Benzhydryl Compounds; Calcium Channel Blo

2011
Comparison of intrathecal flunarizine and nimodipine treatments in cerebral vasospasm after experimental subarachnoid hemorrhage in rabbits.
    Acta neurochirurgica. Supplement, 2011, Volume: 110, Issue:Pt 2

    Topics: Angiography, Digital Subtraction; Animals; Basilar Artery; Calcium Channel Blockers; Disease Models,

2011
The effects of intrathecal nicergoline and nimodipine in cerebral vasospasm: an experimental study in rabbits.
    Acta neurochirurgica. Supplement, 2011, Volume: 110, Issue:Pt 2

    Topics: Adrenergic alpha-Antagonists; Angiography, Digital Subtraction; Animals; Basilar Artery; Calcium Cha

2011
[Changes of nitric oxide and endothelin-1 levels in rat brain tissue during cerebral vasospasm following subarachnoid hemorrhage and protective effect of nimodipine].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2001, Volume: 17, Issue:3

    Topics: Animals; Brain; Cerebrovascular Circulation; Disease Models, Animal; Endothelin-1; Nimodipine; Nitri

2001
Intra-arterial application of nimodipine in reversible cerebral vasoconstriction syndrome: a diagnostic tool in select cases?
    Cephalalgia : an international journal of headache, 2011, Volume: 31, Issue:10

    Topics: Adult; Angiography, Digital Subtraction; Diagnosis, Differential; Female; Humans; Image Interpretati

2011
Continuous local intra-arterial nimodipine administration in severe symptomatic vasospasm after subarachnoid hemorrhage.
    Neurosurgery, 2011, Volume: 68, Issue:6

    Topics: Adult; Cerebral Angiography; Cerebrovascular Circulation; Female; Humans; Infusions, Intra-Arterial;

2011
Activation of vascular KCNQ (Kv7) potassium channels reverses spasmogen-induced constrictor responses in rat basilar artery.
    British journal of pharmacology, 2011, Volume: 164, Issue:2

    Topics: Animals; Basilar Artery; Celecoxib; Electrophysiology; Gene Expression Regulation; KCNQ Potassium Ch

2011
[Effects of nimodipine on rabbits with symptomatic cerebral vasospasm].
    Zhonghua yi xue za zhi, 2011, Feb-01, Volume: 91, Issue:5

    Topics: Animals; Basilar Artery; Disease Models, Animal; Nimodipine; Rabbits; Vasodilator Agents; Vasospasm,

2011
Letter to the editor re Mani et al.
    British journal of pharmacology, 2011, Volume: 164, Issue:2

    Topics: Animals; Celecoxib; KCNQ Potassium Channels; Male; Nimodipine; Pyrazoles; Sulfonamides; Vasoconstric

2011
Endovascular treatment of severe vasospasm in nonaneurysmal perimesencephalic subarachnoid hemorrhage.
    Neurocritical care, 2011, Volume: 15, Issue:3

    Topics: Adult; Angiography, Digital Subtraction; Angioplasty, Balloon; Blood Flow Velocity; Calcium Channel

2011
Resistant vasospasm in subarachnoid hemorrhage treated with continuous intraarterial nimodipine infusion.
    Acta neurochirurgica. Supplement, 2011, Volume: 112

    Topics: Calcium Channel Blockers; Cerebral Angiography; Humans; Infusions, Intra-Arterial; Nimodipine; Retro

2011
Intra-arterial nimodipine infusion for cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
    Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2011, Volume: 17, Issue:2

    Topics: Adult; Calcium Channel Blockers; Cerebral Angiography; Female; Follow-Up Studies; Humans; Infusions,

2011
Thunderclap headache triggered by micturition: responsive to nimodipine.
    The journal of headache and pain, 2011, Volume: 12, Issue:6

    Topics: Antihypertensive Agents; Female; Headache Disorders, Primary; Humans; Hypertension; Middle Aged; Nim

2011
Effect of intraarterial papaverine or nimodipine on vessel diameter in patients with cerebral vasospasm after subarachnoid hemorrhage.
    British journal of neurosurgery, 2012, Volume: 26, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Brain Ischemia; Capillaries; Carotid Artery, I

2012
Puerpera with dyspnoea and epileptic seizure.
    Neurologia (Barcelona, Spain), 2013, Volume: 28, Issue:5

    Topics: Adult; Calcium Channel Blockers; Cerebrovascular Disorders; Coronary Angiography; Dyspnea; Epilepsy;

2013
Cisternal sustained release dihydropyridines for subarachnoid hemorrhage.
    Current neurovascular research, 2012, Volume: 9, Issue:2

    Topics: Animals; Delayed-Action Preparations; Dihydropyridines; Disease Models, Animal; Dogs; Female; Macaca

2012
Nimodipine attenuation of early brain dysfunctions is partially related to its inverting acute vasospasm in a cisterna magna subarachnoid hemorrhage (SAH) model in rats.
    The International journal of neuroscience, 2012, Volume: 122, Issue:10

    Topics: Animals; Blood-Brain Barrier; Cerebrovascular Circulation; Cisterna Magna; Disease Models, Animal; M

2012
Dose-response relationship of locally applied nimodipine in an ex vivo model of cerebral vasospasm.
    Neuroradiology, 2013, Volume: 55, Issue:1

    Topics: Animals; Cerebral Arteries; Dose-Response Relationship, Drug; Male; Nimodipine; Rats; Rats, Wistar;

2013
Endovascular treatment: balloon angioplasty versus nimodipine intra-arterial for medically refractory cerebral vasospasm following aneurysmal subarachnoid hemorrhage.
    Vascular and endovascular surgery, 2012, Volume: 46, Issue:6

    Topics: Adult; Angiography, Digital Subtraction; Angioplasty, Balloon; Chi-Square Distribution; Female; Huma

2012
Reversible cerebral vasoconstriction syndrome: treatment with multiple sessions of intra-arterial nimodipine and angioplasty.
    Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2012, Volume: 18, Issue:3

    Topics: Angioplasty, Balloon; Cerebral Angiography; Combined Modality Therapy; Diagnosis, Differential; Fema

2012
Local delivery of nimodipine by prolonged-release microparticles-feasibility, effectiveness and dose-finding in experimental subarachnoid hemorrhage.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Angiography, Digital Subtraction; Animals; Brain; Calcium-Binding Proteins; Delayed-Action Preparati

2012
Acupuncture for cerebral vasospasm after subarachnoid hemorrhage: a retrospective case-control study.
    Journal of alternative and complementary medicine (New York, N.Y.), 2013, Volume: 19, Issue:5

    Topics: Acupuncture Therapy; Adult; Aged; Aneurysm, Ruptured; Case-Control Studies; Cerebral Angiography; Co

2013
Surgical treatment of ruptured anterior circulation aneurysms: comparison of pterional and supraorbital keyhole approaches.
    Neurosurgery, 2013, Volume: 72, Issue:3

    Topics: Anesthesia, General; Aneurysm, Ruptured; Calcium Channel Blockers; Female; Glasgow Outcome Scale; Hu

2013
In situ forming nimodipine depot system based on microparticles for the treatment of posthemorrhagic cerebral vasospasm.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2013, Volume: 84, Issue:1

    Topics: Delayed-Action Preparations; Microspheres; Nimodipine; Subarachnoid Hemorrhage; Treatment Outcome; V

2013
Reversible segmental cerebral vasoconstriction (Call-Fleming syndrome): are calcium channel inhibitors a potential treatment option?
    Cephalalgia : an international journal of headache, 2003, Volume: 23, Issue:3

    Topics: Calcium Channel Blockers; Cerebral Angiography; Constriction, Pathologic; Female; Humans; Magnetic R

2003
Bathing headache: a variant of idiopathic thunderclap headache.
    Cephalalgia : an international journal of headache, 2003, Volume: 23, Issue:9

    Topics: Adult; Baths; Brain Infarction; Cerebellar Diseases; Cerebellum; Cerebral Arteries; Female; Headache

2003
[Cerebral vasospasms with hemodynamic infarctions as a complication of HELLP syndrome].
    Der Nervenarzt, 2003, Volume: 74, Issue:12

    Topics: Adult; Cesarean Section; Diagnostic Imaging; Dose-Response Relationship, Drug; Female; Follow-Up Stu

2003
The pharmacologic treatment of vasospasm after subarachnoid hemorrhage: a case study.
    The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, 2003, Volume: 35, Issue:6

    Topics: Adult; Blood Pressure; Brain; Cardiotonic Agents; Dobutamine; Female; Fluid Therapy; Hemodilution; H

2003
Efficacy of intra-arterial nimodipine in the treatment of cerebral vasospasm complicating subarachnoid haemorrhage.
    Clinical radiology, 2005, Volume: 60, Issue:9

    Topics: Adult; Aged; Blood Pressure; Cerebral Angiography; Female; Heart Rate; Humans; Infusions, Intra-Arte

2005
Clinical experience of selective intra-arterial nimodipine treatment for cerebral vasospasm following subarachnoid hemorrhage.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:3

    Topics: Calcium Channel Blockers; Humans; Infusions, Intra-Arterial; Nimodipine; Subarachnoid Hemorrhage; Va

2006
Dynamic CT perfusion imaging in subarachnoid hemorrhage-related vasospasm.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:3

    Topics: Angiography; Animals; Cerebrovascular Circulation; Nimodipine; Rabbits; Subarachnoid Hemorrhage; Tom

2006
[Idiopathic thunderclap headache: reversible vasospasm of the Arteria basilaris].
    Der Nervenarzt, 2006, Volume: 77, Issue:10

    Topics: Adult; Angiography, Digital Subtraction; Cerebral Angiography; Diagnosis, Differential; Headache Dis

2006
Dissociation between vasospasm and functional improvement in a murine model of subarachnoid hemorrhage.
    Neurosurgical focus, 2006, Sep-15, Volume: 21, Issue:3

    Topics: Animals; Antihypertensive Agents; Apolipoproteins E; Behavior, Animal; Calcium Channel Blockers; Dis

2006
Intravenous magnesium versus nimodipine in the treatment of patients with aneurysmal subarachnoid hemorrhage: a randomized study.
    Neurosurgery, 2006, Volume: 59, Issue:5

    Topics: Adult; Aged; Brain Ischemia; Calcium Channel Blockers; Cerebral Angiography; Cerebral Infarction; Fe

2006
Symptomatic intracranial stenosis: cerebrovascular complications from elective stent placement.
    Radiology, 2007, Volume: 243, Issue:1

    Topics: Adolescent; Adult; Aged; Angioplasty, Balloon; Cerebral Hemorrhage; Female; Humans; Intracranial Art

2007
Nimodipine loaded PLGA nanoparticles: formulation optimization using factorial design, characterization and in vitro evaluation.
    Current drug delivery, 2007, Volume: 4, Issue:3

    Topics: Calcium Channel Blockers; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Delayed-Act

2007
[Systemic treatments of the vasospasm].
    Annales francaises d'anesthesie et de reanimation, 2007, Volume: 26, Issue:11

    Topics: Hemodilution; Hemodynamics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hy

2007
[Endovascular treatment of vasospasm following subarachnoid aneurysmal haemorrhage].
    Annales francaises d'anesthesie et de reanimation, 2007, Volume: 26, Issue:11

    Topics: Calcium Channel Blockers; Humans; Intracranial Aneurysm; Nicardipine; Nimodipine; Nitroprusside; Pap

2007
Continuous intra-arterial infusion of nimodipine during embolization of cerebral aneurysms associated with vasospasm.
    AJNR. American journal of neuroradiology, 2008, Volume: 29, Issue:2

    Topics: Adult; Aged; Chemotherapy, Adjuvant; Embolization, Therapeutic; Female; Humans; Infusions, Intra-Art

2008
Prevention of delayed cerebral vasospasm by continuous intrathecal infusion of glyceroltrinitrate and nimodipine in the rabbit model in vivo.
    Intensive care medicine, 2008, Volume: 34, Issue:5

    Topics: Animals; Basilar Artery; Cerebral Angiography; Female; Injections, Spinal; Male; Nimodipine; Nitric

2008
Can changes in BIS provide clue to lower limit of cerebral autoregulation?
    Journal of neurosurgical anesthesiology, 2008, Volume: 20, Issue:2

    Topics: Adrenergic alpha-Agonists; Anesthesia, General; Antihypertensive Agents; Blood Pressure; Cerebrovasc

2008
Contemporary management of subarachnoid hemorrhage and vasospasm: the UIC experience.
    Surgical neurology, 2001, Volume: 56, Issue:3

    Topics: Algorithms; Angioplasty, Balloon; Calcium Channel Blockers; Catheterization; Cerebral Angiography; D

2001