nimesulide has been researched along with Pain in 51 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the safety and efficacy of fixed-dose combination tablets of naproxen/esomeprazole magnesium and nimesulide/pantoprazole to determine if both regimens are equally suited to relieve pain in patients with osteoarticular diseases and dyspeptic symptoms." | 9.27 | Efficacy and safety of a fixed-dose combination of nimesulide/pantoprazole compared to naproxen/esomeprazole for pain relief in patients with osteoarticular diseases and dyspeptic symptoms. ( Amazonas, RB; Bocchi de Oliveira, MF; Ecclissato, C; Macêdo, EA; Pott Júnior, H; Scheinberg, M, 2018) |
| "To compare the time to presentation of the analgetic and anti-inflammatory effects of granulated and tablet nimesulide and sodium diclofenac since the start of therapy for gouty arthritis (GA)." | 9.12 | [Comparison of the time to analgetic and anti-inflammatory effect in the treatment of gouty arthritis with nimesulide and sodium diclofenac]. ( Barskova, VG; Eliseev, MS; Kudaeva, FM; Nasonova, VA, 2007) |
| "An evaluation of clinical efficacy of nizer versus nimesulide tablets was undertaken in 118 patients suffering from otitis media." | 9.10 | Evaluation of efficacy of nizer versus nimesulide tablets in otitis media. ( Dasgupta, KS; Deshpande, AS; Patel, S; Vedi, JN, 2002) |
| "Nimesulide was compared with vehicle in groups of 4-10 rats that were randomly tested with different models of pain." | 9.10 | Central components of the analgesic/antihyperalgesic effect of nimesulide: studies in animal models of pain and hyperalgesia. ( Greco, R; Nappi, G; Sandrini, G; Tassorelli, C, 2003) |
| "The present data confirm our previous observations in patients with rheumatoid arthritis, further suggesting that nimesulide represents an effective agent for the treatment of joint pain, with particular reference to the rapid onset of its analgesic effect." | 9.10 | A randomised, double-blind, clinical trial comparing the efficacy of nimesulide, celecoxib and rofecoxib in osteoarthritis of the knee. ( Bianchi, M; Broggini, M, 2003) |
| "The clinical efficacy and the tolerability of nimesulide (100 mg bid) and naproxen sodium (550 mg bid) in the treatment of tendinitis and bursitis were evaluated in a multicentre double-blind study over a 14-day period." | 9.07 | Treatment of tendinitis and bursitis: a comparison of nimesulide and naproxen sodium in a double-blind parallel trial. ( Buyse, H; Lecomte, J; Monti, T; Taymans, J, 1994) |
| " Nimesulide have been studied in a double blind study compared with flurbiprofen, in 98 patients aged between 18 and 75 suffering from pain-inflammatory pathologies of ENT nature." | 9.07 | [Clinical study of the efficacy of and tolerance to nimesulide in suppository formulation in pain-inflammatory pathologies of the ear, nose, and throat]. ( Lomeo, G; Monea, P; Rossi, M; Scaricabarozzi, I; Trezzani, R; Tringali, G, 1991) |
| "A multicentric trial was carried out to assess the therapeutic efficacy and tolerability of nimesulide in the treatment of patients with osteoarthritis." | 9.07 | Post-marketing survey of nimesulide in the short-term treatment of osteoarthritis. ( Beretta, A; Mele, G; Montagnani, G; Pochobradsky, MG, 1991) |
| "A double-blind crossover study was carried out to evaluate the therapeutic efficacy of nimesulide and its effects on uterine activity, menstrual fluid prostaglandin F, and pain in women suffering from primary dysmenorrhea." | 9.06 | Alterations in intrauterine pressure, menstrual fluid prostaglandin F levels, and pain in dysmenorrheic women treated with nimesulide. ( Pulkkinen, MO, 1987) |
| "Nimesulide is a new non-steroidal anti-inflammatory analgesic agent given orally or rectally on a twice daily basis in a number of inflammatory and pain states." | 8.77 | Nimesulide. A preliminary review of its pharmacological properties and therapeutic efficacy in inflammation and pain states. ( Brogden, RN; Ward, A, 1988) |
| "Based on the available evidence, the CRGN concluded that nimesulide remains an effective and safe therapeutic choice for the treatment of various painful inflammatory conditions, with a rapid onset of analgesic activity and an overall positive benefit/risk profile." | 7.73 | Nimesulide -- a multifactorial approach to inflammation and pain: scientific and clinical consensus. ( Rainsford, KD, 2006) |
| "Nimesulide treatment brought about an immediate and significant improvement in over-all pain, exudation, oedema and headache and produced a rapid lowering in body temperature." | 6.65 | Nimesulide for the treatment of painful inflammatory process in the ear, nose and throat areas: a double-blind controlled study with benzydamine. ( Milvio, C, 1984) |
| "Pain peaks occurred after 6 h (nimesulide-placebo [N-P] group) and 8 h (nimesulide group)." | 5.51 | Effect of preemptive photobiomodulation associated with nimesulide on the postsurgical outcomes, oxidative stress, and quality of life after third molar surgery: a randomized, split-mouth, controlled clinical trial. ( Cesário, FRAS; Cetira Filho, EL; Choquenaira-Quispe, C; Costa, FWG; da Cruz Fonseca, SG; de Aguiar, ASW; de Sousa Nogueira, G; de Sousa, AVC; Silva, PGB; Wong, DVT, 2022) |
| "This study investigated the safety and efficacy of fixed-dose combination tablets of naproxen/esomeprazole magnesium and nimesulide/pantoprazole to determine if both regimens are equally suited to relieve pain in patients with osteoarticular diseases and dyspeptic symptoms." | 5.27 | Efficacy and safety of a fixed-dose combination of nimesulide/pantoprazole compared to naproxen/esomeprazole for pain relief in patients with osteoarticular diseases and dyspeptic symptoms. ( Amazonas, RB; Bocchi de Oliveira, MF; Ecclissato, C; Macêdo, EA; Pott Júnior, H; Scheinberg, M, 2018) |
| "To assess whether oral administration of 100 mg of nimesulide reduces pain during or after a hysterosalpingography (HSG) performed with disposable balloon catheters." | 5.13 | Strategies to minimize discomfort during diagnostic hysterosalpingography with disposable balloon catheters: a randomized placebo-controlled study with oral nonsteroidal premedication. ( Anserini, P; De Caro, G; Delfino, F; Ferraiolo, A; Menoni, S; Remorgida, V, 2008) |
| "Nimesulide is available in gel formulation and applied mainly for topical pain management." | 5.12 | The diffusion of nimesulide gel into synovial fluid: a comparison between administration routes. ( Bolay, B; Erdogan, F; Ergün, H; Gökay, NS; Gulmez, SE; Tulunay, FC, 2006) |
| "To compare the time to presentation of the analgetic and anti-inflammatory effects of granulated and tablet nimesulide and sodium diclofenac since the start of therapy for gouty arthritis (GA)." | 5.12 | [Comparison of the time to analgetic and anti-inflammatory effect in the treatment of gouty arthritis with nimesulide and sodium diclofenac]. ( Barskova, VG; Eliseev, MS; Kudaeva, FM; Nasonova, VA, 2007) |
| "An evaluation of clinical efficacy of nizer versus nimesulide tablets was undertaken in 118 patients suffering from otitis media." | 5.10 | Evaluation of efficacy of nizer versus nimesulide tablets in otitis media. ( Dasgupta, KS; Deshpande, AS; Patel, S; Vedi, JN, 2002) |
| "Nimesulide was compared with vehicle in groups of 4-10 rats that were randomly tested with different models of pain." | 5.10 | Central components of the analgesic/antihyperalgesic effect of nimesulide: studies in animal models of pain and hyperalgesia. ( Greco, R; Nappi, G; Sandrini, G; Tassorelli, C, 2003) |
| "The present data confirm our previous observations in patients with rheumatoid arthritis, further suggesting that nimesulide represents an effective agent for the treatment of joint pain, with particular reference to the rapid onset of its analgesic effect." | 5.10 | A randomised, double-blind, clinical trial comparing the efficacy of nimesulide, celecoxib and rofecoxib in osteoarthritis of the knee. ( Bianchi, M; Broggini, M, 2003) |
| "The clinical efficacy and the tolerability of nimesulide (100 mg bid) and naproxen sodium (550 mg bid) in the treatment of tendinitis and bursitis were evaluated in a multicentre double-blind study over a 14-day period." | 5.07 | Treatment of tendinitis and bursitis: a comparison of nimesulide and naproxen sodium in a double-blind parallel trial. ( Buyse, H; Lecomte, J; Monti, T; Taymans, J, 1994) |
| "The gastric tolerability of nimesulide, a new nonsteroidal anti-inflammatory drug (NSAID), was compared with diclofenac, an established NSAID for the treatment of osteoarthritis (OA)." | 5.07 | Double-blind study evaluating by endoscopy the tolerability of nimesulide and diclofenac on the gastric mucosa in osteoarthritic patients. ( Almeida, H; Cunha, MJ; Macciocchi, A; Porto, A, 1994) |
| " Nimesulide have been studied in a double blind study compared with flurbiprofen, in 98 patients aged between 18 and 75 suffering from pain-inflammatory pathologies of ENT nature." | 5.07 | [Clinical study of the efficacy of and tolerance to nimesulide in suppository formulation in pain-inflammatory pathologies of the ear, nose, and throat]. ( Lomeo, G; Monea, P; Rossi, M; Scaricabarozzi, I; Trezzani, R; Tringali, G, 1991) |
| "A multicentric trial was carried out to assess the therapeutic efficacy and tolerability of nimesulide in the treatment of patients with osteoarthritis." | 5.07 | Post-marketing survey of nimesulide in the short-term treatment of osteoarthritis. ( Beretta, A; Mele, G; Montagnani, G; Pochobradsky, MG, 1991) |
| "A double-blind crossover study was carried out to evaluate the therapeutic efficacy of nimesulide and its effects on uterine activity, menstrual fluid prostaglandin F, and pain in women suffering from primary dysmenorrhea." | 5.06 | Alterations in intrauterine pressure, menstrual fluid prostaglandin F levels, and pain in dysmenorrheic women treated with nimesulide. ( Pulkkinen, MO, 1987) |
| "This review summarizes the principal therapeutic responses to the preferential COX-2 NSAID, nimesulide, in treating musculo-skeletal joint symptoms and various acute and chronic pain conditions and the mode of action in relation to therapy in these states." | 4.83 | Current status of the therapeutic uses and actions of the preferential cyclo-oxygenase-2 NSAID, nimesulide. ( Rainsford, KD, 2006) |
| "Nimesulide is a new non-steroidal anti-inflammatory analgesic agent given orally or rectally on a twice daily basis in a number of inflammatory and pain states." | 4.77 | Nimesulide. A preliminary review of its pharmacological properties and therapeutic efficacy in inflammation and pain states. ( Brogden, RN; Ward, A, 1988) |
| "A 49-year-old woman presented at the emergency department, with acute hepatic failure, 2 weeks after taking nimesulide." | 3.83 | Autoimmune hepatitis unmasked by nimesulide. ( Brandão, I; Caridade, S; Fonseca, M; Magalhães, R, 2016) |
| "7-Hydroxycoumarin (umbelliferone, 1), the main metabolite of coumarin, has been reported to produce potent antinociceptive effects in animal models of pain." | 3.77 | Mechanisms involved in the antinociceptive effects of 7-hydroxycoumarin. ( Barbosa Filho, JM; Couto, RD; de Lima, FO; Nonato, FR; Nunes, XP; Ribeiro dos Santos, R; Soares, MB; Villarreal, CF, 2011) |
| " The newly synthesized compounds were screened for analgesic and anti-inflammatory activities on acetic acid induced writhing in mice and carrageenan induced paw oedema in rats." | 3.76 | In-vivo analgesic and anti-inflammatory activities of newly synthesized benzimidazole derivatives. ( Achar, KC; Hosamani, KM; Seetharamareddy, HR, 2010) |
| "A model of visceral pain consisting of intraperitoneal injection of acetic acid (writhing test) was used." | 3.75 | Guaifenesin enhances the analgesic potency of ibuprofen, nimesulide and celecoxib in mice. ( Dolezal, T; Krsiak, M; Sliva, J; Sykora, D; Vosmanska, M, 2009) |
| "Based on the available evidence, the CRGN concluded that nimesulide remains an effective and safe therapeutic choice for the treatment of various painful inflammatory conditions, with a rapid onset of analgesic activity and an overall positive benefit/risk profile." | 3.73 | Nimesulide -- a multifactorial approach to inflammation and pain: scientific and clinical consensus. ( Rainsford, KD, 2006) |
| " The oral administration of aspartame (2-16mg/kg, po) significantly increased the pain threshold against acetic acid-induced writhes in mice." | 3.73 | Possible analgesic and anti-inflammatory interactions of aspartame with opioids and NSAIDs. ( Jain, NK; Kulkarni, SK; Sharma, S, 2005) |
| "This study demonstrates that CSF biomarker profiles, as detected by SELDI technology, can consistently and reproducibly differentiate inflammatory from neuropathic pain, and reflect the analgesic action produced by the preferential COX-2 inhibitor, nimesulide." | 3.72 | High-throughput proteomics and protein biomarker discovery in an experimental model of inflammatory hyperalgesia: effects of nimesulide. ( Bianchi, M; Gineste, C; Ho, L; Pasinetti, GM; Pompl, P, 2003) |
| "Tizanidine, an alpha2-adrenergic receptor agonist with myospasmolytic action, is indicated for the treatment of back pain either as monotherapy or in combination with nonsteridal anti-inflammatory drugs (NSAIDs)." | 3.71 | Modulation of NSAID-induced antinociceptive and anti-inflammatory effects by alpha2-adrenoceptor agonists with gastroprotective effects. ( Jain, NK; Kulkarni, SK; Singh, A, 2002) |
| " Rolipram, a selective PDE IV inhibitor and theophylline a nonspecific PDE inhibitor exerted dose dependent analgesic and anti-inflammatory effect against acetic acid-induced writhing in mice and carrageenan-induced paw edema in rats, respectively." | 3.70 | Analgesic and anti-inflammatory effects of phosphodiesterase inhibitors. ( Jain, NK; Kulkarni, SK; Kumar, A, 2000) |
| "Osteoarthritis (OA) affects mainly older people who are more sensitive to adverse effects of classic nonsteroidal anti-inflammatory drugs." | 2.73 | Efficacy and safety of topical nimesulide in the treatment of knee osteoarthritis. ( Bodur, H; Ergün, H; Külcü, D; Kutlay, S; Tulunay, FC, 2007) |
| "Nimesulide was studied in comparison with paracetamol, according to a double-blind technique." | 2.67 | Pilot study of the antipyretic and analgesic activity of nimesulide paediatric suppositories. ( D'Apuzzo, V; Monti, T, 1992) |
| "Nimesulide treatment brought about an immediate and significant improvement in over-all pain, exudation, oedema and headache and produced a rapid lowering in body temperature." | 2.65 | Nimesulide for the treatment of painful inflammatory process in the ear, nose and throat areas: a double-blind controlled study with benzydamine. ( Milvio, C, 1984) |
| "Nimesulide had a potency lower than those of celecoxib, and DFU." | 1.34 | Additive interaction of intraperitoneal dexmedetomidine and topical nimesulide, celecoxib, and DFU for antinociception. ( Bagcivan, I; Cetin, A; Gulturk, S; Gursoy, S; Karadas, B; Kaya, T; Parlak, A, 2007) |
| " The aim of the present study was to evaluate the comparative efficacy of intramuscularly injected nimesulide with that of diclofenac and to elucidate the pharmacokinetic profile of this formulation." | 1.30 | Comparative analgesic activity of nimesulide and diclofenac by intramuscular route: correlation with pharmacokinetic profile of nimesulide. ( Gupta, SK; Mathur, P; Sengupta, S; Velpandian, T, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (7.84) | 18.7374 |
| 1990's | 13 (25.49) | 18.2507 |
| 2000's | 25 (49.02) | 29.6817 |
| 2010's | 8 (15.69) | 24.3611 |
| 2020's | 1 (1.96) | 2.80 |
| Authors | Studies |
|---|---|
| Duarte, CD | 1 |
| Tributino, JL | 1 |
| Lacerda, DI | 1 |
| Martins, MV | 1 |
| Alexandre-Moreira, MS | 1 |
| Dutra, F | 1 |
| Bechara, EJ | 1 |
| De-Paula, FS | 1 |
| Goulart, MO | 1 |
| Ferreira, J | 1 |
| Calixto, JB | 1 |
| Nunes, MP | 1 |
| Bertho, AL | 1 |
| Miranda, AL | 1 |
| Barreiro, EJ | 1 |
| Fraga, CA | 1 |
| Achar, KC | 1 |
| Hosamani, KM | 1 |
| Seetharamareddy, HR | 1 |
| de Lima, FO | 1 |
| Nonato, FR | 1 |
| Couto, RD | 1 |
| Barbosa Filho, JM | 1 |
| Nunes, XP | 1 |
| Ribeiro dos Santos, R | 1 |
| Soares, MB | 1 |
| Villarreal, CF | 1 |
| Cetira Filho, EL | 1 |
| Silva, PGB | 1 |
| Wong, DVT | 1 |
| Choquenaira-Quispe, C | 1 |
| Cesário, FRAS | 1 |
| de Sousa Nogueira, G | 1 |
| de Sousa, AVC | 1 |
| de Aguiar, ASW | 1 |
| da Cruz Fonseca, SG | 1 |
| Costa, FWG | 1 |
| Scheinberg, M | 1 |
| Pott Júnior, H | 1 |
| Macêdo, EA | 1 |
| Bocchi de Oliveira, MF | 1 |
| Ecclissato, C | 1 |
| Amazonas, RB | 1 |
| Abdelkader, H | 1 |
| Abdallah, OY | 1 |
| Salem, H | 1 |
| Alani, AW | 1 |
| Alany, RG | 1 |
| Kvasnovsky, CL | 1 |
| Aujla, U | 1 |
| Bjarnason, I | 1 |
| Magalhães, R | 1 |
| Fonseca, M | 1 |
| Brandão, I | 1 |
| Caridade, S | 1 |
| Prabhu, VV | 1 |
| Sliva, J | 1 |
| Dolezal, T | 1 |
| Sykora, D | 1 |
| Vosmanska, M | 1 |
| Krsiak, M | 1 |
| Staniaszek, LE | 1 |
| Norris, LM | 1 |
| Kendall, DA | 1 |
| Barrett, DA | 1 |
| Chapman, V | 1 |
| Mattia, C | 1 |
| Ciarcia, S | 1 |
| Muhindo, A | 1 |
| Coluzzi, F | 1 |
| Kullich, WC | 1 |
| Niksic, F | 1 |
| Klein, G | 1 |
| Jain, NK | 5 |
| Kulkarni, SK | 5 |
| Singh, A | 3 |
| Monteforte, P | 1 |
| Rovetta, G | 1 |
| Dasgupta, KS | 1 |
| Deshpande, AS | 1 |
| Vedi, JN | 1 |
| Patel, S | 1 |
| Camu, F | 1 |
| Shi, L | 1 |
| Vanlersberghe, C | 1 |
| Gineste, C | 1 |
| Ho, L | 1 |
| Pompl, P | 1 |
| Bianchi, M | 3 |
| Pasinetti, GM | 1 |
| Tassorelli, C | 1 |
| Greco, R | 1 |
| Sandrini, G | 1 |
| Nappi, G | 1 |
| Broggini, M | 1 |
| Patil, CS | 1 |
| Sarkar, ML | 1 |
| Sharma, S | 1 |
| Erdogan, F | 1 |
| Ergün, H | 2 |
| Gökay, NS | 1 |
| Gulmez, SE | 1 |
| Bolay, B | 1 |
| Tulunay, FC | 2 |
| Rainsford, KD | 2 |
| Karadas, B | 1 |
| Kaya, T | 1 |
| Gulturk, S | 1 |
| Parlak, A | 1 |
| Gursoy, S | 1 |
| Cetin, A | 1 |
| Bagcivan, I | 1 |
| Martucci, C | 1 |
| Ferrario, P | 1 |
| Franchi, S | 1 |
| Sacerdote, P | 1 |
| Kudaeva, FM | 1 |
| Eliseev, MS | 1 |
| Barskova, VG | 1 |
| Nasonova, VA | 1 |
| Külcü, D | 1 |
| Kutlay, S | 1 |
| Bodur, H | 1 |
| Anserini, P | 1 |
| Delfino, F | 1 |
| Ferraiolo, A | 1 |
| Remorgida, V | 1 |
| Menoni, S | 1 |
| De Caro, G | 1 |
| Van Zundert, J | 1 |
| Van Boxem, K | 1 |
| Milvio, C | 1 |
| Gabbrielli, G | 1 |
| Binazzi, P | 1 |
| Scaricabarozzi, I | 3 |
| Massi, GB | 1 |
| Facchini, R | 1 |
| Selva, G | 1 |
| Peretti, G | 1 |
| Tognella, S | 1 |
| Lecomte, J | 1 |
| Buyse, H | 1 |
| Taymans, J | 1 |
| Monti, T | 2 |
| Porto, A | 1 |
| Almeida, H | 1 |
| Cunha, MJ | 1 |
| Macciocchi, A | 1 |
| Gupta, SK | 1 |
| Velpandian, T | 1 |
| Mathur, P | 1 |
| Sengupta, S | 1 |
| Matsumoto, H | 1 |
| Naraba, H | 1 |
| Ueno, A | 1 |
| Fujiyoshi, T | 1 |
| Murakami, M | 1 |
| Kudo, I | 1 |
| Oh-ishi, S | 1 |
| Zgradie, I | 1 |
| Kumar, A | 1 |
| Dionigi, R | 1 |
| Interdonato, PF | 1 |
| D'Apuzzo, V | 1 |
| Rossi, M | 1 |
| Monea, P | 1 |
| Lomeo, G | 1 |
| Tringali, G | 1 |
| Trezzani, R | 1 |
| Pochobradsky, MG | 1 |
| Mele, G | 1 |
| Beretta, A | 1 |
| Montagnani, G | 1 |
| Cantarelli, A | 1 |
| Giannunzio, D | 1 |
| Ligorio, L | 1 |
| Mapelli, A | 1 |
| Veca, G | 1 |
| Gallucci, M | 1 |
| Toscani, F | 1 |
| Ward, A | 1 |
| Brogden, RN | 1 |
| Pulkkinen, MO | 1 |
| Finiguerra, M | 1 |
| Conti, P | 1 |
| Gallone, F | 1 |
| Ferraris, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Parallel Study, Double-blind, Randomized, to Compare the Safety of Two Therapies for the Treatment of Osteoarticular Inflammation in Dyspeptic Patients.[NCT01670552] | Phase 3 | 490 participants (Actual) | Interventional | 2016-02-17 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for nimesulide and Pain
| Article | Year |
|---|---|
Nonsteroidal anti-inflammatory drugs and exacerbations of inflammatory bowel disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Clinical Trials as Topic; Cyclooxygenase 2; Cycl | 2015 |
[Nimesulide: 25 years later].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Italy; Pain; Sulfonamides | 2010 |
The role of COX-2 inhibitors in pain modulation.
Topics: Cyclooxygenase Inhibitors; Humans; In Vitro Techniques; Nociceptors; Pain; Prostaglandin Antagonists | 2003 |
Current status of the therapeutic uses and actions of the preferential cyclo-oxygenase-2 NSAID, nimesulide.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Humans; Inflammation; | 2006 |
Nimesulide. A preliminary review of its pharmacological properties and therapeutic efficacy in inflammation and pain states.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Inflammation; Pain; Sulfonamides | 1988 |
23 trials available for nimesulide and Pain
| Article | Year |
|---|---|
Effect of preemptive photobiomodulation associated with nimesulide on the postsurgical outcomes, oxidative stress, and quality of life after third molar surgery: a randomized, split-mouth, controlled clinical trial.
Topics: Double-Blind Method; Edema; Humans; Low-Level Light Therapy; Molar, Third; Mouth; Oxidative Stress; | 2022 |
Efficacy and safety of a fixed-dose combination of nimesulide/pantoprazole compared to naproxen/esomeprazole for pain relief in patients with osteoarticular diseases and dyspeptic symptoms.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Double-Blind Method; Dysp | 2018 |
A comparative clinical trial evaluating efficacy and safety of fixed dose combination of nimesulide (100 mg) and racemethionine (50 mg) (namsafe) versus reference drug (nimesulide) and other NSAIDs in the treatment of osteoarthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Female; Health Status Indicators; Humans | 2008 |
Changes in size of periarthritis calcifications in patients with painful shoulder treated with injectable disodium-clodronate.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Calcinosis; Clodro | 2002 |
Evaluation of efficacy of nizer versus nimesulide tablets in otitis media.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Child; Cyclodextrins | 2002 |
Central components of the analgesic/antihyperalgesic effect of nimesulide: studies in animal models of pain and hyperalgesia.
Topics: Analgesia; Animals; Brain; Disease Models, Animal; Gene Expression; Genes, fos; Hyperalgesia; Male; | 2003 |
A randomised, double-blind, clinical trial comparing the efficacy of nimesulide, celecoxib and rofecoxib in osteoarthritis of the knee.
Topics: Adult; Aged; Analysis of Variance; Celecoxib; Double-Blind Method; Female; Humans; Knee; Lactones; M | 2003 |
The diffusion of nimesulide gel into synovial fluid: a comparison between administration routes.
Topics: Administration, Cutaneous; Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Diffusion; | 2006 |
[Comparison of the time to analgetic and anti-inflammatory effect in the treatment of gouty arthritis with nimesulide and sodium diclofenac].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Diclofenac; Female; Humans; Male; Pain; P | 2007 |
Efficacy and safety of topical nimesulide in the treatment of knee osteoarthritis.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female | 2007 |
Strategies to minimize discomfort during diagnostic hysterosalpingography with disposable balloon catheters: a randomized placebo-controlled study with oral nonsteroidal premedication.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Catheterization; Disposable Eq | 2008 |
Nimesulide for the treatment of painful inflammatory process in the ear, nose and throat areas: a double-blind controlled study with benzydamine.
Topics: Adult; Anti-Inflammatory Agents; Benzydamine; Double-Blind Method; Drug Evaluation; Female; Humans; | 1984 |
Nimesulide in the treatment of mastalgia.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Breast Diseases; Female; Humans; M | 1993 |
Tolerability of nimesulide and ketoprofen in paediatric patients with traumatic or surgical fractures.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Child; Female; Fractures, Bone; Humans; Ketopro | 1993 |
Treatment of tendinitis and bursitis: a comparison of nimesulide and naproxen sodium in a double-blind parallel trial.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Bursitis; Double-Blind Method; Female; Humans; Male; | 1994 |
Double-blind study evaluating by endoscopy the tolerability of nimesulide and diclofenac on the gastric mucosa in osteoarthritic patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Endoscopy; Female; Gastric | 1994 |
Comparison of therapeutic efficacy of nimesulide and diclofenac in patients with degenerative joint diseases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dou | 1999 |
[Evaluation of the efficacy and tolerability of nimesulide in the treatment of mastodynia].
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Breast Diseases; Drug Evaluation; Female | 1992 |
Pilot study of the antipyretic and analgesic activity of nimesulide paediatric suppositories.
Topics: Acetaminophen; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschoo | 1992 |
[Clinical study of the efficacy of and tolerance to nimesulide in suppository formulation in pain-inflammatory pathologies of the ear, nose, and throat].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Flurbiprofen; Hum | 1991 |
Post-marketing survey of nimesulide in the short-term treatment of osteoarthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Male; Middle Aged; Osteoarthri | 1991 |
[Comparison of nimesulide and naproxen sodium in the control of cancer pain].
Topics: Double-Blind Method; Humans; Naproxen; Neoplasms; Pain; Sulfonamides | 1991 |
Alterations in intrauterine pressure, menstrual fluid prostaglandin F levels, and pain in dysmenorrheic women treated with nimesulide.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Dysmenorrhea; Female; Humans; Menstruation; Pain; Pr | 1987 |
23 other studies available for nimesulide and Pain
| Article | Year |
|---|---|
Synthesis, pharmacological evaluation and electrochemical studies of novel 6-nitro-3,4-methylenedioxyphenyl-N-acylhydrazone derivatives: Discovery of LASSBio-881, a new ligand of cannabinoid receptors.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Arachidonic Acid; Arachidonic Acids; Bi | 2007 |
In-vivo analgesic and anti-inflammatory activities of newly synthesized benzimidazole derivatives.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzimidazoles; Carrageen | 2010 |
Mechanisms involved in the antinociceptive effects of 7-hydroxycoumarin.
Topics: Analgesics; Animals; Brazil; Dinoprostone; Edema; Freund's Adjuvant; Mice; Models, Animal; Molecular | 2011 |
Eutectic, monotectic and immiscibility systems of nimesulide with water-soluble carriers: phase equilibria, solid-state characterisation and in-vivo/pharmacodynamic evaluation.
Topics: Acetic Acid; Animals; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Cyclooxygenase | 2014 |
Autoimmune hepatitis unmasked by nimesulide.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Hepatitis, Autoimmune; Humans; Liver; Liver Cirrhos | 2016 |
Guaifenesin enhances the analgesic potency of ibuprofen, nimesulide and celecoxib in mice.
Topics: Acetic Acid; Analgesia; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cele | 2009 |
Effects of COX-2 inhibition on spinal nociception: the role of endocannabinoids.
Topics: Animals; Cannabinoid Receptor Modulators; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response | 2010 |
Effect of nimesulide on metalloproteinases and matrix degradation in osteoarthritis: a pilot clinical study.
Topics: Acute Disease; Adult; Aged; Analysis of Variance; Cartilage Oligomeric Matrix Protein; Cyclooxygenas | 2002 |
Modulation of NSAID-induced antinociceptive and anti-inflammatory effects by alpha2-adrenoceptor agonists with gastroprotective effects.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Drug Synergi | 2002 |
High-throughput proteomics and protein biomarker discovery in an experimental model of inflammatory hyperalgesia: effects of nimesulide.
Topics: Analysis of Variance; Animals; Biomarkers; Cerebrospinal Fluid Proteins; Constriction; Cyclooxygenas | 2003 |
Modulatory effect of cyclooxygenase inhibitors on sildenafil-induced antinociception.
Topics: Animals; Carrageenan; Cyclic GMP; Cyclooxygenase Inhibitors; Diclofenac; Drug Synergism; Enzyme Inhi | 2003 |
Pain--the enigmatic entity.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Interactions; | 2004 |
Possible analgesic and anti-inflammatory interactions of aspartame with opioids and NSAIDs.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; | 2005 |
Nimesulide -- a multifactorial approach to inflammation and pain: scientific and clinical consensus.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Humans | 2006 |
Additive interaction of intraperitoneal dexmedetomidine and topical nimesulide, celecoxib, and DFU for antinociception.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Animals; Celecoxib; Cyclooxygenase 2 Inhibitors; | 2007 |
Increased tumor necrosis factor-alpha and prostaglandin E2 concentrations in the cerebrospinal fluid of rats with inflammatory hyperalgesia: the effects of analgesic drugs.
Topics: Acetaminophen; Administration, Oral; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anima | 2007 |
World Institute of Pain (WIP)--Fourth World Congress.
Topics: Animals; Back Pain; Clinical Trials as Topic; Humans; Ketamine; Neoplasms; Pain; Pain Management; Ra | 2007 |
Nimesulide. New clinical opportunities.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Fever; Humans; Inflammation; Pain; Platelet Aggregation; Su | 1993 |
Comparative analgesic activity of nimesulide and diclofenac by intramuscular route: correlation with pharmacokinetic profile of nimesulide.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cycloox | 1998 |
Induction of cyclooxygenase-2 causes an enhancement of writhing response in mice.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; C | 1998 |
Analgesic and anti-inflammatory effects of phosphodiesterase inhibitors.
Topics: Abdominal Pain; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageen | 2000 |
Role of cysteinyl leukotrienes in nociceptive and inflammatory conditions in experimental animals.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cell Migration Inhib | 2001 |
[A new non-steroidal anti-inflammatory agent, nimesulide, in the treatment of inflammatory forms of pneumologic importance].
Topics: Adult; Aged; Anti-Inflammatory Agents; Bronchitis; Bronchopneumonia; Drug Evaluation; Female; Humans | 1986 |