Page last updated: 2024-11-01

nimodipine and Allergic Encephalomyelitis

nimodipine has been researched along with Allergic Encephalomyelitis in 4 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Research Excerpts

ExcerptRelevanceReference
"Nimodipine treatment attenuated clinical EAE and spinal cord degeneration and promoted remyelination."5.46Nimodipine fosters remyelination in a mouse model of multiple sclerosis and induces microglia-specific apoptosis. ( Ergün, S; Hell, JW; Jörg, S; Koeniger, T; Kuerten, S; Linker, RA; Schampel, A; Scholz, CJ; Volovitch, O; Wischmeyer, E; Wunsch, M, 2017)
"Treatment with nimodipine restores spinal oxygenation and can rapidly improve function."1.56Nimodipine Reduces Dysfunction and Demyelination in Models of Multiple Sclerosis. ( Davies, AL; Del Rossi, N; Desai, RA; Dyson, A; Golay, X; Gustavson, B; Harvey, AR; Kaynezhad, P; Linington, C; Mackenzie, L; McElroy, D; Schiza, D; Singer, M; Smith, KJ; Tachrount, M; Tachtsidis, I; van der Putten, MA, 2020)
"Nimodipine treatment attenuated clinical EAE and spinal cord degeneration and promoted remyelination."1.46Nimodipine fosters remyelination in a mouse model of multiple sclerosis and induces microglia-specific apoptosis. ( Ergün, S; Hell, JW; Jörg, S; Koeniger, T; Kuerten, S; Linker, RA; Schampel, A; Scholz, CJ; Volovitch, O; Wischmeyer, E; Wunsch, M, 2017)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's3 (75.00)2.80

Authors

AuthorsStudies
Enders, M1
Weier, A1
Chunder, R1
An, Y1
Bremm, F1
Feigenspan, A1
Buettner, C1
Ekici, AB1
Mingardo, E1
Odermatt, B1
Kuerten, S2
Denaroso, GE1
Smith, Z1
Angeliu, CG1
Cheli, VT1
Wang, C1
Paez, PM1
Desai, RA1
Davies, AL1
Del Rossi, N1
Tachrount, M1
Dyson, A1
Gustavson, B1
Kaynezhad, P1
Mackenzie, L1
van der Putten, MA1
McElroy, D1
Schiza, D1
Linington, C1
Singer, M1
Harvey, AR1
Tachtsidis, I1
Golay, X1
Smith, KJ1
Schampel, A1
Volovitch, O1
Koeniger, T1
Scholz, CJ1
Jörg, S1
Linker, RA1
Wischmeyer, E1
Wunsch, M1
Hell, JW1
Ergün, S1

Other Studies

4 other studies available for nimodipine and Allergic Encephalomyelitis

ArticleYear
Impact of the Voltage-Gated Calcium Channel Antagonist Nimodipine on the Development of Oligodendrocyte Precursor Cells.
    International journal of molecular sciences, 2023, Feb-13, Volume: 24, Issue:4

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Differentiation; Encephalomyelitis

2023
Deletion of voltage-gated calcium channels in astrocytes decreases neuroinflammation and demyelination in a murine model of multiple sclerosis.
    Journal of neuroinflammation, 2023, Nov-14, Volume: 20, Issue:1

    Topics: Animals; Astrocytes; Calcium Channels; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experi

2023
Nimodipine Reduces Dysfunction and Demyelination in Models of Multiple Sclerosis.
    Annals of neurology, 2020, Volume: 88, Issue:1

    Topics: Animals; Calcium Channel Blockers; Disease Progression; Encephalomyelitis, Autoimmune, Experimental;

2020
Nimodipine fosters remyelination in a mouse model of multiple sclerosis and induces microglia-specific apoptosis.
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 04-18, Volume: 114, Issue:16

    Topics: Animals; Apoptosis; Calcium Channels, L-Type; Cells, Cultured; Disease Models, Animal; Encephalomyel

2017