Page last updated: 2024-11-01

nimesulide and Reperfusion Injury

nimesulide has been researched along with Reperfusion Injury in 6 studies

nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"The main objective of the study was to determine the neuroprotective effect of allopurinol and nimesulide against the cerebral ischemic reperfusion injury in diabetic and nondiabetic rats."7.79Neuroprotective effect of allopurinol and nimesulide against cerebral ischemic reperfusion injury in diabetic rats. ( Ansari, MA; Goli, D; Hussain, SK; Mudagal, MP, 2013)
"Nimesulide is a pharmacological agent and selective COX-2 inhibitor."5.40Protective effect of nimesulide against hepatic ischemia/reperfusion injury in rats: effects on oxidant/antioxidants, DNA mutation and COX-1/COX-2 levels. ( Demiryilmaz, I; Gulapoglu, M; Kisaoglu, A; Suleyman, H; Turan, MI; Yilmaz, I, 2014)
"The main objective of the study was to determine the neuroprotective effect of allopurinol and nimesulide against the cerebral ischemic reperfusion injury in diabetic and nondiabetic rats."3.79Neuroprotective effect of allopurinol and nimesulide against cerebral ischemic reperfusion injury in diabetic rats. ( Ansari, MA; Goli, D; Hussain, SK; Mudagal, MP, 2013)
" Celecoxib (10, 20 and 40 mg/kg(-l)) was significantly more potent at aggravating ischemia-reperfusion injury as compared to nimesulide."3.73Comparative gastrointestinal toxicity of selective cyclooxygenase (COX-2) inhibitors. ( Malhotra, S; Nada, R; Pandhi, P; Shafiq, N, 2005)
"Nimesulide is a pharmacological agent and selective COX-2 inhibitor."1.40Protective effect of nimesulide against hepatic ischemia/reperfusion injury in rats: effects on oxidant/antioxidants, DNA mutation and COX-1/COX-2 levels. ( Demiryilmaz, I; Gulapoglu, M; Kisaoglu, A; Suleyman, H; Turan, MI; Yilmaz, I, 2014)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Demiryilmaz, I1
Turan, MI1
Kisaoglu, A1
Gulapoglu, M1
Yilmaz, I1
Suleyman, H1
Suleyman, Z1
Sener, E1
Kurt, N1
Comez, M1
Yapanoglu, T1
Gaur, V1
Kumar, A1
Apostolidis, D1
Ntinas, A1
Kardassis, D1
Koulouris, N1
Thomareis, O1
Karayannopoulou, G1
Vrochides, D1
Ansari, MA1
Hussain, SK1
Mudagal, MP1
Goli, D1
Shafiq, N1
Malhotra, S1
Pandhi, P1
Nada, R1

Other Studies

6 other studies available for nimesulide and Reperfusion Injury

ArticleYear
Protective effect of nimesulide against hepatic ischemia/reperfusion injury in rats: effects on oxidant/antioxidants, DNA mutation and COX-1/COX-2 levels.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:4

    Topics: Animals; Antioxidants; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; DNA Damage;

2014
The effect of nimesulide on oxidative damage inflicted by ischemia-reperfusion on the rat renal tissue.
    Renal failure, 2015, Volume: 37, Issue:2

    Topics: Animals; Antioxidants; Dose-Response Relationship, Drug; Kidney; Kidney Diseases; Male; Malondialdeh

2015
Effect of nonselective and selective COX-2 inhibitors on memory dysfunction, glutathione system, and tumor necrosis factor alpha level against cerebral ischemia reperfusion injury.
    Drug and chemical toxicology, 2012, Volume: 35, Issue:2

    Topics: Acetylcholinesterase; Animals; Behavior, Animal; Celecoxib; Cyclooxygenase 2 Inhibitors; Glutathione

2012
Nimesulide may be more efficient than allopurinol in protecting pancreas from acute ischemia/reperfusion injury in an animal model.
    Vascular and endovascular surgery, 2012, Volume: 46, Issue:8

    Topics: Allopurinol; Animals; Biomarkers; Biopsy; Cytoprotection; Disease Models, Animal; Infusions, Intrave

2012
Neuroprotective effect of allopurinol and nimesulide against cerebral ischemic reperfusion injury in diabetic rats.
    European review for medical and pharmacological sciences, 2013, Volume: 17, Issue:2

    Topics: Allopurinol; Animals; Brain Ischemia; Catalase; Diabetes Mellitus, Experimental; Female; Male; Neuro

2013
Comparative gastrointestinal toxicity of selective cyclooxygenase (COX-2) inhibitors.
    Indian journal of experimental biology, 2005, Volume: 43, Issue:7

    Topics: Animals; Celecoxib; Colitis; Cyclooxygenase Inhibitors; Gastric Mucosa; Gastrointestinal Tract; Indo

2005