Page last updated: 2024-11-01

nimodipine and Acoustic Trauma

nimodipine has been researched along with Acoustic Trauma in 4 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Acoustic Trauma: Usually refer to hearing loss due to a single noise event such as an explosion or shotgun blast.

Research Excerpts

ExcerptRelevanceReference
" The animals were divided into 5 groups: 1) control, 2) acoustic trauma, 3) nimodipine plus acoustic trauma, 4) pentoxifylline plus acoustic trauma, and 5) pentoxifylline plus nimodipine plus acoustic trauma."7.77Protective effects of pentoxifylline and nimodipine on acoustic trauma in Guinea pig cochlea. ( Efendi, H; Kansu, L; Okar, I; Ozkarakas, H, 2011)
" The animals were divided into 5 groups: 1) control, 2) acoustic trauma, 3) nimodipine plus acoustic trauma, 4) pentoxifylline plus acoustic trauma, and 5) pentoxifylline plus nimodipine plus acoustic trauma."3.77Protective effects of pentoxifylline and nimodipine on acoustic trauma in Guinea pig cochlea. ( Efendi, H; Kansu, L; Okar, I; Ozkarakas, H, 2011)
"12 patients showed sudden deafness with a history of one day up to more than 20 years."1.27[Nimodipine (Bay e 9736) a new therapy concept in diseases of the inner ear?]. ( Theopold, HM, 1985)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kansu, L1
Ozkarakas, H1
Efendi, H1
Okar, I1
Ison, JR1
Payman, GH1
Palmer, MJ1
Walton, JP1
Boettcher, FA1
Caldwell, RK1
Gratton, MA1
White, DR1
Miles, LR1
Theopold, HM1

Other Studies

4 other studies available for nimodipine and Acoustic Trauma

ArticleYear
Protective effects of pentoxifylline and nimodipine on acoustic trauma in Guinea pig cochlea.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2011, Volume: 32, Issue:6

    Topics: Acoustic Stimulation; Animals; Calcium Channel Blockers; Cochlea; Guinea Pigs; Hearing Loss, Noise-I

2011
Nimodipine at a dose that slows ABR latencies does not protect the ear against noise.
    Hearing research, 1997, Volume: 106, Issue:1-2

    Topics: Acoustic Stimulation; Administration, Oral; Analysis of Variance; Animals; Auditory Threshold; Calci

1997
Effects of nimodipine on noise-induced hearing loss.
    Hearing research, 1998, Volume: 121, Issue:1-2

    Topics: Action Potentials; Animals; Auditory Threshold; Calcium Channel Blockers; Cochlea; Delayed-Action Pr

1998
[Nimodipine (Bay e 9736) a new therapy concept in diseases of the inner ear?].
    Laryngologie, Rhinologie, Otologie, 1985, Volume: 64, Issue:12

    Topics: Adult; Aged; Auditory Threshold; Calcium Channel Blockers; Female; Hearing Loss, Noise-Induced; Hear

1985