nimodipine has been researched along with Aneurysm, Anterior Cerebral Artery in 160 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The prophylactic use of nimodipine in patients with aneurysmal subarachnoid hemorrhage reduces the risk of ischemic brain damage." | 9.12 | Intravenous magnesium versus nimodipine in the treatment of patients with aneurysmal subarachnoid hemorrhage: a randomized study. ( Briegel, J; Kunz, M; Prueckner, S; Schmid-Elsaesser, R; Steiger, HJ; Zausinger, S, 2006) |
| "Nimodipine has been shown to improve neurological outcome after subarachnoid hemorrhage (SAH); the mechanism of this improvement, however, is uncertain." | 9.11 | The effect of nimodipine on cerebral oxygenation in patients with poor-grade subarachnoid hemorrhage. ( Abrahams, JM; Bloom, S; Grady, MS; Heuer, GG; LeRoux, PD; Maloney-Wilensky, E; Smith, MJ; Stiefel, MF, 2004) |
| "Thirty consecutive patients under-going intracranial aneurysmal surgery were prospectively randomized into two groups: Isoflurane (group A, n = 15) and nimodipine (group B, n = 15)." | 9.11 | [The effect of intraoperative continuous nimodipine infusion on cerebral vasospasm during intracranial aneurysm surgery]. ( Han, RQ; Li, SR; Liu, W; Wang, BG; Wang, EZ; Wang, S; Zhao, JZ, 2004) |
| "To assess the cost-effectiveness ratio of nimodipine administration after aneurysmal subarachnoid hemorrhage (SAH) and surgery." | 9.09 | Cost-effectiveness analysis of nimodipine treatment after aneurysmal subarachnoid hemorrhage and surgery. ( Karinen, P; Koivukangas, J; Koivukangas, P; Ohinmaa, A; Ohman, J, 1999) |
| "Nimodipine, a calcium channel blocking drug, is used in the treatment of cerebral arterial spasm after subarachnoid haemorrhage due to bleeding from an intracranial aneurysm." | 9.09 | The effects of nimodipine on vecuronium-induced neuromuscular blockade. ( Aysel, I; Balcioglu, T; Hepaguşlar, H; Uyar, M, 2000) |
| "A total of 213 patients with verified aneurysmal subarachnoid hemorrhage (SAH) of Grades I to III (Hunt and Hess classification) were enrolled in a double-blind placebo-controlled trial to determine the effect of intravenous nimodipine on delayed ischemic deterioration and computerized tomography (CT)-visualized infarcts after SAH and surgery." | 9.07 | Long-term effects of nimodipine on cerebral infarcts and outcome after aneurysmal subarachnoid hemorrhage and surgery. ( Heiskanen, O; Ohman, J; Servo, A, 1991) |
| "We enrolled 75 consecutive patients admitted with subarachnoid hemorrhages in a randomized, double-blind, placebo-controlled trial to determine the effect of early intervention with nimodipine on outcome and cerebral blood flow." | 9.06 | Controlled study of nimodipine in aneurysm patients treated early after subarachnoid hemorrhage. ( Dorrance, D; Lowe, D; Mee, E; Neil-Dwyer, G, 1988) |
| "The effect of intravenous nimodipine on the incidence of mortality and delayed ischemic neurological deficits of patients after aneurysmal subarachnoid hemorrhage (SAH) and surgery was studied in a prospective double-blind placebo-controlled trial." | 9.06 | Effect of nimodipine on the outcome of patients after aneurysmal subarachnoid hemorrhage and surgery. ( Heiskanen, O; Ohman, J, 1988) |
| "Experimental and clinical studies have been performed to investigate the validity of a pharmacological approach to prevent delayed ischemic neurologic deficit from vasospasm after subarachnoid hemorrhage: the calcium channel blocker nimodipine was administered intravenously and perivascularly." | 9.05 | Preventive nimodipine and acute aneurysm surgery. Heading for the control of complications after aneurysmal subarachnoid hemorrhage. ( Auer, LM, 1985) |
| "We enrolled 125 neurologically normal patients with intracranial aneurysms in a multi-institution, prospective, double-blind, randomized, placebo-controlled trial within 96 hours of their subarachnoid hemorrhage, to determine whether treatment with the calcium blocker nimodipine would prevent or reduce the severity of ischemic neurologic deficits from arterial spasm." | 9.05 | Cerebral arterial spasm--a controlled trial of nimodipine in patients with subarachnoid hemorrhage. ( Ahn, HS; Allen, GS; Battye, R; Bertsch, LA; Boisvert, DP; Boone, SC; Chou, SN; Crabbe, RA; Dorsey, FC; Hundley, MB; Ingram, CR; Johnson, RK; Kelly, DL; Lavik, PJ; Mellits, DE; Preziosi, TJ; Rosenbloom, SB; Strom, JA; Transou, CR; Weir, BK, 1983) |
| "Fifty-three percent of patients developed new cerebral infarction after intraarterial nimodipine and additional PTA in selected cases." | 7.91 | Complication rate of intraarterial treatment of severe cerebral vasospasm after subarachnoid hemorrhage with nimodipine and percutaneous transluminal balloon angioplasty: Worth the risk? ( Adami, D; Berkefeld, J; Konczalla, J; Pfeilschifter, W; Platz, J; Wagner, M; Weidauer, S, 2019) |
| "Guidelines for aneurysm subarachnoid hemorrhage (aSAH) management recommend treatment with nimodipine to all patients to reduce delayed cerebral ischemia (DCI) and poor clinical outcome." | 7.88 | Impact of Early Versus Late Intravenous Followed by Oral Nimodipine Treatment on the Occurrence of Delayed Cerebral Ischemia Among Patients With Aneurysm Subarachnoid Hemorrhage. ( Liengudom, A; Samseethong, T; Suansanae, T; Suthisisang, C; Veerasarn, K, 2018) |
| "The incidence of cerebral infarction and poor outcome in patients with aneurysmal subarachnoid hemorrhage (aSAH) is reduced by oral nimodipine but acute effects of the drug may include a significant decrease in mean arterial blood pressure (MAP)." | 7.83 | Nimodipine Dose Reductions in the Treatment of Patients with Aneurysmal Subarachnoid Hemorrhage. ( Diesing, D; Sandow, N; Sarrafzadeh, A; Vajkoczy, P; Wolf, S, 2016) |
| "Oral nimodipine is standard therapy for patients suffering an aneurysmal subarachnoid hemorrhage (aSAH)." | 7.83 | Effects of 14 Versus 21 Days of Nimodipine Therapy on Neurological Outcomes in Aneurysmal Subarachnoid Hemorrhage Patients. ( Bales, J; Cho, S; Joffe, AM; Khandelwal, N; Korab, G; Tran, TK, 2016) |
| "Nimodipine is a widely used medication for treating delayed cerebral ischemia (DCI) after subarachnoid hemorrhage." | 7.81 | Intracranial biodegradable silica-based nimodipine drug release implant for treating vasospasm in subarachnoid hemorrhage in an experimental healthy pig and dog model. ( Ahtola-Sätilä, T; Forsback, AP; Frantzén, J; Koskimäki, J; Laakso, A; Saloranta, L; Simola, O; Tarkia, M, 2015) |
| "Nimodipine therapy has become a standard component of the treatment regimen used in patients with aneurysmal subarachnoid hemorrhage (SAH)." | 7.70 | The efficacy of an abbreviated course of nimodipine in patients with good-grade aneurysmal subarachnoid hemorrhage. ( Toyota, BD, 1999) |
| "The efficacy and tolerability of the dihydropyridine calcium antagonist nimodipine (BAY e 9736) in the prophylaxis of ischemic neurological deficits after subarachnoid hemorrhage were investigated in 171 patients in an open, prospective, multicenter study." | 7.67 | Clinical experience with nimodipine in the prophylaxis of neurological deficits after subarachnoid hemorrhage. ( Adelt, D; Ammerer, HP; Baumann, H; Böker, DK; Grotenhuis, JA; Istaitih, AR; Jaksche, H; Karnick, R; Kazner, E; Sprung, C, 1985) |
| "Eighty-four patients were treated early with nimodipine intravenously, and thereafter orally, up to 21 days after aneurysmal subarachnoid hemorrhage." | 7.67 | Nimodipine treatment of selected good-risk patients with subarachnoid hemorrhage: no significant difference between present and historical results. ( Bolander, H; Carlsson, H; Pellettieri, L; Sjölander, U, 1988) |
| "Intravenous Nimodipine was administered to 109 patients (65 female and 44 male) with either pre- or post-operative progressive neurological deterioration from cerebral vasospasm following subarachnoid hemorrhage from a ruptured aneurysm." | 7.67 | Nimodipine treatment of ischemic neurological deficits due to cerebral vasospasm after subarachnoid hemorrhage. Clinical results of a multicenter study. ( Auer, LM; Böker, DK; Gaab, M; Jaksche, H; Koos, WT; Kostron, H; Meinig, G; Muizelaar, JP; Perneczky, A; van der Werf, AJ, 1985) |
| "In patients with aneurysmal subarachnoid hemorrhage (SAH), delayed ischemic cerebral dysfunction (DID or symptomatic vasospasm) with subsequent fixed neurological dysfunction (FND) is a frequent and most feared complication induced by the hemorrhage." | 6.66 | Cerebral vasospasm and calcium channel blockade. Nimodipine treatment in patients with aneurysmal subarachnoid hemorrhage. ( Andersson, KE; Brandt, L; Ljunggren, B; Säveland, H; Vinge, E, 1986) |
| "Operative interventions in subarachnoid hemorrhages caused by brain vessel aneurysm require meticulous dissection of the latter." | 5.29 | [Controlled hypotension against a background of nimodipine during an operation on neurosurgical patients with hypertension]. ( Karadimov, D, 1995) |
| "Nimodipine treatment was associated with a significant increase of survival (11." | 5.29 | [Comparison of 2 consecutive series of aneurysmal subarachnoid hemorrhage with or without nimodipine and study of the temperature curve]. ( Bazin, A; Bernard, MH; Bertault, R; Gomis, P; Graftieaux, JP; Peruzzi, P; Rousseaux, P; Scherpereel, B, 1993) |
| "Nimodipine was then discontinued and, 48 hours later, when the middle cerebral artery velocity was still in the same range, CO2 vasoreactivity was tested again." | 5.28 | Effect of nimodipine on cerebrovascular response to CO2 in asymptomatic individuals and patients with subarachnoid hemorrhage: a transcranial Doppler ultrasound study. ( Nirkko, AC; Seiler, RW, 1990) |
| "Twenty-four patients with subarachnoid hemorrhage due to rupture of a supratentorial aneurysm underwent surgery within 72 hours after subarachnoid hemorrhage." | 5.27 | Thromboxane B2 levels in serum during continuous administration of nimodipine to patients with aneurysmal subarachnoid hemorrhage. ( Andersson, KE; Brandt, L; Ljunggren, B; Vinge, E, 1988) |
| "The prophylactic use of nimodipine in patients with aneurysmal subarachnoid hemorrhage reduces the risk of ischemic brain damage." | 5.12 | Intravenous magnesium versus nimodipine in the treatment of patients with aneurysmal subarachnoid hemorrhage: a randomized study. ( Briegel, J; Kunz, M; Prueckner, S; Schmid-Elsaesser, R; Steiger, HJ; Zausinger, S, 2006) |
| "Nimodipine has been shown to improve neurological outcome after subarachnoid hemorrhage (SAH); the mechanism of this improvement, however, is uncertain." | 5.11 | The effect of nimodipine on cerebral oxygenation in patients with poor-grade subarachnoid hemorrhage. ( Abrahams, JM; Bloom, S; Grady, MS; Heuer, GG; LeRoux, PD; Maloney-Wilensky, E; Smith, MJ; Stiefel, MF, 2004) |
| "Thirty consecutive patients under-going intracranial aneurysmal surgery were prospectively randomized into two groups: Isoflurane (group A, n = 15) and nimodipine (group B, n = 15)." | 5.11 | [The effect of intraoperative continuous nimodipine infusion on cerebral vasospasm during intracranial aneurysm surgery]. ( Han, RQ; Li, SR; Liu, W; Wang, BG; Wang, EZ; Wang, S; Zhao, JZ, 2004) |
| "Nimodipine, a calcium channel blocking drug, is used in the treatment of cerebral arterial spasm after subarachnoid haemorrhage due to bleeding from an intracranial aneurysm." | 5.09 | The effects of nimodipine on vecuronium-induced neuromuscular blockade. ( Aysel, I; Balcioglu, T; Hepaguşlar, H; Uyar, M, 2000) |
| "To assess the cost-effectiveness ratio of nimodipine administration after aneurysmal subarachnoid hemorrhage (SAH) and surgery." | 5.09 | Cost-effectiveness analysis of nimodipine treatment after aneurysmal subarachnoid hemorrhage and surgery. ( Karinen, P; Koivukangas, J; Koivukangas, P; Ohinmaa, A; Ohman, J, 1999) |
| "A total of 213 patients with verified aneurysmal subarachnoid hemorrhage (SAH) of Grades I to III (Hunt and Hess classification) were enrolled in a double-blind placebo-controlled trial to determine the effect of intravenous nimodipine on delayed ischemic deterioration and computerized tomography (CT)-visualized infarcts after SAH and surgery." | 5.07 | Long-term effects of nimodipine on cerebral infarcts and outcome after aneurysmal subarachnoid hemorrhage and surgery. ( Heiskanen, O; Ohman, J; Servo, A, 1991) |
| "We enrolled 75 consecutive patients admitted with subarachnoid hemorrhages in a randomized, double-blind, placebo-controlled trial to determine the effect of early intervention with nimodipine on outcome and cerebral blood flow." | 5.06 | Controlled study of nimodipine in aneurysm patients treated early after subarachnoid hemorrhage. ( Dorrance, D; Lowe, D; Mee, E; Neil-Dwyer, G, 1988) |
| "The effect of intravenous nimodipine on the incidence of mortality and delayed ischemic neurological deficits of patients after aneurysmal subarachnoid hemorrhage (SAH) and surgery was studied in a prospective double-blind placebo-controlled trial." | 5.06 | Effect of nimodipine on the outcome of patients after aneurysmal subarachnoid hemorrhage and surgery. ( Heiskanen, O; Ohman, J, 1988) |
| "Experimental and clinical studies have been performed to investigate the validity of a pharmacological approach to prevent delayed ischemic neurologic deficit from vasospasm after subarachnoid hemorrhage: the calcium channel blocker nimodipine was administered intravenously and perivascularly." | 5.05 | Preventive nimodipine and acute aneurysm surgery. Heading for the control of complications after aneurysmal subarachnoid hemorrhage. ( Auer, LM, 1985) |
| "We enrolled 125 neurologically normal patients with intracranial aneurysms in a multi-institution, prospective, double-blind, randomized, placebo-controlled trial within 96 hours of their subarachnoid hemorrhage, to determine whether treatment with the calcium blocker nimodipine would prevent or reduce the severity of ischemic neurologic deficits from arterial spasm." | 5.05 | Cerebral arterial spasm--a controlled trial of nimodipine in patients with subarachnoid hemorrhage. ( Ahn, HS; Allen, GS; Battye, R; Bertsch, LA; Boisvert, DP; Boone, SC; Chou, SN; Crabbe, RA; Dorsey, FC; Hundley, MB; Ingram, CR; Johnson, RK; Kelly, DL; Lavik, PJ; Mellits, DE; Preziosi, TJ; Rosenbloom, SB; Strom, JA; Transou, CR; Weir, BK, 1983) |
| " Nimodipine is administered to maintain a euvolemic state and prevent delayed cerebral ischemia (DCI)." | 4.90 | Treatment of subarachnoid hemorrhage. ( Diringer, MN; Raya, AK, 2014) |
| "Fifty-three percent of patients developed new cerebral infarction after intraarterial nimodipine and additional PTA in selected cases." | 3.91 | Complication rate of intraarterial treatment of severe cerebral vasospasm after subarachnoid hemorrhage with nimodipine and percutaneous transluminal balloon angioplasty: Worth the risk? ( Adami, D; Berkefeld, J; Konczalla, J; Pfeilschifter, W; Platz, J; Wagner, M; Weidauer, S, 2019) |
| "Guidelines for aneurysm subarachnoid hemorrhage (aSAH) management recommend treatment with nimodipine to all patients to reduce delayed cerebral ischemia (DCI) and poor clinical outcome." | 3.88 | Impact of Early Versus Late Intravenous Followed by Oral Nimodipine Treatment on the Occurrence of Delayed Cerebral Ischemia Among Patients With Aneurysm Subarachnoid Hemorrhage. ( Liengudom, A; Samseethong, T; Suansanae, T; Suthisisang, C; Veerasarn, K, 2018) |
| "The incidence of cerebral infarction and poor outcome in patients with aneurysmal subarachnoid hemorrhage (aSAH) is reduced by oral nimodipine but acute effects of the drug may include a significant decrease in mean arterial blood pressure (MAP)." | 3.83 | Nimodipine Dose Reductions in the Treatment of Patients with Aneurysmal Subarachnoid Hemorrhage. ( Diesing, D; Sandow, N; Sarrafzadeh, A; Vajkoczy, P; Wolf, S, 2016) |
| "Oral nimodipine is standard therapy for patients suffering an aneurysmal subarachnoid hemorrhage (aSAH)." | 3.83 | Effects of 14 Versus 21 Days of Nimodipine Therapy on Neurological Outcomes in Aneurysmal Subarachnoid Hemorrhage Patients. ( Bales, J; Cho, S; Joffe, AM; Khandelwal, N; Korab, G; Tran, TK, 2016) |
| "Nimodipine is a widely used medication for treating delayed cerebral ischemia (DCI) after subarachnoid hemorrhage." | 3.81 | Intracranial biodegradable silica-based nimodipine drug release implant for treating vasospasm in subarachnoid hemorrhage in an experimental healthy pig and dog model. ( Ahtola-Sätilä, T; Forsback, AP; Frantzén, J; Koskimäki, J; Laakso, A; Saloranta, L; Simola, O; Tarkia, M, 2015) |
| "Between August 2001 and January 2004 we treated nine acute subarachnoid hemorrhage (SAH) patients with a combination of stents and platinum coils." | 3.73 | [Stenting plus coiling: dangerous or helpful?]. ( Dörfler, A; Forsting, M; Gizewski, E; Stolke, D; Wanke, I, 2005) |
| "Nimodipine therapy has become a standard component of the treatment regimen used in patients with aneurysmal subarachnoid hemorrhage (SAH)." | 3.70 | The efficacy of an abbreviated course of nimodipine in patients with good-grade aneurysmal subarachnoid hemorrhage. ( Toyota, BD, 1999) |
| "To determine the incidence of induced systemic hypotension in patients after aneurysmal subarachnoid haemorrhage (SAH) and nimodipine treatment 87 consecutive cases were reviewed." | 3.69 | Hypotensive effect of nimodipine during treatment for aneurysmal subarachnoid haemorrhage. ( Chioléro, R; de Tribolet, N; Porchet, F, 1995) |
| "To prevent and treat the ischemic complications due to the vasospasm, this report suggest the management of aneurysmal subarachnoid haemorrhage by the association of antifibrinolytics (tranexamic acid) to lower the risk of rebleeding, calcium channel blockers (nimodipine), and the keeping of an effective total blood volume (thanks to volume expansion and dopamine)." | 3.68 | [Evaluation of the treatment of aneurysmal meningeal hemorrhage with antifibrinolytic agents, calcium inhibitors and maintenance of effective blood volume]. ( Berard, JP; Cavaroc, G; Greil, P; Gutknecht, JL; Halberstadt, J; Irthum, B; Planchon, E, 1990) |
| "During recent years, the management of subarachnoid hemorrhage (SAH) has changed, resulting in an increase in early operations and routine administration of nimodipine." | 3.68 | Cerebral hemodynamics in subarachnoid hemorrhage evaluated by transcranial Doppler sonography. Part 1. Reliability of flow velocities in clinical management. ( Fahlbusch, R; Gönner, F; Laumer, R; Priem, R; Steinmeier, R; Vogtmann, T, 1993) |
| "The study evaluated the effectiveness of the combination of nimodipine and cyclosporine A vs nimodipine alone in the prevention of delayed neurologic deficit in 82 (31 plus 51) patients in whom intracranial aneurysms were clipped within 72 h after subarachnoid haemorrhage." | 3.68 | A strategy for analyzing multiple parameters with application to aneurysmal SAH patients all of them clipped but treated with and without cyclosporine. ( Andrychowski, J; Barczewska, M; Bojarski, P; Dziewiecki, C; Pastuszko, M; Ryba, M, 1993) |
| "We studied adenosine diphosphate-induced platelet aggregation and the associated release of thromboxane B2 in 49 patients with subarachnoid hemorrhage in relation to angiographic vasospasm." | 3.68 | Angiographic vasospasm and release of platelet thromboxane after subarachnoid hemorrhage. ( Heiskanen, O; Juvela, S; Kaste, M; Ohman, J; Servo, A, 1991) |
| "Eighty-four patients were treated early with nimodipine intravenously, and thereafter orally, up to 21 days after aneurysmal subarachnoid hemorrhage." | 3.67 | Nimodipine treatment of selected good-risk patients with subarachnoid hemorrhage: no significant difference between present and historical results. ( Bolander, H; Carlsson, H; Pellettieri, L; Sjölander, U, 1988) |
| "During opiate anesthesia (standardized dosage of fentanyl) for operation of cerebral aneurysms after subarachnoid hemorrhage, different hemodynamic, respiratory, metabolic, and endocrine parameters were determined before (1 in Fig." | 3.67 | [Effect of the calcium antagonist nimodipine on hemodynamics, gas exchange and endocrine parameters in opiate anesthesia]. ( Adams, HA; Börner, U; Gips, H; Hempelmann, G; Marck, P; Müller, H; Otto, O, 1987) |
| "The lipophilic calcium antagonist Nimodipine (Bayer Pharma , Wuppertal ) was administered during aneurysm operations in 40 patients with ruptured intracranial aneurysm." | 3.67 | Intraoperative topical nimodipine after aneurysm clipping. ( Auer, LM; Ito, Z; Suzuki, A; Yasui, N, 1984) |
| "Sixty-five patients with ruptured aneurysms were operated upon within 48 to 72 hours after subarachnoid hemorrhage (SAH) and were treated with a regimen of intra- and postoperative nimodipine for the prevention of symptomatic vasospasm." | 3.67 | Acute operation and preventive nimodipine improve outcome in patients with ruptured cerebral aneurysms. ( Auer, LM, 1984) |
| "Fifty four patients (33 male and 21 female, mean age 47) with spontaneous aneurysmal subarachnoid hemorrhages have been tested by repeated TCD: 25 of them were systematically administered intravenous Nimodipine when admitted at hospital, the 29 others constituted a reference group." | 3.67 | [Value of transcranial Doppler in the monitoring of aneurysmal subarachnoid hemorrhage treated with calcium inhibitors]. ( Auque, J; Burdin, D; Ducrocq, X; Girard, A; Hepner, H; Lepoire, J; Marchal, JC; Pincemaille, B, 1989) |
| "A consecutive series of 100 individuals with aneurysmal subarachnoid hemorrhage were subjected to early aneurysm operation followed by subsequent intravenous administration of the calcium antagonist nimodipine during the critical period for symptomatic vasospasm." | 3.67 | Delayed ischemic deterioration in patients with early aneurysm operation and intravenous nimodipine. ( Brandt, L; Ljunggren, B; Messeter, K; Säveland, H, 1986) |
| "The efficacy and tolerability of the dihydropyridine calcium antagonist nimodipine (BAY e 9736) in the prophylaxis of ischemic neurological deficits after subarachnoid hemorrhage were investigated in 171 patients in an open, prospective, multicenter study." | 3.67 | Clinical experience with nimodipine in the prophylaxis of neurological deficits after subarachnoid hemorrhage. ( Adelt, D; Ammerer, HP; Baumann, H; Böker, DK; Grotenhuis, JA; Istaitih, AR; Jaksche, H; Karnick, R; Kazner, E; Sprung, C, 1985) |
| "Intravenous Nimodipine was administered to 109 patients (65 female and 44 male) with either pre- or post-operative progressive neurological deterioration from cerebral vasospasm following subarachnoid hemorrhage from a ruptured aneurysm." | 3.67 | Nimodipine treatment of ischemic neurological deficits due to cerebral vasospasm after subarachnoid hemorrhage. Clinical results of a multicenter study. ( Auer, LM; Böker, DK; Gaab, M; Jaksche, H; Koos, WT; Kostron, H; Meinig, G; Muizelaar, JP; Perneczky, A; van der Werf, AJ, 1985) |
| " Tirilazad mesylate at dosage levels of up to 6 mg/kg per day for 8 to 10 days following SAH did not improve the overall outcome in patients with aneurysmal SAH in this trial." | 2.68 | A randomized, double-blind, vehicle-controlled trial of tirilazad mesylate in patients with aneurysmal subarachnoid hemorrhage: a cooperative study in North America. ( Alves, WM; Apperson-Hansen, C; Haley, EC; Kassell, NF; Maile, MH, 1997) |
| " This treatment regimen was associated with a low incidence of delayed neurological dysfunction with no significant difference between the two dosage groups: three patients (1." | 2.67 | Early aneurysm surgery and preventive therapy with intravenously administered nimodipine: a multicenter, double-blind, dose-comparison study. ( Brandt, L; Conzen, MA; Gilsbach, JM; Ljunggren, B; Mokry, M; Reulen, HJ; von Essen, C; von Holst, H, 1990) |
| "Nimodipine treatment was associated with a significant reduction of delayed ischemic deterioration (all operation group combined, nimodipine vs." | 2.66 | Timing of operation for ruptured supratentorial aneurysms: a prospective randomized study. ( Heiskanen, O; Ohman, J, 1989) |
| "SAH due to cerebral aneurysm and receiving 21 days of treatment)." | 2.66 | Early intervention with nimodipine in subarachnoid haemorrhage. ( Dorrance, D; Lowe, D; Mee, E; Neil-Dwyer, G, 1987) |
| "In patients with aneurysmal subarachnoid hemorrhage (SAH), delayed ischemic cerebral dysfunction (DID or symptomatic vasospasm) with subsequent fixed neurological dysfunction (FND) is a frequent and most feared complication induced by the hemorrhage." | 2.66 | Cerebral vasospasm and calcium channel blockade. Nimodipine treatment in patients with aneurysmal subarachnoid hemorrhage. ( Andersson, KE; Brandt, L; Ljunggren, B; Säveland, H; Vinge, E, 1986) |
| "Nimodipine treatment was associated with a significantly better outcome (p less than 0." | 2.66 | Nimodipine treatment in poor-grade aneurysm patients. Results of a multicenter double-blind placebo-controlled trial. ( Benoit, BG; Disney, LB; Gentili, F; Grace, M; Holness, RO; Khan, MI; Mohr, G; Petruk, KC; Weir, BK; West, M, 1988) |
| "Early treatment of ruptured aneurysms is advocated; delayed intervention complicates the treatment strategy leading to significant vasospasm and poor prognosis." | 2.58 | Coadjuvant Treatment of Vasospasm in Ruptured Unsecured Cerebral Aneurysms with Aggressive Angioplasty, Intra-Arterial Nimodipine, and Aneurysm Embolization. ( Chen, CC; Chen, CT; Hsieh, PC; Yi-Chou Wang, A, 2018) |
| "Outcome of patients with aneurysmal subarachnoid hemorrhage (SAH) has improved over the last decades." | 2.49 | SAHIT Investigators--on the outcome of some subarachnoid hemorrhage clinical trials. ( Cusimano, MD; Etminan, N; Hanggi, D; Hasan, D; Ilodigwe, D; Jaja, B; Lantigua, H; Le Roux, P; Lo, B; Louffat-Olivares, A; Macdonald, RL; Mayer, S; Molyneux, A; Quinn, A; Schenk, T; Schweizer, TA; Singh, J; Spears, J; Todd, M; Torner, J; Vergouwen, MD; Wong, GK, 2013) |
| "This process, known as cerebral vasospasm, is the most common cause of DCI after SAH." | 2.48 | Management of delayed cerebral ischemia after subarachnoid hemorrhage. ( Koenig, MA, 2012) |
| "Nimodipine infusion was started before surgery (1 mg/Kg/h)." | 2.38 | [Vasospasm, early surgery and nimodipine. A series of 120 consecutive cases of surgically treated ruptured aneurysm]. ( Creissard, P; Freger, P; Langlois, O; Proust, F; Rabehenoina, C; Tadie, M, 1992) |
| "Early surgery on cerebral aneurysms is advocated in order to prevent rebleeding and for early removal of blood clot from the basal cisterns." | 2.37 | [Vascular spasm and cerebral ischemia after meningeal hemorrhage caused by rupture of an aneurysm]. ( Van der Werf, AJ, 1986) |
| "The current management of subarachnoid hemorrhage (SAH) in the urban Chinese population remains unclear and the relevant literature is still lacking." | 1.91 | Current management of subarachnoid hemorrhage in a northern urban Chinese population: a multi-center surveillance study. ( Cheng, GJ; Li, RM; Lv, L; Ma, N; Zhang, JF; Zhang, L; Zhang, WS, 2023) |
| "Background and Purpose- Delayed cerebral infarction (DCI) is an important cause of morbidity and mortality in patients with aneurysmal subarachnoid hemorrhage (aSAH)." | 1.56 | Impact of Stereotactic Ventriculocisternostomy on Delayed Cerebral Infarction and Outcome After Subarachnoid Hemorrhage. ( Bardutzky, J; Beck, J; Buttler, J; Coenen, VA; Csok, I; Egger, K; Grauvogel, J; Niesen, WD; Reinacher, PC; Roelz, R; Rohr, E; Sajonz, B; Schaefer, JH; Scheiwe, C; Shah, MJ; Steiert, C, 2020) |
| "Twenty (20) patients with SAH were treated after their ruptured aneurysms had been secured." | 1.39 | Acupuncture for cerebral vasospasm after subarachnoid hemorrhage: a retrospective case-control study. ( Bae, HS; Cho, SY; Kim, GK; Ko, CN; Koh, JS; Lee, IW; Lee, SH; Park, JM; Park, SU, 2013) |
| "To determine if the age of packed red blood cells (PRBCs) is associated with adverse events or outcomes in patients with subarachnoid haemorrhage (SAH)." | 1.37 | Packed red blood cell age does not impact adverse events or outcomes after subarachnoid haemorrhage. ( Ault, ML; Duran, IM; Liebling, SM; Naidech, AM, 2011) |
| "Despite rigorous efforts, cerebral vasospasm remains an important cause of morbidity and mortality in patients who survive their initial subarachnoid hemorrhage." | 1.35 | Continuous intra-arterial infusion of nimodipine during embolization of cerebral aneurysms associated with vasospasm. ( Cinar, C; Oran, I, 2008) |
| "Operative interventions in subarachnoid hemorrhages caused by brain vessel aneurysm require meticulous dissection of the latter." | 1.29 | [Controlled hypotension against a background of nimodipine during an operation on neurosurgical patients with hypertension]. ( Karadimov, D, 1995) |
| "Nimodipine treatment was started within three days of delayed ischaemic deficit (DID) onset, at a low dose increased quickly to 30-45 ug/kg/hr, and reduced gradually over the last day or two of the course." | 1.29 | Treatment of symptomatic vasospasm with nimodipine. ( Compton, JS; Dorsch, NW, 1993) |
| "Nimodipine infusion was started before surgery." | 1.29 | Causes of morbidity and mortality after ruptured aneurysm surgery in a series of 230 patients. The importance of control angiography. ( Creissard, P; Freger, P; Hannequin, D; Langlois, O; Proust, F, 1995) |
| "Nimodipine was administered in 231 (84%) of the 275 patients." | 1.29 | Which are the major determinants for outcome in aneurysmal subarachnoid hemorrhage? A prospective total management study from a strictly unselected series. ( Brandt, L; Säveland, H, 1994) |
| "As soon as the subarachnoid hemorrhage diagnosis is confirmed by computed tomography (or if unconfirmed, by lumbar puncture), we assume that each patient may have an aneurysm." | 1.29 | Are the calcium antagonists really useful in cerebral aneurysmal surgery? A retrospective study. ( Alhayek, G; Fournier, D; Guy, G; Menei, P; Mercier, P; Rizk, T, 1994) |
| "Early hydrocephalus is a risk factor of shunt-dependent late hydrocephalus (SDHC)." | 1.29 | Shunt-dependent hydrocephalus after subarachnoid haemorrhage and aneurysm surgery: timing of surgery is not a risk factor. ( Hernesniemi, J; Kari, A; Luukkonen, M; Niskanen, M; Puranen, M; Tapaninaho, A; Vapalahti, M, 1993) |
| "Nimodipine treatment was associated with a significant increase of survival (11." | 1.29 | [Comparison of 2 consecutive series of aneurysmal subarachnoid hemorrhage with or without nimodipine and study of the temperature curve]. ( Bazin, A; Bernard, MH; Bertault, R; Gomis, P; Graftieaux, JP; Peruzzi, P; Rousseaux, P; Scherpereel, B, 1993) |
| "Nimodipine was then discontinued and, 48 hours later, when the middle cerebral artery velocity was still in the same range, CO2 vasoreactivity was tested again." | 1.28 | Effect of nimodipine on cerebrovascular response to CO2 in asymptomatic individuals and patients with subarachnoid hemorrhage: a transcranial Doppler ultrasound study. ( Nirkko, AC; Seiler, RW, 1990) |
| "Morbidity after aneurysmal subarachnoid hemorrhages is proceeding from many factors; ischemic etiology is underestimated and frequently thought to be vasospasm related only." | 1.28 | [Does nimodipine improve the outcome of perioperative complications of aneurysm rupture? Results of systematic treatment]. ( Ades, PE; Aesch, B; Buchet, S; Fabre, M; Jan, M; Lamotte, C; Rieant, JF, 1989) |
| "Among the 141 patients with subarachnoid hemorrhage but not intracerebral or intraventricular hematoma, 16 made an unfavorable outcome, ie, 11% versus 56% among patients with intracerebral hematoma/intraventricular hematoma on preoperative computed tomography scan." | 1.28 | Unfavorable outcome following early surgical repair of ruptured cerebral aneurysms--a critical review of 238 patients. ( Auer, LM, 1991) |
| "Nimodipine was administered to 269 of the 325 patients: intravenously in 218, orally in 15, and intravenously followed by orally in 36." | 1.28 | Overall outcome in aneurysmal subarachnoid hemorrhage. A prospective study from neurosurgical units in Sweden during a 1-year period. ( Algers, G; Brandt, L; Edner, G; Hillman, J; Jakobsson, KE; Säveland, H, 1992) |
| "The postoperative intracerebral hemorrhage occurred in 16 cases and seemed to be caused by one or more of the following events: cerebral infarction developed during the preoperative period, occlusion of the cerebral veins during the Sylvian dissection, cerebral retraction and/or sudden change of intracranial hemodynamics." | 1.28 | Surgery of intracranial aneurysms at Yonsei University: 780 cases. ( Lee, KC, 1991) |
| " Mean bioavailability was 15." | 1.27 | Pharmacokinetics of nimodipine in patients with aneurysmal subarachnoid haemorrhage. ( Andersson, KE; Brandt, L; Ljunggren, B; Nilsson, LG; Rosendal-Helgesen, S; Vinge, E, 1986) |
| "Nimodipine was well tolerated and neither significant hypotension nor any other adverse reaction attributable to the drug was observed." | 1.27 | Nimodipine and early aneurysm operation in good condition SAH patients. ( Auer, LM; Brandt, L; Ebeling, U; Gilsbach, J; Groeger, U; Harders, A; Ljunggren, B; Oppel, F; Reulen, HJ; Saeveland, H, 1986) |
| "Twenty-four patients with subarachnoid hemorrhage due to rupture of a supratentorial aneurysm underwent surgery within 72 hours after subarachnoid hemorrhage." | 1.27 | Thromboxane B2 levels in serum during continuous administration of nimodipine to patients with aneurysmal subarachnoid hemorrhage. ( Andersson, KE; Brandt, L; Ljunggren, B; Vinge, E, 1988) |
| "One nimodipine-treated patient with a preserved CO2 response, in whom operation was complicated, developed DID." | 1.27 | Prediction and prevention of delayed ischemic dysfunction after aneurysmal subarachnoid hemorrhage and early operation. ( Algotsson, L; Brandt, L; Ljunggren, B; Messeter, K; Romner, B; Ryding, E; Svendgaard, NA, 1987) |
| "The overall morbidity and mortality from aneurysmal subarachnoid hemorrhage have not changed significantly over the past 30 years in spite of great progress in surgical technology and diagnostic capabilities." | 1.27 | Current management of cerebral aneurysms: is it based on facts or myths? ( Ausman, JI; Diaz, FG; Fielding, AS; Malik, GM; Son, CS, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 60 (37.50) | 18.7374 |
| 1990's | 58 (36.25) | 18.2507 |
| 2000's | 14 (8.75) | 29.6817 |
| 2010's | 23 (14.38) | 24.3611 |
| 2020's | 5 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, JF | 1 |
| Ma, N | 1 |
| Zhang, WS | 1 |
| Cheng, GJ | 1 |
| Lv, L | 1 |
| Zhang, L | 1 |
| Li, RM | 1 |
| Cottenceau, V | 1 |
| Poutier, B | 1 |
| Gariel, F | 1 |
| Sauvage, N | 1 |
| Petit, L | 1 |
| Carrie, C | 1 |
| Biais, M | 1 |
| Roelz, R | 1 |
| Schaefer, JH | 1 |
| Scheiwe, C | 1 |
| Sajonz, B | 1 |
| Csok, I | 1 |
| Steiert, C | 1 |
| Buttler, J | 1 |
| Rohr, E | 1 |
| Grauvogel, J | 1 |
| Shah, MJ | 1 |
| Egger, K | 1 |
| Niesen, WD | 1 |
| Bardutzky, J | 1 |
| Beck, J | 1 |
| Coenen, VA | 1 |
| Reinacher, PC | 1 |
| Chen, CT | 2 |
| Chen, CC | 2 |
| Wang, AY | 1 |
| Wu, YM | 1 |
| Chin, SC | 1 |
| Hsieh, PC | 2 |
| Yeap, MC | 1 |
| Hsu, SY | 1 |
| Lin, YJ | 1 |
| Yu, W | 1 |
| Huang, Y | 1 |
| Zhang, X | 1 |
| Luo, H | 1 |
| Chen, W | 1 |
| Jiang, Y | 1 |
| Cheng, Y | 1 |
| Harbin, M | 1 |
| Turgeon, R | 1 |
| Lawton, MT | 1 |
| Vates, GE | 1 |
| Sánchez Arguiano, J | 1 |
| Hernández-Hernández, MA | 1 |
| Jáuregui Solórzano, RA | 1 |
| Maldonado-Vega, S | 1 |
| González Mandly, A | 1 |
| Burón Mediavilla, J | 1 |
| Diringer, MN | 2 |
| Zazulia, AR | 1 |
| Adami, D | 1 |
| Berkefeld, J | 1 |
| Platz, J | 1 |
| Konczalla, J | 1 |
| Pfeilschifter, W | 1 |
| Weidauer, S | 1 |
| Wagner, M | 1 |
| Yi-Chou Wang, A | 1 |
| Samseethong, T | 1 |
| Suansanae, T | 1 |
| Veerasarn, K | 1 |
| Liengudom, A | 1 |
| Suthisisang, C | 1 |
| Mitra, R | 1 |
| Dube, SK | 1 |
| Jain, V | 1 |
| Macdonald, RL | 1 |
| Jaja, B | 1 |
| Cusimano, MD | 1 |
| Etminan, N | 1 |
| Hanggi, D | 1 |
| Hasan, D | 1 |
| Ilodigwe, D | 1 |
| Lantigua, H | 1 |
| Le Roux, P | 1 |
| Lo, B | 1 |
| Louffat-Olivares, A | 1 |
| Mayer, S | 1 |
| Molyneux, A | 1 |
| Quinn, A | 1 |
| Schweizer, TA | 1 |
| Schenk, T | 1 |
| Spears, J | 1 |
| Todd, M | 1 |
| Torner, J | 1 |
| Vergouwen, MD | 1 |
| Wong, GK | 2 |
| Singh, J | 1 |
| Rank, W | 1 |
| Raya, AK | 1 |
| Koskimäki, J | 1 |
| Tarkia, M | 1 |
| Ahtola-Sätilä, T | 1 |
| Saloranta, L | 1 |
| Simola, O | 1 |
| Forsback, AP | 1 |
| Laakso, A | 1 |
| Frantzén, J | 1 |
| Sandow, N | 1 |
| Diesing, D | 1 |
| Sarrafzadeh, A | 1 |
| Vajkoczy, P | 1 |
| Wolf, S | 1 |
| Goel, R | 1 |
| Aggarwal, A | 1 |
| Salunke, P | 1 |
| Kumar, A | 1 |
| Chhabra, R | 1 |
| Cho, S | 1 |
| Bales, J | 1 |
| Tran, TK | 1 |
| Korab, G | 1 |
| Khandelwal, N | 1 |
| Joffe, AM | 1 |
| Naidech, AM | 1 |
| Liebling, SM | 1 |
| Duran, IM | 1 |
| Ault, ML | 1 |
| Tang, W | 1 |
| Feng, H | 1 |
| Chen, Z | 1 |
| Miu, H | 1 |
| Pan, J | 1 |
| Lin, J | 1 |
| Zhu, G | 1 |
| Sun, LQ | 1 |
| Slivka, AP | 1 |
| Koenig, MA | 1 |
| Aburto-Murrieta, Y | 1 |
| Marquez-Romero, JM | 1 |
| Bonifacio-Delgadillo, D | 1 |
| López, I | 1 |
| Hernández-Curiel, B | 1 |
| Ko, CN | 1 |
| Lee, IW | 1 |
| Cho, SY | 1 |
| Lee, SH | 1 |
| Park, SU | 1 |
| Koh, JS | 1 |
| Park, JM | 1 |
| Kim, GK | 1 |
| Bae, HS | 1 |
| Chalouhi, N | 1 |
| Jabbour, P | 1 |
| Ibrahim, I | 1 |
| Starke, RM | 1 |
| Younes, P | 1 |
| El Hage, G | 1 |
| Samaha, E | 1 |
| LeStrange, DG | 1 |
| Stiefel, MF | 1 |
| Heuer, GG | 1 |
| Abrahams, JM | 1 |
| Bloom, S | 1 |
| Smith, MJ | 1 |
| Maloney-Wilensky, E | 1 |
| Grady, MS | 1 |
| LeRoux, PD | 1 |
| Han, RQ | 1 |
| Wang, BG | 1 |
| Li, SR | 1 |
| Wang, EZ | 1 |
| Liu, W | 1 |
| Wang, S | 1 |
| Zhao, JZ | 1 |
| Wanke, I | 1 |
| Gizewski, E | 1 |
| Dörfler, A | 1 |
| Stolke, D | 1 |
| Forsting, M | 1 |
| Poon, WS | 1 |
| Schmid-Elsaesser, R | 1 |
| Kunz, M | 1 |
| Zausinger, S | 1 |
| Prueckner, S | 1 |
| Briegel, J | 1 |
| Steiger, HJ | 3 |
| van den Bergh, WM | 2 |
| Mees, SM | 1 |
| Rinkel, GJ | 4 |
| Dorhout Mees, SM | 1 |
| Feigin, VL | 2 |
| Algra, A | 2 |
| Vermeulen, M | 2 |
| van Gijn, J | 3 |
| Tavernier, B | 1 |
| Decamps, F | 1 |
| Vega, E | 1 |
| Poidevin, P | 1 |
| Verdin, M | 1 |
| Riegel, B | 4 |
| Abdennour, L | 1 |
| Lejean, L | 1 |
| Bonneville, F | 1 |
| Boch, AL | 1 |
| Puybasset, L | 1 |
| Oran, I | 1 |
| Cinar, C | 1 |
| Kamath, S | 1 |
| Gadhinglajkar, SV | 1 |
| Allen, GS | 1 |
| Ahn, HS | 1 |
| Preziosi, TJ | 1 |
| Battye, R | 1 |
| Boone, SC | 2 |
| Chou, SN | 1 |
| Kelly, DL | 1 |
| Weir, BK | 2 |
| Crabbe, RA | 1 |
| Lavik, PJ | 1 |
| Rosenbloom, SB | 1 |
| Dorsey, FC | 1 |
| Ingram, CR | 1 |
| Mellits, DE | 1 |
| Bertsch, LA | 1 |
| Boisvert, DP | 1 |
| Hundley, MB | 1 |
| Johnson, RK | 1 |
| Strom, JA | 1 |
| Transou, CR | 1 |
| Auer, LM | 10 |
| Ljunggren, B | 11 |
| Brandt, L | 15 |
| Säveland, H | 8 |
| Nilsson, PE | 1 |
| Cronqvist, S | 1 |
| Andersson, KE | 5 |
| Vinge, E | 4 |
| Suzuki, A | 2 |
| Yasui, N | 1 |
| Ito, Z | 2 |
| Ohta, H | 1 |
| Zhang, P | 1 |
| Wang, B | 1 |
| Wang, E | 1 |
| Chen, X | 1 |
| Ohman, J | 6 |
| Proust, F | 2 |
| Hannequin, D | 1 |
| Langlois, O | 2 |
| Freger, P | 4 |
| Creissard, P | 4 |
| Golfinos, JG | 1 |
| Thompson, BG | 1 |
| Zabramski, JM | 1 |
| Spetzler, RF | 1 |
| Pickard, JD | 1 |
| Walker, V | 1 |
| Zygmunt, S | 1 |
| Smythe, J | 1 |
| Fritschi, J | 1 |
| Seiler, RW | 4 |
| Boecher-Schwarz, HG | 1 |
| Ungersboeck, K | 1 |
| Ulrich, P | 1 |
| Fries, G | 1 |
| Wild, A | 1 |
| Perneczky, A | 2 |
| Weir, B | 1 |
| MacDonald, L | 1 |
| Mercier, P | 1 |
| Alhayek, G | 1 |
| Rizk, T | 1 |
| Fournier, D | 1 |
| Menei, P | 1 |
| Guy, G | 1 |
| Hütter, BO | 1 |
| Gilsbach, JM | 6 |
| Dorsch, NW | 3 |
| Compton, JS | 1 |
| Tapaninaho, A | 1 |
| Hernesniemi, J | 1 |
| Vapalahti, M | 1 |
| Niskanen, M | 1 |
| Kari, A | 1 |
| Luukkonen, M | 1 |
| Puranen, M | 1 |
| Seifert, V | 1 |
| Rousseaux, P | 1 |
| Gomis, P | 1 |
| Bazin, A | 1 |
| Peruzzi, P | 1 |
| Scherpereel, B | 1 |
| Bernard, MH | 1 |
| Bertault, R | 1 |
| Graftieaux, JP | 1 |
| Laumer, R | 1 |
| Steinmeier, R | 1 |
| Gönner, F | 1 |
| Vogtmann, T | 1 |
| Priem, R | 1 |
| Fahlbusch, R | 1 |
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| Karadimov, D | 1 |
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| Romner, B | 5 |
| Porchet, F | 1 |
| Chioléro, R | 1 |
| de Tribolet, N | 1 |
| Hauerberg, J | 1 |
| Rosenørn, J | 1 |
| Skriver, EB | 1 |
| Haley, EC | 1 |
| Kassell, NF | 1 |
| Apperson-Hansen, C | 1 |
| Maile, MH | 1 |
| Alves, WM | 1 |
| Radhakrishnan, D | 1 |
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| Duan, A | 1 |
| Ding, Y | 1 |
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| Findlay, JM | 1 |
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| Ohinmaa, A | 1 |
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| Hepaguşlar, H | 1 |
| Balcioglu, T | 1 |
| Uyar, M | 1 |
| Origitano, TC | 1 |
| Reichman, OH | 1 |
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| Hillman, J | 4 |
| Edner, G | 1 |
| Jakobsson, KE | 1 |
| Algers, G | 1 |
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| Westergren, H | 1 |
| Mourier, KL | 1 |
| George, B | 1 |
| Raggueneau, JL | 1 |
| Tran Dinh, YR | 1 |
| Lot, G | 1 |
| Boissonnet, H | 1 |
| Cophignon, J | 1 |
| Ryman, T | 2 |
| Levesque, H | 1 |
| Sevrain, L | 2 |
| Courtois, H | 1 |
| Fodstad, H | 1 |
| Servo, A | 2 |
| Heiskanen, O | 4 |
| Juvela, S | 1 |
| Kaste, M | 1 |
| Lee, KC | 1 |
| Nirkko, AC | 1 |
| Bracard, S | 1 |
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| Marchal, JC | 2 |
| Ducrocq, X | 2 |
| Per, A | 1 |
| Czorny, A | 1 |
| Islak, C | 1 |
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| Roland, J | 1 |
| Lepoire, J | 2 |
| Tettenborn, D | 1 |
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| Reulen, HJ | 3 |
| von Holst, H | 1 |
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| von Essen, C | 3 |
| Conzen, MA | 1 |
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| Shiino, A | 1 |
| Kidooka, M | 1 |
| Adams, HP | 2 |
| Mathiesen, T | 1 |
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| Wroński, J | 1 |
| Abraszko, R | 1 |
| Berny, W | 1 |
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| Messeter, K | 3 |
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| Ryding, E | 2 |
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| Grob, R | 1 |
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| Auer, T | 1 |
| Ljunggren, BC | 1 |
| Brandt, JL | 1 |
| Säveland, HG | 1 |
| Nilsson, LG | 1 |
| Rosendal-Helgesen, S | 1 |
| Gilsbach, J | 1 |
| Groeger, U | 1 |
| Harders, A | 2 |
| Oppel, F | 1 |
| Saeveland, H | 1 |
| Nowak, G | 1 |
| Arnold, H | 1 |
| Winkler, D | 1 |
| Freckmann, N | 1 |
| Adams, CB | 1 |
| Stullken, EH | 2 |
| Johnston, WE | 1 |
| Prough, DS | 2 |
| Balestrieri, FJ | 2 |
| McWhorter, JM | 2 |
| Kazner, E | 1 |
| Sprung, C | 1 |
| Adelt, D | 1 |
| Ammerer, HP | 1 |
| Karnick, R | 1 |
| Baumann, H | 1 |
| Böker, DK | 2 |
| Grotenhuis, JA | 1 |
| Jaksche, H | 2 |
| Istaitih, AR | 1 |
| Koos, WT | 1 |
| Gaab, M | 1 |
| Meinig, G | 1 |
| Muizelaar, JP | 1 |
| Ausman, JI | 1 |
| Diaz, FG | 1 |
| Malik, GM | 1 |
| Fielding, AS | 1 |
| Son, CS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Evaluation of Effectiveness and Safety of the CorPath® GRX System in Endovascular Embolization Procedures of Cerebral Aneurysms[NCT04236856] | 120 participants (Actual) | Interventional | 2020-08-21 | Completed | |||
| Prevention of Cerebral Vasospasm Following Aneurysmal Subarachnoid Hemorrhage Through Treatment With Intravenous Autologous Cerebrospinal Fluid - a Pilot Trial.[NCT04490161] | 20 participants (Anticipated) | Interventional | 2020-01-01 | Recruiting | |||
| Efficacy and Safety of Cilostazol-Nimodipine Combined Therapy on Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage (aSAH): A Prospective, Randomized, Double-Blinded, Placebo-Controlled Trial[NCT04148105] | Phase 4 | 120 participants (Anticipated) | Interventional | 2019-11-01 | Recruiting | ||
| Neuroprotective Effect of Dapsone in Patients With Aneurysmal Subarachnoid Hemorrhage: Prospective, Randomized, Double-Blinded, Placebo-Controlled, Clinical Trial[NCT05131295] | Phase 3 | 49 participants (Actual) | Interventional | 2007-09-05 | Completed | ||
| The Intra-arterial Vasospasm Trial(iVAST)- A Multi-center Randomized Study[NCT01996436] | Phase 4 | 330 participants (Anticipated) | Interventional | 2016-08-29 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
26 reviews available for nimodipine and Aneurysm, Anterior Cerebral Artery
| Article | Year |
|---|---|
Effectiveness comparisons of drug therapies for postoperative aneurysmal subarachnoid hemorrhage patients: network meta‑analysis and systematic review.
Topics: Cardiovascular Agents; Cilostazol; Humans; Intracranial Aneurysm; Network Meta-Analysis; Neuroprotec | 2021 |
Subarachnoid Hemorrhage.
Topics: Adolescent; Aneurysm, Ruptured; Angiography; Brain; Calcium Channel Blockers; Endovascular Procedure | 2017 |
Aneurysmal Subarachnoid Hemorrhage: Strategies for Preventing Vasospasm in the Intensive Care Unit.
Topics: Calcium Channel Blockers; Delayed-Action Preparations; Humans; Intensive Care Units; Intracranial An | 2017 |
Coadjuvant Treatment of Vasospasm in Ruptured Unsecured Cerebral Aneurysms with Aggressive Angioplasty, Intra-Arterial Nimodipine, and Aneurysm Embolization.
Topics: Adult; Aged; Aneurysm, Ruptured; Angioplasty; Combined Modality Therapy; Embolization, Therapeutic; | 2018 |
SAHIT Investigators--on the outcome of some subarachnoid hemorrhage clinical trials.
Topics: Antioxidants; Brain Infarction; Calcium Channel Blockers; Critical Care; Dioxanes; Drug Therapy, Com | 2013 |
Treatment of subarachnoid hemorrhage.
Topics: Brain Ischemia; Female; Humans; Intracranial Aneurysm; Male; Nimodipine; Practice Guidelines as Topi | 2014 |
Management of delayed cerebral ischemia after subarachnoid hemorrhage.
Topics: Angioplasty, Balloon; Brain Ischemia; Calcium Channel Blockers; Cardiovascular Agents; Cerebral Angi | 2012 |
Calcium antagonists for aneurysmal subarachnoid haemorrhage.
Topics: Calcium Channel Blockers; Humans; Intracranial Aneurysm; Nimodipine; Randomized Controlled Trials as | 2007 |
[Treatment of subarachnoid hemorrhage].
Topics: Calcium Channel Blockers; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Nimodipine; Sub | 1994 |
Cerebral vasospasm.
Topics: Aneurysm, Ruptured; Blood Pressure; Blood Volume; Brain Ischemia; Catheterization; Cerebral Infarcti | 1993 |
[Neurosurgical therapy of subarachnoid hemorrhage. Microsurgical techniques--early postoperative nimodipine administration].
Topics: Aged; Aneurysm, Ruptured; Combined Modality Therapy; Drug Administration Schedule; Humans; Intracran | 1993 |
Calcium antagonists in patients with aneurysmal subarachnoid hemorrhage: a systematic review.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium Channel Blockers; Humans; Intracranial Aneury | 1998 |
The association of tranexamic acid and nimodipine in the pre-operative treatment of ruptured intracranial aneurysms.
Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Antifibrinolytic Agents; Antihypertensive Agents | 1998 |
Poor-grade subarachnoid hemorrhage patients: the use of nimodipine and other optional treatments.
Topics: Aneurysm, Ruptured; Clinical Trials as Topic; Humans; Intracranial Aneurysm; Nimodipine; Subarachnoi | 1999 |
Subarachnoid haemorrhage: diagnosis, causes and management.
Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Antihypertensive Agents; Brain Ischemia; Ce | 2001 |
[Vasospasm, early surgery and nimodipine. A series of 120 consecutive cases of surgically treated ruptured aneurysm].
Topics: Adolescent; Adult; Aged; Aneurysm, Ruptured; Female; Glasgow Coma Scale; Humans; Intracranial Aneury | 1992 |
[Value of the measurement of cerebral blood flow before and after diamox injection in predicting clinical vasospasm and final outcome in aneurysmal subarachnoid hemorrhage].
Topics: Acetazolamide; Cerebrovascular Circulation; Female; Humans; Intracranial Aneurysm; Male; Nimodipine; | 1991 |
Prevention and treatment of delayed ischemic dysfunction in patients with aneurysmal subarachnoid hemorrhage.
Topics: Brain Ischemia; Double-Blind Method; Humans; Intracranial Aneurysm; Meta-Analysis as Topic; Nimodipi | 1990 |
[Ca antagonists in neurosurgical practice].
Topics: Animals; Anticonvulsants; Brain; Calcium Channel Blockers; Cerebral Infarction; Disease Models, Anim | 1990 |
Calcium antagonists in the management of patients with aneurysmal subarachnoid hemorrhage: a review.
Topics: Calcium Channel Blockers; Cerebral Infarction; Humans; Intracranial Aneurysm; Ischemic Attack, Trans | 1990 |
[Intravascular volume expansion and intravenous nimodipine in the treatment of cerebral vasospasm after surgical treatment of intracranial aneurysm].
Topics: Adult; Cerebral Arterial Diseases; Dopamine; Fluid Therapy; Hemodynamics; Humans; Infusions, Intrave | 1990 |
[Epidemiology of meningeal hemorrhage caused by aneurysmal rupture (report of 600 cases)].
Topics: Adult; Age Factors; Female; Follow-Up Studies; Glasgow Coma Scale; Health Surveys; Humans; Intracran | 1990 |
Nimodipine in the prevention of ischaemic deficits after aneurysmal subarachnoid haemorrhage. An analysis of recent clinical studies.
Topics: Brain; Clinical Trials as Topic; Humans; Injections, Intravenous; Intracranial Aneurysm; Ischemic At | 1988 |
[Prevention of cerebral vasospasm caused by the rupture of intracranial aneurysms].
Topics: Cerebral Hemorrhage; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Nimodipine; Rupture, | 1988 |
Aneurysmal subarachnoid hemorrhage: prevention of delayed ischemic dysfunction with intravenous nimodipine.
Topics: Brain Ischemia; Clinical Trials as Topic; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; | 1987 |
[Vascular spasm and cerebral ischemia after meningeal hemorrhage caused by rupture of an aneurysm].
Topics: Brain Ischemia; Calcium Channel Blockers; Cerebral Angiography; Electroencephalography; Fibrin Fibri | 1986 |
37 trials available for nimodipine and Aneurysm, Anterior Cerebral Artery
| Article | Year |
|---|---|
The effect of nimodipine on cerebral oxygenation in patients with poor-grade subarachnoid hemorrhage.
Topics: Aged; Brain; Calcium Channel Blockers; Female; Humans; Intracranial Aneurysm; Intracranial Pressure; | 2004 |
[The effect of intraoperative continuous nimodipine infusion on cerebral vasospasm during intracranial aneurysm surgery].
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Intravenous; Female; Huma | 2004 |
Intravenous magnesium versus nimodipine in the treatment of patients with aneurysmal subarachnoid hemorrhage: a randomized study.
Topics: Adult; Aged; Brain Ischemia; Calcium Channel Blockers; Cerebral Angiography; Cerebral Infarction; Fe | 2006 |
Cerebral arterial spasm--a controlled trial of nimodipine in patients with subarachnoid hemorrhage.
Topics: Adolescent; Adult; Aged; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Fe | 1983 |
Preliminary study on controlled hypotension induced by nimodipine in craniocerebral surgery.
Topics: Adolescent; Adult; Antihypertensive Agents; Child; Female; Humans; Hypotension, Controlled; Intracra | 1995 |
Experience with nimodipine in aneurysmal subarachnoid haemorrhage.
Topics: Brain Ischemia; Double-Blind Method; Humans; Intracranial Aneurysm; Middle Aged; Nimodipine; Prospec | 1993 |
A randomized, double-blind, vehicle-controlled trial of tirilazad mesylate in patients with aneurysmal subarachnoid hemorrhage: a cooperative study in North America.
Topics: Administration, Oral; Anticonvulsants; Calcium Channel Blockers; Cerebral Angiography; Clinical Prot | 1997 |
Haemodynamic effects of intravenous nimodipine following aneurysmal subarachnoid haemorrhage: implications for monitoring.
Topics: Adult; Aged; Calcium Channel Blockers; Cardiac Catheterization; Hemodynamics; Humans; Hypotension; I | 1997 |
Causes of morbidity and mortality following intracranial aneurysm rupture.
Topics: Adult; Aged; Aneurysm, Ruptured; Angioplasty, Balloon; Cause of Death; Employment; Female; Glasgow C | 1998 |
Cost-effectiveness analysis of nimodipine treatment after aneurysmal subarachnoid hemorrhage and surgery.
Topics: Adolescent; Adult; Aged; Aneurysm, Ruptured; Combined Modality Therapy; Cost-Benefit Analysis; Doubl | 1999 |
The effects of nimodipine on vecuronium-induced neuromuscular blockade.
Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Calcium Channel Block | 2000 |
Raised plasma endothelin in aneurysmal subarachnoid haemorrhage.
Topics: Endothelins; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Nimodipine; Peptides; Prospe | 1990 |
Long-term effects of nimodipine on cerebral infarcts and outcome after aneurysmal subarachnoid hemorrhage and surgery.
Topics: Adolescent; Adult; Aged; Cause of Death; Cerebral Infarction; Double-Blind Method; Female; Humans; I | 1991 |
Prevention and treatment of delayed ischemic dysfunction in patients with aneurysmal subarachnoid hemorrhage.
Topics: Brain Ischemia; Double-Blind Method; Humans; Intracranial Aneurysm; Meta-Analysis as Topic; Nimodipi | 1990 |
Early aneurysm surgery and preventive therapy with intravenously administered nimodipine: a multicenter, double-blind, dose-comparison study.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injections, Intravenous; Intr | 1990 |
Calcium antagonists in the management of patients with aneurysmal subarachnoid hemorrhage: a review.
Topics: Calcium Channel Blockers; Cerebral Infarction; Humans; Intracranial Aneurysm; Ischemic Attack, Trans | 1990 |
Nimodipine for cerebral vasospasm after subarachnoid hemorrhage.
Topics: Administration, Oral; Clinical Trials as Topic; Humans; Infusions, Intravenous; Intracranial Aneurys | 1989 |
Reference: nimodipine in cerebral vasospasm.
Topics: Clinical Trials as Topic; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Nimodipine; Rup | 1989 |
[Intravenous nimodipine in the treatment of cerebral vasospasm following subarachnoid hemorrhage caused by aneurysm rupture: a comparative multicenter study].
Topics: Adult; Double-Blind Method; Female; Humans; Infusions, Intravenous; Intracranial Aneurysm; Ischemic | 1989 |
Timing of operation for ruptured supratentorial aneurysms: a prospective randomized study.
Topics: Adolescent; Adult; Aged; Brain Ischemia; Circle of Willis; Evaluation Studies as Topic; Humans; Intr | 1989 |
[Curative action of intravenous nimodipine on cerebral vasospasm after aneurysm rupture].
Topics: Clinical Trials as Topic; Humans; Injections, Intravenous; Intracranial Aneurysm; Ischemic Attack, T | 1987 |
Nimodipine therapy in poor-grade aneurysm patients.
Topics: Clinical Trials as Topic; Humans; Intracranial Aneurysm; Nimodipine | 1988 |
Effect of nimodipine on the outcome of patients after aneurysmal subarachnoid hemorrhage and surgery.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Humans; Intracranial Aneurys | 1988 |
Nimodipine treatment in poor-grade aneurysm patients.
Topics: Clinical Trials as Topic; Humans; Intracranial Aneurysm; Nimodipine | 1988 |
Therapeutic trial of intravenous nimodipine in patients with established cerebral vasospasm after rupture of intracranial aneurysms.
Topics: Adult; Clinical Trials as Topic; Female; Hemodynamics; Humans; Hypotension; Injections, Intravenous; | 1988 |
Nimodipine in the prevention of ischaemic deficits after aneurysmal subarachnoid haemorrhage. An analysis of recent clinical studies.
Topics: Brain; Clinical Trials as Topic; Humans; Injections, Intravenous; Intracranial Aneurysm; Ischemic At | 1988 |
[Treatment of vasospasm in aneurysmal meningeal hemorrhage using intravenous nimodipine. Multicenter cooperative study].
Topics: Double-Blind Method; Female; Humans; Injections, Intravenous; Intracranial Aneurysm; Ischemic Attack | 1988 |
[Therapy of aneurysm-induced subarachnoid hemorrhage].
Topics: Follow-Up Studies; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Nimodipine; Postoperat | 1988 |
Nimodipine treatment in poor-grade aneurysm patients. Results of a multicenter double-blind placebo-controlled trial.
Topics: Adolescent; Adult; Aged; Antifibrinolytic Agents; Brain Ischemia; Cerebral Angiography; Cerebral Inf | 1988 |
Controlled study of nimodipine in aneurysm patients treated early after subarachnoid hemorrhage.
Topics: Adolescent; Adult; Aged; Cardiovascular System; Cerebrovascular Circulation; Clinical Trials as Topi | 1988 |
Aneurysmal subarachnoid hemorrhage: prevention of delayed ischemic dysfunction with intravenous nimodipine.
Topics: Brain Ischemia; Clinical Trials as Topic; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; | 1987 |
Early intervention with nimodipine in subarachnoid haemorrhage.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cerebral Angiography; Cerebrovascular Circulation; Double-B | 1987 |
Cerebral vasospasm and calcium channel blockade. Nimodipine treatment in patients with aneurysmal subarachnoid hemorrhage.
Topics: Brain Ischemia; Carotid Artery Diseases; Carotid Artery, Internal; Clinical Trials as Topic; Humans; | 1986 |
Prevention of vasospasm in subarachnoid haemorrhage. A controlled study with nimodipine.
Topics: Adolescent; Adult; Aged; Cerebral Angiography; Clinical Trials as Topic; Double-Blind Method; Humans | 1986 |
The relationship between timing of surgery and operative complications in aneurysmal subarachnoid hemorrhage.
Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Intracranial Aneurysm; Middle Aged; Nimodipin | 1987 |
Implications of nimodipine prophylaxis of cerebral vasospasm on anesthetic management during intracranial aneurysm clipping.
Topics: Anesthesia; Calcium Channel Blockers; Cerebral Hemorrhage; Cerebrovascular Circulation; Clinical Tri | 1985 |
Preventive nimodipine and acute aneurysm surgery. Heading for the control of complications after aneurysmal subarachnoid hemorrhage.
Topics: Animals; Arteries; Brain Ischemia; Calcium Channel Blockers; Cats; Cerebral Revascularization; Clini | 1985 |
101 other studies available for nimodipine and Aneurysm, Anterior Cerebral Artery
| Article | Year |
|---|---|
Current management of subarachnoid hemorrhage in a northern urban Chinese population: a multi-center surveillance study.
Topics: Aged; Aneurysm, Ruptured; Case-Control Studies; Female; Humans; Intracranial Aneurysm; Middle Aged; | 2023 |
May levosimendan be safe and effective in refractory vasospasm despite adequate treatment with repeated angiography and milrinone infusion after subarachnoid haemorrhage?
Topics: Aneurysm, Ruptured; Cardiotonic Agents; Cerebral Angiography; Cerebrospinal Fluid Leak; Computed Tom | 2019 |
Impact of Stereotactic Ventriculocisternostomy on Delayed Cerebral Infarction and Outcome After Subarachnoid Hemorrhage.
Topics: Aged; Aneurysm, Ruptured; Cerebral Infarction; Female; Fibrinolytic Agents; Humans; Intracranial Ane | 2020 |
Early strategy of scepter XC balloon angioplasty and simultaneous Nimodipine infusion for vasospasm following ruptured aneurysm.
Topics: Adult; Aged; Aneurysm, Ruptured; Angioplasty, Balloon; Computed Tomography Angiography; Female; Huma | 2020 |
Comment: The Effects of 14 Versus 21 Days of Nimodipine Therapy on Neurological Outcomes in Aneurysmal Subarachnoid Hemorrhage Patients.
Topics: Calcium Channel Blockers; Humans; Intracranial Aneurysm; Nimodipine; Subarachnoid Hemorrhage | 2017 |
Stellate ganglion block as rescue therapy in refractory vasospasm after subarachnoid hemorrhage.
Topics: Anesthetics, Local; Aneurysm, Ruptured; Arm; Bupivacaine; Humans; Intracranial Aneurysm; Middle Aged | 2019 |
Complication rate of intraarterial treatment of severe cerebral vasospasm after subarachnoid hemorrhage with nimodipine and percutaneous transluminal balloon angioplasty: Worth the risk?
Topics: Adult; Aged; Angioplasty; Aortic Dissection; Cerebral Infarction; Combined Modality Therapy; Female; | 2019 |
Impact of Early Versus Late Intravenous Followed by Oral Nimodipine Treatment on the Occurrence of Delayed Cerebral Ischemia Among Patients With Aneurysm Subarachnoid Hemorrhage.
Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Brain Ischemia; Drug Administration | 2018 |
Isolated diastolic hypotension: A unique complication of intra-arterial nimodipine infusion!!
Topics: Aged; Angiography, Digital Subtraction; Anterior Cerebral Artery; Blood Pressure; Diastole; Electroc | 2020 |
In brief: nimodipine oral solution (Nymalize).
Topics: Administration, Oral; Aneurysm, Ruptured; Calcium Channel Blockers; Drug Approval; Humans; Intracran | 2013 |
Using nimodipine for patients with aneurysmal subarachnoid hemorrhage.
Topics: Calcium Channel Blockers; Humans; Intracranial Aneurysm; Nimodipine; Practice Guidelines as Topic; R | 2014 |
Intracranial biodegradable silica-based nimodipine drug release implant for treating vasospasm in subarachnoid hemorrhage in an experimental healthy pig and dog model.
Topics: Animals; Delayed-Action Preparations; Disease Models, Animal; Dogs; Intracranial Aneurysm; Nimodipin | 2015 |
Nimodipine Dose Reductions in the Treatment of Patients with Aneurysmal Subarachnoid Hemorrhage.
Topics: Adult; Calcium Channel Blockers; Cerebral Infarction; Female; Humans; Intracranial Aneurysm; Male; M | 2016 |
Is intra arterial nimodipine really beneficial in vasospasm following aneurysmal subarachnoid haemorrhage?
Topics: Adult; Aged; Female; Humans; Infusions, Intra-Arterial; Intracranial Aneurysm; Male; Middle Aged; Ni | 2016 |
Effects of 14 Versus 21 Days of Nimodipine Therapy on Neurological Outcomes in Aneurysmal Subarachnoid Hemorrhage Patients.
Topics: Adult; Aged; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Utilization; Female; H | 2016 |
Packed red blood cell age does not impact adverse events or outcomes after subarachnoid haemorrhage.
Topics: Adult; Aged; Blood Preservation; Cerebral Infarction; Coma; Erythrocyte Aging; Erythrocyte Transfusi | 2011 |
Microsurgical treatment of ruptured intracranial aneurysm: a 120-case analysis.
Topics: Adult; Aged; Aneurysm, Ruptured; Female; Follow-Up Studies; Humans; Intracranial Aneurysm; Male; Mic | 2011 |
Sensitivity of computed tomography angiography vs catheter angiography in the detection of a ruptured intracranial infectious aneurysm in a pregnant woman.
Topics: Adult; Aneurysm, Infected; Aneurysm, Ruptured; Anti-Bacterial Agents; Anticonvulsants; Brain; Cathet | 2012 |
Endovascular treatment: balloon angioplasty versus nimodipine intra-arterial for medically refractory cerebral vasospasm following aneurysmal subarachnoid hemorrhage.
Topics: Adult; Angiography, Digital Subtraction; Angioplasty, Balloon; Chi-Square Distribution; Female; Huma | 2012 |
Acupuncture for cerebral vasospasm after subarachnoid hemorrhage: a retrospective case-control study.
Topics: Acupuncture Therapy; Adult; Aged; Aneurysm, Ruptured; Case-Control Studies; Cerebral Angiography; Co | 2013 |
Surgical treatment of ruptured anterior circulation aneurysms: comparison of pterional and supraorbital keyhole approaches.
Topics: Anesthesia, General; Aneurysm, Ruptured; Calcium Channel Blockers; Female; Glasgow Outcome Scale; Hu | 2013 |
The pharmacologic treatment of vasospasm after subarachnoid hemorrhage: a case study.
Topics: Adult; Blood Pressure; Brain; Cardiotonic Agents; Dobutamine; Female; Fluid Therapy; Hemodilution; H | 2003 |
[Stenting plus coiling: dangerous or helpful?].
Topics: Acute Disease; Aneurysm, Ruptured; Angiography, Digital Subtraction; Aspirin; Calcium Channel Blocke | 2005 |
Use of phenytoin and other anticonvulsant prophylaxis in patients with aneurysmal subarachnoid hemorrhage.
Topics: Cognition Disorders; Drug Interactions; Humans; Intracranial Aneurysm; Nimodipine; Phenytoin; Seizur | 2005 |
Intravenous magnesium versus nimodipine in the treatment of patients with aneurysmal subarachnoid hemorrhage: a randomized study.
Topics: Adult; Aged; Brain Ischemia; Calcium Channel Blockers; Cerebral Angiography; Cerebral Infarction; Fe | 2006 |
[Systemic treatments of the vasospasm].
Topics: Hemodilution; Hemodynamics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hy | 2007 |
[Endovascular treatment of vasospasm following subarachnoid aneurysmal haemorrhage].
Topics: Calcium Channel Blockers; Humans; Intracranial Aneurysm; Nicardipine; Nimodipine; Nitroprusside; Pap | 2007 |
Continuous intra-arterial infusion of nimodipine during embolization of cerebral aneurysms associated with vasospasm.
Topics: Adult; Aged; Chemotherapy, Adjuvant; Embolization, Therapeutic; Female; Humans; Infusions, Intra-Art | 2008 |
Can changes in BIS provide clue to lower limit of cerebral autoregulation?
Topics: Adrenergic alpha-Agonists; Anesthesia, General; Antihypertensive Agents; Blood Pressure; Cerebrovasc | 2008 |
Acute operation and preventive nimodipine improve outcome in patients with ruptured cerebral aneurysms.
Topics: Adult; Female; Follow-Up Studies; Humans; Intracranial Aneurysm; Intraoperative Complications; Ische | 1984 |
Outcome in 60 consecutive patients treated with early aneurysm operation and intravenous nimodipine.
Topics: Adult; Combined Modality Therapy; Evaluation Studies as Topic; Female; Humans; Intracranial Aneurysm | 1984 |
Acute surgery of cerebral aneurysms and prevention of symptomatic vasospasm.
Topics: Adolescent; Adult; Aged; Cerebral Angiography; Follow-Up Studies; Humans; Intracranial Aneurysm; Isc | 1983 |
Intraoperative topical nimodipine after aneurysm clipping.
Topics: Administration, Topical; Calcium Channel Blockers; Humans; Intracranial Aneurysm; Intraoperative Per | 1984 |
Prevention of symptomatic vasospasm by topically applied nimodipine.
Topics: Administration, Topical; Adult; Aged; Calcium Channel Blockers; Female; Humans; Intracranial Aneurys | 1982 |
Causes of morbidity and mortality after ruptured aneurysm surgery in a series of 230 patients. The importance of control angiography.
Topics: Adolescent; Adult; Aged; Aneurysm, Ruptured; Brain Ischemia; Cerebral Angiography; Cerebral Hemorrha | 1995 |
Are the calcium antagonists really useful in cerebral aneurysmal surgery? A retrospective study.
Topics: Brain Ischemia; Calcium Channel Blockers; Humans; Intracranial Aneurysm; Neuropsychological Tests; N | 1994 |
Which are the major determinants for outcome in aneurysmal subarachnoid hemorrhage? A prospective total management study from a strictly unselected series.
Topics: Adult; Aged; Aneurysm, Ruptured; Brain Ischemia; Cause of Death; Disability Evaluation; Female; Foll | 1994 |
Effect of intraventricular haemorrhage and rebleeding following subarachnoid haemorrhage on CSF eicosanoids.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Brain Damage, Chronic; Cerebral Ventricles; Dexamethasone; Di | 1994 |
Current pattern of in-hospital aneurysmal rebleeds. Analysis of a series treated with individually timed surgery and intravenous nimodipine.
Topics: Adult; Aged; Aneurysm, Ruptured; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Neurologi | 1994 |
Transcranial Doppler diagnosis of cerebral vasospasm following subarachnoid haemorrhage: correlation and analysis of results in relation to the age of patients.
Topics: Adult; Age Factors; Aged; Aneurysm, Ruptured; Blood Flow Velocity; Cerebrovascular Circulation; Dose | 1994 |
Are the calcium antagonists really useful in cerebral aneurysmal surgery? A retrospective study.
Topics: Activities of Daily Living; Adult; Aged; Brain Ischemia; Calcium Channel Blockers; Cerebral Angiogra | 1994 |
Which neuropsychological deficits are hidden behind a good outcome (Glasgow = I) after aneurysmal subarachnoid hemorrhage?
Topics: Adult; Age Factors; Aphasia; Cognition Disorders; Female; Follow-Up Studies; Glasgow Coma Scale; Hum | 1993 |
Treatment of symptomatic vasospasm with nimodipine.
Topics: Adolescent; Adult; Aged; Cause of Death; Female; Glasgow Coma Scale; Humans; Infusions, Intravenous; | 1993 |
Shunt-dependent hydrocephalus after subarachnoid haemorrhage and aneurysm surgery: timing of surgery is not a risk factor.
Topics: Adult; Aneurysm, Ruptured; Cerebrospinal Fluid Shunts; Combined Modality Therapy; Female; Humans; Hy | 1993 |
[Comparison of 2 consecutive series of aneurysmal subarachnoid hemorrhage with or without nimodipine and study of the temperature curve].
Topics: Adult; Female; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Male; Middle Aged; Nimodip | 1993 |
Cerebral hemodynamics in subarachnoid hemorrhage evaluated by transcranial Doppler sonography. Part 1. Reliability of flow velocities in clinical management.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Flow Velocity; Brain Ischemia; Cerebral Arteries; | 1993 |
A strategy for analyzing multiple parameters with application to aneurysmal SAH patients all of them clipped but treated with and without cyclosporine.
Topics: Adult; Aged; Aneurysm, Ruptured; Cyclosporine; Drug Therapy, Combination; Female; Glasgow Coma Scale | 1993 |
[Controlled hypotension against a background of nimodipine during an operation on neurosurgical patients with hypertension].
Topics: Adolescent; Adult; Anesthesia, General; Antihypertensive Agents; Hemodynamics; Humans; Hypertension; | 1995 |
Is transcranial Doppler sonography useful in detecting late cerebral ischaemia after aneurysmal subarachnoid haemorrhage?
Topics: Adult; Aged; Calcium Channel Blockers; Cerebral Arteries; Humans; Intracranial Aneurysm; Ischemic At | 1996 |
Hypotensive effect of nimodipine during treatment for aneurysmal subarachnoid haemorrhage.
Topics: Administration, Oral; Adult; Aged; Aneurysm, Ruptured; Blood Pressure; Brain; Calcium Channel Blocke | 1995 |
Does nimodipine influence sex difference in outcome after aneurysmal subarachnoid haemorrhage?
Topics: Administration, Oral; Adolescent; Adult; Aged; Aneurysm, Ruptured; Brain Damage, Chronic; Brain Isch | 1996 |
[Comprehensive treatment of intracranial aneurysm complicated by postoperative vasospasm].
Topics: Adult; Aged; Calcium Channel Blockers; Combined Modality Therapy; Female; Hemodilution; Humans; Intr | 1996 |
The efficacy of an abbreviated course of nimodipine in patients with good-grade aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Intracranial Aneurysm; Length of Stay; Male; Middle | 1999 |
Prophylactic hypervolemia without calcium channel blockers in early aneurysm surgery.
Topics: Blood Volume; Brain; Hemodilution; Humans; Intracranial Aneurysm; Nimodipine; Postoperative Complica | 1992 |
Overall outcome in aneurysmal subarachnoid hemorrhage. A prospective study from neurosurgical units in Sweden during a 1-year period.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Female; Hemodilution; Humans; Hydrocephalus; Intr | 1992 |
Nimodipine evoked dilation of cerebral arteries early during the development of late vasospasm in subarachnoid hemorrhage.
Topics: Aged; Cerebral Angiography; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Male; Neurolo | 1991 |
Does nimodipine eliminate arterial hypertension as a prognostic risk factor in subarachnoid haemorrhage?
Topics: Adolescent; Adult; Aged; Female; Humans; Hypertension; Intracranial Aneurysm; Ischemic Attack, Trans | 1991 |
Advances in the management of victims struck by ruptured intracranial aneurysms.
Topics: Aged; History, 19th Century; History, 20th Century; History, Ancient; Humans; Intracranial Aneurysm; | 1990 |
Unfavorable outcome following early surgical repair of ruptured cerebral aneurysms--a critical review of 238 patients.
Topics: Aged; Cerebral Hemorrhage; Female; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Male; | 1991 |
Subarachnoid haemorrhage.
Topics: Brain Ischemia; Humans; Intracranial Aneurysm; Nimodipine; Referral and Consultation; Rupture, Spont | 1991 |
Angiographic vasospasm and release of platelet thromboxane after subarachnoid hemorrhage.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Cerebral Angiography; Female; Humans; Intracranial An | 1991 |
Surgery of intracranial aneurysms at Yonsei University: 780 cases.
Topics: Brain Ischemia; Cerebral Hemorrhage; Humans; Hydrocephalus; Intracranial Aneurysm; Nimodipine; Posto | 1991 |
Effect of nimodipine on cerebrovascular response to CO2 in asymptomatic individuals and patients with subarachnoid hemorrhage: a transcranial Doppler ultrasound study.
Topics: Adolescent; Adult; Aged; Blood Flow Velocity; Carbon Dioxide; Cerebral Arteries; Cerebrovascular Cir | 1990 |
Role of angioplasty in the treatment of symptomatic vascular spasm occurring in the post-operative course of intracranial ruptured aneurysms.
Topics: Adult; Angiography; Angioplasty, Balloon; Circle of Willis; Female; Humans; Intracranial Aneurysm; I | 1990 |
Delayed brainstem ischemia following rupture of a basilar artery aneurysm and its reversal by nimodipine.
Topics: Adult; Basilar Artery; Brain Ischemia; Brain Stem; Female; Humans; Intracranial Aneurysm; Nimodipine | 1990 |
Clinical experiences with nimodipine treatment in patients after SAH and aneurysm surgery.
Topics: Adolescent; Adult; Aged; Female; Humans; Infusions, Intravenous; Intracranial Aneurysm; Ischemic Att | 1990 |
[The value of a computer tomography scanner and controlled arteriography in the study of the results of aneurysm surgery. A series of 100 consecutive cases].
Topics: Adult; Aged; Aneurysm; Angiography; Carotid Artery Diseases; Cerebral Angiography; Cerebral Hemorrha | 1990 |
[Evaluation of the treatment of aneurysmal meningeal hemorrhage with antifibrinolytic agents, calcium inhibitors and maintenance of effective blood volume].
Topics: Adolescent; Adult; Aged; Cerebral Arterial Diseases; Child; Child, Preschool; Clinical Protocols; Fe | 1990 |
[Value of cerebral blood flow study with nimodipine test in intracranial aneurysm].
Topics: Adolescent; Adult; Aged; Brain Ischemia; Cerebral Arterial Diseases; Cerebrovascular Circulation; Fe | 1990 |
The relevance of the calcium channel blocker nimodipine in the therapy of cerebral aneurysms.
Topics: Adolescent; Adult; Aged; Cerebrovascular Circulation; Humans; Intracranial Aneurysm; Ischemic Attack | 1990 |
[Value of transcranial Doppler in the monitoring of aneurysmal subarachnoid hemorrhage treated with calcium inhibitors].
Topics: Brain; Follow-Up Studies; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Nimodipine; Sub | 1989 |
Anesthetic management of a patient with a giant intracranial aneurysm.
Topics: Adult; Aminocaproic Acid; Anesthesia, General; Electrocardiography; Humans; Intracranial Aneurysm; I | 1989 |
[Interaction of nimodipine and isoflurane in surgery of intracranial aneurysm].
Topics: Drug Interactions; Hemodynamics; Humans; Hypotension, Controlled; Intracranial Aneurysm; Intraoperat | 1989 |
[Does nimodipine improve the outcome of perioperative complications of aneurysm rupture? Results of systematic treatment].
Topics: Adolescent; Adult; Aged; Female; Follow-Up Studies; Humans; Intracranial Aneurysm; Ischemic Attack, | 1989 |
Morbidity and mortality after early aneurysm surgery--a prospective study with nimodipine prevention.
Topics: Adult; Aged; Brain Ischemia; Cerebral Arteries; Cerebral Hemorrhage; Cerebral Infarction; Combined M | 1989 |
Evaluation of the calcium-antagonist nimodipine for the prevention of vasospasm after aneurysmal subarachnoid haemorrhage. A prospective transcranial Doppler ultrasound study.
Topics: Adult; Aged; Blood Flow Velocity; Cerebrovascular Circulation; Female; Humans; Intracranial Aneurysm | 1987 |
Outcome of aneurysmal subarachnoid hemorrhage in a hospital population: a prospective study including early operation, intravenous nimodipine, and transcranial Doppler ultrasound.
Topics: Adolescent; Adult; Aged; Cerebrovascular Circulation; Female; Humans; Intracranial Aneurysm; Male; M | 1988 |
Intraoperative use of laser Doppler in the study of cerebral microvascular circulation.
Topics: Adult; Brain; Brain Neoplasms; Cerebrovascular Circulation; Female; Humans; Intracranial Aneurysm; M | 1988 |
Management of aneurysmal subarachnoid hemorrhage.
Topics: Aminocaproic Acid; Humans; Intracranial Aneurysm; Nervous System Diseases; Nicardipine; Nimodipine; | 1988 |
Results of treatment for cerebral saccular aneurysms in a small neurosurgical unit--evaluation of early operation and nimodipine treatment.
Topics: Humans; Intracranial Aneurysm; Nimodipine; Rupture, Spontaneous; Subarachnoid Hemorrhage | 1988 |
The calcium entry blocker nimodipine improves the quality of life of patients operated on for cerebral aneurysms. A 5-year follow-up analysis.
Topics: Activities of Daily Living; Adolescent; Adult; Aged; Female; Follow-Up Studies; Humans; Infusions, I | 1988 |
Early aneurysm surgery: a 7 year clinical practice report.
Topics: Cerebral Angiography; Cerebrospinal Fluid Shunts; Humans; Hydrocephalus; Intracranial Aneurysm; Isch | 1988 |
Thromboxane B2 levels in serum during continuous administration of nimodipine to patients with aneurysmal subarachnoid hemorrhage.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Intracranial Aneurysm; Nimodipine; Subarachnoid Hem | 1988 |
Significance of "ultra-early" rebleeding in subarachnoid hemorrhage.
Topics: Female; Hematoma; Humans; Intracranial Aneurysm; Male; Mental Disorders; Middle Aged; Nervous System | 1988 |
Nimodipine treatment of selected good-risk patients with subarachnoid hemorrhage: no significant difference between present and historical results.
Topics: Adolescent; Adult; Brain Ischemia; Child; Child, Preschool; Follow-Up Studies; Humans; Hypertension; | 1988 |
Prediction and prevention of delayed ischemic dysfunction in early aneurysm surgery.
Topics: Adult; Brain Ischemia; Cerebrovascular Circulation; Female; Humans; Hyperventilation; Intracranial A | 1987 |
Prediction and prevention of delayed ischemic dysfunction after aneurysmal subarachnoid hemorrhage and early operation.
Topics: Adult; Brain Ischemia; Cerebrovascular Circulation; Female; Humans; Intracranial Aneurysm; Male; Mid | 1987 |
[Effect of the calcium antagonist nimodipine on hemodynamics, gas exchange and endocrine parameters in opiate anesthesia].
Topics: Anesthesia, General; Cerebrovascular Circulation; Fentanyl; Hemodynamics; Hormones; Humans; Infusion | 1987 |
Computerized tomography and prognosis in early aneurysm surgery.
Topics: Cerebral Angiography; Follow-Up Studies; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; | 1986 |
Outcome in patients subjected to early aneurysm operation and intravenous nimodipine.
Topics: Adult; Aged; Follow-Up Studies; Humans; Infusions, Parenteral; Intracranial Aneurysm; Ischemic Attac | 1986 |
Prognosis in ruptured cerebral aneurysms with early operation and nimodipine prophylaxis.
Topics: Adult; Aged; Cisterna Magna; Female; Follow-Up Studies; Humans; Infusions, Parenteral; Injections; I | 1986 |
Pharmacokinetics of nimodipine in patients with aneurysmal subarachnoid haemorrhage.
Topics: Administration, Oral; Adult; Aged; Brain Ischemia; Calcium Channel Blockers; Female; Humans; Infusio | 1986 |
Nimodipine and early aneurysm operation in good condition SAH patients.
Topics: Administration, Topical; Adolescent; Adult; Aged; Female; Follow-Up Studies; Humans; Infusions, Pare | 1986 |
[Aneurysms of the auditory artery at the internal acoustic meatus].
Topics: Arteries; Cerebellum; Combined Modality Therapy; Ear, Inner; Humans; Intracranial Aneurysm; Male; Mi | 1986 |
Effect of early aneurysm surgery and nimodipine administration.
Topics: Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Nimodipine; Time Factors | 1987 |
Early aneurysm operation and vasospasm. Intracranial Doppler findings.
Topics: Adult; Calcium Channel Blockers; Circle of Willis; Female; Humans; Intracranial Aneurysm; Ischemic A | 1985 |
Delayed ischemic deterioration in patients with early aneurysm operation and intravenous nimodipine.
Topics: Brain Ischemia; Carotid Artery Diseases; Carotid Artery, Internal; Cerebral Arterial Diseases; Combi | 1986 |
The hemodynamic effects of nimodipine in patients anesthetized for cerebral aneurysm clipping.
Topics: Anesthesia, General; Blood Pressure; Calcium Channel Blockers; Hemodynamics; Humans; Intracranial An | 1985 |
Clinical experience with nimodipine in the prophylaxis of neurological deficits after subarachnoid hemorrhage.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Intracran | 1985 |
Nimodipine treatment of ischemic neurological deficits due to cerebral vasospasm after subarachnoid hemorrhage. Clinical results of a multicenter study.
Topics: Adult; Aged; Brain Ischemia; Drug Interactions; Female; Humans; Intracranial Aneurysm; Ischemic Atta | 1985 |
Current management of cerebral aneurysms: is it based on facts or myths?
Topics: Adult; Age Factors; Aged; Antifibrinolytic Agents; Cerebral Angiography; Humans; Hypotension, Contro | 1985 |