nimodipine has been researched along with Age-Related Memory Disorders in 18 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nimodipine given 7-14 days after cerebral infarction for 3 months results in memory improvement." | 9.08 | Effect of nimodipine on memory after cerebral infarction. ( Cheng, S; Sim, TC; Sze, KH; Wong, E; Woo, J, 1998) |
| "Nimodipine given 7-14 days after cerebral infarction for 3 months results in memory improvement." | 5.08 | Effect of nimodipine on memory after cerebral infarction. ( Cheng, S; Sim, TC; Sze, KH; Wong, E; Woo, J, 1998) |
| "LPS-infused rats had significant memory deficits in the Morris water maze, and this deficit was ameliorated by treatment with nimodipine." | 1.42 | Calcium dysregulation via L-type voltage-dependent calcium channels and ryanodine receptors underlies memory deficits and synaptic dysfunction during chronic neuroinflammation. ( Adzovic, L; Crockett, AM; D'Angelo, HM; Hopp, SC; Kaercher, RM; Royer, SE; Wenk, GL, 2015) |
| "Nimodipine in both treatment forms prevented the memory impairment following spontaneous morphine withdrawal." | 1.38 | The effect of nimodipine on memory impairment during spontaneous morphine withdrawal in mice: Corticosterone interaction. ( Hajhashemi, V; Rabbani, M; Vaseghi, G, 2012) |
| "Both nimodipine treatments prevented the memory deficits when these were measured between 1 and 2 months after alcohol withdrawal." | 1.35 | Nimodipine prior to alcohol withdrawal prevents memory deficits during the abstinence phase. ( Brooks, SP; Croft, AP; Little, HJ; Norman, G; Shaw, SG, 2008) |
| "NMD reversed the long-term memory loss induced by PHT and VPA in the PAT." | 1.30 | Effect of nimodipine on the cognitive dysfunction induced by phenytoin and valproate in rats. ( Balakrishnan, S; Pandhi, P, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (38.89) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 7 (38.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y | 2 |
| Guo, Z | 1 |
| Peng, X | 1 |
| Xie, W | 1 |
| Chen, L | 1 |
| Tan, Z | 1 |
| Yan, B | 1 |
| Sun, Y | 1 |
| Zeng, J | 1 |
| Li, C | 1 |
| Song, P | 1 |
| Zhang, L | 1 |
| Yang, X | 1 |
| Wu, Y | 1 |
| Ma, P | 1 |
| Hopp, SC | 2 |
| D'Angelo, HM | 2 |
| Royer, SE | 2 |
| Kaercher, RM | 2 |
| Adzovic, L | 2 |
| Wenk, GL | 2 |
| Crockett, AM | 1 |
| Brooks, SP | 1 |
| Croft, AP | 1 |
| Norman, G | 1 |
| Shaw, SG | 1 |
| Little, HJ | 1 |
| Bekker, A | 1 |
| Haile, M | 1 |
| Li, YS | 1 |
| Galoyan, S | 1 |
| Garcia, E | 1 |
| Quartermain, D | 1 |
| Kamer, A | 1 |
| Blanck, T | 1 |
| Vaseghi, G | 1 |
| Rabbani, M | 1 |
| Hajhashemi, V | 1 |
| Gholamipour-Badie, H | 1 |
| Naderi, N | 1 |
| Khodagholi, F | 1 |
| Shaerzadeh, F | 1 |
| Motamedi, F | 1 |
| Corradini, I | 1 |
| Donzelli, A | 1 |
| Antonucci, F | 1 |
| Welzl, H | 1 |
| Loos, M | 1 |
| Martucci, R | 1 |
| De Astis, S | 1 |
| Pattini, L | 1 |
| Inverardi, F | 1 |
| Wolfer, D | 1 |
| Caleo, M | 1 |
| Bozzi, Y | 1 |
| Verderio, C | 1 |
| Frassoni, C | 1 |
| Braida, D | 1 |
| Clerici, M | 1 |
| Lipp, HP | 1 |
| Sala, M | 1 |
| Matteoli, M | 1 |
| Veng, LM | 1 |
| Mesches, MH | 1 |
| Browning, MD | 1 |
| Zhang, G | 1 |
| Liu, A | 1 |
| Zhou, Y | 1 |
| San, X | 1 |
| Jin, T | 1 |
| Jin, Y | 1 |
| Hütter, BO | 1 |
| Gilsbach, JM | 1 |
| Balakrishnan, S | 1 |
| Pandhi, P | 1 |
| Paróczai, M | 1 |
| Kiss, B | 1 |
| Kárpáti, E | 1 |
| Sze, KH | 1 |
| Sim, TC | 1 |
| Wong, E | 1 |
| Cheng, S | 1 |
| Woo, J | 1 |
| Sui, J | 1 |
| Xiong, Y | 1 |
| Zhang, C | 1 |
| Xu, WX | 1 |
| Guo, YP | 1 |
| Zhao, F | 1 |
2 trials available for nimodipine and Age-Related Memory Disorders
| Article | Year |
|---|---|
Effect of nimodipine on memory after cerebral infarction.
Topics: Aged; Aged, 80 and over; Atrial Fibrillation; Calcium Channel Blockers; Cerebral Infarction; Depress | 1998 |
[A clinical study of recovery of memories in 46 cases of cerebrovascular diseases].
Topics: Aged; Cerebral Infarction; Double-Blind Method; Female; Humans; Male; Memory; Memory Disorders; Midd | 1991 |
16 other studies available for nimodipine and Age-Related Memory Disorders
| Article | Year |
|---|---|
Nimodipine represses AMPK phosphorylation and excessive autophagy after chronic cerebral hypoperfusion in rats.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Brain; Calcium Channel Blockers; Calcium Channels | 2018 |
Combined use of vitamin E and nimodipine ameliorates dibutyl phthalate-induced memory deficit and apoptosis in mice by inhibiting the ERK 1/2 pathway.
Topics: Animals; Antioxidants; Apoptosis; Behavior, Animal; Calcium Channel Blockers; Calcium Signaling; Dib | 2019 |
Differential rescue of spatial memory deficits in aged rats by L-type voltage-dependent calcium channel and ryanodine receptor antagonism.
Topics: Aging; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Dantrolene; Gene Expression; Hip | 2014 |
Calcium dysregulation via L-type voltage-dependent calcium channels and ryanodine receptors underlies memory deficits and synaptic dysfunction during chronic neuroinflammation.
Topics: AIDS-Related Complex; Analysis of Variance; Animals; Calcium; Calcium Channel Blockers; Calcium Chan | 2015 |
Nimodipine prior to alcohol withdrawal prevents memory deficits during the abstinence phase.
Topics: Alcohol-Induced Disorders; Alcohols; Analysis of Variance; Animals; Body Weight; Brain; Calcium Chan | 2008 |
Nimodipine prevents memory impairment caused by nitroglycerin-induced hypotension in adult mice.
Topics: Animals; Avoidance Learning; Behavior, Animal; Blood Pressure; Calcium Channel Blockers; Cerebrovasc | 2009 |
The effect of nimodipine on memory impairment during spontaneous morphine withdrawal in mice: Corticosterone interaction.
Topics: Animals; Brain; Calcium Channel Blockers; Corticosterone; Male; Memory Disorders; Mice; Morphine; Ni | 2012 |
L-type calcium channel blockade alleviates molecular and reversal spatial learning and memory alterations induced by entorhinal amyloid pathology in rats.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Area Under Curve; Calcium Channel Blockers; Ca | 2013 |
Epileptiform activity and cognitive deficits in SNAP-25(+/-) mice are normalized by antiepileptic drugs.
Topics: Animals; Anticonvulsants; Association Learning; Brain; Carbamazepine; Cognition Disorders; Epilepsy; | 2014 |
Age-related working memory impairment is correlated with increases in the L-type calcium channel protein alpha1D (Cav1.3) in area CA1 of the hippocampus and both are ameliorated by chronic nimodipine treatment.
Topics: Aging; Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium-Calmod | 2003 |
Panax ginseng ginsenoside-Rg2 protects memory impairment via anti-apoptosis in a rat model with vascular dementia.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Dementia, Vascular; Disease Models, Animal; Dose-Res | 2008 |
Which neuropsychological deficits are hidden behind a good outcome (Glasgow = I) after aneurysmal subarachnoid hemorrhage?
Topics: Adult; Age Factors; Aphasia; Cognition Disorders; Female; Follow-Up Studies; Glasgow Coma Scale; Hum | 1993 |
Effect of nimodipine on the cognitive dysfunction induced by phenytoin and valproate in rats.
Topics: Animals; Avoidance Learning; Female; Male; Memory Disorders; Nimodipine; Phenytoin; Rats; Retention, | 1997 |
Effect of RGH-2716 on learning and memory deficits of young and aged rats in water-labyrinth.
Topics: Aging; Amnesia, Retrograde; Animals; Diazepam; Learning Disabilities; Male; Maze Learning; Memory; M | 1998 |
[Therapeutic effects of nimodipine on learning and memory of rats with traumatic brain injury].
Topics: Animals; Avoidance Learning; Brain Injuries; Calcium Channel Blockers; Female; Male; Memory Disorder | 1997 |
[Clinical studies on the improvement of failing memory by nimodipine].
Topics: Epinephrine; Female; Humans; Hypertension; Male; Memory Disorders; Middle Aged; Neuropsychological T | 1990 |