nimodipine has been researched along with Acquired-Immune Deficiency Syndrome Dementia Complex in 3 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Galgani, S | 1 |
| Balestra, P | 1 |
| Narciso, P | 1 |
| Tozzi, V | 1 |
| Sette, P | 1 |
| Pau, F | 1 |
| Visco, G | 1 |
| Navia, BA | 1 |
| Dafni, U | 1 |
| Simpson, D | 1 |
| Tucker, T | 1 |
| Singer, E | 1 |
| McArthur, JC | 1 |
| Yiannoutsos, C | 1 |
| Zaborski, L | 1 |
| Lipton, SA | 1 |
| Gibbons, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Double-Blind, Placebo-Controlled Trial of Nimodipine for the Neurological Manifestations of HIV-1[NCT00000738] | Phase 1 | 36 participants | Interventional | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for nimodipine and Acquired-Immune Deficiency Syndrome Dementia Complex
| Article | Year |
|---|---|
Nimodipine plus zidovudine versus zidovudine alone in the treatment of HIV-1-associated cognitive deficits.
Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Calcium Channel Blockers; Case-Control Studies; Cogni | 1997 |
A phase I/II trial of nimodipine for HIV-related neurologic complications.
Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Calcium Channel Blockers; Double-Blind Method; Female | 1998 |
1 other study available for nimodipine and Acquired-Immune Deficiency Syndrome Dementia Complex
| Article | Year |
|---|---|
Is AIDS dementia due to increases in calcium?
Topics: AIDS Dementia Complex; Animals; Calcium; Hippocampus; HIV Envelope Protein gp120; Humans; Neurons; N | 1990 |