nimesulide has been researched along with Pleurisy in 6 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
Pleurisy: INFLAMMATION of PLEURA, the lining of the LUNG. When PARIETAL PLEURA is involved, there is pleuritic CHEST PAIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| " According to the in vitro results, a selection of compounds exhibiting moderate to high COX-2/COX-1 selectivity ratio (from weak COX-2 preferential inhibitors to compounds displaying a celecoxib-like selectivity profile) were further evaluated in vivo in a model of lambda carrageenan-induced pleurisy in rats." | 3.75 | Pyridine analogues of nimesulide: design, synthesis, and in vitro and in vivo pharmacological evaluation as promising cyclooxygenase 1 and 2 inhibitors. ( Arslan, D; de Leval, X; Garbacki, N; Pirotte, B; Renard, JF, 2009) |
| " The N-methylsulfonamide 3a and corresponding retrosulfonamide derivative 5a were more active than standards indomethacin and nimesulide, at the same molar concentration, in carrageenan-induced pleurisy assay." | 3.70 | Synthesis and pharmacological evaluation of new flosulide analogues, synthesized from natural safrole. ( Barreiro, EJ; Fraga, CA; Lages, AS; Miranda, AL; Silva, KC, 1998) |
| " NS-398 and nimesulide dosing did not reduce thromboxane B2 production from platelets isolated from rats with carrageenin-induced pleurisy, demonstrating that at the doses used, cyclooxygenase 2 inhibitors did not inhibit cyclooxygenase 1, as platelets contain only this isoform." | 1.30 | Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation. ( Gilroy, DW; Tomlinson, A; Willoughby, DA, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lages, AS | 1 |
| Silva, KC | 1 |
| Miranda, AL | 1 |
| Fraga, CA | 1 |
| Barreiro, EJ | 1 |
| Renard, JF | 1 |
| Arslan, D | 1 |
| Garbacki, N | 1 |
| Pirotte, B | 1 |
| de Leval, X | 1 |
| Lino, RC | 1 |
| da Silva, DPB | 1 |
| Florentino, IF | 1 |
| da Silva, DM | 1 |
| Martins, JLR | 1 |
| Batista, DDC | 1 |
| Leite, KCS | 1 |
| Villavicencio, B | 1 |
| Vasconcelos, GA | 1 |
| Silva, ALP | 1 |
| de Ávila, RI | 1 |
| Verli, H | 1 |
| Valadares, MC | 1 |
| Gil, ES | 1 |
| Vaz, BG | 1 |
| Lião, LM | 1 |
| Menegatti, R | 1 |
| Costa, EA | 1 |
| Nakatsugi, S | 1 |
| Terada, N | 1 |
| Yoshimura, T | 1 |
| Horie, Y | 1 |
| Furukawa, M | 1 |
| Harada, Y | 1 |
| Kawamura, M | 1 |
| Hatanaka, K | 1 |
| Saito, M | 1 |
| Ogino, M | 1 |
| Ohno, T | 1 |
| Ogino, K | 1 |
| Yang, Q | 1 |
| Gilroy, DW | 1 |
| Tomlinson, A | 1 |
| Willoughby, DA | 1 |
6 other studies available for nimesulide and Pleurisy
| Article | Year |
|---|---|
Synthesis and pharmacological evaluation of new flosulide analogues, synthesized from natural safrole.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Disease Models, Animal; | 1998 |
Pyridine analogues of nimesulide: design, synthesis, and in vitro and in vivo pharmacological evaluation as promising cyclooxygenase 1 and 2 inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Cyclooxyge | 2009 |
Pharmacological evaluation and molecular docking of new di-tert-butylphenol compound, LQFM-091, a new dual 5-LOX/COX inhibitor.
Topics: 3T3 Cells; Animals; Carrageenan; Cell Survival; Cyclooxygenase Inhibitors; Cytokines; Edema; Female; | 2017 |
Effects of nimesulide, a preferential cyclooxygenase-2 inhibitor, on carrageenan-induced pleurisy and stress-induced gastric lesions in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; C | 1996 |
Differing profiles of prostaglandin formation inhibition between selective prostaglandin H synthase-2 inhibitors and conventional NSAIDs in inflammatory and non-inflammatory sites of the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygen | 1998 |
Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclo | 1998 |