Page last updated: 2024-11-01

nimodipine and Affective Disorders

nimodipine has been researched along with Affective Disorders in 4 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Research Excerpts

ExcerptRelevanceReference
"Forty three patients with chronic alcoholism of stage II with secondary affective disorders (anxiety, subdepression) and actualization of pathological drive for alcohol in remission period were divided into 3 groups: patients were treated with nimodipine (90 mg/day during 10 days), patients were treated with nifedipine (45 mg/day during 10 days) and patients of control group (they received a placebo for 10 days)."5.11[The efficacy of calcium channel blockers in the treatment of affective disorders and pathologic drive for alcohol in patients with alcoholism in the remission period]. ( Burakov, AM; Grinenko, AIa; Karandashova, GF; Krupitskiĭ, EM; Priputina, LS; Romanova, TN; Slavina, TIu; Vostrikov, VV, 2004)
"Preliminary evidence suggests that nimodipine, an L-type calcium channel blocker, is effective in treating some patients with rapidly cycling affective disorders and some phases of Alzheimer's disease, i."5.08Nimodipine increases CSF somatostatin in affectively ill patients. ( Davis, CL; George, MS; Pazzaglia, PJ; Post, RM; Rubinow, DR, 1995)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frye, MA1
Pazzaglia, PJ2
George, MS2
Luckenbaugh, DA1
Vanderham, E1
Davis, CL2
Rubinow, DR2
Post, RM2
Krupitskiĭ, EM1
Burakov, AM1
Priputina, LS1
Vostrikov, VV1
Romanova, TN1
Karandashova, GF1
Slavina, TIu1
Grinenko, AIa1
Goodnick, PJ1

Trials

3 trials available for nimodipine and Affective Disorders

ArticleYear
Low CSF somatostatin associated with response to nimodipine in patents with affective illness.
    Biological psychiatry, 2003, Jan-15, Volume: 53, Issue:2

    Topics: Adult; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Male; Mood Disorders; Nimodipi

2003
[The efficacy of calcium channel blockers in the treatment of affective disorders and pathologic drive for alcohol in patients with alcoholism in the remission period].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2004, Volume: 104, Issue:7

    Topics: Adult; Alcoholism; Calcium Channel Blockers; Double-Blind Method; Drive; Humans; Mood Disorders; Nif

2004
Nimodipine increases CSF somatostatin in affectively ill patients.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1995, Volume: 13, Issue:1

    Topics: Adult; Bipolar Disorder; Calcium Channel Blockers; Female; Humans; Male; Middle Aged; Mood Disorders

1995

Other Studies

1 other study available for nimodipine and Affective Disorders

ArticleYear
The use of nimodipine in the treatment of mood disorders.
    Bipolar disorders, 2000, Volume: 2, Issue:3 Pt 1

    Topics: Activity Cycles; Bipolar Disorder; Calcium Channel Blockers; Catecholamines; Humans; Mood Disorders;

2000