Page last updated: 2024-11-01

nimodipine and Acoustic Neuroma

nimodipine has been researched along with Acoustic Neuroma in 12 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Research Excerpts

ExcerptRelevanceReference
"Nimodipine levels were measured in pre- and postoperative serum and cerebrospinal fluid samples."1.40Neuroprotective efficacy of prophylactic enteral and parenteral nimodipine treatment in vestibular schwannoma surgery: a comparative study. ( Herzfeld, E; Koman, G; Prell, J; Rachinger, J; Rampp, S; Scheller, C; Scheller, K; Simmermacher, S; Strauss, C; Wienke, A; Wurm, F, 2014)
"The delayed onset of a facial paresis following termination of vasoactive treatment points to a disturbed microcirculation of the nerve as the main pathophysiological feature."1.32Delayed facial nerve paresis following acoustic neuroma resection and postoperative vasoactive treatment. ( Fahlbusch, R; Romstöck, J; Scheller, C; Strauss, C, 2004)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (41.67)29.6817
2010's5 (41.67)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Scheller, C7
Rampp, S2
Leisz, S2
Tatagiba, M3
Gharabaghi, A3
Ramina, KF3
Ganslandt, O3
Matthies, C3
Westermaier, T3
Antoniadis, G3
Pedro, MT3
Rohde, V3
von Eckardstein, K3
Scheller, K3
Strauss, C9
Hänel, P1
Klemm, A1
Kowoll, S1
Böselt, I1
Rahne, T1
Wienke, A5
Wurm, F1
Simmermacher, S2
Prell, J2
Rachinger, J1
Koman, G1
Herzfeld, E1
Bischoff, B4
Zenk, J2
Engelhorn, T2
Kretschmer, T2
Kornhuber, M2
Steighardt, J2
Richter, M2
Barker, FG2
Carter, BS1
Youssef, AS1
Downes, AE1
Vogel, AS1
Rachinger, JC1
Reinsch, M1
Kunter, U1
Neumann, J1
Sekiya, T1
Yagihashi, A1
Asano, K1
Suzuki, S1
Fahlbusch, R3
Romstöck, J3
Buchfelder, M1
Neu, M1
Berg, M1

Reviews

1 review available for nimodipine and Acoustic Neuroma

ArticleYear
Intraoperative neurophysiological monitoring in vestibular schwannoma surgery: advances and clinical implications.
    Neurosurgical focus, 2009, Volume: 27, Issue:4

    Topics: Action Potentials; Cochlear Nerve; Electromyography; Evoked Potentials, Auditory, Brain Stem; Facial

2009

Trials

5 trials available for nimodipine and Acoustic Neuroma

ArticleYear
Prophylactic nimodipine treatment improves hearing outcome after vestibular schwannoma surgery in men: a subgroup analysis of a randomized multicenter phase III trial.
    Neurosurgical review, 2021, Volume: 44, Issue:3

    Topics: Adult; Aged; Female; Hearing; Hearing Tests; Humans; Male; Middle Aged; Neuroma, Acoustic; Nimodipin

2021
Prophylactic nimodipine treatment for hearing preservation after vestibular schwannoma surgery: study protocol of a randomized multi-center phase III trial-AkniPro 2.
    Trials, 2021, Jul-22, Volume: 22, Issue:1

    Topics: Adult; Clinical Trials, Phase III as Topic; Hearing; Humans; Multicenter Studies as Topic; Neuroma,

2021
Prophylactic nimodipine treatment for cochlear and facial nerve preservation after vestibular schwannoma surgery: a randomized multicenter Phase III trial.
    Journal of neurosurgery, 2016, Volume: 124, Issue:3

    Topics: Adult; Cochlear Nerve; Cranial Nerve Injuries; Facial Nerve; Female; Humans; Male; Middle Aged; Neur

2016
Prophylactic nimodipine treatment and improvement in hearing outcome after vestibular schwannoma surgery: a combined analysis of a randomized, multicenter, Phase III trial and its pilot study.
    Journal of neurosurgery, 2017, Volume: 127, Issue:6

    Topics: Adult; Female; Hearing; Hearing Loss; Hearing Tests; Humans; Male; Middle Aged; Neuroma, Acoustic; N

2017
Vasoactive treatment for hearing preservation in acoustic neuroma surgery.
    Journal of neurosurgery, 2001, Volume: 95, Issue:5

    Topics: Adult; Aged; Deafness; Evoked Potentials, Auditory, Brain Stem; Hearing; Humans; Hydroxyethyl Starch

2001

Other Studies

6 other studies available for nimodipine and Acoustic Neuroma

ArticleYear
Neuroprotective efficacy of prophylactic enteral and parenteral nimodipine treatment in vestibular schwannoma surgery: a comparative study.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2014, Volume: 75, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Cochlear Nerve; Facial Nerve; Female; Humans; Male; Middle Aged; Neu

2014
Editorial. Nimodipine treatment.
    Journal of neurosurgery, 2017, Volume: 127, Issue:6

    Topics: Hearing; Humans; Neuroma, Acoustic; Nimodipine; Pilot Projects; Subarachnoid Hemorrhage

2017
Prophylactic intravenous nimodipine treatment in skull base surgery: pharmacokinetic aspects.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2012, Volume: 73, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Blood Pressure; Calcium Channel Blockers; Chrom

2012
Nimodipine ameliorates trauma-induced cochlear neuronal death.
    Neurological research, 2002, Volume: 24, Issue:8

    Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Death; Cochlear Nerve; Disease M

2002
Delayed facial nerve paresis following acoustic neuroma resection and postoperative vasoactive treatment.
    Zentralblatt fur Neurochirurgie, 2004, Volume: 65, Issue:3

    Topics: Adult; Electric Stimulation; Electromyography; Facial Nerve Diseases; Facial Paralysis; Female; Huma

2004
Intraoperative brainstem auditory evoked potential pattern and perioperative vasoactive treatment for hearing preservation in vestibular schwannoma surgery.
    Journal of neurology, neurosurgery, and psychiatry, 2008, Volume: 79, Issue:2

    Topics: Adult; Brain Stem; Cochlear Nerve; Deafness; Evoked Potentials, Auditory, Brain Stem; Female; Follow

2008